iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tca-121574

Ensembl Protein ID

EOY07745

UniProt Accession

A0A061ESY5; A0A061ESY5_THECC

Genbank Protein ID

EOY07743.1; EOY07745.1

Protein Name

Ubiquitin protein ligase E3a, putative isoform 1

Genbank Nucleotide ID

CM001883; CM001883

Gene Name

TCM_022084

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TCM_022084	EOY07744	EOY07744
TCM_022084	EOY07745	EOY07745

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.00e-101	340.7	1195	1571

Active Site

Position(s)	Description	Evidence
1538	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 4    dlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysen...dketlqpnpdsglknp.....................ehlklFeflGrll 78
           + k  leve+ +E g++l G+t+ef++l+++e+q++ lg+++ + +    +etl +  + +l np                     e+lk F +lG+++
   Q: 1195 RHKGLLEVEYNEEVGTGL-GPTLEFYTLVCHEFQKSGLGIWREDYRsiiTSETLPVVDSGILINPyglfphpwspttdscngiqfsEVLKKFVLLGQIV 1292
           5567799***********.**********************76666666666666666666667788888999999999******************** PP
   S: 79   gkalqdgrlldlplsksfyklllgkklsledleevdpelykslkeikena...........esdieelgldltfsvseei.....lgetkeeeLkpgGe 161
           +ka+qdgr+ld+p+sk+fyk +lg++l l d+++++pel ++l e ++ +           e+++ +l+l+++ ++ e++     l+ + ++ L ++++
   Q: 1293 AKAIQDGRVLDVPFSKAFYKIILGQDLCLYDIQSFNPELGRTLLEFQAIVdrkmhlesicvENSTLKLDLCFRNTRIEDLcldftLPGYPDYVLSSECN 1391
           ******************************************999998885555555444433444555555555555557777799************ PP
   S: 162  nipVtneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevleefsse 259
           + +V+ +N+++Y+klvv++++++gi++qveaf++Gfn+v+ +++l +Ft eele l+cGe + + +++l +++k+++gyt++sp i++++e+++ef+  
   Q: 1392 HKMVNLANLDNYIKLVVDATIHTGIARQVEAFKSGFNQVFAIKHLHIFTGEELERLLCGErDFWAFNELLEHIKFDHGYTASSPPIINLLEIIQEFEYA 1490
           ************************************************************8889*********************************** PP
   S: 260  erkafLqFvTgssrlPlgGfaelkprlfvirk...dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kgFels 336
           +r+afLqFvTg +rlP+gG+a+l+p+l+++rk   +++d++lPs++TC+nyLkLP+Ysske +kekLlyAi+e+  +F+ls
   Q: 1491 QRRAFLQFVTGAPRLPPGGLASLNPKLTIVRKhssNSADTELPSVMTCANYLKLPPYSSKERMKEKLLYAITEGqGSFHLS 1571
           *********************************999999***********************************9999985 PP

Organism

Theobroma cacao

Protein Sequence
(Fasta)

MGNRGQKRTE TADELPADKR ACSSLEFRPS SSNSSSIQTH LNSPNSTPDA DMDTSSSASA 60
SSRSDGEHEK EEDSAYGSCD SEDAEQQPRH HILRDYQRRR SSSDHGKLNN ILSNLNEEGN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCGTTTAAA GGGTACCATT ATCATCCTTA ACCCAAAACA ATGAATCAAG ACGCACCGCT 60
GCACCGAAAG GAAATATGGT CTATTAATCG TACGGCCCAG ACTTCCGCAT CTTATCAAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000935	Aegilops tauschii	46.48	0.00e+00	1194.00
IUUC-Atr-002515	Amborella trichopoda	54.43	0.00e+00	677.00
IUUC-Aca-004521	Anolis carolinensis	35.05	6.00e-41	163.00
IUUC-Aly-006493	Arabidopsis lyrata	56.89	0.00e+00	1641.00
IUUC-Ath-006679	Arabidopsis thaliana	56.59	0.00e+00	1619.00
IUUC-Bdi-014101	Brachypodium distachyon	47.13	0.00e+00	1266.00
IUUC-Bol-016355	Brassica oleracea	56.04	0.00e+00	1577.00
IUUC-Bra-016937	Brassica rapa	54.29	0.00e+00	1476.00
IUUC-Dno-029954	Dasypus novemcinctus	35.05	2.00e-41	165.00
IUUC-Gma-043952	Glycine max	63.84	0.00e+00	1884.00
IUUC-Hvu-047811	Hordeum vulgare	46.97	0.00e+00	1292.00
IUUC-Lpe-051509	Leersia perrieri	56.06	0.00e+00	717.00
IUUC-Mtr-058626	Medicago truncatula	62.76	0.00e+00	1843.00
IUUC-Mga-059409	Meleagris gallopavo	35.74	1.00e-41	165.00
IUUC-Mac-065046	Musa acuminata	47.30	0.00e+00	1298.00
IUUC-Oba-075380	Oryza barthii	46.18	0.00e+00	1175.00
IUUC-Obr-076904	Oryza brachyantha	47.31	0.00e+00	1251.00
IUUC-Ogl-076926	Oryza glaberrima	47.62	0.00e+00	1281.00
IUUC-Ogu-078892	Oryza glumaepatula	47.33	0.00e+00	1234.00
IUUC-Oin-079148	Oryza indica	44.49	0.00e+00	1153.00
IUUC-Olo-081086	Oryza longistaminata	45.49	0.00e+00	1135.00
IUUC-Ome-081955	Oryza meridionalis	57.67	0.00e+00	740.00
IUUC-Oni-083047	Oryza nivara	45.69	0.00e+00	1199.00
IUUC-Opu-083641	Oryza punctata	46.23	0.00e+00	1212.00
IUUC-Oru-084439	Oryza rufipogon	46.04	0.00e+00	1170.00
IUUC-Osa-085617	Oryza sativa	60.98	0.00e+00	657.00
IUUC-Pop-099725	Populus trichocarpa	68.54	0.00e+00	2058.00
IUUC-Ppe-101229	Prunus persica	67.17	0.00e+00	2024.00
IUUC-Sit-110332	Setaria italica	46.06	0.00e+00	1275.00
IUUC-Sly-111552	Solanum lycopersicum	54.72	0.00e+00	1634.00
IUUC-Sbi-114106	Sorghum bicolor	45.60	0.00e+00	1251.00
IUUC-Tgu-117167	Taeniopygia guttata	35.40	3.00e-41	164.00
IUUC-Tae-125470	Triticum aestivum	47.69	0.00e+00	1282.00
IUUC-Tur-126486	Triticum urartu	53.30	0.00e+00	687.00
IUUC-Vvi-130904	Vitis vinifera	64.21	0.00e+00	1909.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence