iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pfo-096493

Ensembl Protein ID

ENSPFOP00000009875.2

UniProt Accession

A0A087XVS2; A0A087XVS2_POEFO

Genbank Protein ID

ENSPFOP00000009875

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AYCK01003575

Gene Name

FBXW7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPFOG00000009723.2	ENSPFOT00000009890.2	ENSPFOP00000009875.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.80e-61	200.2	468	501
UBD/Beta-Prp	8.50e-103	344.2	219	501

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    HtdsvtclafsdtllvsGsdDgtikvWDlrtgvl 35
           H++ vtcl+f+ ++++++sdDgt+k+WDl+tg  
   Q: 468  HQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEF 501
           9*********449******************976 PP

UBD/Beta-Prp

   S: 3    ktlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlk 91
           k+lkgh+++vitc++f   ++ +++gs+d+t+kvw++ tgk+lr+l gh+++v++ ++ ++  i+++gs+Drt+kvw+ +tg+c+htl 
   Q: 219  KVLKGHDDHVITCLQF--CGNRIVSGSDDNTLKVWSAITGKCLRTLVGHTGGVWSSQMRDN--IIISGSTDRTLKVWNAETGECIHTLY 303
           6799************..*******************************************..************************** PP
   S: 92   ghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgght 180
           gh+++v+++++++  +++vsGs+d t+rvwd+etgqcl+ +l gh ++v+cv++++  + +vsG++D +v++Wd +t+++l+tl+g ht
   Q: 304  GHTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLH-VLMGHVAAVRCVQYDG--RRVVSGAYDFMVKVWDPETETCLHTLQG-HT 386
           *************..************************.****************..***************************9.** PP
   S: 181  dsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvis 269
           ++vysl+fd    ++vsgsld+++++wd++tg+c++tl+gh++ ++ +++   d++lvsg++D +++iWd+++g++l+tlq+++++ ++
   Q: 387  NRVYSLQFDG--IHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELK--DNILVSGNADSTVKIWDIKTGQCLQTLQGPHKHQSA 471
           *********9..9**************************************..************************************ PP
   S: 270  vavlsfgdnvlvlgsedskvniwklkknep 299
           v++l+f++n +++ s+d++v++w+lk+ e+
   Q: 472  VTCLQFNKNFVITSSDDGTVKLWDLKTGEF 501
           *************************98776 PP

Organism

Poecilia formosa

Protein Sequence
(Fasta)

MSPFFRLDGN MKMKRKLDHG PEVRSFPSGK KPCKGPEYPS PTGIVPCPAT PTTFGHIRAA 60
NGQGQQRRRI TSIQPPTGLQ EWLRTFQSWS GPEKLLALDE LIDSCEPTQV KHMMQVIEPQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCTCCTT TCTTCCGGTT GGACGGGAAC ATGAAGGTAA GAAAAAGTTT TGTTTTCCTG 60
TAAATGCTCA TGCTGTGGTT TCCTTTCTCT TTTCTAATCC TTTATTCTGA ACCACATTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR001810--F-box_dom
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50181--FBOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12937--F-box-like
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00256--FBOX
SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002406	Ailuropoda melanoleuca	94.01	0.00e+00	1055.00
IUUC-Apl-003489	Anas platyrhynchos	94.19	0.00e+00	1056.00
IUUC-Aca-005318	Anolis carolinensis	95.56	0.00e+00	1053.00
IUUC-Ago-007794	Ashbya gossypii	30.86	1.00e-60	227.00
IUUC-Acl-008123	Aspergillus clavatus	33.20	1.00e-74	274.00
IUUC-Afl-008730	Aspergillus flavus	31.88	7.00e-73	268.00
IUUC-Afu-009014	Aspergillus fumigatus	32.73	5.00e-74	272.00
IUUC-Ani-009332	Aspergillus nidulans	32.80	5.00e-79	288.00
IUUC-Ang-009529	Aspergillus niger	33.40	3.00e-74	273.00
IUUC-Aor-010215	Aspergillus oryzae	30.91	1.00e-72	267.00
IUUC-Ate-010535	Aspergillus terreus	32.54	2.00e-75	276.00
IUUC-Ame-010898	Astyanax mexicanus	94.91	0.00e+00	1053.00
IUUC-Bgr-012075	Blumeria graminis	33.47	3.00e-79	289.00
IUUC-Bta-012391	Bos taurus	95.56	0.00e+00	1052.00
IUUC-Cel-018495	Caenorhabditis elegans	48.53	1.00e-130	460.00
IUUC-Cja-018902	Callithrix jacchus	94.37	0.00e+00	1058.00
IUUC-Cfa-020237	Canis familiaris	94.37	0.00e+00	1057.00
IUUC-Cpo-022234	Cavia porcellus	95.56	0.00e+00	1055.00
IUUC-Cre-022837	Chlamydomonas reinhardtii	37.42	1.00e-48	187.00
IUUC-Csa-023532	Chlorocebus sabaeus	94.37	0.00e+00	1058.00
IUUC-Cho-025026	Choloepus hoffmanni	77.71	0.00e+00	697.00
IUUC-Cin-025516	Ciona intestinalis	70.99	3.00e-140	491.00
IUUC-Csv-026312	Ciona savignyi	74.84	0.00e+00	747.00
IUUC-Cgl-026492	Colletotrichum gloeosporioides	35.22	8.00e-86	311.00
IUUC-Cne-027018	Cryptococcus neoformans	32.89	6.00e-72	266.00
IUUC-Cme-027168	Cyanidioschyzon merolae	31.10	2.00e-30	127.00
IUUC-Dre-028303	Danio rerio	94.09	0.00e+00	1041.00
IUUC-Dno-029576	Dasypus novemcinctus	92.38	0.00e+00	1040.00
IUUC-Dor-030196	Dipodomys ordii	92.92	0.00e+00	1033.00
IUUC-Dse-031558	Dothistroma septosporum	39.27	2.00e-70	260.00
IUUC-Dme-031702	Drosophila melanogaster	73.37	0.00e+00	796.00
IUUC-Ete-032791	Echinops telfairi	87.96	0.00e+00	967.00
IUUC-Eca-033424	Equus caballus	95.56	0.00e+00	1053.00
IUUC-Eeu-034996	Erinaceus europaeus	91.47	0.00e+00	1023.00
IUUC-Fca-036422	Felis catus	94.37	0.00e+00	1059.00
IUUC-Fal-037267	Ficedula albicollis	95.01	0.00e+00	1049.00
IUUC-Fox-037800	Fusarium oxysporum	34.61	4.00e-84	305.00
IUUC-Fso-038258	Fusarium solani	34.62	3.00e-84	306.00
IUUC-Gmo-039119	Gadus morhua	87.43	0.00e+00	926.00
IUUC-Ggr-039781	Gaeumannomyces graminis	35.26	4.00e-85	309.00
IUUC-Gga-040667	Gallus gallus	94.19	0.00e+00	1058.00
IUUC-Ggo-044422	Gorilla gorilla	94.37	0.00e+00	1058.00
IUUC-Hsa-045898	Homo sapiens	94.37	0.00e+00	1059.00
IUUC-Itr-048241	Ictidomys tridecemlineatus	98.07	0.00e+00	946.00
IUUC-Kpa-049097	Komagataella pastoris	31.35	3.00e-76	280.00
IUUC-Lch-050414	Latimeria chalumnae	95.42	0.00e+00	1063.00
IUUC-Loc-052348	Lepisosteus oculatus	97.78	0.00e+00	1078.00
IUUC-Lma-053185	Leptosphaeria maculans	32.94	8.00e-73	268.00
IUUC-Laf-054054	Loxodonta africana	94.19	0.00e+00	1058.00
IUUC-Mcc-055056	Macaca mulatta	94.37	0.00e+00	1058.00
IUUC-Meu-056778	Macropus eugenii	92.18	2.00e-167	583.00
IUUC-Mor-057076	Magnaporthe oryzae	34.52	1.00e-84	308.00
IUUC-Mla-059081	Melampsora laricipopulina	34.48	4.00e-81	296.00
IUUC-Mga-059255	Meleagris gallopavo	94.19	0.00e+00	1058.00
IUUC-Mvi-060490	Microbotryum violaceum	38.16	3.00e-66	247.00
IUUC-Mmr-061292	Microcebus murinus	94.37	0.00e+00	1057.00
IUUC-Mdo-062304	Monodelphis domestica	94.37	0.00e+00	1063.00
IUUC-Mmu-063610	Mus musculus	94.01	0.00e+00	1058.00
IUUC-Mpu-065931	Mustela putorius furo	94.37	0.00e+00	1056.00
IUUC-Mlu-066976	Myotis lucifugus	95.38	0.00e+00	1057.00
IUUC-Nfi-068428	Neosartorya fischeri	32.13	2.00e-74	273.00
IUUC-Ncr-068688	Neurospora crassa	36.17	4.00e-87	315.00
IUUC-Nle-070174	Nomascus leucogenys	94.37	0.00e+00	1058.00
IUUC-Opr-070851	Ochotona princeps	80.53	1.00e-175	609.00
IUUC-Ont-071997	Oreochromis niloticus	97.97	0.00e+00	1101.00
IUUC-Oan-072936	Ornithorhynchus anatinus	94.56	0.00e+00	1063.00
IUUC-Ocu-074742	Oryctolagus cuniculus	95.56	0.00e+00	1058.00
IUUC-Obr-076806	Oryza brachyantha	31.52	2.00e-29	125.00
IUUC-Oin-079809	Oryza indica	31.52	2.00e-29	125.00
IUUC-Ola-087098	Oryzias latipes	97.05	0.00e+00	1091.00
IUUC-Olu-087837	Ostreococcus lucimarinus	34.85	1.00e-38	153.00
IUUC-Oga-088884	Otolemur garnettii	97.63	0.00e+00	761.00
IUUC-Oar-090220	Ovis aries	93.51	0.00e+00	1051.00
IUUC-Ptr-090492	Pan troglodytes	94.37	0.00e+00	1059.00
IUUC-Pan-091770	Papio anubis	94.37	0.00e+00	1058.00
IUUC-Psi-093207	Pelodiscus sinensis	95.56	0.00e+00	1053.00
IUUC-Pma-094749	Petromyzon marinus	83.30	0.00e+00	939.00
IUUC-Pno-095026	Phaeosphaeria nodorum	39.10	6.00e-71	262.00
IUUC-Pab-098141	Pongo abelii	95.56	0.00e+00	1053.00
IUUC-Pca-100571	Procavia capensis	92.09	0.00e+00	738.00
IUUC-Pva-102988	Pteropus vampyrus	94.37	0.00e+00	1058.00
IUUC-Pgr-103612	Puccinia graminis	35.48	2.00e-61	230.00
IUUC-Pte-104275	Pyrenophora teres	32.13	1.00e-73	271.00
IUUC-Pyt-104438	Pyrenophora triticirepentis	31.94	2.00e-73	270.00
IUUC-Rno-105706	Rattus norvegicus	93.83	0.00e+00	1056.00
IUUC-Sce-106314	Saccharomyces cerevisiae	29.78	1.00e-60	228.00
IUUC-Sha-107653	Sarcophilus harrisii	94.37	0.00e+00	1060.00
IUUC-Sja-107840	Schizosaccharomyces japonicus	33.52	6.00e-79	288.00
IUUC-Spo-108115	Schizosaccharomyces pombe	32.08	6.00e-60	225.00
IUUC-Sar-113600	Sorex araneus	87.84	0.00e+00	963.00
IUUC-Sre-114901	Sporisorium reilianum	48.13	5.00e-67	250.00
IUUC-Ssc-115787	Sus scrofa	92.56	0.00e+00	1029.00
IUUC-Tgu-117510	Taeniopygia guttata	94.01	0.00e+00	1056.00
IUUC-Tru-117819	Takifugu rubripes	97.63	0.00e+00	1112.00
IUUC-Tsy-118828	Tarsius syrichta	94.37	0.00e+00	1057.00
IUUC-Tni-120468	Tetraodon nigroviridis	97.97	0.00e+00	1098.00
IUUC-Tme-127021	Tuber melanosporum	35.70	1.00e-85	310.00
IUUC-Tbe-127925	Tupaia belangeri	95.56	0.00e+00	1053.00
IUUC-Ttr-128899	Tursiops truncatus	94.01	0.00e+00	1054.00
IUUC-Uma-129449	Ustilago maydis	46.89	3.00e-66	247.00
IUUC-Vda-129802	Verticillium dahliae	37.01	2.00e-88	320.00
IUUC-Vpa-130082	Vicugna pacos	93.51	0.00e+00	880.00
IUUC-Xtr-132213	Xenopus tropicalis	95.38	0.00e+00	1059.00
IUUC-Xma-133646	Xiphophorus maculatus	99.82	0.00e+00	1096.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence