iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Nle-069687

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01130038

Gene Name

UBE3C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000000246.1	ENSNLET00000000345.1	ENSNLEP00000000321.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.50e-105	353.2	723	1060

Active Site

Position(s)	Description	Evidence
1028	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqd 84
            dlkkr++v++++     E+g+d gG++refl++l+k  +np+ g+f++++++    +p+ ++ + +    ++++flGr+lgkal++
   Q: 723  PDLKKRIRVHLLNahgldEAGIDGGGIFREFLNELLKSGFNPNQGFFKTTNEGLLYPNPAAQMLVGD-SFARHYYFLGRMLGKALYE 808
           689**********99**9************************************9999999999965.999**************** PP
   S: 85   grlldlplsksfyklllgk..klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneN 169
           + l++lp++ +f+++llg+  ++++++l+++dpe+yk+l ++k++ e+d+eelgl++t+   ++ lge++++eLk gG++ipVt +N
   Q: 809  NMLVELPFAGFFLSKLLGTsaDVDIHHLASLDPEVYKNLLFLKSY-EDDVEELGLNFTV--VNNDLGEAQVVELKFGGKDIPVTSAN 892
           ******************9666889********************.6788887666665..5889********************** PP
   S: 170  keeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevlee 255
           + +Y++lv++yrl+++i++++ afr+G+ +v++le+l++F+++e+++li+G    i++edlk++t+y ggy++d+p+i+ Fw+v+e+
   Q: 893  RIAYIHLVADYRLNRQIRQHCLAFRQGLANVVSLEWLRMFDQQEIQVLISGAqVPISLEDLKSFTNYSGGYSADHPVIKVFWRVVEG 979
           ****************************************************899******************************** PP
   S: 256  fsseerkafLqFvTgssrlPlgGfaelkprlfvirkdasd.drlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
           f++ee++++L+FvT++sr Pl Gf+el p  f+i++ +sd +rlP+++TC+n+LkLPe+  ++ l++kLlyAie ++gFels
   Q: 980  FTDEEKRKLLKFVTSCSRPPLLGFKELYPA-FCIHNGGSDlERLPTASTCMNLLKLPEFYDETLLRSKLLYAIECAAGFELS 1060
           ****************************88.*****99999**************************************985 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

EEKASLLHRT QEERRKREEE RRRLKNAIII QSFIRGYRDR KQQYSIQRSA FDRCATLSQS 60
GGAFPIANGP NLTLLVRQLL FFYKQSEDSK RLIWLYQNLI KHSALFVKQL DGSERLTCLF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTAGGAGGAA AAGGCTTCTC TTTTACATCG TACTCAGGAA GAAAGAAGAA AGAGAGAGGT 60
AAAAACAGTT TTGTAATACT CCGTAGATAA GCATTTTTTC TACAGCATTT AAACACGCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT

SMART

SM00119--HECTc
SM00015--IQ

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity
GO:0000209--P:protein polyubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001355	Ailuropoda melanoleuca	94.16	0.00e+00	1942.00
IUUC-Apl-003731	Anas platyrhynchos	90.03	0.00e+00	1878.00
IUUC-Aca-005248	Anolis carolinensis	88.88	0.00e+00	1871.00
IUUC-Aly-005768	Arabidopsis lyrata	34.88	1.00e-106	381.00
IUUC-Ago-007748	Ashbya gossypii	41.45	4.00e-76	279.00
IUUC-Acl-008158	Aspergillus clavatus	33.85	2.00e-76	280.00
IUUC-Afl-008398	Aspergillus flavus	33.33	3.00e-76	280.00
IUUC-Afu-008937	Aspergillus fumigatus	38.00	4.00e-77	283.00
IUUC-Ani-009252	Aspergillus nidulans	37.31	1.00e-78	288.00
IUUC-Ang-009773	Aspergillus niger	37.10	4.00e-75	276.00
IUUC-Aor-009940	Aspergillus oryzae	33.33	3.00e-76	280.00
IUUC-Ate-010395	Aspergillus terreus	38.17	4.00e-75	276.00
IUUC-Ame-010769	Astyanax mexicanus	62.94	0.00e+00	1051.00
IUUC-Bgr-012269	Blumeria graminis	37.34	2.00e-73	269.00
IUUC-Bta-012841	Bos taurus	92.85	0.00e+00	1920.00
IUUC-Bci-013743	Botrytis cinerea	37.69	1.00e-80	295.00
IUUC-Bol-015390	Brassica oleracea	45.34	9.00e-99	355.00
IUUC-Bra-016853	Brassica rapa	34.72	2.00e-105	377.00
IUUC-Cel-018638	Caenorhabditis elegans	40.19	1.00e-90	328.00
IUUC-Cja-019743	Callithrix jacchus	97.45	0.00e+00	1985.00
IUUC-Cfa-021031	Canis familiaris	94.65	0.00e+00	1952.00
IUUC-Cpo-022401	Cavia porcellus	93.12	0.00e+00	1929.00
IUUC-Cre-022725	Chlamydomonas reinhardtii	43.99	2.00e-84	305.00
IUUC-Csa-024107	Chlorocebus sabaeus	99.06	0.00e+00	2024.00
IUUC-Cho-024750	Choloepus hoffmanni	82.29	0.00e+00	795.00
IUUC-Cin-025432	Ciona intestinalis	44.39	1.00e-94	339.00
IUUC-Cgl-026559	Colletotrichum gloeosporioides	34.03	8.00e-88	318.00
IUUC-Cne-026841	Cryptococcus neoformans	36.32	4.00e-93	336.00
IUUC-Cme-027265	Cyanidioschyzon merolae	48.00	1.00e-102	367.00
IUUC-Dre-028196	Danio rerio	76.81	0.00e+00	1555.00
IUUC-Dno-029024	Dasypus novemcinctus	95.76	0.00e+00	1983.00
IUUC-Dor-030483	Dipodomys ordii	90.86	0.00e+00	682.00
IUUC-Dse-031416	Dothistroma septosporum	33.73	2.00e-77	284.00
IUUC-Dme-031946	Drosophila melanogaster	36.76	0.00e+00	647.00
IUUC-Ete-032240	Echinops telfairi	84.58	5.00e-174	605.00
IUUC-Eca-033828	Equus caballus	95.01	0.00e+00	1981.00
IUUC-Eeu-034604	Erinaceus europaeus	85.77	1.00e-126	447.00
IUUC-Fca-035907	Felis catus	93.79	0.00e+00	1954.00
IUUC-Fal-037389	Ficedula albicollis	90.40	0.00e+00	1907.00
IUUC-Fox-037788	Fusarium oxysporum	35.69	1.00e-89	324.00
IUUC-Fso-038088	Fusarium solani	35.47	2.00e-87	317.00
IUUC-Gmo-039254	Gadus morhua	65.47	0.00e+00	1184.00
IUUC-Ggr-039941	Gaeumannomyces graminis	34.27	6.00e-83	302.00
IUUC-Gga-040310	Gallus gallus	90.02	0.00e+00	1897.00
IUUC-Gac-042054	Gasterosteus aculeatus	68.71	0.00e+00	1252.00
IUUC-Ggo-045031	Gorilla gorilla	99.25	0.00e+00	2029.00
IUUC-Hsa-045880	Homo sapiens	99.34	0.00e+00	2030.00
IUUC-Itr-048555	Ictidomys tridecemlineatus	91.21	0.00e+00	717.00
IUUC-Kpa-049307	Komagataella pastoris	36.75	3.00e-65	243.00
IUUC-Lch-050403	Latimeria chalumnae	81.24	0.00e+00	1635.00
IUUC-Loc-052218	Lepisosteus oculatus	80.43	0.00e+00	1651.00
IUUC-Lma-053096	Leptosphaeria maculans	37.72	2.00e-78	287.00
IUUC-Laf-054162	Loxodonta africana	91.21	0.00e+00	1709.00
IUUC-Mcc-055127	Macaca mulatta	98.96	0.00e+00	2021.00
IUUC-Meu-056187	Macropus eugenii	80.87	4.00e-102	365.00
IUUC-Mor-057021	Magnaporthe oryzae	35.19	2.00e-78	287.00
IUUC-Mpo-057570	Magnaporthe poae	36.03	4.00e-75	276.00
IUUC-Mla-059124	Melampsora laricipopulina	47.72	9.00e-101	360.00
IUUC-Mga-059581	Meleagris gallopavo	90.11	0.00e+00	1900.00
IUUC-Mvi-060445	Microbotryum violaceum	37.44	5.00e-104	372.00
IUUC-Mmr-061360	Microcebus murinus	92.24	0.00e+00	1887.00
IUUC-Mdo-062194	Monodelphis domestica	90.58	0.00e+00	1909.00
IUUC-Mmu-064189	Mus musculus	92.93	0.00e+00	1960.00
IUUC-Mac-065275	Musa acuminata	48.41	1.00e-106	380.00
IUUC-Mpu-066439	Mustela putorius furo	93.41	0.00e+00	1931.00
IUUC-Mlu-068228	Myotis lucifugus	90.31	0.00e+00	1903.00
IUUC-Nfi-068280	Neosartorya fischeri	38.00	3.00e-77	283.00
IUUC-Ncr-068869	Neurospora crassa	35.33	1.00e-80	295.00
IUUC-Opr-070592	Ochotona princeps	78.57	4.00e-128	452.00
IUUC-Ont-071836	Oreochromis niloticus	77.47	0.00e+00	1602.00
IUUC-Oan-072800	Ornithorhynchus anatinus	90.68	0.00e+00	1904.00
IUUC-Ocu-074587	Oryctolagus cuniculus	96.98	0.00e+00	2004.00
IUUC-Ola-087209	Oryzias latipes	77.38	0.00e+00	1578.00
IUUC-Olu-087699	Ostreococcus lucimarinus	42.59	3.00e-86	311.00
IUUC-Oga-088776	Otolemur garnettii	90.86	0.00e+00	1794.00
IUUC-Oar-089441	Ovis aries	91.82	0.00e+00	1898.00
IUUC-Ptr-091273	Pan troglodytes	99.25	0.00e+00	2028.00
IUUC-Pan-091981	Papio anubis	99.06	0.00e+00	2026.00
IUUC-Psi-093203	Pelodiscus sinensis	88.65	0.00e+00	1626.00
IUUC-Pma-094738	Petromyzon marinus	64.34	0.00e+00	1281.00
IUUC-Pno-095132	Phaeosphaeria nodorum	29.07	4.00e-58	219.00
IUUC-Ppa-095682	Physcomitrella patens	36.93	7.00e-110	391.00
IUUC-Pfo-097511	Poecilia formosa	77.29	0.00e+00	1612.00
IUUC-Pab-098634	Pongo abelii	96.14	0.00e+00	1945.00
IUUC-Pop-098928	Populus trichocarpa	34.59	5.00e-98	352.00
IUUC-Pca-100987	Procavia capensis	98.96	0.00e+00	795.00
IUUC-Pva-103034	Pteropus vampyrus	89.08	0.00e+00	1825.00
IUUC-Pgr-103513	Puccinia graminis	39.00	5.00e-105	375.00
IUUC-Ptt-103967	Puccinia triticina	41.85	6.00e-93	335.00
IUUC-Pte-104105	Pyrenophora teres	33.68	1.00e-79	291.00
IUUC-Pyt-104449	Pyrenophora triticirepentis	36.85	2.00e-76	281.00
IUUC-Rno-105380	Rattus norvegicus	92.34	0.00e+00	1691.00
IUUC-Sce-106446	Saccharomyces cerevisiae	40.05	3.00e-67	249.00
IUUC-Sha-107108	Sarcophilus harrisii	84.77	0.00e+00	1763.00
IUUC-Sja-107889	Schizosaccharomyces japonicus	42.02	4.00e-93	336.00
IUUC-Spo-108097	Schizosaccharomyces pombe	41.81	5.00e-92	332.00
IUUC-Ssl-108520	Sclerotinia sclerotiorum	30.35	4.00e-81	296.00
IUUC-Sar-113687	Sorex araneus	81.62	0.00e+00	902.00
IUUC-Sre-115038	Sporisorium reilianum	43.73	4.00e-96	346.00
IUUC-Ssc-116168	Sus scrofa	87.69	0.00e+00	769.00
IUUC-Tgu-116729	Taeniopygia guttata	90.12	0.00e+00	1899.00
IUUC-Tru-118068	Takifugu rubripes	76.44	0.00e+00	1569.00
IUUC-Tsy-118942	Tarsius syrichta	97.09	0.00e+00	719.00
IUUC-Tni-120732	Tetraodon nigroviridis	75.49	0.00e+00	1513.00
IUUC-Tre-121892	Trichoderma reesei	36.76	2.00e-86	314.00
IUUC-Tvi-122354	Trichoderma virens	34.97	5.00e-87	316.00
IUUC-Tme-127102	Tuber melanosporum	35.64	2.00e-90	327.00
IUUC-Tbe-127351	Tupaia belangeri	82.44	0.00e+00	1543.00
IUUC-Ttr-129061	Tursiops truncatus	90.49	0.00e+00	1861.00
IUUC-Uma-129343	Ustilago maydis	43.73	6.00e-97	349.00
IUUC-Vda-129748	Verticillium dahliae	34.27	2.00e-82	300.00
IUUC-Xtr-132094	Xenopus tropicalis	85.34	0.00e+00	1743.00
IUUC-Xma-133923	Xiphophorus maculatus	77.38	0.00e+00	1612.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence