iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-106618

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01069000

Gene Name

UHRF1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000000293.1	ENSSHAT00000000336.1	ENSSHAP00000000331.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.10e-08	35.3	340	387
ULD/UDP/UBQ/UBQ_PIM	2.70e-14	53.0	15	91

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 4    ClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCrs 53
           C vCg +++ +k  ++C++C+ +fH  Cl+++  +  p++e+w+Cp+Cr+
   Q: 340  CYVCGGKQDPDK-QLMCDECDMAFHIYCLNPP-LSRIPDDEDWYCPECRN 387
           99****999997.566****************.***************85 PP

ULD/UDP/UBQ/UBQ_PIM

   S: 1    mkltvktlkgke.fel.evseddtveelKekiakesgvppeqqkLIyaGkiLkDdttLselgikdgsvvhlvvkksk 75
           m+++v+t++gke  ++ ++s+ ++veel+ ki++++ v+p +q+L y Gk+++D  +L ++++  +++v l+v++s+
   Q: 15   MWIQVRTMDGKEtHRVdSLSKLTKVEELRLKIQEVFTVEPGRQRLFYRGKQMEDGHSLFDYNVGLNDIVQLLVRQSP 91
           89**********7667789999****************************************************987 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

LFLFSFLPFR RATTMWIQVR TMDGKETHRV DSLSKLTKVE ELRLKIQEVF TVEPGRQRLF 60
YRGKQMEDGH SLFDYNVGLN DIVQLLVRQS PAVLSVPSKE KDSELSDTDS GCCSGQSESD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCTTCCTTT TTTCTTTCCT TCCTTTCCGC AGAGCTACCA CCATGTGGAT CCAGGTTCGC 60
ACCATGGATG GCAAGGAGAC CCACCGGGTA GACTCTCTCT CTAAGCTCAC CAAGGTGGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR015947--PUA-like_domain
IPR014722--Rib_L2_dom2
IPR003105--SRA_YDG
IPR021991--TTD_dom
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50053--UBIQUITIN_2
PS51015--YDG
PS50016--ZF_PHD_2
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00628--PHD
PF02182--SAD_SRA
PF12148--TTD
PF00240--ubiquitin

SMART

SM00249--PHD
SM00184--RING
SM00466--SRA
SM00213--UBQ

Gene Ontology

GO:0005720--C:nuclear heterochromatin
GO:0016363--C:nuclear matrix
GO:0005657--C:replication fork
GO:0044729--F:hemi-methylated DNA-binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0010390--P:histone monoubiquitination
GO:0010216--P:maintenance of DNA methylation
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0051865--P:protein autoubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000242	Aegilops tauschii	50.52	2.00e-42	167.00
IUUC-Aml-001285	Ailuropoda melanoleuca	81.70	0.00e+00	1021.00
IUUC-Atr-002603	Amborella trichopoda	36.43	2.00e-50	193.00
IUUC-Apl-003819	Anas platyrhynchos	84.63	0.00e+00	1261.00
IUUC-Aca-004970	Anolis carolinensis	66.59	0.00e+00	1055.00
IUUC-Ame-011845	Astyanax mexicanus	73.19	0.00e+00	1103.00
IUUC-Bta-012600	Bos taurus	74.22	0.00e+00	1148.00
IUUC-Bci-013703	Botrytis cinerea	31.03	2.00e-11	63.50
IUUC-Cja-018864	Callithrix jacchus	75.62	0.00e+00	1205.00
IUUC-Cfa-020558	Canis familiaris	77.56	0.00e+00	1200.00
IUUC-Cpo-022125	Cavia porcellus	74.34	0.00e+00	1169.00
IUUC-Cre-022645	Chlamydomonas reinhardtii	30.46	3.00e-22	100.00
IUUC-Csa-023649	Chlorocebus sabaeus	75.03	0.00e+00	1167.00
IUUC-Cin-025454	Ciona intestinalis	53.00	0.00e+00	764.00
IUUC-Cgl-026498	Colletotrichum gloeosporioides	32.64	9.00e-12	65.10
IUUC-Cne-026942	Cryptococcus neoformans	46.67	2.00e-29	120.00
IUUC-Dre-028200	Danio rerio	73.72	0.00e+00	1149.00
IUUC-Dno-029523	Dasypus novemcinctus	76.29	0.00e+00	920.00
IUUC-Dor-031084	Dipodomys ordii	74.32	0.00e+00	1166.00
IUUC-Eca-033266	Equus caballus	76.66	0.00e+00	1155.00
IUUC-Eeu-035077	Erinaceus europaeus	81.94	3.00e-143	501.00
IUUC-Fca-035685	Felis catus	69.81	0.00e+00	1065.00
IUUC-Fal-037550	Ficedula albicollis	80.32	0.00e+00	1151.00
IUUC-Gmo-039452	Gadus morhua	71.02	0.00e+00	1110.00
IUUC-Gga-040484	Gallus gallus	82.67	0.00e+00	1345.00
IUUC-Gac-042196	Gasterosteus aculeatus	69.34	0.00e+00	1113.00
IUUC-Ggo-045414	Gorilla gorilla	77.74	0.00e+00	1221.00
IUUC-Hsa-046236	Homo sapiens	77.74	0.00e+00	1221.00
IUUC-Itr-047867	Ictidomys tridecemlineatus	75.12	0.00e+00	1150.00
IUUC-Lch-050162	Latimeria chalumnae	71.29	0.00e+00	1117.00
IUUC-Lpe-050756	Leersia perrieri	45.12	6.00e-40	159.00
IUUC-Loc-051806	Lepisosteus oculatus	74.87	0.00e+00	1188.00
IUUC-Lma-052953	Leptosphaeria maculans	25.35	8.00e-11	62.00
IUUC-Laf-053671	Loxodonta africana	77.24	0.00e+00	1216.00
IUUC-Mcc-055513	Macaca mulatta	77.99	0.00e+00	1226.00
IUUC-Mpo-057318	Magnaporthe poae	30.39	2.00e-09	57.40
IUUC-Mla-058836	Melampsora laricipopulina	42.16	1.00e-33	137.00
IUUC-Mga-059759	Meleagris gallopavo	83.40	0.00e+00	1234.00
IUUC-Mvi-060378	Microbotryum violaceum	47.28	2.00e-33	136.00
IUUC-Mmr-060600	Microcebus murinus	68.86	0.00e+00	999.00
IUUC-Mdo-061911	Monodelphis domestica	95.98	0.00e+00	1470.00
IUUC-Mmu-063738	Mus musculus	67.99	0.00e+00	1050.00
IUUC-Mpu-065696	Mustela putorius furo	77.33	0.00e+00	1191.00
IUUC-Mlu-067538	Myotis lucifugus	70.87	0.00e+00	1107.00
IUUC-Opr-070813	Ochotona princeps	61.04	4.00e-154	537.00
IUUC-Ont-072292	Oreochromis niloticus	71.59	0.00e+00	1133.00
IUUC-Oba-075108	Oryza barthii	45.12	2.00e-40	160.00
IUUC-Obr-076572	Oryza brachyantha	46.01	4.00e-40	159.00
IUUC-Ogl-077177	Oryza glaberrima	45.12	1.00e-40	161.00
IUUC-Ogu-078298	Oryza glumaepatula	45.12	1.00e-40	160.00
IUUC-Oin-079911	Oryza indica	45.12	2.00e-40	160.00
IUUC-Olo-080527	Oryza longistaminata	44.74	5.00e-35	142.00
IUUC-Ome-081137	Oryza meridionalis	45.16	2.00e-34	141.00
IUUC-Opu-083974	Oryza punctata	45.54	2.00e-40	160.00
IUUC-Osa-085339	Oryza sativa	45.12	1.00e-40	160.00
IUUC-Ola-086416	Oryzias latipes	70.29	0.00e+00	1126.00
IUUC-Oga-088221	Otolemur garnettii	76.02	0.00e+00	1207.00
IUUC-Oar-089604	Ovis aries	70.11	0.00e+00	1051.00
IUUC-Ptr-090559	Pan troglodytes	77.83	0.00e+00	1219.00
IUUC-Pan-092855	Papio anubis	77.99	0.00e+00	1228.00
IUUC-Psi-093763	Pelodiscus sinensis	87.61	0.00e+00	993.00
IUUC-Pma-094339	Petromyzon marinus	65.69	0.00e+00	976.00
IUUC-Ppa-095940	Physcomitrella patens	35.03	7.00e-49	189.00
IUUC-Pfo-096243	Poecilia formosa	68.90	0.00e+00	1106.00
IUUC-Pab-098243	Pongo abelii	77.37	0.00e+00	1206.00
IUUC-Pca-100503	Procavia capensis	72.91	0.00e+00	1123.00
IUUC-Pva-102240	Pteropus vampyrus	77.07	0.00e+00	972.00
IUUC-Pgr-103644	Puccinia graminis	48.17	3.00e-33	136.00
IUUC-Ptt-103867	Puccinia triticina	45.00	1.00e-33	137.00
IUUC-Rno-105345	Rattus norvegicus	68.76	0.00e+00	1065.00
IUUC-Sar-113651	Sorex araneus	72.18	7.00e-88	317.00
IUUC-Sbi-114726	Sorghum bicolor	50.00	2.00e-41	164.00
IUUC-Sre-115182	Sporisorium reilianum	43.62	3.00e-34	139.00
IUUC-Ssc-116081	Sus scrofa	75.65	0.00e+00	1183.00
IUUC-Tgu-116538	Taeniopygia guttata	84.82	0.00e+00	1078.00
IUUC-Tru-117599	Takifugu rubripes	69.60	0.00e+00	1098.00
IUUC-Tca-121614	Theobroma cacao	46.49	2.00e-46	180.00
IUUC-Tme-127149	Tuber melanosporum	48.55	1.00e-27	117.00
IUUC-Ttr-128522	Tursiops truncatus	75.22	0.00e+00	1164.00
IUUC-Vda-129727	Verticillium dahliae	27.78	9.00e-08	50.80
IUUC-Xtr-132432	Xenopus tropicalis	73.49	0.00e+00	1164.00
IUUC-Xma-133516	Xiphophorus maculatus	69.69	0.00e+00	1119.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence