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Tag Content
UUCD2 ID IUUC-Mcc-055660
UUCD1 version UUC-MaM-00091
Ensembl Protein ID ENSMMUP00000001013.3
UniProt Accession F6RS36; F6RS36_MACMU
Genbank Protein ID ENSMMUP00000001013
Protein Name Uncharacterized protein
Genbank Nucleotide ID JSUE03016471
Gene Name NLE1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMMUG00000000751.3 ENSMMUT00000001081.3 ENSMMUP00000001013.3
ENSMMUG00000000751.3 ENSMMUT00000073987.1 ENSMMUP00000053946.1
ENSMMUG00000000751.3 ENSMMUT00000061242.1 ENSMMUP00000059044.1
ENSMMUG00000000751.3 ENSMMUT00000067752.1 ENSMMUP00000059060.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.20e-66 218.6 199 242
UBD/Beta-Prp 7.10e-79 266.2 108 303
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf......sd.tllvsGsdDgtikvWDlrtgvllk 37
           gH+ ++t+l++      ++ ++++s+s Dg++++WD++ g++++
   Q: 199  GHSKWITGLSWeplhanPEcRYVASSSKDGSVRIWDTTAGRCER 242
           8***************9889**********************86 PP
   

   UBD/Beta-Prp
   S: 44   llrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleet 132
           + +sl gh+++v +v fsp+gk+l++gs D t++ wdlst ++  t kgh + vls+s+sp+g+kl+sG +   i +wd +tg+ +  t
   Q: 108  CTSSLDGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGKKLASGCKNGQILLWDPSTGKQVGRT 196
           5789************************************************************************************* PP
   S: 133  lsghdgvvncvvv.....hpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvr 216
           l+gh+++++++++     +p++++++s+s+D+ vr+Wd   g++ r ltg ht+sv++l +  +g  l s+s+d+t+k+w  + g   r
   Q: 197  LAGHSKWITGLSWeplhaNPECRYVASSSKDGSVRIWDTTAGRCERILTG-HTQSVTCLRWGGDG-LLYSASQDRTIKVWRAHDGVLCR 283
           **********9873332257889**************************9.************98.*********************** PP
   S: 217  tlnghtdnvksvrfspnderl 237
           tl+gh  +v+ +++s  d  l
   Q: 284  TLQGHGHWVNTMALS-TDYAL 303
           **************9.44444 PP
   
Organism Macaca mulatta
Protein Sequence
(Fasta)
LPPRFLAQDE SVARDVQRLL VQFQDEGGQL LGSPFDVPVD ITPDRLQLVC NALLAQEDPL 60
PLAFFVHDAE IVSSLGKTLE SQAVETEKVL DIIYQPQAVF RVRAVTRCTS SLDGHSEAVI 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mcc-055660|E3,WD_repeat;UBD,Beta-Prp|Macaca mulatta
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGTACGCAGG ATGGCGGCGG CAGTGGCGGT GGGTGTGCGT GGATGGGGGC GGGGGGCGTC 60
GCGGCGCTAG GGCCCGGGTC CCTGAGGCCG GAGGGAAACG AAGTGGGGCT CTTCCGGGCG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mcc-055660|E3,WD_repeat;UBD,Beta-Prp|Macaca mulatta
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR012972--NLE
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF08154--NLE
PF00400--WD40
PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0005730--C:nucleolus
GO:0005840--C:ribosome
GO:0061484--P:hematopoietic stem cell homeostasis
GO:0001826--P:inner cell mass cell differentiation
GO:0001822--P:kidney development
GO:2001268--P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
GO:0045930--P:negative regulation of mitotic cell cycle
GO:0007219--P:Notch signaling pathway
GO:0090263--P:positive regulation of canonical Wnt signaling pathway
GO:0000027--P:ribosomal large subunit assembly
GO:0048705--P:skeletal system morphogenesis
GO:0001756--P:somitogenesis
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000437 Aegilops tauschii 58.37 1.00e-168 586.00
IUUC-Aml-001793 Ailuropoda melanoleuca 96.41 0.00e+00 942.00
IUUC-Atr-002507 Amborella trichopoda 57.71 5.00e-167 580.00
IUUC-Apl-003964 Anas platyrhynchos 85.02 0.00e+00 812.00
IUUC-Aly-006396 Arabidopsis lyrata 54.68 4.00e-161 560.00
IUUC-Ath-007278 Arabidopsis thaliana 55.32 9.00e-161 560.00
IUUC-Ago-007951 Ashbya gossypii 47.21 2.00e-128 452.00
IUUC-Acl-008298 Aspergillus clavatus 46.49 4.00e-121 428.00
IUUC-Afl-008581 Aspergillus flavus 51.94 3.00e-109 388.00
IUUC-Afu-008906 Aspergillus fumigatus 45.78 8.00e-121 427.00
IUUC-Ani-009189 Aspergillus nidulans 43.65 2.00e-115 409.00
IUUC-Ang-009630 Aspergillus niger 45.73 2.00e-122 432.00
IUUC-Aor-010038 Aspergillus oryzae 46.40 3.00e-128 452.00
IUUC-Ate-010278 Aspergillus terreus 46.18 3.00e-122 431.00
IUUC-Ame-011890 Astyanax mexicanus 81.18 0.00e+00 822.00
IUUC-Bgr-012011 Blumeria graminis 48.03 1.00e-129 456.00
IUUC-Bta-012964 Bos taurus 95.57 0.00e+00 939.00
IUUC-Bci-013592 Botrytis cinerea 44.09 1.00e-119 423.00
IUUC-Bdi-015035 Brachypodium distachyon 58.46 7.00e-170 590.00
IUUC-Bol-015501 Brassica oleracea 55.98 9.00e-161 559.00
IUUC-Bra-017642 Brassica rapa 55.77 3.00e-160 558.00
IUUC-Cel-018430 Caenorhabditis elegans 58.58 6.00e-168 583.00
IUUC-Cja-019125 Callithrix jacchus 97.89 0.00e+00 951.00
IUUC-Cfa-021013 Canis familiaris 95.15 0.00e+00 855.00
IUUC-Cpo-021743 Cavia porcellus 95.14 0.00e+00 935.00
IUUC-Cre-022973 Chlamydomonas reinhardtii 45.05 2.00e-117 416.00
IUUC-Csa-024270 Chlorocebus sabaeus 99.38 0.00e+00 988.00
IUUC-Cin-025795 Ciona intestinalis 65.69 0.00e+00 684.00
IUUC-Csv-025953 Ciona savignyi 67.16 0.00e+00 682.00
IUUC-Cgl-026517 Colletotrichum gloeosporioides 50.93 4.00e-107 381.00
IUUC-Cne-026901 Cryptococcus neoformans 48.34 1.00e-138 486.00
IUUC-Cme-027281 Cyanidioschyzon merolae 47.23 1.00e-113 403.00
IUUC-Dre-028515 Danio rerio 77.52 0.00e+00 800.00
IUUC-Dno-029596 Dasypus novemcinctus 96.45 0.00e+00 952.00
IUUC-Dor-030494 Dipodomys ordii 94.65 0.00e+00 942.00
IUUC-Dse-031538 Dothistroma septosporum 48.03 4.00e-129 454.00
IUUC-Dme-031974 Drosophila melanogaster 58.16 9.00e-169 586.00
IUUC-Ete-032948 Echinops telfairi 96.17 1.00e-116 413.00
IUUC-Eca-033399 Equus caballus 97.45 0.00e+00 946.00
IUUC-Eeu-035013 Erinaceus europaeus 93.40 7.00e-116 410.00
IUUC-Fca-035860 Felis catus 96.20 0.00e+00 940.00
IUUC-Fal-037069 Ficedula albicollis 87.20 3.00e-131 460.00
IUUC-Fox-038059 Fusarium oxysporum 46.35 2.00e-124 439.00
IUUC-Fso-038445 Fusarium solani 46.56 7.00e-125 440.00
IUUC-Gmo-039319 Gadus morhua 75.96 0.00e+00 734.00
IUUC-Ggr-040095 Gaeumannomyces graminis 47.00 1.00e-121 429.00
IUUC-Gga-040303 Gallus gallus 85.20 2.00e-129 454.00
IUUC-Gac-042267 Gasterosteus aculeatus 78.57 0.00e+00 766.00
IUUC-Gma-043974 Glycine max 57.45 4.00e-170 590.00
IUUC-Ggo-044637 Gorilla gorilla 98.30 0.00e+00 947.00
IUUC-Hsa-046128 Homo sapiens 98.54 0.00e+00 968.00
IUUC-Hvu-047373 Hordeum vulgare 58.03 2.00e-168 585.00
IUUC-Itr-048070 Ictidomys tridecemlineatus 95.66 0.00e+00 949.00
IUUC-Kpa-049274 Komagataella pastoris 43.90 4.00e-126 444.00
IUUC-Lch-049907 Latimeria chalumnae 81.16 0.00e+00 817.00
IUUC-Lpe-050778 Leersia perrieri 53.25 1.00e-151 529.00
IUUC-Loc-051889 Lepisosteus oculatus 79.87 0.00e+00 822.00
IUUC-Lma-053041 Leptosphaeria maculans 49.77 4.00e-117 415.00
IUUC-Laf-053598 Loxodonta africana 95.88 0.00e+00 958.00
IUUC-Meu-056197 Macropus eugenii 79.09 0.00e+00 785.00
IUUC-Mor-056949 Magnaporthe oryzae 46.38 5.00e-119 421.00
IUUC-Mpo-057571 Magnaporthe poae 44.75 2.00e-63 236.00
IUUC-Mtr-058530 Medicago truncatula 58.51 1.00e-166 579.00
IUUC-Mla-059133 Melampsora laricipopulina 46.08 1.00e-123 436.00
IUUC-Mga-059252 Meleagris gallopavo 84.38 0.00e+00 658.00
IUUC-Mvi-060522 Microbotryum violaceum 49.80 1.00e-135 476.00
IUUC-Mmr-061117 Microcebus murinus 95.07 0.00e+00 950.00
IUUC-Mdo-062892 Monodelphis domestica 88.77 0.00e+00 892.00
IUUC-Mmu-064108 Mus musculus 95.98 0.00e+00 911.00
IUUC-Mac-064430 Musa acuminata 59.10 5.00e-172 597.00
IUUC-Mpu-065882 Mustela putorius furo 95.77 0.00e+00 933.00
IUUC-Mlu-068123 Myotis lucifugus 95.78 0.00e+00 943.00
IUUC-Nfi-068484 Neosartorya fischeri 46.18 6.00e-121 427.00
IUUC-Ncr-068649 Neurospora crassa 43.58 8.00e-116 410.00
IUUC-Nle-069140 Nomascus leucogenys 98.30 0.00e+00 947.00
IUUC-Opr-070220 Ochotona princeps 88.61 0.00e+00 834.00
IUUC-Ont-072643 Oreochromis niloticus 80.46 0.00e+00 818.00
IUUC-Ocu-074007 Oryctolagus cuniculus 95.98 0.00e+00 910.00
IUUC-Oba-075904 Oryza barthii 58.89 3.00e-171 595.00
IUUC-Obr-076280 Oryza brachyantha 58.46 3.00e-170 591.00
IUUC-Ogl-077425 Oryza glaberrima 58.89 3.00e-171 594.00
IUUC-Ogu-078586 Oryza glumaepatula 58.89 3.00e-171 594.00
IUUC-Oin-079489 Oryza indica 56.75 3.00e-162 564.00
IUUC-Olo-080766 Oryza longistaminata 58.76 4.00e-171 594.00
IUUC-Ome-081905 Oryza meridionalis 58.89 2.00e-171 595.00
IUUC-Oni-083022 Oryza nivara 58.89 1.00e-171 595.00
IUUC-Opu-083615 Oryza punctata 58.89 2.00e-171 595.00
IUUC-Oru-085076 Oryza rufipogon 58.89 1.00e-171 595.00
IUUC-Osa-085516 Oryza sativa 58.89 1.00e-171 595.00
IUUC-Ola-087290 Oryzias latipes 78.36 0.00e+00 802.00
IUUC-Olu-087898 Ostreococcus lucimarinus 53.35 2.00e-143 501.00
IUUC-Oga-088980 Otolemur garnettii 95.54 0.00e+00 931.00
IUUC-Oar-089580 Ovis aries 95.85 0.00e+00 818.00
IUUC-Ptr-090845 Pan troglodytes 97.88 0.00e+00 943.00
IUUC-Pan-092836 Papio anubis 99.79 0.00e+00 977.00
IUUC-Psi-093965 Pelodiscus sinensis 82.46 9.00e-56 208.00
IUUC-Pno-095052 Phaeosphaeria nodorum 47.43 1.00e-122 433.00
IUUC-Ppa-095432 Physcomitrella patens 57.32 3.00e-169 588.00
IUUC-Pfo-096963 Poecilia formosa 72.27 0.00e+00 704.00
IUUC-Pab-097716 Pongo abelii 94.48 0.00e+00 902.00
IUUC-Pop-099224 Populus trichocarpa 58.72 2.00e-171 595.00
IUUC-Pca-100682 Procavia capensis 92.68 0.00e+00 677.00
IUUC-Ppe-101819 Prunus persica 58.02 4.00e-169 587.00
IUUC-Pva-102338 Pteropus vampyrus 94.86 0.00e+00 731.00
IUUC-Pgr-103583 Puccinia graminis 54.01 1.00e-130 459.00
IUUC-Ptt-103737 Puccinia triticina 44.11 9.00e-99 353.00
IUUC-Pte-104150 Pyrenophora teres 50.23 6.00e-122 431.00
IUUC-Pyt-104606 Pyrenophora triticirepentis 50.00 1.00e-121 430.00
IUUC-Rno-105987 Rattus norvegicus 95.76 0.00e+00 934.00
IUUC-Sce-106315 Saccharomyces cerevisiae 47.07 1.00e-129 456.00
IUUC-Sha-107273 Sarcophilus harrisii 89.81 0.00e+00 903.00
IUUC-Sja-107677 Schizosaccharomyces japonicus 44.36 1.00e-117 416.00
IUUC-Spo-108092 Schizosaccharomyces pombe 48.74 6.00e-123 434.00
IUUC-Ssl-108442 Sclerotinia sclerotiorum 43.74 1.00e-114 406.00
IUUC-Smo-108855 Selaginella moellendorffii 56.06 2.00e-163 568.00
IUUC-Sit-110329 Setaria italica 59.10 2.00e-171 595.00
IUUC-Sly-111830 Solanum lycopersicum 59.96 4.00e-174 604.00
IUUC-Stu-112603 Solanum tuberosum 59.96 4.00e-174 604.00
IUUC-Sar-113504 Sorex araneus 86.27 6.00e-75 275.00
IUUC-Sbi-114560 Sorghum bicolor 58.24 1.00e-168 585.00
IUUC-Sre-115133 Sporisorium reilianum 41.46 8.00e-123 434.00
IUUC-Ssc-115903 Sus scrofa 96.84 0.00e+00 944.00
IUUC-Tgu-116798 Taeniopygia guttata 85.20 0.00e+00 853.00
IUUC-Tru-118361 Takifugu rubripes 78.20 0.00e+00 803.00
IUUC-Tsy-118849 Tarsius syrichta 96.05 0.00e+00 952.00
IUUC-Tni-120094 Tetraodon nigroviridis 77.53 0.00e+00 803.00
IUUC-Tca-121634 Theobroma cacao 58.30 9.00e-168 583.00
IUUC-Tre-122051 Trichoderma reesei 45.62 2.00e-118 419.00
IUUC-Tvi-122322 Trichoderma virens 47.08 3.00e-122 432.00
IUUC-Tae-125822 Triticum aestivum 58.24 9.00e-169 586.00
IUUC-Tur-126766 Triticum urartu 52.00 2.00e-160 559.00
IUUC-Tme-127175 Tuber melanosporum 50.61 7.00e-132 464.00
IUUC-Tbe-127779 Tupaia belangeri 95.32 0.00e+00 832.00
IUUC-Ttr-128224 Tursiops truncatus 91.36 0.00e+00 808.00
IUUC-Uma-129537 Ustilago maydis 41.82 4.00e-124 438.00
IUUC-Vda-129927 Verticillium dahliae 45.40 2.00e-109 389.00
IUUC-Vpa-130658 Vicugna pacos 83.23 0.00e+00 806.00
IUUC-Vvi-131659 Vitis vinifera 58.85 4.00e-171 594.00
IUUC-Xtr-132918 Xenopus tropicalis 77.05 0.00e+00 785.00
IUUC-Xma-133700 Xiphophorus maculatus 80.46 0.00e+00 815.00
IUUC-Yli-134478 Yarrowia lipolytica 49.51 5.00e-139 487.00
IUUC-Zma-135835 Zea mays 55.78 2.00e-165 575.00
Created Date 25-Jun-2017

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