• HOME
  • BROWSE
  • SEARCH
  • LINK
  • DOWNLOAD
  • USER GUIDE
  • Protein
  • Gene
  • Annotation
  • Details
  • Classification
  • Domain Profile
  • Function
  • Protein Sequence
  • Nucleotide Sequence
  • Keyword
  • GO
  • Orthology
  • TOP

Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Hsa-046614
Ensembl Protein ID ENSP00000467024.1
UniProt Accession P54725; K7ESE3; Q59EU8; Q5M7Z1; RD23A_HUMAN
Genbank Protein ID BAA04767.1; AAN39383.1; BAD92950.1; AAB51177.1; AAH14026.1; AAH88364.1
Protein Name UV excision repair protein RAD23 homolog A
Genbank Nucleotide ID D21235; AF549209; BX448989; AC092069; BC014026; BC088364
Gene Name RAD23A; Hhr23A
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000179262.9 ENST00000591499.5 ENSP00000466243.1
ENSG00000179262.9 ENST00000316856.7 ENSP00000321365.3
ENSG00000179262.9 ENST00000586534.5 ENSP00000467024.1
ENSG00000179262.9 ENST00000592268.5 ENSP00000468674.1
ENSG00000179262.9 ENST00000586375.1 ENSP00000466226.1
ENSG00000179262.9 ENST00000590881.1 ENSP00000467628.1
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbAREsitecircBaseCircNet
miRTarBasemicroRNATRANSFACmiRWalk
TargetScanRepTarSomamiRmiRcode
RAID2
Protein-protein Interaction
IIDPINAHINTMentha
InWeb_IM
Protein 3D Structure
PDBMMDB
Disease-associated Information
GWASdbOMIM
Post-translational Modifications (PTMs)
CPLMdbPAFPhosSNPPhosphositePlus
dbPTMHPRDPhospho.ELMUniProt
PHOSIDABioGRIDmUbiSiDa
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Reviewed
Details
Family Domain References (PMIDs)
UBD/Alpha-Helix/UBA UBA 15321727; 15949443; 16405905; 17098253; 17242378
ULD/UDP/UBQ/UBQ_PIM UBQ_PIM 10708769; 10915768; 11827521; 12970176; 14557549
Classification
Family E-value Score Start End
UBD/Alpha-Helix/UBA 2.10e-20 73.8 162 201
ULD/UDP/UBQ/UBQ_PIM 1.10e-25 91.0 3 80
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/Alpha-Helix/UBA
   S: 2    ededkleqlveMGFdreealqaLraannnleaAveyLldg 41
           e+e +l ++++MG++re+++ aLra++nn+ +AveyLl+g
   Q: 162  EYETMLTEIMSMGYERERVVAALRASYNNPHRAVEYLLTG 201
           7899**********************************97 PP
   

   ULD/UDP/UBQ/UBQ_PIM
   S: 1    mkltvktlkgkefelevseddtveelKekiakesg...vppeqqkLIyaGkiLkDdttLselgikdgsvvhlvvkksk 75
           +++t+ktl++++f++++++d+tv+ lKeki++e+g   +p++ qkLIyaGkiL+Dd +++++ i+++++v+++v+k+k
   Q: 3    VTITLKTLQQQTFKIRMEPDETVKVLKEKIEAEKGrdaFPVAGQKLIYAGKILSDDVPIRDYRIDEKNFVVVMVTKTK 80
           68*************************************************************************987 PP
   
Organism Homo sapiens
Functional Description
(View)

Functional Description


     Interacts with XPC; the interaction is suggesting the existence of a functional equivalent variant XPC complex. Interacts with PSMD4 and PSMC5. Interacts with ATXN3. Interacts with HIV-1 vpr. Interacts with UBQLN2.
 Interacts with XPC; the interaction is suggesting the existence of a functional equivalent variant XPC complex. Interacts with PSMD4 and PSMC5. Interacts with ATXN3. Interacts with HIV-1 vpr. Interacts with UBQLN2.
Protein Sequence
(Fasta)
MAVTITLKTL QQQTFKIRME PDETVKVLKE KIEAEKGRDA FPVAGQKLIY AGKILSDDVP 60
IRDYRIDEKN FVVVMVTKTK AGQGTSAPPE ASPTAAPESS TSFPPAPTSG MSHPPPAARE 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046614|UBD,UBA;ULD,UBQ_PIM|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCGCGGCGCG GCGCGCCTGG GCGCTAAGAT GGCGGCGGCG TGAGTTGCAT GTTGTGTGAG 60
GATCCCGGGG CCGCCGCGTC GCTCGGGCCC CGCCATGGCC GTCACCATCA CGCTCAAAAC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046614|UBD,UBA;ULD,UBQ_PIM|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0002--3D-structure
KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0227--DNA damage
KW-0234--DNA repair
KW-0945--Host-virus interaction
KW-1017--Isopeptide bond
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-0647--Proteasome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0832--Ubl conjugation
Interpro

IPR004806--Rad23
IPR006636--STI1_HS-bd
IPR015940--UBA
IPR009060--UBA-like
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR015360--XPC-bd
PROSITE

PS50030--UBA
PS50053--UBIQUITIN_2
Pfam

PF00627--UBA
PF00240--ubiquitin
PF09280--XPC-binding
PRINTS

PR01839--RAD23PROTEIN
SMART

SM00727--STI1
SM00165--UBA
SM00213--UBQ
Gene Ontology

GO:0005829--C:cytosol
GO:0005815--C:microtubule organizing center
GO:0005654--C:nucleoplasm
GO:0000502--C:proteasome complex
GO:0003684--F:damaged DNA binding
GO:0031593--F:polyubiquitin binding
GO:0003697--F:single-stranded DNA binding
GO:1990381--F:ubiquitin-specific protease binding
GO:0006289--P:nucleotide-excision repair
GO:0045070--P:positive regulation of viral genome replication
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0016579--P:protein deubiquitination
GO:0032434--P:regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0016032--P:viral process
KEGG hsa:5886
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000770 Aegilops tauschii 38.11 2.00e-32 133.00
IUUC-Aml-001515 Ailuropoda melanoleuca 93.04 1.00e-144 506.00
IUUC-Atr-002756 Amborella trichopoda 35.31 1.00e-49 190.00
IUUC-Aca-004704 Anolis carolinensis 78.77 9.00e-113 400.00
IUUC-Ani-009460 Aspergillus nidulans 38.80 3.00e-29 122.00
IUUC-Bgr-012056 Blumeria graminis 33.66 2.00e-21 96.70
IUUC-Bta-012377 Bos taurus 96.14 1.00e-148 518.00
IUUC-Bci-013933 Botrytis cinerea 37.31 9.00e-21 94.40
IUUC-Bdi-014718 Brachypodium distachyon 30.60 1.00e-40 160.00
IUUC-Cel-018364 Caenorhabditis elegans 31.98 1.00e-28 120.00
IUUC-Cja-018946 Callithrix jacchus 98.62 2.00e-149 521.00
IUUC-Cfa-020577 Canis familiaris 97.25 4.00e-155 540.00
IUUC-Cpo-021850 Cavia porcellus 93.11 6.00e-167 580.00
IUUC-Csa-023183 Chlorocebus sabaeus 99.72 9.00e-157 546.00
IUUC-Cgl-026495 Colletotrichum gloeosporioides 33.00 1.00e-21 97.10
IUUC-Dno-030017 Dasypus novemcinctus 92.37 1.00e-129 456.00
IUUC-Dor-030358 Dipodomys ordii 84.62 2.00e-126 445.00
IUUC-Eca-033599 Equus caballus 93.51 2.00e-138 484.00
IUUC-Fca-036051 Felis catus 96.42 7.00e-153 533.00
IUUC-Gmo-038528 Gadus morhua 57.46 2.00e-85 308.00
IUUC-Gga-040133 Gallus gallus 86.98 6.00e-75 274.00
IUUC-Gma-044077 Glycine max 34.95 8.00e-46 177.00
IUUC-Ggo-045084 Gorilla gorilla 100.00 1.00e-156 546.00
IUUC-Itr-047875 Ictidomys tridecemlineatus 97.52 2.00e-175 608.00
IUUC-Lch-050563 Latimeria chalumnae 62.56 1.00e-104 372.00
IUUC-Laf-054589 Loxodonta africana 96.97 6.00e-147 513.00
IUUC-Mcc-055860 Macaca mulatta 99.72 9.00e-157 546.00
IUUC-Meu-056459 Macropus eugenii 93.95 7.00e-105 374.00
IUUC-Mmr-060819 Microcebus murinus 97.25 1.00e-167 582.00
IUUC-Mdo-062742 Monodelphis domestica 85.55 1.00e-144 505.00
IUUC-Mmu-063929 Mus musculus 94.77 4.00e-164 570.00
IUUC-Mac-065180 Musa acuminata 34.53 1.00e-43 171.00
IUUC-Mpu-066684 Mustela putorius furo 97.25 1.00e-157 548.00
IUUC-Mlu-067787 Myotis lucifugus 95.04 6.00e-152 530.00
IUUC-Nle-069846 Nomascus leucogenys 88.28 3.00e-136 478.00
IUUC-Ont-072271 Oreochromis niloticus 56.46 6.00e-89 320.00
IUUC-Oan-073572 Ornithorhynchus anatinus 80.17 2.00e-131 462.00
IUUC-Ocu-074968 Oryctolagus cuniculus 96.02 8.00e-106 378.00
IUUC-Oba-075392 Oryza barthii 38.71 4.00e-32 132.00
IUUC-Obr-076660 Oryza brachyantha 34.78 3.00e-45 176.00
IUUC-Ogu-078883 Oryza glumaepatula 38.71 4.00e-32 132.00
IUUC-Oin-079817 Oryza indica 38.71 4.00e-32 132.00
IUUC-Olo-080929 Oryza longistaminata 38.71 3.00e-32 132.00
IUUC-Ome-081866 Oryza meridionalis 38.71 3.00e-32 132.00
IUUC-Oni-083092 Oryza nivara 38.71 4.00e-32 132.00
IUUC-Opu-083756 Oryza punctata 39.44 7.00e-34 138.00
IUUC-Oru-084816 Oryza rufipogon 38.71 4.00e-32 132.00
IUUC-Osa-086112 Oryza sativa 38.71 4.00e-32 132.00
IUUC-Oga-089075 Otolemur garnettii 96.97 8.00e-150 523.00
IUUC-Oar-090387 Ovis aries 95.87 9.00e-146 509.00
IUUC-Ptr-090912 Pan troglodytes 96.42 9.00e-147 513.00
IUUC-Pan-092140 Papio anubis 99.72 5.00e-156 543.00
IUUC-Psi-093347 Pelodiscus sinensis 66.87 1.00e-67 249.00
IUUC-Pno-095064 Phaeosphaeria nodorum 36.82 7.00e-18 85.10
IUUC-Ppa-095654 Physcomitrella patens 40.00 3.00e-35 142.00
IUUC-Pfo-096607 Poecilia formosa 64.29 2.00e-95 342.00
IUUC-Pab-097738 Pongo abelii 96.14 6.00e-151 526.00
IUUC-Pca-100348 Procavia capensis 93.96 4.00e-145 507.00
IUUC-Ppe-101522 Prunus persica 33.50 6.00e-50 191.00
IUUC-Pva-102412 Pteropus vampyrus 96.97 3.00e-156 544.00
IUUC-Pgr-103618 Puccinia graminis 37.31 6.00e-25 108.00
IUUC-Rno-105569 Rattus norvegicus 95.04 2.00e-150 525.00
IUUC-Sha-106918 Sarcophilus harrisii 86.30 8.00e-131 460.00
IUUC-Sja-107851 Schizosaccharomyces japonicus 35.29 2.00e-43 169.00
IUUC-Smo-109129 Selaginella moellendorffii 38.65 4.00e-32 132.00
IUUC-Sit-109813 Setaria italica 35.94 1.00e-46 180.00
IUUC-Sbi-114459 Sorghum bicolor 32.03 8.00e-45 174.00
IUUC-Ssc-115460 Sus scrofa 96.69 2.00e-154 538.00
IUUC-Tsy-119385 Tarsius syrichta 81.62 3.00e-72 264.00
IUUC-Tni-120493 Tetraodon nigroviridis 60.17 3.00e-94 338.00
IUUC-Tre-121911 Trichoderma reesei 33.58 8.00e-28 117.00
IUUC-Tur-126610 Triticum urartu 38.11 1.00e-32 135.00
IUUC-Tbe-127603 Tupaia belangeri 84.67 4.00e-55 208.00
IUUC-Ttr-129232 Tursiops truncatus 86.78 1.00e-144 506.00
IUUC-Vda-129946 Verticillium dahliae 33.33 7.00e-21 94.70
Created Date 25-Jun-2017

https://dev.news.makassarkota.go.id/public/pgsoft-demo/ https://jdih.sumbawabaratkab.go.id/lato/pg-soft-demo/ https://dev.news.makassarkota.go.id/public/slot-gacor/ http://pbb.tanahbumbukab.go.id/-/slot-gacor/ slot gacor https://siakad.unipra.ac.id/sass/slot-gacor-x500/ http://kpm.dinus.ac.id/assets/images/berita/slot/
Copyright © 2004-2017.The CUCKOO Workgroup. All Rights Reserved