iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
TRANSFAC
Protein-protein Interaction
iRefIndex	PINA	HINT	Mentha
Post-translational Modifications (PTMs)
dbPPT
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.30e-28	97.9	807	838

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sd.tllvsGsdDgtikvWDl 30
           H+ + ++++f  sd t +vsGsdD+++k+W++
   Q: 807  HQKRAWSVDFspSDpTKFVSGSDDCSVKLWSI 838
           888899*****9889***************96 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Controls normal photoperiodic flowering and regulates circadian rhythms. Required for suppression of photomorphogenesis in dark-grown seedlings and for normal elongation growth of adult plants. Integral component of the COP1/SPA E3 ubiquitin-protein ligase complex. Involved in HY5, HFR1, LAF1 and CO degradation.

Protein Sequence
(Fasta)

MPVMERVAEE TVATNNIQLK ARVDDVPCNK LDARHNDMVI QSETANSDCP GSSAHRNVDL 60
TKPPPPEEAA GAKLSVEELT LGNYRIVQGS NNTNVDSPRA GKFEHLYRLA RGSAFRAGDG 120

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Nucleotide Sequence
(Fasta)

GAAAAAATTA AATAAAATAA TGTTCAAAAA ATTGTCCGCC AGAATAAAGA AAATTTGATA 60
TGTGGCTTCA AAGCCTAAAT TAATCATTAA AATAAAAAAT CAGAAAATAA GGAATGAAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-0539--Nucleus
KW-0607--Phytochrome signaling pathway
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50011--PROTEIN_KINASE_DOM
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00069--Pkinase
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0016604--C:nuclear body
GO:0016607--C:nuclear speck
GO:0005634--C:nucleus
GO:0016605--C:PML body
GO:0005524--F:ATP binding
GO:0042802--F:identical protein binding
GO:0004672--F:protein kinase activity
GO:0009658--P:chloroplast organization
GO:0010100--P:negative regulation of photomorphogenesis
GO:0009640--P:photomorphogenesis
GO:0010017--P:red or far-red light signaling pathway
GO:0009585--P:red, far-red light phototransduction
GO:2000028--P:regulation of photoperiodism, flowering
GO:0009637--P:response to blue light
GO:0010218--P:response to far red light
GO:0010114--P:response to red light
GO:0048575--P:short-day photoperiodism, flowering

KEGG

ath:AT2G46340

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000403	Aegilops tauschii	47.52	0.00e+00	763.00
IUUC-Atr-002506	Amborella trichopoda	44.01	0.00e+00	708.00
IUUC-Aly-005520	Arabidopsis lyrata	93.51	0.00e+00	1978.00
IUUC-Bdi-014698	Brachypodium distachyon	46.67	0.00e+00	752.00
IUUC-Bol-015589	Brassica oleracea	76.13	0.00e+00	1434.00
IUUC-Bra-016642	Brassica rapa	81.73	0.00e+00	1591.00
IUUC-Gma-043294	Glycine max	48.43	0.00e+00	772.00
IUUC-Hvu-047750	Hordeum vulgare	46.51	0.00e+00	764.00
IUUC-Lpe-051349	Leersia perrieri	47.80	0.00e+00	787.00
IUUC-Mac-064712	Musa acuminata	46.94	0.00e+00	788.00
IUUC-Oba-075097	Oryza barthii	41.02	5.00e-177	614.00
IUUC-Obr-076441	Oryza brachyantha	47.97	0.00e+00	780.00
IUUC-Ogl-077669	Oryza glaberrima	47.08	0.00e+00	787.00
IUUC-Ogu-078009	Oryza glumaepatula	41.66	1.00e-178	620.00
IUUC-Oin-079775	Oryza indica	47.08	0.00e+00	788.00
IUUC-Olo-080230	Oryza longistaminata	40.94	3.00e-176	612.00
IUUC-Ome-081669	Oryza meridionalis	41.33	7.00e-177	613.00
IUUC-Oni-082065	Oryza nivara	41.13	8.00e-178	617.00
IUUC-Opu-083153	Oryza punctata	40.96	3.00e-177	615.00
IUUC-Oru-084928	Oryza rufipogon	41.13	2.00e-177	616.00
IUUC-Osa-085875	Oryza sativa	47.08	0.00e+00	788.00
IUUC-Pop-099610	Populus trichocarpa	48.52	0.00e+00	837.00
IUUC-Ppe-101782	Prunus persica	51.18	0.00e+00	877.00
IUUC-Sly-111623	Solanum lycopersicum	45.67	0.00e+00	793.00
IUUC-Stu-112382	Solanum tuberosum	46.36	0.00e+00	808.00
IUUC-Sbi-114133	Sorghum bicolor	47.94	0.00e+00	735.00
IUUC-Tca-121762	Theobroma cacao	52.30	0.00e+00	898.00
IUUC-Tae-125695	Triticum aestivum	47.69	0.00e+00	781.00
IUUC-Tur-126357	Triticum urartu	44.95	0.00e+00	721.00
IUUC-Vvi-131450	Vitis vinifera	49.51	0.00e+00	885.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence