iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ggo-045236

Ensembl Protein ID

ENSGGOP00000027386.1

UniProt Accession

G3SGZ9; G3SGZ9_GORGO

Protein Name

Uncharacterized protein

Gene Name

NPLOC4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000004220.2	ENSGGOT00000023679.1	ENSGGOP00000027386.1
ENSGGOG00000004220.2	ENSGGOT00000004242.2	ENSGGOP00000004140.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/ZnF/NZF	1.40e-12	47.3	580	607

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/ZnF/NZF

   S: 2    eaqWaCsaCTflNePeavkCemCsrpRg 29
           +a+WaC++CTf+N+P +++CemCs pR+
   Q: 580  AAMWACQHCTFMNQPGTGHCEMCSLPRT 607
           689***********************95 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MFCLQQIIRV QSPDGVKRIT ATKRETAATF LKKVAKEFGF QNNGFSVYIN RNKTGEITAS 60
SNKSLNLLKI KHGDLLFLFP SSLAGPSSEM ETSAPLGFKV FGAPNVVEDE IDQYLSKQDG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAAGCCG TAGTATTAGA TCAGGACCTC ACTAGGCTGT GCAGTAACCT TCATGTTTTG 60
TTTGCAACAG ATAATTCGTG TCCAGTCCCC GGATGGAGTG AAGCGGATCA CAGCAACAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome

Interpro

IPR016563--Npl4
IPR007717--NPL4_C
IPR024682--Npl4_Ub-like_dom
IPR007716--NPL4_Zn-bd_put
IPR029071--Ubiquitin-rel_dom
IPR001876--Znf_RanBP2

PROSITE

PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2

Pfam

PF05021--NPL4
PF11543--UN_NPL4
PF05020--zf-NPL4

SMART

SM00547--ZnF_RBZ

Gene Ontology

GO:0005634--C:nucleus
GO:0036501--C:UFD1-NPL4 complex
GO:0034098--C:VCP-NPL4-UFD1 AAA ATPase complex
GO:0008270--F:zinc ion binding
GO:0039536--P:negative regulation of RIG-I signaling pathway
GO:0032480--P:negative regulation of type I interferon production
GO:0030970--P:retrograde protein transport, ER to cytosol
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000460	Aegilops tauschii	27.78	6.00e-12	65.50
IUUC-Aml-002268	Ailuropoda melanoleuca	93.37	0.00e+00	1148.00
IUUC-Atr-002939	Amborella trichopoda	27.14	1.00e-13	70.90
IUUC-Apl-003496	Anas platyrhynchos	85.25	0.00e+00	1025.00
IUUC-Aca-005230	Anolis carolinensis	87.25	0.00e+00	1100.00
IUUC-Aly-006056	Arabidopsis lyrata	29.41	2.00e-18	87.00
IUUC-Ath-006993	Arabidopsis thaliana	26.55	3.00e-16	79.70
IUUC-Ago-007954	Ashbya gossypii	35.71	5.00e-72	265.00
IUUC-Acl-008208	Aspergillus clavatus	32.75	3.00e-83	302.00
IUUC-Afl-008574	Aspergillus flavus	34.84	3.00e-82	299.00
IUUC-Afu-008825	Aspergillus fumigatus	33.39	4.00e-90	325.00
IUUC-Ani-009495	Aspergillus nidulans	38.22	1.00e-86	313.00
IUUC-Ang-009762	Aspergillus niger	32.95	1.00e-81	297.00
IUUC-Aor-010199	Aspergillus oryzae	34.30	2.00e-80	293.00
IUUC-Ate-010592	Aspergillus terreus	35.84	4.00e-85	308.00
IUUC-Ame-011587	Astyanax mexicanus	72.58	5.00e-104	371.00
IUUC-Bgr-012124	Blumeria graminis	32.09	3.00e-82	299.00
IUUC-Bta-013312	Bos taurus	93.86	0.00e+00	1181.00
IUUC-Bci-013648	Botrytis cinerea	33.16	2.00e-88	319.00
IUUC-Bdi-014326	Brachypodium distachyon	28.10	5.00e-13	68.90
IUUC-Bol-016294	Brassica oleracea	27.73	3.00e-16	79.30
IUUC-Bra-017023	Brassica rapa	27.62	4.00e-16	79.30
IUUC-Cel-018713	Caenorhabditis elegans	41.51	2.00e-119	422.00
IUUC-Cja-018869	Callithrix jacchus	95.36	0.00e+00	1165.00
IUUC-Cfa-020757	Canis familiaris	94.36	0.00e+00	1167.00
IUUC-Cpo-022390	Cavia porcellus	93.91	0.00e+00	1157.00
IUUC-Csa-023366	Chlorocebus sabaeus	96.19	0.00e+00	1204.00
IUUC-Cho-024455	Choloepus hoffmanni	75.33	0.00e+00	791.00
IUUC-Cin-025638	Ciona intestinalis	46.67	9.00e-136	476.00
IUUC-Csv-026310	Ciona savignyi	44.12	9.00e-124	437.00
IUUC-Cgl-026685	Colletotrichum gloeosporioides	32.95	7.00e-84	304.00
IUUC-Cne-026794	Cryptococcus neoformans	28.04	1.00e-64	241.00
IUUC-Cme-027248	Cyanidioschyzon merolae	25.62	1.00e-11	64.70
IUUC-Dre-027689	Danio rerio	78.14	0.00e+00	994.00
IUUC-Dno-030004	Dasypus novemcinctus	92.87	0.00e+00	1155.00
IUUC-Dor-030585	Dipodomys ordii	92.20	0.00e+00	926.00
IUUC-Dse-031202	Dothistroma septosporum	32.16	2.00e-81	296.00
IUUC-Dme-032092	Drosophila melanogaster	46.59	9.00e-167	580.00
IUUC-Ete-033009	Echinops telfairi	94.74	8.00e-94	337.00
IUUC-Eca-034001	Equus caballus	94.53	0.00e+00	1191.00
IUUC-Eeu-034485	Erinaceus europaeus	77.33	0.00e+00	783.00
IUUC-Fca-036128	Felis catus	93.70	0.00e+00	1123.00
IUUC-Fal-037523	Ficedula albicollis	87.42	0.00e+00	1105.00
IUUC-Fox-037802	Fusarium oxysporum	33.56	5.00e-88	318.00
IUUC-Fso-038152	Fusarium solani	33.44	7.00e-89	321.00
IUUC-Gmo-038486	Gadus morhua	72.44	0.00e+00	902.00
IUUC-Ggr-039916	Gaeumannomyces graminis	36.19	4.00e-79	289.00
IUUC-Gga-041208	Gallus gallus	88.74	0.00e+00	1126.00
IUUC-Gac-042304	Gasterosteus aculeatus	75.24	0.00e+00	930.00
IUUC-Gma-044178	Glycine max	25.49	1.00e-10	60.80
IUUC-Hsa-046334	Homo sapiens	96.19	0.00e+00	1205.00
IUUC-Hvu-047323	Hordeum vulgare	24.77	4.00e-04	37.70
IUUC-Itr-047878	Ictidomys tridecemlineatus	92.14	0.00e+00	676.00
IUUC-Lch-050302	Latimeria chalumnae	80.36	0.00e+00	1007.00
IUUC-Lpe-051362	Leersia perrieri	28.31	5.00e-15	75.10
IUUC-Loc-052548	Lepisosteus oculatus	79.77	0.00e+00	976.00
IUUC-Lma-053092	Leptosphaeria maculans	33.22	2.00e-89	323.00
IUUC-Laf-053911	Loxodonta africana	93.38	0.00e+00	1172.00
IUUC-Mcc-055830	Macaca mulatta	95.71	0.00e+00	1199.00
IUUC-Meu-056460	Macropus eugenii	58.10	1.00e-147	516.00
IUUC-Mor-057189	Magnaporthe oryzae	36.12	8.00e-82	298.00
IUUC-Mpo-057366	Magnaporthe poae	31.59	1.00e-79	290.00
IUUC-Mtr-057834	Medicago truncatula	25.44	2.00e-12	66.60
IUUC-Mla-059190	Melampsora laricipopulina	31.38	2.00e-77	283.00
IUUC-Mga-060036	Meleagris gallopavo	88.43	0.00e+00	1122.00
IUUC-Mvi-060275	Microbotryum violaceum	28.94	4.00e-73	269.00
IUUC-Mmr-061300	Microcebus murinus	94.42	0.00e+00	1193.00
IUUC-Mdo-062911	Monodelphis domestica	92.26	0.00e+00	994.00
IUUC-Mmu-063916	Mus musculus	93.86	0.00e+00	1157.00
IUUC-Mac-065601	Musa acuminata	25.73	2.00e-09	56.60
IUUC-Mpu-065912	Mustela putorius furo	93.37	0.00e+00	1154.00
IUUC-Mlu-067965	Myotis lucifugus	92.04	0.00e+00	1134.00
IUUC-Nfi-068465	Neosartorya fischeri	33.55	2.00e-90	326.00
IUUC-Ncr-068936	Neurospora crassa	32.23	3.00e-85	309.00
IUUC-Nle-069570	Nomascus leucogenys	95.69	0.00e+00	1194.00
IUUC-Opr-071097	Ochotona princeps	87.89	0.00e+00	868.00
IUUC-Ont-071430	Oreochromis niloticus	76.81	0.00e+00	974.00
IUUC-Oan-073709	Ornithorhynchus anatinus	78.56	0.00e+00	738.00
IUUC-Ocu-074875	Oryctolagus cuniculus	88.18	0.00e+00	1097.00
IUUC-Oba-075214	Oryza barthii	28.06	2.00e-14	73.60
IUUC-Obr-076758	Oryza brachyantha	28.15	1.00e-14	73.60
IUUC-Ogl-077665	Oryza glaberrima	28.06	2.00e-14	73.60
IUUC-Ogu-078899	Oryza glumaepatula	28.06	2.00e-14	73.60
IUUC-Oin-079167	Oryza indica	28.06	2.00e-14	73.60
IUUC-Olo-080451	Oryza longistaminata	28.57	1.00e-14	73.60
IUUC-Ome-081836	Oryza meridionalis	28.06	2.00e-14	73.60
IUUC-Oni-083019	Oryza nivara	28.06	2.00e-14	73.60
IUUC-Opu-083122	Oryza punctata	28.62	8.00e-15	74.70
IUUC-Oru-084900	Oryza rufipogon	28.06	2.00e-14	73.60
IUUC-Osa-086054	Oryza sativa	28.06	2.00e-14	73.60
IUUC-Ola-087077	Oryzias latipes	66.61	0.00e+00	808.00
IUUC-Olu-087601	Ostreococcus lucimarinus	26.27	9.00e-05	41.20
IUUC-Oga-088049	Otolemur garnettii	80.36	0.00e+00	989.00
IUUC-Oar-089678	Ovis aries	93.86	0.00e+00	1182.00
IUUC-Ptr-091380	Pan troglodytes	95.17	0.00e+00	1093.00
IUUC-Pan-092821	Papio anubis	94.55	0.00e+00	1188.00
IUUC-Psi-093074	Pelodiscus sinensis	89.09	0.00e+00	1119.00
IUUC-Pma-094102	Petromyzon marinus	66.67	0.00e+00	854.00
IUUC-Pno-094987	Phaeosphaeria nodorum	33.33	1.00e-85	311.00
IUUC-Ppa-095368	Physcomitrella patens	27.16	2.00e-13	69.30
IUUC-Pfo-097245	Poecilia formosa	78.38	0.00e+00	952.00
IUUC-Pab-098763	Pongo abelii	96.06	0.00e+00	1215.00
IUUC-Pop-099355	Populus trichocarpa	29.02	6.00e-10	58.20
IUUC-Ppe-101990	Prunus persica	26.43	1.00e-12	67.40
IUUC-Pva-102308	Pteropus vampyrus	84.57	0.00e+00	907.00
IUUC-Pgr-103553	Puccinia graminis	31.52	3.00e-74	273.00
IUUC-Pte-104100	Pyrenophora teres	31.46	3.00e-82	299.00
IUUC-Pyt-104482	Pyrenophora triticirepentis	33.11	1.00e-83	304.00
IUUC-Rno-105582	Rattus norvegicus	93.53	0.00e+00	1152.00
IUUC-Sce-106145	Saccharomyces cerevisiae	33.11	2.00e-84	306.00
IUUC-Sha-106647	Sarcophilus harrisii	91.54	0.00e+00	1136.00
IUUC-Sja-107972	Schizosaccharomyces japonicus	34.27	5.00e-78	285.00
IUUC-Spo-108281	Schizosaccharomyces pombe	33.62	5.00e-84	305.00
IUUC-Ssl-108617	Sclerotinia sclerotiorum	38.06	6.00e-85	308.00
IUUC-Smo-108933	Selaginella moellendorffii	29.39	5.00e-15	75.10
IUUC-Sit-110083	Setaria italica	27.86	2.00e-13	69.70
IUUC-Sly-111645	Solanum lycopersicum	24.67	3.00e-11	62.80
IUUC-Stu-112422	Solanum tuberosum	24.67	2.00e-11	63.50
IUUC-Sbi-113987	Sorghum bicolor	28.68	3.00e-14	72.80
IUUC-Sre-115095	Sporisorium reilianum	36.48	2.00e-74	273.00
IUUC-Ssc-116141	Sus scrofa	92.02	0.00e+00	1045.00
IUUC-Tgu-117492	Taeniopygia guttata	86.19	0.00e+00	807.00
IUUC-Tru-118463	Takifugu rubripes	75.85	0.00e+00	932.00
IUUC-Tsy-118993	Tarsius syrichta	85.69	0.00e+00	959.00
IUUC-Tni-119896	Tetraodon nigroviridis	77.48	0.00e+00	933.00
IUUC-Tca-121169	Theobroma cacao	27.33	7.00e-15	74.70
IUUC-Tre-122046	Trichoderma reesei	32.39	6.00e-86	311.00
IUUC-Tvi-122415	Trichoderma virens	33.44	4.00e-87	315.00
IUUC-Tae-123514	Triticum aestivum	27.78	5.00e-12	65.50
IUUC-Tme-127123	Tuber melanosporum	34.77	4.00e-94	338.00
IUUC-Tbe-127629	Tupaia belangeri	91.72	3.00e-156	545.00
IUUC-Ttr-128476	Tursiops truncatus	83.15	0.00e+00	921.00
IUUC-Uma-129492	Ustilago maydis	34.39	2.00e-77	283.00
IUUC-Vda-129702	Verticillium dahliae	33.10	9.00e-83	301.00
IUUC-Vvi-131090	Vitis vinifera	28.12	1.00e-08	54.30
IUUC-Xtr-131786	Xenopus tropicalis	82.43	0.00e+00	1024.00
IUUC-Xma-133997	Xiphophorus maculatus	75.92	0.00e+00	947.00
IUUC-Yli-134537	Yarrowia lipolytica	34.10	1.00e-82	300.00
IUUC-Zma-134847	Zea mays	29.47	2.00e-15	77.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence