iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNA	TRANSFAC	RAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	70.24	0.00e+00	912.00	IUUC-Hsa-046776

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MLRGGCKASE KRRHLSESLS WQQDQALSSS IYLLRQIGPT GFLLREEEPE NGDFRVLLGN 60
PHECSCPTFL KRGELCKHIC WVLLKKFKLP RNHESAFQLG LTEGEINDLL RGIHQVQTPQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGAGACCCCA GGCGCCTCTG AAAGCTTAAC GTAGAGGCGC CACGGCCGCC AGGGATGCTT 60
CGCGGAGGCT GTAAAGCCTC CGAAAAGCGA AGACACTTAA GCGAGAGCCT CAGCTGGCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR007527--Znf_SWIM
IPR000433--Znf_ZZ

PROSITE

PS50089--ZF_RING_2
PS50966--ZF_SWIM
PS01357--ZF_ZZ_1
PS50135--ZF_ZZ_2

Pfam

PF04434--SWIM
PF13639--zf-RING_2
PF00569--ZZ

SMART

SM00184--RING
SM00291--ZnF_ZZ

Gene Ontology

GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:1902043--P:positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:0000209--P:protein polyubiquitination

KEGG

rno:296455

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001754	Ailuropoda melanoleuca	72.96	0.00e+00	939.00
IUUC-Apl-003359	Anas platyrhynchos	56.92	8.00e-42	162.00
IUUC-Aca-004923	Anolis carolinensis	55.84	1.00e-118	419.00
IUUC-Afl-008716	Aspergillus flavus	29.45	5.00e-14	72.00
IUUC-Ani-009202	Aspergillus nidulans	30.82	4.00e-12	65.50
IUUC-Bta-012456	Bos taurus	67.40	0.00e+00	885.00
IUUC-Cja-019186	Callithrix jacchus	68.35	0.00e+00	859.00
IUUC-Cfa-020604	Canis familiaris	69.88	0.00e+00	834.00
IUUC-Cpo-021774	Cavia porcellus	66.77	0.00e+00	846.00
IUUC-Cre-022861	Chlamydomonas reinhardtii	32.93	6.00e-30	125.00
IUUC-Csa-024126	Chlorocebus sabaeus	69.92	0.00e+00	883.00
IUUC-Cho-024501	Choloepus hoffmanni	74.86	3.00e-165	574.00
IUUC-Cin-025662	Ciona intestinalis	43.24	6.00e-96	344.00
IUUC-Cgl-026506	Colletotrichum gloeosporioides	27.47	4.00e-09	55.50
IUUC-Cne-027076	Cryptococcus neoformans	25.11	9.00e-12	65.10
IUUC-Dre-028700	Danio rerio	40.35	6.00e-110	391.00
IUUC-Dno-030007	Dasypus novemcinctus	68.55	0.00e+00	899.00
IUUC-Dor-030562	Dipodomys ordii	59.34	0.00e+00	681.00
IUUC-Dse-031237	Dothistroma septosporum	27.78	1.00e-09	57.40
IUUC-Ete-032603	Echinops telfairi	68.97	3.00e-140	491.00
IUUC-Eca-033283	Equus caballus	70.86	0.00e+00	901.00
IUUC-Eeu-034619	Erinaceus europaeus	61.79	0.00e+00	783.00
IUUC-Fca-035573	Felis catus	71.65	0.00e+00	941.00
IUUC-Fso-038137	Fusarium solani	25.54	6.00e-11	61.60
IUUC-Ggo-045207	Gorilla gorilla	69.92	0.00e+00	890.00
IUUC-Hsa-046776	Homo sapiens	70.24	0.00e+00	889.00
IUUC-Itr-048416	Ictidomys tridecemlineatus	71.38	0.00e+00	925.00
IUUC-Lch-050394	Latimeria chalumnae	42.33	1.00e-136	480.00
IUUC-Loc-052123	Lepisosteus oculatus	50.57	4.00e-131	461.00
IUUC-Lma-053033	Leptosphaeria maculans	33.11	4.00e-12	65.50
IUUC-Laf-053456	Loxodonta africana	68.24	0.00e+00	873.00
IUUC-Mcc-055227	Macaca mulatta	70.08	0.00e+00	887.00
IUUC-Meu-055957	Macropus eugenii	60.08	6.00e-90	324.00
IUUC-Mmr-061710	Microcebus murinus	71.07	0.00e+00	913.00
IUUC-Mdo-062378	Monodelphis domestica	54.66	0.00e+00	663.00
IUUC-Mmu-064269	Mus musculus	89.22	0.00e+00	1171.00
IUUC-Mpu-066736	Mustela putorius furo	67.62	0.00e+00	822.00
IUUC-Mlu-067142	Myotis lucifugus	58.42	0.00e+00	698.00
IUUC-Nfi-068477	Neosartorya fischeri	30.00	5.00e-12	65.10
IUUC-Ncr-068657	Neurospora crassa	28.86	5.00e-10	58.20
IUUC-Nle-069268	Nomascus leucogenys	70.55	0.00e+00	909.00
IUUC-Opr-071154	Ochotona princeps	60.68	7.00e-145	507.00
IUUC-Oan-072878	Ornithorhynchus anatinus	39.02	9.00e-50	190.00
IUUC-Ocu-074017	Oryctolagus cuniculus	68.90	0.00e+00	822.00
IUUC-Oga-088906	Otolemur garnettii	67.67	0.00e+00	878.00
IUUC-Oar-089422	Ovis aries	68.03	0.00e+00	898.00
IUUC-Ptr-090772	Pan troglodytes	69.92	0.00e+00	885.00
IUUC-Pan-092838	Papio anubis	69.29	0.00e+00	858.00
IUUC-Psi-093288	Pelodiscus sinensis	51.42	2.00e-139	488.00
IUUC-Pma-094709	Petromyzon marinus	45.77	4.00e-103	367.00
IUUC-Pfo-096189	Poecilia formosa	40.24	1.00e-91	330.00
IUUC-Pab-098389	Pongo abelii	65.51	0.00e+00	807.00
IUUC-Pca-100376	Procavia capensis	60.25	0.00e+00	731.00
IUUC-Pva-102163	Pteropus vampyrus	68.71	0.00e+00	867.00
IUUC-Pte-104391	Pyrenophora teres	31.48	2.00e-13	69.30
IUUC-Pyt-104706	Pyrenophora triticirepentis	30.87	2.00e-13	69.70
IUUC-Sha-107063	Sarcophilus harrisii	54.21	0.00e+00	650.00
IUUC-Sar-113069	Sorex araneus	63.56	0.00e+00	821.00
IUUC-Ssc-116112	Sus scrofa	68.08	0.00e+00	848.00
IUUC-Tsy-118825	Tarsius syrichta	74.21	0.00e+00	767.00
IUUC-Tbe-127891	Tupaia belangeri	68.08	0.00e+00	871.00
IUUC-Ttr-129130	Tursiops truncatus	68.29	0.00e+00	754.00
IUUC-Vda-129853	Verticillium dahliae	26.92	5.00e-09	55.50
IUUC-Vpa-130753	Vicugna pacos	69.50	0.00e+00	892.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence