iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ata-000750

Ensembl Protein ID

EMT27481

UniProt Accession

M8CUJ9; M8CUJ9_AEGTA

Genbank Protein ID

EMT27481.1

Protein Name

E3 ubiquitin-protein ligase UPL3

Genbank Nucleotide ID

KD511159

Gene Name

F775_26384

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
F775_26384	EMT27481	EMT27481

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	5.60e-101	339.0	1392	1782

Active Site

Position(s)	Description	Evidence
1750	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknp...........................ehlklFefl 74
           s++k++leve+ gE g++l G+t+ef++lls++lq+  lgl++ ++++ e  +++++s  ++                            ++ ++F+++
   Q: 1392 SNQKAVLEVEYFGEVGTGL-GPTLEFYTLLSHDLQRVGLGLWRSDSDSLEAKKVDSHSPADSRnliqaplglfprpwppstassegskffKVVEYFRLV 1489
           57899**************.************************9998888889998887666899999****************************** PP
   S: 75   Grllgkalqdgrlldlplsksfyklllgkklsledleevdpelykslkeikenaes............dieelgldltfsvseei.....lgetkeeeL 156
           Gr+++kalqdgrlldlpls++fyklllg++l+l d+ ++d+el k l e++ ++e+            +   ++l +   + e++     l+ + +  L
   Q: 1490 GRIMAKALQDGRLLDLPLSTAFYKLLLGQELDLYDILSFDAELGKILRELQVLVERkrflescsnhsqQ--IEELGFHGAPIEDLcldftLPGYPDFVL 1586
           ***************************************************999444455555555442..333444444444445566688899999* PP
   S: 157  kpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevle 254
           k+g en+ V + N+eeY++lvv+++lk+gi +qveaf++Gfn+v+++++l++F+++el++licG+ e ++ e+l +++k+++gyt++spai +++e++ 
   Q: 1587 KEGEENTVVCIYNLEEYISLVVDATLKTGIMRQVEAFKAGFNQVFDISSLQIFSPQELDYLICGRrELWEPETLVEHIKFDHGYTSKSPAIVNLLEIMT 1685
           *****************************************************************999******************************* PP
   S: 255  efsseerkafLqFvTgssrlPlgGfaelkprlfvirk...............dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kgFel 335
           ef+ e++ af+qFvTg +rlP+gG+a+l+p+l+++rk               +++dd+lPs++TC+nyLkLP+Ys+ke++++kLlyAi+e+  +F+l
   Q: 1686 EFTPEQQHAFCQFVTGAPRLPPGGLASLNPKLTIVRKhsstaantsnaagaaESADDDLPSVMTCANYLKLPPYSTKEVMHKKLLYAINEGqGSFDL 1782
           **************************************************988899***********************************889987 PP

Organism

Aegilops tauschii

Protein Sequence
(Fasta)

MDDDEEGHGA FPHGLTSASS ALQGLLRKLG AGLDDMLPSS ALSAAAAAAS SSSMSGPNGA 60
RMKSMLAGLR ADGEEGRQVE ALTQLCEMLS IGTEDTLAGF SVDSFVPVLV GLLNHESNPD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACGACG ACGAGGAGGG CCACGGGGCC TTCCCCCACG GCCTCACCTC CGCCAGCAGC 60
GCCCTGCAGG GGCTGCTCAG GAAGCTCGGC GCCGGCCTGG ACGACATGCT GCCGTCGTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0436--Ligase
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR000225--Armadillo
IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00185--ARM
SM00119--HECTc

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

KEGG

ats:F775_26384

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001502	Ailuropoda melanoleuca	38.69	1.00e-128	454.00
IUUC-Atr-002821	Amborella trichopoda	63.88	0.00e+00	1969.00
IUUC-Apl-003531	Anas platyrhynchos	37.32	5.00e-117	416.00
IUUC-Aly-005962	Arabidopsis lyrata	64.14	0.00e+00	1929.00
IUUC-Ath-006636	Arabidopsis thaliana	63.63	0.00e+00	1924.00
IUUC-Ago-007875	Ashbya gossypii	35.95	2.00e-83	303.00
IUUC-Acl-008242	Aspergillus clavatus	39.97	8.00e-109	388.00
IUUC-Afu-008812	Aspergillus fumigatus	40.59	1.00e-111	398.00
IUUC-Ani-009407	Aspergillus nidulans	36.59	4.00e-107	383.00
IUUC-Ang-009763	Aspergillus niger	37.56	2.00e-104	374.00
IUUC-Ate-010459	Aspergillus terreus	36.23	8.00e-93	335.00
IUUC-Ame-011761	Astyanax mexicanus	38.52	4.00e-129	456.00
IUUC-Bta-013070	Bos taurus	38.69	2.00e-128	454.00
IUUC-Bdi-014046	Brachypodium distachyon	83.80	0.00e+00	2685.00
IUUC-Bol-015942	Brassica oleracea	62.78	0.00e+00	1931.00
IUUC-Bra-016849	Brassica rapa	62.84	0.00e+00	1940.00
IUUC-Cel-018153	Caenorhabditis elegans	36.78	4.00e-93	337.00
IUUC-Cja-019046	Callithrix jacchus	38.69	3.00e-128	453.00
IUUC-Cfa-020521	Canis familiaris	38.54	4.00e-128	452.00
IUUC-Cpo-021639	Cavia porcellus	38.83	6.00e-128	452.00
IUUC-Cre-022767	Chlamydomonas reinhardtii	51.56	1.00e-143	502.00
IUUC-Csa-023231	Chlorocebus sabaeus	38.69	3.00e-128	453.00
IUUC-Cho-024380	Choloepus hoffmanni	35.33	6.00e-109	389.00
IUUC-Cgl-026716	Colletotrichum gloeosporioides	35.81	3.00e-112	400.00
IUUC-Cne-026857	Cryptococcus neoformans	38.64	1.00e-93	338.00
IUUC-Cme-027226	Cyanidioschyzon merolae	37.71	2.00e-79	290.00
IUUC-Dre-028174	Danio rerio	38.08	8.00e-128	451.00
IUUC-Dor-030939	Dipodomys ordii	34.89	5.00e-105	376.00
IUUC-Dse-031444	Dothistroma septosporum	34.43	2.00e-105	377.00
IUUC-Dme-031739	Drosophila melanogaster	35.00	5.00e-86	313.00
IUUC-Ete-032345	Echinops telfairi	33.58	3.00e-96	346.00
IUUC-Eca-033229	Equus caballus	38.69	1.00e-126	448.00
IUUC-Eeu-035205	Erinaceus europaeus	38.39	5.00e-125	442.00
IUUC-Fca-036444	Felis catus	38.45	2.00e-126	447.00
IUUC-Fal-037131	Ficedula albicollis	38.98	2.00e-129	457.00
IUUC-Fox-038035	Fusarium oxysporum	39.34	3.00e-110	391.00
IUUC-Gmo-039497	Gadus morhua	38.81	8.00e-130	458.00
IUUC-Ggr-040057	Gaeumannomyces graminis	36.27	3.00e-108	387.00
IUUC-Gga-041021	Gallus gallus	38.83	1.00e-128	454.00
IUUC-Gac-042474	Gasterosteus aculeatus	38.52	5.00e-129	456.00
IUUC-Gma-043060	Glycine max	65.78	0.00e+00	2054.00
IUUC-Ggo-044855	Gorilla gorilla	38.69	4.00e-128	452.00
IUUC-Hsa-046147	Homo sapiens	38.69	3.00e-128	453.00
IUUC-Hvu-047775	Hordeum vulgare	95.07	0.00e+00	3120.00
IUUC-Itr-048131	Ictidomys tridecemlineatus	38.83	1.00e-128	454.00
IUUC-Lch-049818	Latimeria chalumnae	36.39	6.00e-118	419.00
IUUC-Loc-051777	Lepisosteus oculatus	38.81	1.00e-129	457.00
IUUC-Lma-052990	Leptosphaeria maculans	38.33	1.00e-105	377.00
IUUC-Laf-053727	Loxodonta africana	38.69	3.00e-128	453.00
IUUC-Mcc-055799	Macaca mulatta	38.69	3.00e-128	453.00
IUUC-Meu-056065	Macropus eugenii	36.07	1.00e-104	375.00
IUUC-Mor-057054	Magnaporthe oryzae	39.40	2.00e-107	384.00
IUUC-Mpo-057417	Magnaporthe poae	39.33	2.00e-106	381.00
IUUC-Mtr-057849	Medicago truncatula	64.18	0.00e+00	1994.00
IUUC-Mla-058870	Melampsora laricipopulina	37.21	6.00e-96	345.00
IUUC-Mga-059580	Meleagris gallopavo	33.18	2.00e-61	231.00
IUUC-Mvi-060507	Microbotryum violaceum	36.77	3.00e-115	410.00
IUUC-Mmr-060816	Microcebus murinus	38.69	6.00e-128	452.00
IUUC-Mdo-062866	Monodelphis domestica	36.33	6.00e-106	379.00
IUUC-Mmu-063906	Mus musculus	38.39	6.00e-126	445.00
IUUC-Mac-065153	Musa acuminata	64.28	0.00e+00	1024.00
IUUC-Mpu-066199	Mustela putorius furo	38.69	2.00e-128	454.00
IUUC-Mlu-067110	Myotis lucifugus	38.54	8.00e-127	448.00
IUUC-Nfi-068482	Neosartorya fischeri	40.59	2.00e-111	397.00
IUUC-Ncr-068906	Neurospora crassa	39.51	4.00e-108	386.00
IUUC-Nle-069410	Nomascus leucogenys	38.69	2.00e-128	453.00
IUUC-Opr-070401	Ochotona princeps	32.85	1.00e-91	331.00
IUUC-Ont-072100	Oreochromis niloticus	38.37	2.00e-129	457.00
IUUC-Oan-073121	Ornithorhynchus anatinus	38.39	5.00e-128	452.00
IUUC-Ocu-074623	Oryctolagus cuniculus	38.69	5.00e-128	452.00
IUUC-Oba-074990	Oryza barthii	68.91	0.00e+00	1987.00
IUUC-Oni-082469	Oryza nivara	69.36	0.00e+00	2056.00
IUUC-Oru-084607	Oryza rufipogon	68.87	0.00e+00	1993.00
IUUC-Ola-087173	Oryzias latipes	38.23	7.00e-129	455.00
IUUC-Olu-087871	Ostreococcus lucimarinus	45.94	6.00e-131	460.00
IUUC-Oga-087908	Otolemur garnettii	38.69	1.00e-127	451.00
IUUC-Oar-090277	Ovis aries	38.69	2.00e-128	453.00
IUUC-Ptr-091543	Pan troglodytes	38.69	3.00e-128	453.00
IUUC-Pan-092243	Papio anubis	38.69	2.00e-128	453.00
IUUC-Psi-093150	Pelodiscus sinensis	38.54	9.00e-128	451.00
IUUC-Pno-094891	Phaeosphaeria nodorum	39.50	6.00e-107	382.00
IUUC-Ppa-095181	Physcomitrella patens	54.50	0.00e+00	721.00
IUUC-Pfo-096267	Poecilia formosa	38.08	2.00e-127	450.00
IUUC-Pab-098072	Pongo abelii	38.69	4.00e-128	452.00
IUUC-Pop-099190	Populus trichocarpa	66.41	0.00e+00	2025.00
IUUC-Pca-100311	Procavia capensis	39.00	4.00e-128	452.00
IUUC-Ppe-101284	Prunus persica	67.00	0.00e+00	2130.00
IUUC-Pva-102215	Pteropus vampyrus	38.91	1.00e-105	378.00
IUUC-Pgr-103694	Puccinia graminis	36.66	1.00e-97	351.00
IUUC-Ptt-103916	Puccinia triticina	36.07	9.00e-91	328.00
IUUC-Pyt-104508	Pyrenophora triticirepentis	38.46	2.00e-106	380.00
IUUC-Rno-105315	Rattus norvegicus	38.83	6.00e-128	452.00
IUUC-Sce-106273	Saccharomyces cerevisiae	36.70	7.00e-75	275.00
IUUC-Sha-106835	Sarcophilus harrisii	38.39	7.00e-127	448.00
IUUC-Sja-107943	Schizosaccharomyces japonicus	38.58	2.00e-96	347.00
IUUC-Spo-108081	Schizosaccharomyces pombe	38.00	1.00e-88	321.00
IUUC-Ssl-108560	Sclerotinia sclerotiorum	40.12	3.00e-103	370.00
IUUC-Smo-109590	Selaginella moellendorffii	60.45	0.00e+00	784.00
IUUC-Sit-109757	Setaria italica	76.31	0.00e+00	2509.00
IUUC-Sly-111469	Solanum lycopersicum	64.37	0.00e+00	2107.00
IUUC-Stu-112896	Solanum tuberosum	65.81	0.00e+00	954.00
IUUC-Sar-113224	Sorex araneus	46.11	4.00e-90	326.00
IUUC-Sbi-114313	Sorghum bicolor	78.83	0.00e+00	2605.00
IUUC-Sre-114993	Sporisorium reilianum	34.39	6.00e-95	342.00
IUUC-Ssc-115535	Sus scrofa	36.46	6.00e-109	389.00
IUUC-Tru-118669	Takifugu rubripes	38.23	8.00e-129	455.00
IUUC-Tsy-119373	Tarsius syrichta	33.83	1.00e-89	325.00
IUUC-Tni-120049	Tetraodon nigroviridis	37.52	1.00e-92	333.00
IUUC-Tca-121779	Theobroma cacao	65.82	0.00e+00	2080.00
IUUC-Tre-122195	Trichoderma reesei	38.46	2.00e-106	380.00
IUUC-Tvi-122650	Trichoderma virens	35.23	4.00e-107	383.00
IUUC-Tur-126295	Triticum urartu	99.25	0.00e+00	3198.00
IUUC-Tme-126964	Tuber melanosporum	36.25	3.00e-108	386.00
IUUC-Tbe-128149	Tupaia belangeri	32.79	3.00e-88	320.00
IUUC-Ttr-128165	Tursiops truncatus	38.69	4.00e-128	452.00
IUUC-Uma-129365	Ustilago maydis	36.58	3.00e-84	307.00
IUUC-Vpa-130678	Vicugna pacos	38.54	5.00e-128	452.00
IUUC-Vvi-131147	Vitis vinifera	67.02	0.00e+00	2097.00
IUUC-Xtr-132636	Xenopus tropicalis	37.99	1.00e-121	431.00
IUUC-Xma-133458	Xiphophorus maculatus	38.66	4.00e-130	459.00
IUUC-Yli-134481	Yarrowia lipolytica	40.08	3.00e-97	350.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence