iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ptr-090781

Ensembl Protein ID

ENSPTRP00000037734.5

UniProt Accession

H2QYP6; H2QYP6_PANTR

Genbank Protein ID

JAA00973.1; JAA15189.1; JAA32005.1; JAA39422.1

Protein Name

Ubiquilin 2

Genbank Nucleotide ID

AACZ03138893; GABF01006956; GABD01001095; GABE01005317

Gene Name

UBQLN2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000021958.5	ENSPTRT00000040840.5	ENSPTRP00000037734.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	1.70e-10	40.7	582	619
ULD/UDP/UBQ/UBQ_PIM	1.90e-23	82.2	33	106

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGF.dreealqaLraannnleaAveyLl 39
           ++++leql +MGF +re++lqaL a++++++aA+e+Ll
   Q: 582  FQQQLEQLNAMGFlNREANLQALIATGGDINAAIERLL 619
           799**********************************9 PP

ULD/UDP/UBQ/UBQ_PIM

   S: 1    mkltvktlkgkefelevseddtveelKekiakesgvppeqqkLIyaGkiLkDdttLselgikdgsvvhlvvkksk 75
           +k+tvkt+k+ke e+ v e+++v+++Ke+i+k+++ + +q+ LI+aGkiLkD++tL ++gi+dg +vhlv+k ++
   Q: 33   IKVTVKTPKEKE-EFAVPENSSVQQFKEAISKRFKSQTDQLVLIFAGKILKDQDTLIQHGIHDGLTVHLVIKSQN 106
           69**********.***********************************************************986 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MAENGESSGP PRPSRGPAAA QGSAAAPAEP KIIKVTVKTP KEKEEFAVPE NSSVQQFKEA 60
ISKRFKSQTD QLVLIFAGKI LKDQDTLIQH GIHDGLTVHL VIKSQNRPQG QSTQPSNAAG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCCTGACCC GGCCCAGCCC GCTGCGGCGG CGCCTCCTTC CTTCCTCCTT CCCTCGCGCT 60
CTCTCTTTCG CCCGCCCGCG CCTTCCCTGC CCGCNTGCGT CACCGCGGCC GCCATGGCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016024--ARM-type_fold
IPR006636--STI1_HS-bd
IPR015940--UBA
IPR009060--UBA-like
IPR015496--Ubiquilin
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50030--UBA
PS50053--UBIQUITIN_2

Pfam

PF00627--UBA
PF00240--ubiquitin

SMART

SM00727--STI1
SM00165--UBA
SM00213--UBQ

Gene Ontology

GO:0005829--C:cytosol
GO:0005886--C:plasma membrane
GO:1900186--P:negative regulation of clathrin-dependent endocytosis
GO:1904021--P:negative regulation of G-protein coupled receptor internalization
GO:1903071--P:positive regulation of ER-associated ubiquitin-dependent protein catabolic process
GO:2000785--P:regulation of autophagosome assembly
GO:0030433--P:ubiquitin-dependent ERAD pathway

KEGG

ptr:743819

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Acl-008361	Aspergillus clavatus	53.19	4.00e-07	49.70
IUUC-Bta-013571	Bos taurus	97.24	0.00e+00	741.00
IUUC-Cfa-020799	Canis familiaris	97.52	0.00e+00	635.00
IUUC-Cpo-022093	Cavia porcellus	97.00	4.00e-174	604.00
IUUC-Cre-022634	Chlamydomonas reinhardtii	48.15	2.00e-11	62.80
IUUC-Csa-023627	Chlorocebus sabaeus	99.66	0.00e+00	757.00
IUUC-Cho-024552	Choloepus hoffmanni	92.81	6.00e-174	603.00
IUUC-Csv-026009	Ciona savignyi	48.84	2.00e-88	319.00
IUUC-Cne-026833	Cryptococcus neoformans	27.47	2.00e-13	70.10
IUUC-Dno-029647	Dasypus novemcinctus	94.26	0.00e+00	629.00
IUUC-Ete-033071	Echinops telfairi	88.01	0.00e+00	734.00
IUUC-Eeu-034727	Erinaceus europaeus	94.32	0.00e+00	712.00
IUUC-Fca-035803	Felis catus	97.97	2.00e-179	622.00
IUUC-Fso-038204	Fusarium solani	40.85	1.00e-07	50.80
IUUC-Hsa-046768	Homo sapiens	100.00	1.00e-178	619.00
IUUC-Hvu-047094	Hordeum vulgare	50.98	3.00e-09	53.50
IUUC-Itr-048556	Ictidomys tridecemlineatus	92.15	1.00e-173	603.00
IUUC-Mmr-061605	Microcebus murinus	97.74	6.00e-172	597.00
IUUC-Mpu-066474	Mustela putorius furo	97.52	2.00e-179	622.00
IUUC-Mlu-067252	Myotis lucifugus	87.19	1.00e-163	569.00
IUUC-Nle-069038	Nomascus leucogenys	99.83	0.00e+00	758.00
IUUC-Oga-088005	Otolemur garnettii	98.87	2.00e-178	619.00
IUUC-Oar-089878	Ovis aries	97.24	0.00e+00	751.00
IUUC-Pan-091716	Papio anubis	92.93	0.00e+00	694.00
IUUC-Pab-097891	Pongo abelii	99.77	5.00e-179	620.00
IUUC-Pca-100227	Procavia capensis	96.62	2.00e-95	343.00
IUUC-Pgr-103261	Puccinia graminis	54.76	2.00e-07	50.10
IUUC-Sce-106332	Saccharomyces cerevisiae	44.16	8.00e-11	61.20
IUUC-Spo-108223	Schizosaccharomyces pombe	27.48	2.00e-10	59.70
IUUC-Sre-115081	Sporisorium reilianum	26.52	4.00e-11	62.40
IUUC-Tsy-119008	Tarsius syrichta	96.06	2.00e-172	598.00
IUUC-Uma-129639	Ustilago maydis	27.16	6.00e-11	61.60

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence