iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Spo-108026

UUCD1 version

UUC-ScP-00146

Ensembl Protein ID

SPAC13G6.01c.1:pep

UniProt Accession

P36607; RAD5_SCHPO

Genbank Protein ID

CAA52686.1; CAA89964.1

Protein Name

DNA repair protein rad8; DNA repair protein RAD5 homolog

Genbank Nucleotide ID

X74615; CU329670

Gene Name

rad8; SPAC13G6.01c; SPAC5H10.14c

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SPAC13G6.01c	SPAC13G6.01c.1	SPAC13G6.01c.1:pep

Annotation

mRNA Expression
GEO
Protein-protein Interaction
Mentha
Post-translational Modifications (PTMs)
dbPAF	dbPTM	UniProt
Protein Expression/Proteomics

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 activity/RING/RING	RING	24875629

Classification

Family	E-value	Score	Start	End
E3 activity/RING/RING	0.0039	15.8	877	923

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iC++++ + pl+l+C+H+ + dCl ++++++k+      +C +Cr
   Q: 877  CPICCNEPIQNPLLLNCKHACCGDCLsEHIQYQKRRNIIPPLCHTCR 923
           ******99777***************888877777777777899997 PP

Organism

Schizosaccharomyces pombe

Functional Description
(View)

Probable helicase, member of the UBC2/RAD6 epistasis group. Functions with DNA repair protein rad18 in error-free postreplication DNA repair. Involved in the maintenance of wild-type rates of instability of simple repetitive sequences such as poly(GT) repeats (By similarity). Plays a role in surviving topoisomerase-mediated DNA damage (PubMed:14871939).

Protein Sequence
(Fasta)

MKRKVQKIID EAPLEENSPP RFFDSDVEAD SKPNDLTAAN SIVDLKTNSQ HENANAAGKE 60
YGDSGVSESW VLDFLSVTGE KTISEFLAQK IWKTSNGDLN VAVDMYFDES FNIKNSNPDS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTTCCTCCA AGATTTAGCC AGCGAGCTAT TTCTATAATT ATTAGATTTT CCTCCCCAAA 60
TATTCAACTT TTTTAGAGTC TCCTTTCATC ATTTATAATC CTATTAGAAT ATTTAAATTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0227--DNA damage
KW-0234--DNA repair
KW-0238--DNA-binding
KW-0347--Helicase
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR014905--HIRAN
IPR027417--P-loop_NTPase
IPR000330--SNF2_N
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS50089--ZF_RING_2

Pfam

PF00271--Helicase_C
PF08797--HIRAN
PF00176--SNF2_N

SMART

SM00487--DEXDc
SM00490--HELICc
SM00910--HIRAN

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0035861--C:site of double-strand break
GO:0005524--F:ATP binding
GO:0003677--F:DNA binding
GO:0004386--F:helicase activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0006289--P:nucleotide-excision repair
GO:0006301--P:postreplication repair

KEGG

spo:SPAC13G6.01c

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000167	Aegilops tauschii	32.60	1.00e-126	445.00
IUUC-Atr-003058	Amborella trichopoda	31.72	2.00e-123	435.00
IUUC-Aly-005600	Arabidopsis lyrata	33.04	3.00e-135	474.00
IUUC-Ath-007517	Arabidopsis thaliana	32.54	1.00e-134	472.00
IUUC-Ago-007997	Ashbya gossypii	34.25	4.00e-144	503.00
IUUC-Acl-008022	Aspergillus clavatus	35.55	0.00e+00	665.00
IUUC-Afl-008514	Aspergillus flavus	35.92	0.00e+00	667.00
IUUC-Afu-009055	Aspergillus fumigatus	36.17	0.00e+00	667.00
IUUC-Ani-009340	Aspergillus nidulans	36.31	0.00e+00	675.00
IUUC-Ang-009785	Aspergillus niger	36.71	0.00e+00	659.00
IUUC-Aor-010158	Aspergillus oryzae	35.92	0.00e+00	666.00
IUUC-Ate-010536	Aspergillus terreus	34.75	3.00e-167	580.00
IUUC-Bgr-012147	Blumeria graminis	36.74	0.00e+00	632.00
IUUC-Bci-013741	Botrytis cinerea	39.61	0.00e+00	677.00
IUUC-Bdi-014646	Brachypodium distachyon	33.08	4.00e-133	467.00
IUUC-Bol-015995	Brassica oleracea	33.74	1.00e-135	476.00
IUUC-Bra-017004	Brassica rapa	33.75	3.00e-133	467.00
IUUC-Cja-019685	Callithrix jacchus	32.61	8.00e-82	296.00
IUUC-Cpo-021361	Cavia porcellus	32.06	6.00e-77	280.00
IUUC-Cre-022824	Chlamydomonas reinhardtii	24.79	7.00e-62	231.00
IUUC-Csa-023894	Chlorocebus sabaeus	32.67	3.00e-82	298.00
IUUC-Cgl-026606	Colletotrichum gloeosporioides	42.76	4.00e-175	606.00
IUUC-Cne-026886	Cryptococcus neoformans	34.73	2.00e-138	485.00
IUUC-Cme-027110	Cyanidioschyzon merolae	29.31	4.00e-90	324.00
IUUC-Dre-027867	Danio rerio	32.05	3.00e-83	301.00
IUUC-Dor-030590	Dipodomys ordii	30.99	8.00e-38	150.00
IUUC-Dse-031471	Dothistroma septosporum	37.03	0.00e+00	663.00
IUUC-Fca-035390	Felis catus	32.06	4.00e-74	271.00
IUUC-Fox-038039	Fusarium oxysporum	41.53	3.00e-169	587.00
IUUC-Fso-038179	Fusarium solani	38.24	0.00e+00	649.00
IUUC-Gmo-038544	Gadus morhua	32.01	1.00e-83	302.00
IUUC-Ggr-039735	Gaeumannomyces graminis	37.15	0.00e+00	647.00
IUUC-Gac-042401	Gasterosteus aculeatus	32.75	1.00e-85	309.00
IUUC-Gma-044315	Glycine max	32.24	6.00e-130	456.00
IUUC-Ggo-045628	Gorilla gorilla	31.94	3.00e-83	301.00
IUUC-Hsa-045930	Homo sapiens	32.67	4.00e-83	300.00
IUUC-Hvu-047747	Hordeum vulgare	32.43	1.00e-128	452.00
IUUC-Itr-048493	Ictidomys tridecemlineatus	32.55	4.00e-80	291.00
IUUC-Kpa-049087	Komagataella pastoris	34.24	8.00e-146	509.00
IUUC-Lpe-051123	Leersia perrieri	34.07	1.00e-133	468.00
IUUC-Loc-052785	Lepisosteus oculatus	32.08	3.00e-85	308.00
IUUC-Lma-052956	Leptosphaeria maculans	38.16	0.00e+00	661.00
IUUC-Mcc-055493	Macaca mulatta	32.61	1.00e-82	299.00
IUUC-Mor-057210	Magnaporthe oryzae	38.13	0.00e+00	670.00
IUUC-Mpo-057407	Magnaporthe poae	37.51	0.00e+00	667.00
IUUC-Mtr-058565	Medicago truncatula	32.79	2.00e-131	461.00
IUUC-Mvi-060322	Microbotryum violaceum	31.93	3.00e-102	364.00
IUUC-Mmu-064338	Mus musculus	32.55	3.00e-79	288.00
IUUC-Mac-064548	Musa acuminata	31.01	3.00e-121	427.00
IUUC-Mlu-068076	Myotis lucifugus	31.94	2.00e-74	272.00
IUUC-Nfi-068354	Neosartorya fischeri	36.22	0.00e+00	671.00
IUUC-Ncr-068844	Neurospora crassa	38.31	0.00e+00	662.00
IUUC-Nle-069947	Nomascus leucogenys	32.85	4.00e-83	301.00
IUUC-Ont-071782	Oreochromis niloticus	32.57	9.00e-87	313.00
IUUC-Oba-075937	Oryza barthii	32.64	3.00e-120	424.00
IUUC-Obr-076403	Oryza brachyantha	32.02	8.00e-129	452.00
IUUC-Ogl-077573	Oryza glaberrima	34.17	9.00e-136	476.00
IUUC-Ogu-078083	Oryza glumaepatula	31.77	7.00e-128	449.00
IUUC-Oin-079146	Oryza indica	34.17	7.00e-136	476.00
IUUC-Olo-080615	Oryza longistaminata	32.88	1.00e-131	462.00
IUUC-Ome-081448	Oryza meridionalis	33.19	9.00e-124	436.00
IUUC-Oni-082773	Oryza nivara	31.77	3.00e-127	447.00
IUUC-Opu-083675	Oryza punctata	32.57	4.00e-132	464.00
IUUC-Oru-084543	Oryza rufipogon	31.77	2.00e-126	444.00
IUUC-Osa-085686	Oryza sativa	35.59	5.00e-126	443.00
IUUC-Ptr-091418	Pan troglodytes	32.49	7.00e-83	300.00
IUUC-Pan-092579	Papio anubis	35.11	2.00e-45	176.00
IUUC-Pno-094916	Phaeosphaeria nodorum	38.99	0.00e+00	662.00
IUUC-Ppa-095877	Physcomitrella patens	32.34	7.00e-129	453.00
IUUC-Pfo-096540	Poecilia formosa	31.72	1.00e-83	302.00
IUUC-Pab-098010	Pongo abelii	32.67	6.00e-83	300.00
IUUC-Pop-099320	Populus trichocarpa	32.27	5.00e-130	456.00
IUUC-Pca-100648	Procavia capensis	31.05	6.00e-79	287.00
IUUC-Ppe-101820	Prunus persica	31.66	4.00e-130	457.00
IUUC-Pva-102896	Pteropus vampyrus	32.40	2.00e-68	252.00
IUUC-Pgr-103454	Puccinia graminis	29.23	6.00e-90	324.00
IUUC-Ptt-103829	Puccinia triticina	30.75	3.00e-77	281.00
IUUC-Pte-104242	Pyrenophora teres	38.79	0.00e+00	658.00
IUUC-Pyt-104728	Pyrenophora triticirepentis	38.47	0.00e+00	671.00
IUUC-Rno-106130	Rattus norvegicus	33.33	1.00e-80	292.00
IUUC-Sce-106396	Saccharomyces cerevisiae	34.62	8.00e-144	503.00
IUUC-Sja-107985	Schizosaccharomyces japonicus	48.36	0.00e+00	954.00
IUUC-Ssl-108388	Sclerotinia sclerotiorum	39.92	0.00e+00	678.00
IUUC-Smo-109311	Selaginella moellendorffii	29.63	1.00e-84	305.00
IUUC-Sit-110076	Setaria italica	32.57	7.00e-133	466.00
IUUC-Sly-111908	Solanum lycopersicum	32.45	5.00e-135	473.00
IUUC-Stu-112600	Solanum tuberosum	32.81	4.00e-128	450.00
IUUC-Sar-113719	Sorex araneus	32.07	7.00e-83	300.00
IUUC-Sbi-113927	Sorghum bicolor	31.89	2.00e-129	454.00
IUUC-Sre-115131	Sporisorium reilianum	30.31	2.00e-133	468.00
IUUC-Tru-117768	Takifugu rubripes	32.69	1.00e-81	296.00
IUUC-Tca-121137	Theobroma cacao	32.14	3.00e-132	464.00
IUUC-Tre-121896	Trichoderma reesei	38.56	0.00e+00	650.00
IUUC-Tvi-122597	Trichoderma virens	37.78	0.00e+00	640.00
IUUC-Tae-125934	Triticum aestivum	31.69	3.00e-136	477.00
IUUC-Tur-125999	Triticum urartu	36.92	2.00e-123	434.00
IUUC-Tme-126953	Tuber melanosporum	37.69	0.00e+00	648.00
IUUC-Ttr-128243	Tursiops truncatus	31.49	7.00e-40	157.00
IUUC-Uma-129629	Ustilago maydis	30.99	7.00e-92	330.00
IUUC-Vda-129849	Verticillium dahliae	39.42	1.00e-155	542.00
IUUC-Vvi-131508	Vitis vinifera	32.77	5.00e-133	467.00
IUUC-Xtr-132730	Xenopus tropicalis	33.45	2.00e-87	315.00
IUUC-Yli-134588	Yarrowia lipolytica	34.92	1.00e-148	518.00
IUUC-Zma-135801	Zea mays	31.58	1.00e-115	409.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence