iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-053920

Ensembl Protein ID

ENSLAFP00000024477.1

UniProt Accession

G3U9G9; G3U9G9_LOXAF

Protein Name

Uncharacterized protein

Gene Name

UBQLN2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000030258.1	ENSLAFT00000033947.1	ENSLAFP00000024477.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	1.70e-10	41.0	478	515
ULD/UDP/UBQ/UBQ_PIM	1.90e-23	82.6	33	106

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGF.dreealqaLraannnleaAveyLl 39
           ++++leql +MGF +re++lqaL a++++++aA+e+Ll
   Q: 478  FQQQLEQLNAMGFlNREANLQALIATGGDINAAIERLL 515
           799**********************************9 PP

ULD/UDP/UBQ/UBQ_PIM

   S: 1    mkltvktlkgkefelevseddtveelKekiakesgvppeqqkLIyaGkiLkDdttLselgikdgsvvhlvvkksk 75
           +k+tvkt+k+ke e+ v e+++v+++Ke+i+k+++ + +q+ LI+aGkiLkD++tL ++gi+dg +vhlv+k ++
   Q: 33   IKVTVKTPKEKE-EFAVPENSSVQQFKEAISKRFKSQTDQLVLIFAGKILKDQDTLIQHGIHDGLTVHLVIKSQN 106
           69**********.***********************************************************986 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MAENGESNGL PHPSRGPAAA QGSATAAAEP KIIKVTVKTP KEKEEFAVPE NSSVQQFKEA 60
ISKRFKSQTD QLVLIFAGKI LKDQDTLIQH GIHDGLTVHL VIKSQNRPQG QSTQPSNAAG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTGAGA ACGGCGAGAG CAACGGCCTC CCGCACCCCT CCCGCGGCCC TGCTGCGGCC 60
CAAGGCTCGG CCACTGCCGC CGCGGAACCC AAAATCATCA AAGTCACTGT GAAGACCCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016024--ARM-type_fold
IPR006636--STI1_HS-bd
IPR015940--UBA
IPR009060--UBA-like
IPR015496--Ubiquilin
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50030--UBA
PS50053--UBIQUITIN_2

Pfam

PF00627--UBA
PF00240--ubiquitin

SMART

SM00727--STI1
SM00165--UBA
SM00213--UBQ

Gene Ontology

GO:0005829--C:cytosol
GO:0005886--C:plasma membrane
GO:1900186--P:negative regulation of clathrin-dependent endocytosis
GO:1904021--P:negative regulation of G-protein coupled receptor internalization
GO:1903071--P:positive regulation of ER-associated ubiquitin-dependent protein catabolic process
GO:2000785--P:regulation of autophagosome assembly
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cre-022634	Chlamydomonas reinhardtii	48.15	2.00e-11	63.20
IUUC-Csv-026009	Ciona savignyi	48.95	5.00e-79	288.00
IUUC-Cne-026833	Cryptococcus neoformans	28.26	4.00e-14	72.40
IUUC-Fso-038204	Fusarium solani	40.85	1.00e-07	51.20
IUUC-Hvu-047094	Hordeum vulgare	50.98	3.00e-09	53.90
IUUC-Mvi-060466	Microbotryum violaceum	54.76	2.00e-08	53.10
IUUC-Pop-099077	Populus trichocarpa	32.33	2.00e-42	166.00
IUUC-Pgr-103261	Puccinia graminis	54.76	2.00e-07	50.10
IUUC-Sce-106332	Saccharomyces cerevisiae	33.64	2.00e-16	80.10
IUUC-Spo-108223	Schizosaccharomyces pombe	28.38	3.00e-10	59.30
IUUC-Sre-115081	Sporisorium reilianum	26.09	6.00e-12	65.10

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence