iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-048818

Ensembl Protein ID

ENSSTOP00000017421.1

UniProt Accession

I3MZ75; I3MZ75_ICTTR

Genbank Protein ID

ENSSTOP00000017421

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01043460

Gene Name

TOPORS

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000025870.1	ENSSTOT00000027673.1	ENSSTOP00000017421.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.20e-09	37.2	102	141

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iCl++f++  ++ +C H f++ C+q w      s++++ CPlC+
   Q: 102  CPICLDRFDNVSYLDRCLHKFCFRCVQEW------SKNKAECPLCK 141
           **********999999*************......**********7 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

GSQQPPGSPL SREEGEAPPP TPAPEGRRRS RRVRLRGSCR HRPSLLGRGE LASSAAAGPA 60
PASSEIMASA AKEFKMDNFS PKAGTSKLQQ TVPADASPDS KCPICLDRFD NVSYLDRCLH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGTCGCAG CAGCCGCCAG GGTCTCCGCT GTCTCGCGAG GAGGGTGAAG CGCCCCCGCC 60
TACTCCCGCA CCGGAGGGTA GGCGGAGAAG TCGCCGGGTA CGCCTTCGTG GATCTTGCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005814--C:centriole
GO:0036064--C:ciliary basal body
GO:0000930--C:gamma-tubulin complex
GO:0016607--C:nuclear speck
GO:0032391--C:photoreceptor connecting cilium
GO:0016605--C:PML body
GO:0000922--C:spindle pole
GO:0000151--C:ubiquitin ligase complex
GO:0003823--F:antigen binding
GO:0003677--F:DNA binding
GO:0019789--F:SUMO transferase activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0042771--P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0051457--P:maintenance of protein location in nucleus
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
GO:0006513--P:protein monoubiquitination
GO:0042127--P:regulation of cell proliferation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000940	Aegilops tauschii	36.76	2.00e-09	55.80
IUUC-Aml-002240	Ailuropoda melanoleuca	90.14	0.00e+00	899.00
IUUC-Atr-002964	Amborella trichopoda	30.16	4.00e-13	67.80
IUUC-Apl-003666	Anas platyrhynchos	55.23	6.00e-139	488.00
IUUC-Aca-005305	Anolis carolinensis	62.39	1.00e-148	520.00
IUUC-Aly-005926	Arabidopsis lyrata	37.23	4.00e-11	61.60
IUUC-Ath-007668	Arabidopsis thaliana	40.00	7.00e-08	50.80
IUUC-Ame-011109	Astyanax mexicanus	53.16	7.00e-114	404.00
IUUC-Bta-012637	Bos taurus	90.54	0.00e+00	894.00
IUUC-Bdi-014270	Brachypodium distachyon	40.00	2.00e-11	62.80
IUUC-Bol-015307	Brassica oleracea	32.98	3.00e-10	58.90
IUUC-Bra-017073	Brassica rapa	44.90	2.00e-08	52.00
IUUC-Cja-019105	Callithrix jacchus	92.86	0.00e+00	981.00
IUUC-Cfa-021203	Canis familiaris	90.82	0.00e+00	897.00
IUUC-Cpo-022335	Cavia porcellus	86.50	0.00e+00	856.00
IUUC-Csa-023870	Chlorocebus sabaeus	92.02	0.00e+00	949.00
IUUC-Cho-024870	Choloepus hoffmanni	90.68	0.00e+00	867.00
IUUC-Cne-026788	Cryptococcus neoformans	33.85	3.00e-07	50.10
IUUC-Dre-027535	Danio rerio	50.54	3.00e-121	429.00
IUUC-Dno-028963	Dasypus novemcinctus	91.67	0.00e+00	862.00
IUUC-Dor-030239	Dipodomys ordii	91.00	0.00e+00	802.00
IUUC-Dme-031941	Drosophila melanogaster	33.33	1.00e-38	154.00
IUUC-Ete-032300	Echinops telfairi	82.45	0.00e+00	1109.00
IUUC-Eca-033690	Equus caballus	92.57	0.00e+00	892.00
IUUC-Eeu-035257	Erinaceus europaeus	86.93	0.00e+00	859.00
IUUC-Fca-036383	Felis catus	90.07	0.00e+00	896.00
IUUC-Fal-037209	Ficedula albicollis	62.31	4.00e-158	551.00
IUUC-Gmo-039416	Gadus morhua	52.84	7.00e-118	417.00
IUUC-Gga-041267	Gallus gallus	71.86	4.00e-169	588.00
IUUC-Gac-042227	Gasterosteus aculeatus	51.37	1.00e-114	406.00
IUUC-Gma-042777	Glycine max	32.61	3.00e-09	55.50
IUUC-Ggo-044445	Gorilla gorilla	92.02	0.00e+00	966.00
IUUC-Hsa-045844	Homo sapiens	92.19	0.00e+00	968.00
IUUC-Hvu-047531	Hordeum vulgare	46.00	8.00e-11	57.80
IUUC-Lch-050031	Latimeria chalumnae	64.82	2.00e-167	582.00
IUUC-Lpe-051274	Leersia perrieri	37.74	9.00e-09	53.50
IUUC-Loc-052944	Lepisosteus oculatus	56.92	3.00e-142	498.00
IUUC-Laf-053820	Loxodonta africana	92.04	0.00e+00	854.00
IUUC-Mcc-054800	Macaca mulatta	92.02	0.00e+00	947.00
IUUC-Meu-056806	Macropus eugenii	72.18	0.00e+00	635.00
IUUC-Mtr-058378	Medicago truncatula	34.58	7.00e-13	67.40
IUUC-Mla-059017	Melampsora laricipopulina	36.07	3.00e-09	55.80
IUUC-Mvi-060417	Microbotryum violaceum	24.83	9.00e-17	82.00
IUUC-Mmr-061481	Microcebus murinus	93.24	0.00e+00	911.00
IUUC-Mdo-062219	Monodelphis domestica	80.65	6.00e-108	384.00
IUUC-Mmu-064138	Mus musculus	88.89	0.00e+00	820.00
IUUC-Mlu-067088	Myotis lucifugus	90.15	0.00e+00	901.00
IUUC-Nle-069862	Nomascus leucogenys	92.51	0.00e+00	963.00
IUUC-Opr-071076	Ochotona princeps	92.28	0.00e+00	801.00
IUUC-Ont-072225	Oreochromis niloticus	51.70	1.00e-112	400.00
IUUC-Oan-073069	Ornithorhynchus anatinus	66.13	1.00e-155	542.00
IUUC-Ocu-074826	Oryctolagus cuniculus	91.85	0.00e+00	937.00
IUUC-Oba-075429	Oryza barthii	37.68	1.00e-10	60.10
IUUC-Obr-076084	Oryza brachyantha	36.23	3.00e-10	58.50
IUUC-Ogl-077444	Oryza glaberrima	37.68	1.00e-10	60.10
IUUC-Ogu-078603	Oryza glumaepatula	37.68	1.00e-10	60.10
IUUC-Oin-079777	Oryza indica	37.68	1.00e-10	59.70
IUUC-Oni-082396	Oryza nivara	37.68	1.00e-10	60.10
IUUC-Opu-083698	Oryza punctata	36.62	6.00e-10	57.80
IUUC-Oru-084305	Oryza rufipogon	37.68	1.00e-10	60.10
IUUC-Ola-087377	Oryzias latipes	53.95	2.00e-108	385.00
IUUC-Oga-088059	Otolemur garnettii	89.46	0.00e+00	901.00
IUUC-Oar-089592	Ovis aries	89.78	0.00e+00	885.00
IUUC-Ptr-091233	Pan troglodytes	92.02	0.00e+00	966.00
IUUC-Pan-092743	Papio anubis	92.02	0.00e+00	948.00
IUUC-Psi-093669	Pelodiscus sinensis	60.62	0.00e+00	832.00
IUUC-Ppa-095668	Physcomitrella patens	26.11	3.00e-22	99.40
IUUC-Pfo-096706	Poecilia formosa	53.33	2.00e-105	376.00
IUUC-Pop-099119	Populus trichocarpa	23.55	2.00e-12	66.20
IUUC-Pca-100967	Procavia capensis	89.29	0.00e+00	794.00
IUUC-Ppe-101922	Prunus persica	35.06	7.00e-09	53.90
IUUC-Pva-102982	Pteropus vampyrus	93.71	0.00e+00	920.00
IUUC-Pgr-103551	Puccinia graminis	38.46	7.00e-09	53.90
IUUC-Ptt-103977	Puccinia triticina	33.33	5.00e-08	50.80
IUUC-Rno-105730	Rattus norvegicus	88.24	0.00e+00	778.00
IUUC-Sha-106588	Sarcophilus harrisii	68.77	2.00e-178	619.00
IUUC-Sja-107735	Schizosaccharomyces japonicus	35.38	2.00e-07	49.70
IUUC-Smo-109039	Selaginella moellendorffii	25.08	7.00e-20	91.30
IUUC-Sly-111835	Solanum lycopersicum	42.37	1.00e-08	55.50
IUUC-Stu-112898	Solanum tuberosum	42.37	1.00e-08	55.50
IUUC-Sar-113622	Sorex araneus	88.40	3.00e-159	555.00
IUUC-Sre-115041	Sporisorium reilianum	37.84	1.00e-09	57.00
IUUC-Ssc-115244	Sus scrofa	92.70	0.00e+00	862.00
IUUC-Tgu-117180	Taeniopygia guttata	63.44	2.00e-166	579.00
IUUC-Tru-118393	Takifugu rubripes	52.53	1.00e-117	417.00
IUUC-Tsy-119408	Tarsius syrichta	93.53	0.00e+00	933.00
IUUC-Tni-120664	Tetraodon nigroviridis	55.16	1.00e-119	423.00
IUUC-Tca-121712	Theobroma cacao	27.85	6.00e-17	81.30
IUUC-Tae-122787	Triticum aestivum	38.57	1.00e-10	60.10
IUUC-Tbe-127301	Tupaia belangeri	84.55	0.00e+00	808.00
IUUC-Ttr-128204	Tursiops truncatus	92.12	0.00e+00	913.00
IUUC-Uma-129420	Ustilago maydis	43.06	8.00e-10	57.40
IUUC-Vpa-130297	Vicugna pacos	92.32	0.00e+00	886.00
IUUC-Vvi-131157	Vitis vinifera	26.91	2.00e-17	82.40
IUUC-Xtr-132845	Xenopus tropicalis	67.67	8.00e-171	593.00
IUUC-Xma-133439	Xiphophorus maculatus	53.29	2.00e-107	383.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence