iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
ULD/UBL/ATG12	55.14	9.00e-31	129.00	IUUC-Hsa-046903

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Drosophila melanogaster

Functional Description
(View)

Required for autophagy.

Protein Sequence
(Fasta)

MAETPESQAA LSTSSSTPAD KDGSKICILL NATGNVPIIK KRTWTVDPNK TVGWIQTFIH 60
KFLKLDASEQ IFLYVNQTFA PAPDQIIKNL YECHGTNGKL VLYYCKNQAW G 111

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTTAATTCA TTAATTAGGA ACTATTTAAT TTAGTTACAT TCCAAATAAA TGGCAGAGAC 60
ACCAGAATCC CAGGCAGCGC TGAGCACTTC CTCCTCCACA CCTGCAGATA AGGATGGTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0072--Autophagy
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-1017--Isopeptide bond
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR007242--Atg12
IPR029071--Ubiquitin-rel_dom

Pfam

PF04110--APG12

Gene Ontology

GO:0034274--C:Atg12-Atg5-Atg16 complex
GO:0034045--C:pre-autophagosomal structure membrane
GO:0019776--F:Atg8 ligase activity
GO:0031386--F:protein tag
GO:0048102--P:autophagic cell death
GO:0000045--P:autophagosome assembly
GO:0006914--P:autophagy
GO:0006501--P:C-terminal protein lipidation
GO:0009267--P:cellular response to starvation
GO:0061723--P:glycophagy
GO:0035096--P:larval midgut cell programmed cell death
GO:0016236--P:macroautophagy
GO:0000422--P:mitophagy
GO:0044804--P:nucleophagy
GO:0035071--P:salivary gland cell autophagic cell death

KEGG

dme:Dmel_CG10861

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001177	Aegilops tauschii	32.18	2.00e-12	62.80
IUUC-Aml-002116	Ailuropoda melanoleuca	54.64	3.00e-29	120.00
IUUC-Atr-002615	Amborella trichopoda	33.00	1.00e-13	66.20
IUUC-Apl-003753	Anas platyrhynchos	70.00	1.00e-14	69.70
IUUC-Aca-005231	Anolis carolinensis	55.67	4.00e-25	105.00
IUUC-Aly-006172	Arabidopsis lyrata	32.67	2.00e-13	65.90
IUUC-Ath-006953	Arabidopsis thaliana	36.78	4.00e-13	64.70
IUUC-Ago-007970	Ashbya gossypii	28.74	8.00e-05	39.30
IUUC-Acl-008072	Aspergillus clavatus	25.56	2.00e-09	53.10
IUUC-Afl-008725	Aspergillus flavus	24.44	4.00e-09	53.50
IUUC-Afu-008967	Aspergillus fumigatus	26.67	9.00e-10	55.50
IUUC-Ani-009248	Aspergillus nidulans	24.17	4.00e-09	53.50
IUUC-Ang-009684	Aspergillus niger	26.67	7.00e-10	55.80
IUUC-Aor-009947	Aspergillus oryzae	24.44	4.00e-09	53.50
IUUC-Ame-011656	Astyanax mexicanus	52.75	3.00e-28	115.00
IUUC-Bgr-012174	Blumeria graminis	28.09	3.00e-11	60.10
IUUC-Bta-012483	Bos taurus	54.08	6.00e-29	118.00
IUUC-Bci-013755	Botrytis cinerea	27.37	2.00e-09	53.50
IUUC-Bdi-014156	Brachypodium distachyon	27.84	9.00e-12	60.50
IUUC-Bol-015683	Brassica oleracea	34.48	3.00e-13	65.50
IUUC-Bra-016802	Brassica rapa	35.63	1.00e-12	63.50
IUUC-Cel-018242	Caenorhabditis elegans	29.03	4.00e-10	55.50
IUUC-Cja-019514	Callithrix jacchus	55.34	2.00e-30	124.00
IUUC-Cfa-020748	Canis familiaris	54.64	2.00e-29	120.00
IUUC-Cpo-021965	Cavia porcellus	54.64	4.00e-29	119.00
IUUC-Cre-023009	Chlamydomonas reinhardtii	29.03	5.00e-10	54.70
IUUC-Csa-023494	Chlorocebus sabaeus	55.10	1.00e-29	120.00
IUUC-Cho-024631	Choloepus hoffmanni	54.64	8.00e-29	119.00
IUUC-Cin-025609	Ciona intestinalis	52.17	1.00e-26	110.00
IUUC-Cgl-026722	Colletotrichum gloeosporioides	34.09	3.00e-12	63.50
IUUC-Dre-027479	Danio rerio	45.95	4.00e-29	118.00
IUUC-Dno-029693	Dasypus novemcinctus	48.28	2.00e-19	87.00
IUUC-Dse-031440	Dothistroma septosporum	29.47	3.00e-11	60.10
IUUC-Ete-032550	Echinops telfairi	59.52	5.00e-28	115.00
IUUC-Eca-033553	Equus caballus	46.48	5.00e-30	122.00
IUUC-Fca-036524	Felis catus	45.00	2.00e-28	117.00
IUUC-Fal-036942	Ficedula albicollis	57.14	6.00e-28	114.00
IUUC-Fox-037753	Fusarium oxysporum	27.43	1.00e-11	61.20
IUUC-Gmo-039498	Gadus morhua	54.02	2.00e-27	113.00
IUUC-Ggr-039852	Gaeumannomyces graminis	28.57	3.00e-10	57.40
IUUC-Gga-041263	Gallus gallus	50.42	1.00e-30	124.00
IUUC-Gac-042346	Gasterosteus aculeatus	54.76	1.00e-27	113.00
IUUC-Gma-042896	Glycine max	33.33	1.00e-12	63.20
IUUC-Ggo-045601	Gorilla gorilla	55.67	3.00e-29	120.00
IUUC-Hsa-046903	Homo sapiens	55.10	1.00e-29	120.00
IUUC-Hvu-047239	Hordeum vulgare	32.18	8.00e-13	63.90
IUUC-Itr-048445	Ictidomys tridecemlineatus	54.64	6.00e-29	119.00
IUUC-Kpa-049355	Komagataella pastoris	29.17	2.00e-08	50.80
IUUC-Lch-050619	Latimeria chalumnae	58.62	5.00e-30	122.00
IUUC-Loc-052102	Lepisosteus oculatus	45.76	4.00e-13	64.70
IUUC-Lma-053299	Leptosphaeria maculans	31.34	2.00e-06	43.90
IUUC-Laf-054205	Loxodonta africana	55.05	3.00e-31	126.00
IUUC-Meu-056804	Macropus eugenii	51.82	2.00e-30	123.00
IUUC-Mor-057052	Magnaporthe oryzae	31.48	6.00e-13	66.20
IUUC-Mtr-057961	Medicago truncatula	34.48	3.00e-13	65.10
IUUC-Mla-059045	Melampsora laricipopulina	36.26	2.00e-17	80.10
IUUC-Mvi-060360	Microbotryum violaceum	37.36	9.00e-18	81.30
IUUC-Mmr-061654	Microcebus murinus	54.55	1.00e-29	120.00
IUUC-Mdo-062649	Monodelphis domestica	53.27	1.00e-30	124.00
IUUC-Mmu-064105	Mus musculus	53.47	2.00e-29	120.00
IUUC-Mac-065532	Musa acuminata	33.33	1.00e-13	66.60
IUUC-Mpu-066269	Mustela putorius furo	54.21	5.00e-32	129.00
IUUC-Mlu-067631	Myotis lucifugus	55.14	1.00e-31	127.00
IUUC-Nfi-068468	Neosartorya fischeri	26.67	6.00e-10	54.70
IUUC-Ncr-068750	Neurospora crassa	27.47	8.00e-10	55.50
IUUC-Nle-069483	Nomascus leucogenys	55.67	2.00e-29	121.00
IUUC-Opr-070936	Ochotona princeps	54.08	2.00e-28	117.00
IUUC-Obr-076322	Oryza brachyantha	33.33	5.00e-13	64.30
IUUC-Ogl-077226	Oryza glaberrima	35.37	7.00e-12	60.80
IUUC-Oin-079220	Oryza indica	37.10	7.00e-09	51.20
IUUC-Olo-080688	Oryza longistaminata	35.37	7.00e-12	60.80
IUUC-Ome-081265	Oryza meridionalis	35.37	7.00e-12	60.80
IUUC-Oru-084342	Oryza rufipogon	34.48	2.00e-12	65.10
IUUC-Osa-086212	Oryza sativa	35.37	7.00e-12	60.80
IUUC-Ola-087277	Oryzias latipes	58.89	2.00e-30	123.00
IUUC-Olu-087780	Ostreococcus lucimarinus	28.28	2.00e-08	49.30
IUUC-Oga-088175	Otolemur garnettii	55.10	1.00e-29	121.00
IUUC-Oar-089477	Ovis aries	54.64	1.00e-28	118.00
IUUC-Ptr-091129	Pan troglodytes	55.67	3.00e-29	120.00
IUUC-Psi-093351	Pelodiscus sinensis	53.06	4.00e-29	119.00
IUUC-Pno-094948	Phaeosphaeria nodorum	27.91	4.00e-06	42.70
IUUC-Ppa-095788	Physcomitrella patens	33.66	3.00e-15	72.40
IUUC-Pfo-096993	Poecilia formosa	46.90	6.00e-29	118.00
IUUC-Pab-098502	Pongo abelii	55.67	3.00e-29	120.00
IUUC-Pop-098819	Populus trichocarpa	31.18	1.00e-11	59.70
IUUC-Pca-100144	Procavia capensis	41.75	2.00e-18	84.00
IUUC-Ppe-101560	Prunus persica	34.12	2.00e-11	59.30
IUUC-Pva-102810	Pteropus vampyrus	51.14	2.00e-21	94.00
IUUC-Pgr-103531	Puccinia graminis	35.16	3.00e-18	82.40
IUUC-Ptt-103753	Puccinia triticina	36.26	7.00e-19	84.70
IUUC-Pyt-104733	Pyrenophora triticirepentis	29.07	3.00e-09	53.10
IUUC-Rno-106072	Rattus norvegicus	53.27	8.00e-31	125.00
IUUC-Sce-106275	Saccharomyces cerevisiae	28.44	1.00e-09	55.50
IUUC-Sha-107554	Sarcophilus harrisii	52.34	6.00e-31	125.00
IUUC-Sja-107682	Schizosaccharomyces japonicus	29.73	1.00e-12	64.30
IUUC-Spo-108275	Schizosaccharomyces pombe	29.41	9.00e-15	71.60
IUUC-Smo-109151	Selaginella moellendorffii	27.50	3.00e-09	52.00
IUUC-Sit-110270	Setaria italica	31.03	5.00e-12	61.20
IUUC-Sly-111862	Solanum lycopersicum	32.98	5.00e-13	64.30
IUUC-Stu-112663	Solanum tuberosum	40.82	3.00e-08	49.30
IUUC-Sbi-114148	Sorghum bicolor	31.03	5.00e-12	61.20
IUUC-Sre-115216	Sporisorium reilianum	35.16	3.00e-17	79.70
IUUC-Ssc-116051	Sus scrofa	55.10	1.00e-29	120.00
IUUC-Tgu-117008	Taeniopygia guttata	46.81	2.00e-08	49.70
IUUC-Tru-118466	Takifugu rubripes	55.95	4.00e-28	114.00
IUUC-Tsy-119334	Tarsius syrichta	49.53	6.00e-26	109.00
IUUC-Tni-119792	Tetraodon nigroviridis	57.14	8.00e-29	116.00
IUUC-Tca-121861	Theobroma cacao	32.38	5.00e-13	65.10
IUUC-Tvi-122499	Trichoderma virens	24.78	5.00e-10	55.50
IUUC-Tae-123431	Triticum aestivum	32.18	2.00e-12	62.80
IUUC-Tme-126934	Tuber melanosporum	32.95	7.00e-11	58.90
IUUC-Ttr-129001	Tursiops truncatus	54.64	5.00e-25	106.00
IUUC-Uma-129324	Ustilago maydis	37.36	5.00e-18	82.00
IUUC-Vda-129846	Verticillium dahliae	26.13	2.00e-09	54.30
IUUC-Vpa-130202	Vicugna pacos	70.00	6.00e-15	72.80
IUUC-Vvi-131474	Vitis vinifera	29.49	2.00e-07	47.40
IUUC-Xtr-132782	Xenopus tropicalis	54.46	1.00e-31	127.00
IUUC-Xma-134140	Xiphophorus maculatus	47.79	7.00e-30	121.00
IUUC-Yli-134517	Yarrowia lipolytica	33.75	1.00e-09	55.80
IUUC-Zma-134764	Zea mays	31.03	4.00e-12	61.60

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence