iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pab-098696

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01173428

Gene Name

AURKA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000011148.2	ENSPPYT00000012944.2	ENSPPYP00000012456.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	97.52	0.00e+00	802.00	IUUC-Hsa-046968

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Pongo abelii

Protein Sequence
(Fasta)

MDRSKENCIS GPVKVTAPVG GPKRVLVTQQ FPCQNPLPAN SGQAQRVLCP SNSSQRVPLQ 60
AQKLVSSHKP VQNQKQQKQL QATSVPHPVS RPLNNTQKSK QPLPSAPENN PEEELASKQK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCGAGCGCA GGCCAATCGG TTTTCTGGCT AGAGGGTTTA ACTCCTATTT AAAAAGAAGA 60
ACCTTTGAAT TCTAACGGCT GAGCTCTTAG AAGACTTGGG TCCTTGGGTC GCAGGTGGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR030616--Aur
IPR030611--AURKA
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0043203--C:axon hillock
GO:0005829--C:cytosol
GO:0042585--C:germinal vesicle
GO:0072687--C:meiotic spindle
GO:0072686--C:mitotic spindle
GO:0048471--C:perinuclear region of cytoplasm
GO:0045120--C:pronucleus
GO:0005876--C:spindle microtubule
GO:0031616--C:spindle pole centrosome
GO:0005524--F:ATP binding
GO:0035174--F:histone serine kinase activity
GO:0009948--P:anterior/posterior axis specification
GO:0051642--P:centrosome localization
GO:0097421--P:liver regeneration
GO:0007100--P:mitotic centrosome separation
GO:0007052--P:mitotic spindle organization
GO:0043066--P:negative regulation of apoptotic process
GO:0032091--P:negative regulation of protein binding
GO:1990138--P:neuron projection extension
GO:1900195--P:positive regulation of oocyte maturation
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0071539--P:protein localization to centrosome
GO:0031647--P:regulation of protein stability
GO:0009611--P:response to wounding
GO:0007057--P:spindle assembly involved in female meiosis I

KEGG

pon:100459866

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000930	Aegilops tauschii	63.44	2.00e-102	365.00
IUUC-Aml-001426	Ailuropoda melanoleuca	91.24	0.00e+00	714.00
IUUC-Atr-002453	Amborella trichopoda	63.67	1.00e-106	379.00
IUUC-Apl-003626	Anas platyrhynchos	70.56	8.00e-153	533.00
IUUC-Aca-004602	Anolis carolinensis	66.32	9.00e-147	513.00
IUUC-Aly-005878	Arabidopsis lyrata	64.31	9.00e-104	369.00
IUUC-Ath-007117	Arabidopsis thaliana	65.06	2.00e-104	371.00
IUUC-Acl-008199	Aspergillus clavatus	50.46	1.00e-86	312.00
IUUC-Afl-008419	Aspergillus flavus	55.84	2.00e-85	309.00
IUUC-Afu-008751	Aspergillus fumigatus	50.15	3.00e-86	311.00
IUUC-Ani-009181	Aspergillus nidulans	56.93	4.00e-89	321.00
IUUC-Ang-009787	Aspergillus niger	51.76	9.00e-87	313.00
IUUC-Aor-009980	Aspergillus oryzae	55.84	2.00e-85	309.00
IUUC-Ate-010286	Aspergillus terreus	49.70	1.00e-85	310.00
IUUC-Ame-010849	Astyanax mexicanus	73.17	5.00e-128	451.00
IUUC-Bgr-012110	Blumeria graminis	58.45	1.00e-87	316.00
IUUC-Bta-013474	Bos taurus	87.87	0.00e+00	712.00
IUUC-Bci-013756	Botrytis cinerea	52.98	8.00e-94	337.00
IUUC-Bdi-014257	Brachypodium distachyon	63.25	9.00e-104	369.00
IUUC-Bol-016310	Brassica oleracea	60.90	1.00e-101	362.00
IUUC-Bra-017438	Brassica rapa	60.90	6.00e-103	366.00
IUUC-Cel-018157	Caenorhabditis elegans	57.43	3.00e-101	361.00
IUUC-Cja-019282	Callithrix jacchus	95.30	0.00e+00	756.00
IUUC-Cfa-020162	Canis familiaris	89.43	0.00e+00	705.00
IUUC-Cpo-021764	Cavia porcellus	83.09	0.00e+00	658.00
IUUC-Cre-022827	Chlamydomonas reinhardtii	66.54	5.00e-106	377.00
IUUC-Csa-023694	Chlorocebus sabaeus	96.04	0.00e+00	725.00
IUUC-Cho-024350	Choloepus hoffmanni	95.92	7.00e-112	395.00
IUUC-Cin-025542	Ciona intestinalis	72.35	4.00e-116	410.00
IUUC-Csv-025873	Ciona savignyi	69.60	3.00e-116	410.00
IUUC-Cgl-026632	Colletotrichum gloeosporioides	50.16	8.00e-83	300.00
IUUC-Cne-026928	Cryptococcus neoformans	60.70	3.00e-93	335.00
IUUC-Cme-027336	Cyanidioschyzon merolae	65.45	4.00e-118	417.00
IUUC-Dre-028198	Danio rerio	61.83	1.00e-129	456.00
IUUC-Dno-029928	Dasypus novemcinctus	86.34	0.00e+00	646.00
IUUC-Dor-030238	Dipodomys ordii	78.82	0.00e+00	632.00
IUUC-Dse-031266	Dothistroma septosporum	59.55	2.00e-91	329.00
IUUC-Dme-032007	Drosophila melanogaster	61.45	2.00e-99	355.00
IUUC-Ete-032911	Echinops telfairi	67.02	1.00e-130	459.00
IUUC-Eca-033749	Equus caballus	91.49	0.00e+00	710.00
IUUC-Eeu-035170	Erinaceus europaeus	86.70	0.00e+00	699.00
IUUC-Fca-035498	Felis catus	90.05	0.00e+00	705.00
IUUC-Fal-037397	Ficedula albicollis	65.19	8.00e-146	509.00
IUUC-Fox-037747	Fusarium oxysporum	53.00	1.00e-90	326.00
IUUC-Fso-038429	Fusarium solani	52.35	9.00e-90	323.00
IUUC-Gmo-039378	Gadus morhua	74.72	2.00e-123	435.00
IUUC-Ggr-039939	Gaeumannomyces graminis	57.59	4.00e-95	341.00
IUUC-Gga-040187	Gallus gallus	70.90	4.00e-150	524.00
IUUC-Gac-042223	Gasterosteus aculeatus	59.49	9.00e-130	456.00
IUUC-Gma-042870	Glycine max	62.59	4.00e-98	350.00
IUUC-Ggo-045617	Gorilla gorilla	97.28	0.00e+00	800.00
IUUC-Hsa-046968	Homo sapiens	97.52	0.00e+00	802.00
IUUC-Hvu-047072	Hordeum vulgare	52.73	1.00e-80	292.00
IUUC-Itr-048233	Ictidomys tridecemlineatus	78.47	4.00e-176	610.00
IUUC-Kpa-049093	Komagataella pastoris	55.56	2.00e-75	275.00
IUUC-Lch-050346	Latimeria chalumnae	66.33	2.00e-143	501.00
IUUC-Lpe-051466	Leersia perrieri	63.73	2.00e-104	371.00
IUUC-Lma-053006	Leptosphaeria maculans	55.71	3.00e-88	318.00
IUUC-Laf-053422	Loxodonta africana	85.43	0.00e+00	688.00
IUUC-Mcc-055245	Macaca mulatta	96.22	0.00e+00	717.00
IUUC-Mor-056952	Magnaporthe oryzae	56.88	2.00e-90	325.00
IUUC-Mpo-057605	Magnaporthe poae	56.85	7.00e-96	343.00
IUUC-Mtr-057726	Medicago truncatula	63.64	8.00e-104	369.00
IUUC-Mla-059174	Melampsora laricipopulina	62.55	4.00e-97	348.00
IUUC-Mga-059562	Meleagris gallopavo	61.14	2.00e-116	412.00
IUUC-Mvi-060305	Microbotryum violaceum	61.22	1.00e-92	333.00
IUUC-Mmr-061588	Microcebus murinus	90.07	0.00e+00	735.00
IUUC-Mdo-061914	Monodelphis domestica	78.66	7.00e-174	603.00
IUUC-Mmu-063288	Mus musculus	81.98	0.00e+00	648.00
IUUC-Mac-064969	Musa acuminata	63.32	4.00e-105	374.00
IUUC-Mpu-066855	Mustela putorius furo	89.43	0.00e+00	699.00
IUUC-Mlu-068046	Myotis lucifugus	89.18	0.00e+00	696.00
IUUC-Nfi-068527	Neosartorya fischeri	51.40	2.00e-86	312.00
IUUC-Ncr-068678	Neurospora crassa	57.80	7.00e-93	333.00
IUUC-Nle-069848	Nomascus leucogenys	97.03	0.00e+00	798.00
IUUC-Opr-070589	Ochotona princeps	78.47	0.00e+00	626.00
IUUC-Ont-071733	Oreochromis niloticus	60.26	5.00e-121	427.00
IUUC-Oan-073399	Ornithorhynchus anatinus	86.44	9.00e-153	532.00
IUUC-Ocu-074063	Oryctolagus cuniculus	86.42	0.00e+00	707.00
IUUC-Oba-075264	Oryza barthii	63.99	2.00e-104	371.00
IUUC-Obr-076048	Oryza brachyantha	63.29	1.00e-103	369.00
IUUC-Ogl-077637	Oryza glaberrima	66.04	6.00e-103	367.00
IUUC-Ogu-078830	Oryza glumaepatula	63.32	2.00e-104	372.00
IUUC-Oin-079150	Oryza indica	63.99	9.00e-105	372.00
IUUC-Olo-080398	Oryza longistaminata	57.68	2.00e-82	298.00
IUUC-Ome-081544	Oryza meridionalis	54.04	3.00e-89	321.00
IUUC-Oni-082250	Oryza nivara	63.99	9.00e-105	372.00
IUUC-Opu-083638	Oryza punctata	63.67	3.00e-105	374.00
IUUC-Oru-084981	Oryza rufipogon	63.99	6.00e-105	373.00
IUUC-Osa-085961	Oryza sativa	63.99	6.00e-105	373.00
IUUC-Olu-087880	Ostreococcus lucimarinus	69.58	5.00e-111	394.00
IUUC-Oga-088891	Otolemur garnettii	89.12	0.00e+00	702.00
IUUC-Oar-090021	Ovis aries	86.39	0.00e+00	692.00
IUUC-Ptr-091458	Pan troglodytes	97.77	0.00e+00	803.00
IUUC-Pan-092546	Papio anubis	96.04	0.00e+00	727.00
IUUC-Psi-093280	Pelodiscus sinensis	74.54	6.00e-159	553.00
IUUC-Pma-094298	Petromyzon marinus	76.23	1.00e-119	422.00
IUUC-Pno-094847	Phaeosphaeria nodorum	59.02	5.00e-88	317.00
IUUC-Ppa-095855	Physcomitrella patens	65.57	6.00e-107	380.00
IUUC-Pfo-096428	Poecilia formosa	60.20	1.00e-125	443.00
IUUC-Pop-099405	Populus trichocarpa	61.89	6.00e-105	373.00
IUUC-Pca-100740	Procavia capensis	80.49	0.00e+00	651.00
IUUC-Ppe-101854	Prunus persica	62.85	1.00e-105	375.00
IUUC-Pva-103212	Pteropus vampyrus	87.89	0.00e+00	680.00
IUUC-Pgr-103474	Puccinia graminis	62.50	4.00e-97	348.00
IUUC-Ptt-103933	Puccinia triticina	48.65	2.00e-60	226.00
IUUC-Pte-104089	Pyrenophora teres	55.83	2.00e-88	319.00
IUUC-Pyt-104555	Pyrenophora triticirepentis	55.83	1.00e-88	319.00
IUUC-Rno-105057	Rattus norvegicus	83.21	0.00e+00	660.00
IUUC-Sha-107137	Sarcophilus harrisii	80.15	1.00e-176	612.00
IUUC-Sja-107767	Schizosaccharomyces japonicus	57.00	1.00e-97	349.00
IUUC-Spo-108078	Schizosaccharomyces pombe	60.73	4.00e-100	357.00
IUUC-Smo-109288	Selaginella moellendorffii	63.32	9.00e-107	379.00
IUUC-Sit-110246	Setaria italica	62.98	6.00e-105	373.00
IUUC-Sly-111379	Solanum lycopersicum	64.73	5.00e-106	377.00
IUUC-Stu-112777	Solanum tuberosum	61.54	3.00e-105	374.00
IUUC-Sbi-114325	Sorghum bicolor	64.16	3.00e-104	370.00
IUUC-Sre-115203	Sporisorium reilianum	58.27	1.00e-79	290.00
IUUC-Ssc-115361	Sus scrofa	88.12	0.00e+00	706.00
IUUC-Tgu-116967	Taeniopygia guttata	71.93	5.00e-145	507.00
IUUC-Tru-117570	Takifugu rubripes	61.92	1.00e-135	475.00
IUUC-Tsy-119280	Tarsius syrichta	70.05	3.00e-147	514.00
IUUC-Tni-120721	Tetraodon nigroviridis	62.28	1.00e-133	469.00
IUUC-Tca-121494	Theobroma cacao	61.97	2.00e-104	371.00
IUUC-Tre-121869	Trichoderma reesei	55.08	5.00e-95	340.00
IUUC-Tvi-122510	Trichoderma virens	56.57	6.00e-93	334.00
IUUC-Tae-123071	Triticum aestivum	63.44	2.00e-102	365.00
IUUC-Tur-126240	Triticum urartu	63.44	5.00e-102	363.00
IUUC-Tme-126921	Tuber melanosporum	62.55	1.00e-94	340.00
IUUC-Tbe-127872	Tupaia belangeri	83.46	0.00e+00	630.00
IUUC-Ttr-129134	Tursiops truncatus	88.66	0.00e+00	670.00
IUUC-Uma-129412	Ustilago maydis	58.87	3.00e-78	285.00
IUUC-Vda-130003	Verticillium dahliae	53.00	3.00e-93	335.00
IUUC-Vvi-131272	Vitis vinifera	63.29	3.00e-105	374.00
IUUC-Xtr-132019	Xenopus tropicalis	64.93	1.00e-146	512.00
IUUC-Xma-134203	Xiphophorus maculatus	60.20	2.00e-131	462.00
IUUC-Yli-134503	Yarrowia lipolytica	53.46	6.00e-85	307.00
IUUC-Zma-135232	Zea mays	61.49	6.00e-105	373.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence