iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Nle-069479

Ensembl Protein ID

ENSNLEP00000023306.1

UniProt Accession

M3Z9B9; M3Z9B9_NOMLE

Genbank Protein ID

ENSNLEP00000023306

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01031854

Gene Name

IFIH1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000026782.1	ENSNLET00000031670.1	ENSNLEP00000023306.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/CARD	6.50e-54	180.4	7	80

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/CARD

   S: 1    tdeeyrlllstlqdrvrklLdvtdvldkylseflleeekelilaaaetkgnmqaaelLLktL...vqkegWfrefl 73
           tde++r+l+s+++ rv+++++v++vld yl+ fl++e+ke+i+++++t+gnmqa+elLL+tL   v++ gW+ efl
   Q: 7    TDENFRYLISCFRTRVKMYIQVEPVLD-YLT-FLPAEVKEQIQRTVATSGNMQAVELLLSTLekgVWHIGWTGEFL 80
           69*************************.***.****************************************9996 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MSNGYSTDEN FRYLISCFRT RVKMYIQVEP VLDYLTFLPA EVKEQIQRTV ATSGNMQAVE 60
LLLSTLEKGV WHIGWTGEFL EALRRTGSPL AARYMNPELT DLPSPSFENA HDECLQLLNL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCGAATG GGTATTCCAC AGACGAGAAT TTCCGCTATC TCATCTCGTG CTTCAGGACC 60
AGAGTGAAAA TGTACATCCA GGTGGAGCCT GTGCTGGATT ACCTGACCTT TCTGCCTGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0862--Zinc

Interpro

IPR031964--CARD_dom
IPR011029--DEATH-like_dom
IPR006935--Helicase/UvrB_N
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR021673--RLR_CTR

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS51789--RLR_CTR

Pfam

PF16739--CARD_2
PF00271--Helicase_C
PF04851--ResIII
PF11648--RIG-I_C-RD

SMART

SM00487--DEXDc
SM00490--HELICc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0003677--F:DNA binding
GO:0003725--F:double-stranded RNA binding
GO:0016817--F:hydrolase activity, acting on acid anhydrides
GO:0043021--F:ribonucleoprotein complex binding
GO:0003727--F:single-stranded RNA binding
GO:0008270--F:zinc ion binding
GO:0039530--P:MDA-5 signaling pathway
GO:0032727--P:positive regulation of interferon-alpha production
GO:0032728--P:positive regulation of interferon-beta production
GO:0016925--P:protein sumoylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001336	Ailuropoda melanoleuca	81.91	0.00e+00	1588.00
IUUC-Apl-003900	Anas platyrhynchos	61.15	0.00e+00	1191.00
IUUC-Aca-005329	Anolis carolinensis	58.90	0.00e+00	1018.00
IUUC-Ame-011305	Astyanax mexicanus	55.63	0.00e+00	783.00
IUUC-Bta-012361	Bos taurus	80.84	0.00e+00	1529.00
IUUC-Cel-018230	Caenorhabditis elegans	31.15	1.00e-32	135.00
IUUC-Cja-018760	Callithrix jacchus	88.49	0.00e+00	1669.00
IUUC-Cfa-020321	Canis familiaris	79.96	0.00e+00	1515.00
IUUC-Cpo-022450	Cavia porcellus	77.80	0.00e+00	1523.00
IUUC-Cre-022916	Chlamydomonas reinhardtii	33.33	2.00e-12	68.60
IUUC-Csa-024194	Chlorocebus sabaeus	93.56	0.00e+00	1721.00
IUUC-Cho-024364	Choloepus hoffmanni	72.39	0.00e+00	1009.00
IUUC-Cin-025792	Ciona intestinalis	30.88	1.00e-70	260.00
IUUC-Cgl-026385	Colletotrichum gloeosporioides	31.34	1.00e-14	75.90
IUUC-Dre-028305	Danio rerio	48.26	0.00e+00	793.00
IUUC-Dno-029831	Dasypus novemcinctus	83.32	0.00e+00	1612.00
IUUC-Dor-030410	Dipodomys ordii	87.15	0.00e+00	1099.00
IUUC-Ete-032950	Echinops telfairi	68.08	0.00e+00	778.00
IUUC-Eca-034279	Equus caballus	84.60	0.00e+00	1604.00
IUUC-Eeu-034678	Erinaceus europaeus	79.63	0.00e+00	1562.00
IUUC-Fca-035618	Felis catus	88.22	0.00e+00	986.00
IUUC-Fal-037106	Ficedula albicollis	69.53	0.00e+00	987.00
IUUC-Fso-038398	Fusarium solani	33.33	4.00e-16	80.90
IUUC-Gmo-038598	Gadus morhua	49.51	0.00e+00	675.00
IUUC-Gga-040467	Gallus gallus	61.08	0.00e+00	1169.00
IUUC-Gac-042316	Gasterosteus aculeatus	54.51	0.00e+00	755.00
IUUC-Ggo-045461	Gorilla gorilla	93.56	0.00e+00	1720.00
IUUC-Hsa-045771	Homo sapiens	93.66	0.00e+00	1720.00
IUUC-Itr-048762	Ictidomys tridecemlineatus	83.12	0.00e+00	1566.00
IUUC-Lch-049913	Latimeria chalumnae	66.26	0.00e+00	930.00
IUUC-Loc-052768	Lepisosteus oculatus	53.57	0.00e+00	988.00
IUUC-Laf-053933	Loxodonta africana	81.42	0.00e+00	1560.00
IUUC-Mcc-054695	Macaca mulatta	93.76	0.00e+00	1727.00
IUUC-Meu-056829	Macropus eugenii	74.29	0.00e+00	1123.00
IUUC-Mga-059205	Meleagris gallopavo	61.00	0.00e+00	1172.00
IUUC-Mvi-060497	Microbotryum violaceum	33.33	4.00e-17	84.30
IUUC-Mmr-060703	Microcebus murinus	85.53	0.00e+00	1600.00
IUUC-Mdo-063079	Monodelphis domestica	72.42	0.00e+00	1444.00
IUUC-Mmu-064066	Mus musculus	77.49	0.00e+00	1583.00
IUUC-Mpu-066261	Mustela putorius furo	81.58	0.00e+00	1551.00
IUUC-Mlu-068196	Myotis lucifugus	80.35	0.00e+00	1526.00
IUUC-Nfi-068405	Neosartorya fischeri	23.59	9.00e-23	103.00
IUUC-Opr-070717	Ochotona princeps	73.54	0.00e+00	1135.00
IUUC-Ont-071702	Oreochromis niloticus	54.65	0.00e+00	747.00
IUUC-Oan-073639	Ornithorhynchus anatinus	65.25	0.00e+00	1172.00
IUUC-Ocu-074521	Oryctolagus cuniculus	82.63	0.00e+00	1614.00
IUUC-Ola-086351	Oryzias latipes	52.37	0.00e+00	700.00
IUUC-Oga-088539	Otolemur garnettii	82.93	0.00e+00	1564.00
IUUC-Oar-090186	Ovis aries	80.65	0.00e+00	1520.00
IUUC-Ptr-090575	Pan troglodytes	98.57	0.00e+00	1747.00
IUUC-Pan-092371	Papio anubis	93.46	0.00e+00	1719.00
IUUC-Psi-093072	Pelodiscus sinensis	61.26	0.00e+00	1176.00
IUUC-Pma-094345	Petromyzon marinus	43.39	4.00e-97	348.00
IUUC-Pfo-096401	Poecilia formosa	45.67	0.00e+00	759.00
IUUC-Pab-097623	Pongo abelii	91.80	0.00e+00	1736.00
IUUC-Pca-100993	Procavia capensis	75.40	0.00e+00	1263.00
IUUC-Pva-102227	Pteropus vampyrus	78.83	0.00e+00	1448.00
IUUC-Pgr-103529	Puccinia graminis	34.73	1.00e-16	82.80
IUUC-Rno-105198	Rattus norvegicus	77.51	0.00e+00	1573.00
IUUC-Sha-107622	Sarcophilus harrisii	72.00	0.00e+00	1418.00
IUUC-Ssl-108450	Sclerotinia sclerotiorum	32.35	2.70e-02	35.80
IUUC-Sar-113625	Sorex araneus	87.01	1.00e-164	573.00
IUUC-Ssc-116120	Sus scrofa	33.20	1.00e-83	304.00
IUUC-Tgu-117486	Taeniopygia guttata	60.45	0.00e+00	1142.00
IUUC-Tru-118445	Takifugu rubripes	45.36	0.00e+00	815.00
IUUC-Tsy-119512	Tarsius syrichta	87.71	0.00e+00	1586.00
IUUC-Tni-120711	Tetraodon nigroviridis	44.49	0.00e+00	829.00
IUUC-Tre-122194	Trichoderma reesei	31.54	2.00e-13	72.00
IUUC-Tbe-127644	Tupaia belangeri	74.44	0.00e+00	1383.00
IUUC-Ttr-128989	Tursiops truncatus	78.16	0.00e+00	1535.00
IUUC-Vpa-130587	Vicugna pacos	76.26	0.00e+00	1219.00
IUUC-Xtr-132127	Xenopus tropicalis	53.24	0.00e+00	1013.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence