iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mcc-054833

UUCD1 version

UUC-MaM-00665

Ensembl Protein ID

ENSMMUP00000033987.2

UniProt Accession

F6V4V2; F7HF16; F6V4V2_MACMU

Genbank Protein ID

AFE65946.1; AFI35356.1

Protein Name

E3 ubiquitin-protein ligase RNF5

Genbank Nucleotide ID

JSUE03030649; JV045285

Gene Name

RNF5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000018438.3	ENSMMUT00000040959.2	ENSMMUP00000033987.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	5.50e-07	31.1	27	68

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iCle  ++  +v  CgH+++  Cl++w         ++ CP+C+
   Q: 27   CNICLETARE-AVVSVCGHLYCWPCLHQW---LETRPERQECPVCK 68
           99******88.888***************...555888889****7 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MAAAEEEDGG PEGPNRERGG AGATFECNIC LETAREAVVS VCGHLYCWPC LHQWLETRPE 60
RQECPVCKAG ISREKVVPLY GRGSQKPQDP RLKTPPRPQG QRPAPESRGA FQPFGDTGGF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAGCAG CGGAGGAGGA GGACGGGGGC CCCGAAGGGC CAAATCGCGA GCGGGGCGGG 60
GCGGGCGCGA CCTTCGAATG TAATATATGT TTGGAGACTG CTCGGGAAGC TGTGGTCAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0036513--C:Derlin-1 retrotranslocation complex
GO:0016021--C:integral component of membrane
GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0071712--P:ER-associated misfolded protein catabolic process
GO:0010507--P:negative regulation of autophagy
GO:0031648--P:protein destabilization
GO:0070936--P:protein K48-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:2000785--P:regulation of autophagosome assembly
GO:0009617--P:response to bacterium

KEGG

mcc:717234

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001155	Aegilops tauschii	48.54	1.00e-23	103.00
IUUC-Aml-001417	Ailuropoda melanoleuca	97.64	1.00e-70	258.00
IUUC-Atr-002444	Amborella trichopoda	50.89	7.00e-26	110.00
IUUC-Aca-004254	Anolis carolinensis	75.86	4.00e-36	143.00
IUUC-Aly-006065	Arabidopsis lyrata	54.12	2.00e-24	105.00
IUUC-Ath-007401	Arabidopsis thaliana	54.02	2.00e-24	105.00
IUUC-Ame-011316	Astyanax mexicanus	70.13	3.00e-57	214.00
IUUC-Bta-013109	Bos taurus	97.87	3.00e-79	287.00
IUUC-Bdi-014313	Brachypodium distachyon	54.65	1.00e-23	103.00
IUUC-Bol-016132	Brassica oleracea	42.86	2.00e-26	112.00
IUUC-Bra-017631	Brassica rapa	42.25	3.00e-26	111.00
IUUC-Cel-018228	Caenorhabditis elegans	47.74	2.00e-32	132.00
IUUC-Cja-019902	Callithrix jacchus	97.16	2.00e-78	284.00
IUUC-Cfa-020079	Canis familiaris	97.16	1.00e-78	285.00
IUUC-Cpo-021320	Cavia porcellus	92.81	7.00e-87	312.00
IUUC-Cre-022829	Chlamydomonas reinhardtii	54.55	2.00e-24	103.00
IUUC-Csa-023595	Chlorocebus sabaeus	100.00	1.00e-80	291.00
IUUC-Cme-027164	Cyanidioschyzon merolae	32.24	6.00e-17	81.30
IUUC-Dre-027716	Danio rerio	74.29	1.00e-42	166.00
IUUC-Dno-029843	Dasypus novemcinctus	83.69	5.00e-56	209.00
IUUC-Dor-030170	Dipodomys ordii	96.77	1.00e-68	251.00
IUUC-Eca-033642	Equus caballus	98.17	6.00e-92	329.00
IUUC-Eeu-034778	Erinaceus europaeus	97.44	1.00e-63	234.00
IUUC-Fca-036326	Felis catus	95.74	5.00e-78	283.00
IUUC-Fso-038195	Fusarium solani	40.91	3.00e-10	59.70
IUUC-Gac-042258	Gasterosteus aculeatus	80.00	5.00e-56	210.00
IUUC-Gma-043248	Glycine max	55.29	7.00e-25	107.00
IUUC-Ggo-045474	Gorilla gorilla	99.29	5.00e-80	289.00
IUUC-Hsa-046046	Homo sapiens	99.29	4.00e-80	290.00
IUUC-Hvu-047124	Hordeum vulgare	54.65	2.00e-23	102.00
IUUC-Itr-048037	Ictidomys tridecemlineatus	98.00	2.00e-84	304.00
IUUC-Lch-050367	Latimeria chalumnae	70.00	3.00e-45	173.00
IUUC-Lpe-051034	Leersia perrieri	58.14	2.00e-25	108.00
IUUC-Laf-053395	Loxodonta africana	95.74	1.00e-77	281.00
IUUC-Meu-055984	Macropus eugenii	86.08	5.00e-36	143.00
IUUC-Mtr-058107	Medicago truncatula	49.54	6.00e-25	107.00
IUUC-Mvi-060316	Microbotryum violaceum	43.75	9.00e-12	63.90
IUUC-Mdo-062437	Monodelphis domestica	87.80	1.00e-82	298.00
IUUC-Mmu-064159	Mus musculus	97.18	2.00e-79	288.00
IUUC-Mac-065053	Musa acuminata	57.65	8.00e-24	103.00
IUUC-Mlu-067689	Myotis lucifugus	91.98	2.00e-83	301.00
IUUC-Ncr-068628	Neurospora crassa	37.04	5.00e-09	55.80
IUUC-Nle-069705	Nomascus leucogenys	99.29	4.00e-80	290.00
IUUC-Opr-070392	Ochotona princeps	48.23	2.00e-24	104.00
IUUC-Ont-072482	Oreochromis niloticus	74.13	2.00e-58	218.00
IUUC-Ocu-074208	Oryctolagus cuniculus	96.45	7.00e-78	282.00
IUUC-Oba-075461	Oryza barthii	52.75	3.00e-24	105.00
IUUC-Obr-076382	Oryza brachyantha	56.98	7.00e-25	107.00
IUUC-Ogl-077553	Oryza glaberrima	56.25	2.00e-26	112.00
IUUC-Ogu-078463	Oryza glumaepatula	51.38	2.00e-26	112.00
IUUC-Oin-080177	Oryza indica	56.25	3.00e-26	111.00
IUUC-Olo-080378	Oryza longistaminata	54.65	1.00e-23	102.00
IUUC-Ome-081605	Oryza meridionalis	56.25	2.00e-26	112.00
IUUC-Oni-082458	Oryza nivara	56.25	5.00e-26	112.00
IUUC-Opu-083362	Oryza punctata	58.14	1.00e-25	110.00
IUUC-Oru-084757	Oryza rufipogon	55.00	8.00e-27	113.00
IUUC-Osa-086198	Oryza sativa	50.44	9.00e-27	114.00
IUUC-Ola-086507	Oryzias latipes	68.48	8.00e-61	226.00
IUUC-Olu-087623	Ostreococcus lucimarinus	49.25	2.00e-16	79.00
IUUC-Oga-088912	Otolemur garnettii	98.58	1.00e-79	288.00
IUUC-Oar-090284	Ovis aries	94.63	5.00e-71	259.00
IUUC-Ptr-090919	Pan troglodytes	99.21	1.00e-70	258.00
IUUC-Pan-092843	Papio anubis	100.00	1.00e-80	291.00
IUUC-Ppa-095474	Physcomitrella patens	50.50	1.00e-25	109.00
IUUC-Pfo-096818	Poecilia formosa	79.37	2.00e-56	211.00
IUUC-Pab-098244	Pongo abelii	98.58	1.00e-79	288.00
IUUC-Pop-099595	Populus trichocarpa	50.43	3.00e-27	115.00
IUUC-Pca-100319	Procavia capensis	96.34	1.00e-81	295.00
IUUC-Ppe-101752	Prunus persica	54.65	2.00e-24	105.00
IUUC-Pva-102249	Pteropus vampyrus	93.62	7.00e-73	266.00
IUUC-Rno-106042	Rattus norvegicus	97.18	2.00e-79	288.00
IUUC-Smo-109079	Selaginella moellendorffii	48.19	2.00e-22	100.00
IUUC-Sit-110690	Setaria italica	53.57	3.00e-22	98.20
IUUC-Sly-110917	Solanum lycopersicum	52.94	4.00e-25	107.00
IUUC-Stu-112117	Solanum tuberosum	49.59	2.00e-24	105.00
IUUC-Sbi-114275	Sorghum bicolor	54.65	2.00e-23	102.00
IUUC-Ssc-115934	Sus scrofa	98.58	1.00e-79	288.00
IUUC-Tru-118679	Takifugu rubripes	60.49	1.00e-22	98.20
IUUC-Tsy-119615	Tarsius syrichta	94.37	1.00e-74	271.00
IUUC-Tca-121830	Theobroma cacao	48.78	1.00e-25	109.00
IUUC-Tae-123623	Triticum aestivum	54.65	2.00e-23	102.00
IUUC-Tur-126198	Triticum urartu	54.65	2.00e-23	102.00
IUUC-Tbe-127773	Tupaia belangeri	95.74	7.00e-76	276.00
IUUC-Ttr-128690	Tursiops truncatus	96.58	2.00e-63	234.00
IUUC-Vda-129983	Verticillium dahliae	33.33	4.00e-08	50.80
IUUC-Vvi-131225	Vitis vinifera	60.00	6.00e-26	110.00
IUUC-Xtr-132608	Xenopus tropicalis	79.17	8.00e-45	172.00
IUUC-Xma-134225	Xiphophorus maculatus	79.37	1.00e-56	212.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence