iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pma-094323

UUCD1 version

UUC-PeM-00536

Ensembl Protein ID

ENSPMAP00000005242.1

UniProt Accession

S4RJ60; S4RJ60_PETMA

Protein Name

Ubiquitinyl hydrolase 1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPMAG00000004762.1	ENSPMAT00000005261.1	ENSPMAP00000005242.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	6.30e-76	254.9	132	472

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqq 90
           Gl NlgNtC+mN+++Q+L+++p lr+++l+ +++++     ++p+++l++++ +lf+e+ +  +    p  l+ + +      ++ ++ 
   Q: 132  GLVNLGNTCFMNCIVQALTHTPLLRDFFLS-DRHRCGM---PSPEACLVCEMCRLFQEVGNPARCLAPPFCLVPIARCQ---CRKIMEF 213
           9*****************************.9999987...589***************88888888888888877633...3466777 PP
   S: 91   DaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgk 179
           D +  l+  +     ++            +       + ++++++++ +++i+++F g l+s+++c+ c+ vs++ +pf+d+sl++pg+
   Q: 214  DLSMTLHSGVCWPFFSC-----------IG-----DANGKRSNNPNHCNCIIDQIFTGGLQSDVTCQVCQGVSTTIDPFWDISLDLPGS 286
           76555554444444444...........22.....23345678899999**************************************** PP
   S: 180  eetkke......................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksr 246
           ++   +                      +l+dcL+ ft++e+l ++ k++c+ c+++qe++k+l+++klP v ++hLkRf  +++   r
   Q: 287  SSPFWPlsptaesgipngggplipagptTLNDCLRRFTRPEHLGSSAKIKCNGCHSYQESTKQLTMRKLPIVACFHLKRF--EHSARLR 373
           *887779*************************************************************************..5566799 PP
   S: 247  ekinkkvefpleLdlspfctspeekqke..........kkkYeLiavvvHsGslssGHYvayvknekgkWllfdDskVtevkeeevlee 325
           +ki+++v+fpleLd++pf++s++++  +          ++kY+L+avv+H+G+l+sGHY+++++ ++++W+++dD  +t+ + ++vl  
   Q: 374  RKISTYVSFPLELDMTPFMNSSKDSRVNgqyqtgestnENKYSLFAVVNHQGTLESGHYTSFIRLHRDQWFKCDDAVITHASVTDVLD- 461
           9****************999944444335666666666**************************************************. PP
   S: 326  tgstaYvlfYkrr 338
             s++Y+lfY+++
   Q: 462  --SEGYLLFYHKQ 472
           ..********985 PP

Organism

Petromyzon marinus

Protein Sequence
(Fasta)

VWTDAPLPPA LQARSCVCHL CGAHFGRLHA CLHCIYFGCF ARRHIHEHAK AKRHPLSMDL 60
YHGTVFCLLC QDYVYDRDLE LVSREEQRRA WRLQGFGDRY IGWEPSRREL ELLKQNPKRR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGTGGACGG ACGCCCCCCT CCCCCCGGCC CTGCAGGCCC GTTCGTGCGT GTGCCACTTG 60
TGCGGCGCCC ACTTTGGCCG CCTGCACGCC TGCCTGCACT GCATCTACTT CGGCTGCTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00443--UCH
PF02148--zf-UBP

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001343	Ailuropoda melanoleuca	69.71	0.00e+00	717.00
IUUC-Atr-002653	Amborella trichopoda	36.27	2.00e-75	275.00
IUUC-Apl-003433	Anas platyrhynchos	68.93	0.00e+00	708.00
IUUC-Aca-005347	Anolis carolinensis	65.43	0.00e+00	697.00
IUUC-Aly-006565	Arabidopsis lyrata	32.97	7.00e-54	203.00
IUUC-Ath-007536	Arabidopsis thaliana	33.04	3.00e-54	204.00
IUUC-Ago-007811	Ashbya gossypii	27.64	4.00e-41	160.00
IUUC-Acl-008124	Aspergillus clavatus	29.82	3.00e-51	194.00
IUUC-Afl-008464	Aspergillus flavus	29.61	1.00e-46	179.00
IUUC-Afu-008912	Aspergillus fumigatus	28.14	1.00e-47	182.00
IUUC-Ani-009168	Aspergillus nidulans	31.76	8.00e-49	186.00
IUUC-Ang-009694	Aspergillus niger	28.77	4.00e-46	177.00
IUUC-Ate-010382	Aspergillus terreus	28.64	9.00e-46	176.00
IUUC-Ame-011253	Astyanax mexicanus	65.96	0.00e+00	635.00
IUUC-Bgr-012150	Blumeria graminis	30.32	1.00e-44	172.00
IUUC-Bta-013303	Bos taurus	70.33	0.00e+00	724.00
IUUC-Bci-013604	Botrytis cinerea	32.98	5.00e-53	200.00
IUUC-Bdi-014171	Brachypodium distachyon	32.70	1.00e-56	212.00
IUUC-Bol-016509	Brassica oleracea	34.67	9.00e-58	216.00
IUUC-Bra-016962	Brassica rapa	33.19	6.00e-57	213.00
IUUC-Cja-019283	Callithrix jacchus	72.07	0.00e+00	647.00
IUUC-Cfa-021239	Canis familiaris	71.55	0.00e+00	721.00
IUUC-Cpo-022354	Cavia porcellus	69.71	0.00e+00	715.00
IUUC-Csa-023145	Chlorocebus sabaeus	69.92	0.00e+00	721.00
IUUC-Cho-024938	Choloepus hoffmanni	61.21	8.00e-50	189.00
IUUC-Cin-025109	Ciona intestinalis	51.18	1.00e-97	348.00
IUUC-Csv-026214	Ciona savignyi	52.52	4.00e-142	496.00
IUUC-Cgl-026457	Colletotrichum gloeosporioides	31.40	3.00e-51	194.00
IUUC-Cne-027085	Cryptococcus neoformans	30.13	1.00e-45	176.00
IUUC-Dre-027433	Danio rerio	70.85	0.00e+00	704.00
IUUC-Dno-030095	Dasypus novemcinctus	70.70	0.00e+00	715.00
IUUC-Dse-031415	Dothistroma septosporum	27.41	6.00e-49	187.00
IUUC-Dme-032074	Drosophila melanogaster	57.51	6.00e-74	270.00
IUUC-Ete-033175	Echinops telfairi	57.66	2.00e-138	484.00
IUUC-Eca-033736	Equus caballus	71.13	0.00e+00	717.00
IUUC-Fca-035861	Felis catus	71.82	0.00e+00	724.00
IUUC-Fal-037645	Ficedula albicollis	68.83	0.00e+00	694.00
IUUC-Fox-038046	Fusarium oxysporum	30.24	3.00e-48	184.00
IUUC-Fso-038321	Fusarium solani	32.43	4.00e-49	187.00
IUUC-Ggr-040044	Gaeumannomyces graminis	32.37	2.00e-51	194.00
IUUC-Gga-040624	Gallus gallus	67.61	0.00e+00	709.00
IUUC-Gac-042197	Gasterosteus aculeatus	64.43	0.00e+00	653.00
IUUC-Gma-042897	Glycine max	31.35	4.00e-62	230.00
IUUC-Ggo-044409	Gorilla gorilla	70.12	0.00e+00	723.00
IUUC-Hsa-046521	Homo sapiens	70.12	0.00e+00	723.00
IUUC-Hvu-047739	Hordeum vulgare	33.07	2.00e-49	187.00
IUUC-Itr-048375	Ictidomys tridecemlineatus	70.33	0.00e+00	722.00
IUUC-Kpa-049135	Komagataella pastoris	32.83	7.00e-58	216.00
IUUC-Lch-050537	Latimeria chalumnae	70.12	0.00e+00	723.00
IUUC-Lpe-050969	Leersia perrieri	34.14	2.00e-54	204.00
IUUC-Loc-052765	Lepisosteus oculatus	66.34	0.00e+00	691.00
IUUC-Lma-053105	Leptosphaeria maculans	31.85	4.00e-55	207.00
IUUC-Laf-053571	Loxodonta africana	71.55	0.00e+00	721.00
IUUC-Mcc-055166	Macaca mulatta	69.92	0.00e+00	721.00
IUUC-Mor-057103	Magnaporthe oryzae	31.38	6.00e-52	196.00
IUUC-Mpo-057621	Magnaporthe poae	31.24	5.00e-51	193.00
IUUC-Mtr-057769	Medicago truncatula	32.23	7.00e-64	236.00
IUUC-Mla-059185	Melampsora laricipopulina	26.17	2.00e-27	115.00
IUUC-Mga-059709	Meleagris gallopavo	68.93	0.00e+00	708.00
IUUC-Mvi-060530	Microbotryum violaceum	30.47	3.00e-43	167.00
IUUC-Mmr-060988	Microcebus murinus	70.12	0.00e+00	722.00
IUUC-Mdo-063065	Monodelphis domestica	69.92	0.00e+00	721.00
IUUC-Mmu-063829	Mus musculus	69.71	0.00e+00	716.00
IUUC-Mac-065419	Musa acuminata	35.26	3.00e-55	207.00
IUUC-Mpu-066687	Mustela putorius furo	70.39	0.00e+00	717.00
IUUC-Mlu-067330	Myotis lucifugus	65.44	0.00e+00	650.00
IUUC-Nfi-068423	Neosartorya fischeri	28.29	2.00e-48	185.00
IUUC-Ncr-068809	Neurospora crassa	30.30	4.00e-50	191.00
IUUC-Nle-069261	Nomascus leucogenys	66.39	0.00e+00	670.00
IUUC-Opr-070469	Ochotona princeps	57.18	3.00e-136	476.00
IUUC-Ont-071961	Oreochromis niloticus	67.01	0.00e+00	680.00
IUUC-Oan-073565	Ornithorhynchus anatinus	64.85	0.00e+00	683.00
IUUC-Ocu-074435	Oryctolagus cuniculus	69.30	0.00e+00	688.00
IUUC-Oba-075688	Oryza barthii	33.12	7.00e-54	203.00
IUUC-Obr-076652	Oryza brachyantha	35.94	1.00e-53	202.00
IUUC-Ogl-077910	Oryza glaberrima	33.12	9.00e-57	213.00
IUUC-Ogu-078479	Oryza glumaepatula	33.12	8.00e-57	213.00
IUUC-Oin-079697	Oryza indica	35.28	2.00e-54	205.00
IUUC-Ome-081706	Oryza meridionalis	32.61	2.00e-56	212.00
IUUC-Oni-083070	Oryza nivara	33.12	1.00e-56	212.00
IUUC-Opu-083605	Oryza punctata	34.23	1.00e-46	178.00
IUUC-Oru-084522	Oryza rufipogon	33.12	9.00e-57	213.00
IUUC-Osa-085351	Oryza sativa	35.35	4.00e-55	207.00
IUUC-Ola-086743	Oryzias latipes	69.80	2.00e-166	576.00
IUUC-Olu-087695	Ostreococcus lucimarinus	29.19	5.00e-40	156.00
IUUC-Oga-089131	Otolemur garnettii	67.67	0.00e+00	707.00
IUUC-Oar-089319	Ovis aries	71.70	0.00e+00	721.00
IUUC-Ptr-090783	Pan troglodytes	71.55	0.00e+00	721.00
IUUC-Pan-092927	Papio anubis	69.92	0.00e+00	721.00
IUUC-Psi-093670	Pelodiscus sinensis	68.87	0.00e+00	706.00
IUUC-Pno-095141	Phaeosphaeria nodorum	30.41	3.00e-43	168.00
IUUC-Ppa-095413	Physcomitrella patens	38.33	9.00e-63	233.00
IUUC-Pfo-096462	Poecilia formosa	69.48	0.00e+00	703.00
IUUC-Pab-097612	Pongo abelii	69.92	0.00e+00	721.00
IUUC-Pop-099558	Populus trichocarpa	34.42	6.00e-68	250.00
IUUC-Pca-100329	Procavia capensis	65.64	0.00e+00	653.00
IUUC-Ppe-102020	Prunus persica	33.95	9.00e-69	253.00
IUUC-Pva-102721	Pteropus vampyrus	61.35	6.00e-173	598.00
IUUC-Pgr-103657	Puccinia graminis	33.62	4.00e-27	114.00
IUUC-Pte-104340	Pyrenophora teres	30.51	3.00e-46	177.00
IUUC-Pyt-104782	Pyrenophora triticirepentis	32.07	7.00e-54	203.00
IUUC-Rno-105247	Rattus norvegicus	69.71	0.00e+00	718.00
IUUC-Sce-106247	Saccharomyces cerevisiae	26.94	5.00e-40	157.00
IUUC-Sja-107656	Schizosaccharomyces japonicus	32.62	2.00e-54	204.00
IUUC-Spo-108226	Schizosaccharomyces pombe	29.89	2.00e-46	178.00
IUUC-Ssl-108531	Sclerotinia sclerotiorum	31.36	6.00e-49	186.00
IUUC-Smo-109310	Selaginella moellendorffii	33.58	3.00e-71	261.00
IUUC-Sit-109716	Setaria italica	33.13	4.00e-60	224.00
IUUC-Sly-111077	Solanum lycopersicum	36.36	5.00e-61	227.00
IUUC-Stu-112203	Solanum tuberosum	34.73	5.00e-59	220.00
IUUC-Sar-113174	Sorex araneus	60.91	3.00e-162	563.00
IUUC-Sbi-114205	Sorghum bicolor	32.09	7.00e-59	220.00
IUUC-Ssc-115315	Sus scrofa	64.13	0.00e+00	651.00
IUUC-Tgu-116938	Taeniopygia guttata	71.13	0.00e+00	717.00
IUUC-Tru-117622	Takifugu rubripes	67.81	0.00e+00	703.00
IUUC-Tsy-119431	Tarsius syrichta	61.28	4.00e-170	589.00
IUUC-Tni-120119	Tetraodon nigroviridis	69.77	0.00e+00	708.00
IUUC-Tca-121154	Theobroma cacao	35.96	5.00e-71	260.00
IUUC-Tre-122139	Trichoderma reesei	32.58	4.00e-51	193.00
IUUC-Tvi-122599	Trichoderma virens	32.01	8.00e-53	199.00
IUUC-Tae-125608	Triticum aestivum	33.05	2.00e-64	238.00
IUUC-Tur-126423	Triticum urartu	26.65	1.00e-29	124.00
IUUC-Tme-127115	Tuber melanosporum	34.25	1.00e-64	239.00
IUUC-Ttr-129006	Tursiops truncatus	64.72	0.00e+00	629.00
IUUC-Uma-129455	Ustilago maydis	34.50	6.00e-33	134.00
IUUC-Vda-129829	Verticillium dahliae	34.57	4.00e-33	133.00
IUUC-Vvi-131477	Vitis vinifera	34.55	2.00e-57	214.00
IUUC-Xtr-132444	Xenopus tropicalis	67.81	0.00e+00	710.00
IUUC-Xma-133514	Xiphophorus maculatus	69.71	0.00e+00	711.00
IUUC-Zma-134945	Zea mays	32.28	3.00e-56	211.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence