iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Afu-008871

Ensembl Protein ID

CADAFUAP00002300

UniProt Accession

Q4WLU7; Q4WLU7_ASPFU

Genbank Protein ID

EAL89067.1

Protein Name

Ubiquitin C-terminal hydrolase, putative

Genbank Nucleotide ID

AAHF01000006

Gene Name

AFUA_6G12270

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADAFUAG00002300	CADAFUAT00002300	CADAFUAP00002300

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	7.60e-39	132.8	834	1129

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 135  kkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkk 225
           + ++ + ++dlF g++ks i  ++ +   s+ee  +d++++v         ++ ++++  + +++++ +          ++ +e+   ++k
   Q: 834  DGEQLDQVKDLFYGRTKSYILAEAGA--RSKEEWWCDIKVDVATGPR----DIYSAIDGAFDAQKVNVD----------DTVVEQFGAISK 908
           44555667777777777776654433..3456777777777776663....677777777777777742..........344667778*** PP
   S: 226  lPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts..........................peekqke................ 274
           lP+vL ++ +R++f+  +ks+ k + ++e+++++ l++++ +                                e                
   Q: 909  LPPVLQIQVQRVQFDPVKKSSFKSTHHLELKETIYLDRYMDTqhpeimnrrrqcwewkntlktledrrA-----Ellrqtendgldmatlf 994
           ****************************************99566666666666665555555555550.....05555555555566666 PP
   S: 275  ...................................................................kkkYeLiavvvHsGslssGHYvay 298
                                                                              +  Y+L+av vH+Gs++ GHY+ y
   Q: 995  dsaraviedldqlkadpetaddgldfnpqlpselaqlsqiakaelnyveqeikdtqtmissqfvdfkHLAYRLYAVFVHHGSVEFGHYYIY 1085
           66666666666666666666667777777777777777777788888888888888999999999999*********************** PP
   S: 299  vknekgk.WllfdDskVtevke.eevleetg....staYvlfYk 336
           + + +++ W +++D++Vtev+  +e+ ++++     t+Y l+Y 
   Q: 1086 IFDFRKNvWRKYNDTEVTEVTNtDEIFKNQErqnpPTPYFLVYV 1129
           ***88888************753788887768999********6 PP

Organism

Aspergillus fumigatus

Protein Sequence
(Fasta)

MTKSNQSFLP QAEQKRSTGN PSKVSAVCWK CRYHLQLVVS STPGIGQSSQ GFADHLHHLV 60
YKSGRQKGGA SPAEITPKGQ TVETFQYECS YLTCPVTVAV RIASPILADE WVRQLVDPDL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACCAAAT CGAATCAGAG CTTCCTACCC CAAGCGGAGC AGAAAAGGAG CACCGGAAAT 60
CCCTCCAAAG TGTCAGCGGT ATGCTGGAAG TGTCGATATC ATCTTCAACT TGTTGTTAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR025305--UCH_repeat_domain
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF13446--RPT
PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

afm:AFUA_6G12270

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001836	Ailuropoda melanoleuca	22.84	1.00e-15	77.40
IUUC-Ago-007865	Ashbya gossypii	36.95	1.00e-44	173.00
IUUC-Acl-008164	Aspergillus clavatus	82.30	0.00e+00	1987.00
IUUC-Afl-008717	Aspergillus flavus	68.49	0.00e+00	1645.00
IUUC-Ani-009503	Aspergillus nidulans	65.54	0.00e+00	1369.00
IUUC-Ang-009577	Aspergillus niger	66.97	0.00e+00	1601.00
IUUC-Aor-009928	Aspergillus oryzae	70.02	0.00e+00	1393.00
IUUC-Ate-010275	Aspergillus terreus	65.23	0.00e+00	1389.00
IUUC-Ame-010624	Astyanax mexicanus	25.42	6.00e-14	71.20
IUUC-Bgr-011993	Blumeria graminis	32.78	6.00e-144	503.00
IUUC-Bta-013166	Bos taurus	22.81	4.00e-14	72.40
IUUC-Bci-013999	Botrytis cinerea	32.76	1.00e-147	515.00
IUUC-Cpo-021817	Cavia porcellus	31.36	1.00e-11	63.90
IUUC-Csa-023446	Chlorocebus sabaeus	33.66	4.00e-11	62.40
IUUC-Cho-024343	Choloepus hoffmanni	43.28	8.00e-12	64.30
IUUC-Cin-025302	Ciona intestinalis	36.36	2.00e-10	58.90
IUUC-Cgl-026575	Colletotrichum gloeosporioides	22.78	2.00e-25	109.00
IUUC-Cne-026803	Cryptococcus neoformans	22.51	8.00e-13	68.20
IUUC-Cme-027167	Cyanidioschyzon merolae	29.44	7.00e-11	61.60
IUUC-Dor-030955	Dipodomys ordii	31.40	2.00e-10	60.10
IUUC-Dse-031290	Dothistroma septosporum	26.92	5.00e-52	198.00
IUUC-Ete-032323	Echinops telfairi	34.34	4.00e-11	62.40
IUUC-Eca-034300	Equus caballus	34.65	1.00e-11	64.30
IUUC-Fca-035876	Felis catus	23.78	7.00e-18	84.70
IUUC-Fox-037752	Fusarium oxysporum	24.75	2.00e-33	136.00
IUUC-Fso-038114	Fusarium solani	24.93	3.00e-33	136.00
IUUC-Ggr-039843	Gaeumannomyces graminis	25.22	6.00e-20	92.00
IUUC-Itr-048276	Ictidomys tridecemlineatus	34.26	3.00e-12	65.50
IUUC-Kpa-049349	Komagataella pastoris	30.06	2.00e-94	338.00
IUUC-Lch-049692	Latimeria chalumnae	35.78	6.00e-12	65.10
IUUC-Loc-052070	Lepisosteus oculatus	23.86	1.00e-14	73.90
IUUC-Lma-053078	Leptosphaeria maculans	32.78	2.00e-92	332.00
IUUC-Meu-056416	Macropus eugenii	33.96	2.00e-11	63.50
IUUC-Mor-057281	Magnaporthe oryzae	24.63	2.00e-17	83.60
IUUC-Mpo-057451	Magnaporthe poae	24.60	2.00e-32	133.00
IUUC-Mla-058944	Melampsora laricipopulina	28.99	5.00e-34	138.00
IUUC-Mdo-061955	Monodelphis domestica	33.96	2.00e-11	64.30
IUUC-Mmu-063870	Mus musculus	34.65	1.00e-11	64.30
IUUC-Nfi-068458	Neosartorya fischeri	96.26	0.00e+00	2347.00
IUUC-Ncr-068739	Neurospora crassa	23.45	5.00e-46	178.00
IUUC-Opr-070214	Ochotona princeps	43.28	2.00e-11	63.50
IUUC-Oan-073054	Ornithorhynchus anatinus	35.05	2.00e-10	60.10
IUUC-Ocu-074102	Oryctolagus cuniculus	23.69	1.00e-16	80.90
IUUC-Ola-086393	Oryzias latipes	23.67	9.00e-14	71.20
IUUC-Oar-090266	Ovis aries	23.72	4.00e-17	82.00
IUUC-Psi-093459	Pelodiscus sinensis	24.32	2.00e-14	72.80
IUUC-Pno-095093	Phaeosphaeria nodorum	32.02	3.00e-73	268.00
IUUC-Pca-100718	Procavia capensis	34.34	2.00e-11	62.80
IUUC-Pva-102226	Pteropus vampyrus	34.00	1.00e-10	60.80
IUUC-Pgr-103515	Puccinia graminis	37.11	1.00e-34	140.00
IUUC-Ptt-103803	Puccinia triticina	33.33	1.00e-19	89.70
IUUC-Pte-104300	Pyrenophora teres	29.28	3.00e-129	455.00
IUUC-Pyt-104434	Pyrenophora triticirepentis	30.90	5.00e-76	278.00
IUUC-Sce-106441	Saccharomyces cerevisiae	29.28	3.00e-84	305.00
IUUC-Sha-107051	Sarcophilus harrisii	24.41	2.00e-15	76.60
IUUC-Sja-107936	Schizosaccharomyces japonicus	32.76	1.00e-43	170.00
IUUC-Spo-108381	Schizosaccharomyces pombe	30.70	6.00e-40	158.00
IUUC-Ssl-108532	Sclerotinia sclerotiorum	34.63	5.00e-154	536.00
IUUC-Sar-112977	Sorex araneus	30.93	1.00e-09	57.00
IUUC-Sre-115145	Sporisorium reilianum	26.17	5.00e-28	119.00
IUUC-Tsy-118971	Tarsius syrichta	26.83	3.00e-10	59.30
IUUC-Tre-122145	Trichoderma reesei	25.18	3.00e-35	142.00
IUUC-Tvi-122548	Trichoderma virens	24.97	7.00e-34	138.00
IUUC-Tme-126928	Tuber melanosporum	43.31	3.00e-77	281.00
IUUC-Tbe-127549	Tupaia belangeri	41.79	5.00e-11	62.00
IUUC-Ttr-128896	Tursiops truncatus	43.28	9.00e-12	64.30
IUUC-Uma-129338	Ustilago maydis	26.26	8.00e-28	118.00
IUUC-Vda-129742	Verticillium dahliae	24.81	5.00e-41	162.00
IUUC-Vpa-130500	Vicugna pacos	24.41	3.00e-12	66.20
IUUC-Xtr-132436	Xenopus tropicalis	24.58	5.00e-14	72.00
IUUC-Yli-134560	Yarrowia lipolytica	37.96	2.00e-55	209.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence