iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
AREsite	miRTarBase	microRNA	TRANSFAC
RepTar	RAID2
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	3.50e-09	37.7	539	586
E3 activity/RING/RING	1.80e-09	39.1	543	581

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplte 52
           ++f C++ + l+ +Pv++p+G+++ ++++e++l++    cP+++++l+e
   Q: 539  SDFECSLCMRLFFEPVTTPCGHSFCKNCLERCLDHAPY-CPLCKESLKE 586
           68***********************************9.*******986 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++C+  f++ p+++pCgH f+++Cl++          + +CPlC+
   Q: 543  CSLCMRLFFE-PVTTPCGHSFCKNCLERC------LDHAPYCPLCK 581
           **********.9**************999......9*********6 PP

Organism

Mus musculus

Protein Sequence
(Fasta)

MSGGRAQKPR PAPLRLAKPR PSSVGPAPRG SPGARRPAMS ARHAPLLAGR VRSRAPRRFP 60
DRGGGRRRQS SPVRAMSSPA VARASPGGNR EASGGPRSRN GPWEVGGGGE RLERAGAESG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGCCGGCCA GCTCTGGTGA ACTAGGAGGC CGGCCGCATG TCGGGAGGCC GGGCGCAGAA 60
GCCAAGGCCC GCCCCGCTCC GCCTCGCTAA GCCTCGCCCC TCCTCTGTAG GCCCCGCCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003111--Lon_substr-bd
IPR015947--PUA-like_domain
IPR013026--TPR-contain_dom
IPR011990--TPR-like_helical_dom
IPR019734--TPR_repeat
IPR027370--Znf-RING_LisH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51787--LON_N
PS50293--TPR_REGION
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02190--LON_substr_bdg
PF13445--zf-RING_UBOX

SMART

SM00464--LON
SM00184--RING
SM00028--TPR

Gene Ontology

GO:0008270--F:zinc ion binding

KEGG

mmu:244421

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001989	Ailuropoda melanoleuca	87.45	0.00e+00	945.00
IUUC-Atr-002972	Amborella trichopoda	41.83	3.00e-43	169.00
IUUC-Apl-003309	Anas platyrhynchos	79.64	3.00e-180	624.00
IUUC-Aca-004288	Anolis carolinensis	63.62	0.00e+00	847.00
IUUC-Aly-005476	Arabidopsis lyrata	35.96	5.00e-40	159.00
IUUC-Ath-006654	Arabidopsis thaliana	36.33	1.00e-40	160.00
IUUC-Ang-009643	Aspergillus niger	30.08	7.00e-39	155.00
IUUC-Ate-010489	Aspergillus terreus	31.91	2.00e-38	153.00
IUUC-Ame-010716	Astyanax mexicanus	50.34	0.00e+00	656.00
IUUC-Bta-012903	Bos taurus	88.09	0.00e+00	1029.00
IUUC-Bdi-014333	Brachypodium distachyon	41.26	1.00e-42	167.00
IUUC-Bol-016150	Brassica oleracea	36.02	4.00e-41	162.00
IUUC-Bra-016716	Brassica rapa	34.55	2.00e-38	153.00
IUUC-Cel-018356	Caenorhabditis elegans	33.33	8.00e-10	56.20
IUUC-Cja-019312	Callithrix jacchus	88.14	0.00e+00	1109.00
IUUC-Cfa-020159	Canis familiaris	85.67	0.00e+00	1064.00
IUUC-Cpo-022528	Cavia porcellus	90.81	0.00e+00	962.00
IUUC-Cre-022730	Chlamydomonas reinhardtii	27.70	4.00e-08	52.00
IUUC-Csa-023361	Chlorocebus sabaeus	81.50	0.00e+00	1042.00
IUUC-Cho-024549	Choloepus hoffmanni	80.08	0.00e+00	800.00
IUUC-Cgl-026514	Colletotrichum gloeosporioides	31.38	6.00e-44	172.00
IUUC-Cme-027153	Cyanidioschyzon merolae	30.35	3.00e-28	119.00
IUUC-Dre-028195	Danio rerio	50.41	0.00e+00	657.00
IUUC-Dno-029284	Dasypus novemcinctus	88.58	0.00e+00	963.00
IUUC-Dor-031123	Dipodomys ordii	78.10	0.00e+00	699.00
IUUC-Ete-032455	Echinops telfairi	87.34	0.00e+00	719.00
IUUC-Eca-033248	Equus caballus	90.33	0.00e+00	718.00
IUUC-Eeu-034441	Erinaceus europaeus	86.30	0.00e+00	751.00
IUUC-Fca-035551	Felis catus	87.83	0.00e+00	967.00
IUUC-Fal-036731	Ficedula albicollis	74.67	0.00e+00	806.00
IUUC-Gmo-039315	Gadus morhua	47.35	2.00e-169	589.00
IUUC-Gga-040888	Gallus gallus	76.44	0.00e+00	654.00
IUUC-Gac-042121	Gasterosteus aculeatus	51.97	0.00e+00	657.00
IUUC-Ggo-044985	Gorilla gorilla	88.73	0.00e+00	991.00
IUUC-Hsa-046592	Homo sapiens	86.68	0.00e+00	1083.00
IUUC-Hvu-047145	Hordeum vulgare	40.65	8.00e-25	107.00
IUUC-Itr-048573	Ictidomys tridecemlineatus	92.19	0.00e+00	1068.00
IUUC-Lch-050404	Latimeria chalumnae	57.54	0.00e+00	749.00
IUUC-Laf-053431	Loxodonta africana	87.83	0.00e+00	952.00
IUUC-Mcc-055751	Macaca mulatta	86.77	0.00e+00	968.00
IUUC-Mor-056963	Magnaporthe oryzae	41.71	2.00e-41	164.00
IUUC-Mla-058946	Melampsora laricipopulina	34.59	2.00e-44	173.00
IUUC-Mvi-060228	Microbotryum violaceum	33.66	7.00e-46	179.00
IUUC-Mmr-061283	Microcebus murinus	87.65	0.00e+00	1102.00
IUUC-Mac-065566	Musa acuminata	37.66	4.00e-43	169.00
IUUC-Mpu-066537	Mustela putorius furo	84.82	0.00e+00	1085.00
IUUC-Mlu-067497	Myotis lucifugus	87.83	0.00e+00	959.00
IUUC-Nle-068971	Nomascus leucogenys	89.68	0.00e+00	949.00
IUUC-Opr-070791	Ochotona princeps	90.36	0.00e+00	874.00
IUUC-Ont-071548	Oreochromis niloticus	51.94	0.00e+00	671.00
IUUC-Oan-072747	Ornithorhynchus anatinus	80.55	0.00e+00	666.00
IUUC-Ocu-074928	Oryctolagus cuniculus	93.13	0.00e+00	750.00
IUUC-Oba-075239	Oryza barthii	40.69	7.00e-43	168.00
IUUC-Obr-076158	Oryza brachyantha	40.64	1.00e-44	174.00
IUUC-Ogu-078154	Oryza glumaepatula	41.18	2.00e-43	171.00
IUUC-Oin-079067	Oryza indica	40.69	4.00e-43	169.00
IUUC-Olo-080663	Oryza longistaminata	40.69	1.00e-42	167.00
IUUC-Oni-082119	Oryza nivara	40.69	5.00e-43	168.00
IUUC-Opu-083266	Oryza punctata	35.29	3.00e-31	129.00
IUUC-Oru-085190	Oryza rufipogon	40.69	1.00e-42	167.00
IUUC-Ola-086977	Oryzias latipes	51.98	0.00e+00	671.00
IUUC-Oga-088719	Otolemur garnettii	84.68	0.00e+00	1105.00
IUUC-Oar-089577	Ovis aries	88.06	0.00e+00	974.00
IUUC-Ptr-090711	Pan troglodytes	86.29	0.00e+00	1086.00
IUUC-Pan-092587	Papio anubis	81.24	0.00e+00	1064.00
IUUC-Psi-093128	Pelodiscus sinensis	72.82	0.00e+00	836.00
IUUC-Ppa-095498	Physcomitrella patens	29.59	1.00e-09	56.60
IUUC-Pfo-096474	Poecilia formosa	51.68	0.00e+00	666.00
IUUC-Pab-097800	Pongo abelii	86.34	0.00e+00	1038.00
IUUC-Pop-100044	Populus trichocarpa	34.62	2.00e-43	170.00
IUUC-Ppe-101621	Prunus persica	38.29	2.00e-36	147.00
IUUC-Rno-105718	Rattus norvegicus	94.82	0.00e+00	1086.00
IUUC-Sit-110495	Setaria italica	39.56	1.00e-42	167.00
IUUC-Sly-111396	Solanum lycopersicum	33.90	1.00e-41	164.00
IUUC-Sar-113220	Sorex araneus	85.06	0.00e+00	687.00
IUUC-Sbi-114779	Sorghum bicolor	38.07	7.00e-29	121.00
IUUC-Sre-114977	Sporisorium reilianum	32.20	2.00e-35	145.00
IUUC-Ssc-115733	Sus scrofa	82.99	0.00e+00	1105.00
IUUC-Tgu-117431	Taeniopygia guttata	70.32	0.00e+00	859.00
IUUC-Tru-118274	Takifugu rubripes	50.70	0.00e+00	627.00
IUUC-Tsy-119043	Tarsius syrichta	89.31	0.00e+00	951.00
IUUC-Tni-120766	Tetraodon nigroviridis	49.70	2.00e-171	595.00
IUUC-Tae-125900	Triticum aestivum	34.72	5.00e-45	175.00
IUUC-Tur-126297	Triticum urartu	40.24	4.00e-32	132.00
IUUC-Tme-127112	Tuber melanosporum	35.94	2.00e-46	179.00
IUUC-Tbe-127284	Tupaia belangeri	88.22	0.00e+00	737.00
IUUC-Vda-129721	Verticillium dahliae	27.88	4.00e-36	145.00
IUUC-Vpa-130408	Vicugna pacos	79.70	0.00e+00	832.00
IUUC-Xtr-132417	Xenopus tropicalis	57.78	0.00e+00	720.00
IUUC-Xma-134099	Xiphophorus maculatus	51.53	0.00e+00	664.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence