iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bta-013545

Ensembl Protein ID

ENSBTAP00000045078.3

UniProt Accession

E1B7H4; E1B7H4_BOVIN

Genbank Protein ID

ENSBTAP00000045078

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02047073

Gene Name

MAP3K10

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000017618.5	ENSBTAT00000047929.3	ENSBTAP00000045078.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.90e-14	53.5	22	77

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlvieke...eqdegWlkgvkelegkrGlfPenFve 60
            + +dyea+ ++eLtl++Gd v+v++++   + degW+ g+   +g+ G+fP+n+v+
   Q: 22   TAVFDYEAAGEEELTLRRGDRVQVLSQDcavSGDEGWWTGQ-LPSGRVGVFPSNYVA 77
           589**********************77622257*******7.99***********96 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MEEEEWGAAK EWGTTPAGPV WTAVFDYEAA GEEELTLRRG DRVQVLSQDC AVSGDEGWWT 60
GQLPSGRVGV FPSNYVALGT PAAPAGLQLP QEIPFHELQL EEIIGVGGFG KVYRALWRGE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGGAGG AGGAGTGGGG GGCGGCCAAG GAGTGGGGCA CGACCCCCGC GGGGCCCGTC 60
TGGACCGCAG TGTTCGACTA CGAGGCGGCG GGCGAAGAGG AGCTGACCCT GCGGAGGGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011009--Kinase-like_dom
IPR015785--MAP3K10
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR008271--Ser/Thr_kinase_AS
IPR001452--SH3_domain

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00220--S_TKc
SM00326--SH3

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0004706--F:JUN kinase kinase kinase activity
GO:0003714--F:transcription corepressor activity
GO:0007257--P:activation of JUN kinase activity
GO:0043433--P:negative regulation of sequence-specific DNA binding transcription factor activity
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0018105--P:peptidyl-serine phosphorylation
GO:0018107--P:peptidyl-threonine phosphorylation
GO:0043065--P:positive regulation of apoptotic process
GO:0007224--P:smoothened signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001187	Ailuropoda melanoleuca	98.31	0.00e+00	828.00
IUUC-Atr-002478	Amborella trichopoda	33.33	8.00e-24	105.00
IUUC-Aly-006459	Arabidopsis lyrata	32.74	3.00e-28	120.00
IUUC-Ath-006581	Arabidopsis thaliana	32.38	1.00e-27	118.00
IUUC-Bdi-014449	Brachypodium distachyon	32.36	3.00e-25	110.00
IUUC-Bol-016287	Brassica oleracea	31.90	4.00e-27	116.00
IUUC-Bra-016997	Brassica rapa	32.97	2.00e-27	118.00
IUUC-Cja-019696	Callithrix jacchus	97.29	0.00e+00	824.00
IUUC-Cpo-021993	Cavia porcellus	98.04	0.00e+00	830.00
IUUC-Cre-022669	Chlamydomonas reinhardtii	33.64	1.00e-19	90.90
IUUC-Csa-024243	Chlorocebus sabaeus	97.70	0.00e+00	860.00
IUUC-Cho-024961	Choloepus hoffmanni	93.33	2.00e-113	402.00
IUUC-Dno-029095	Dasypus novemcinctus	97.46	0.00e+00	825.00
IUUC-Fca-036250	Felis catus	98.54	0.00e+00	843.00
IUUC-Gma-043336	Glycine max	29.90	6.00e-26	112.00
IUUC-Ggo-045471	Gorilla gorilla	97.92	0.00e+00	837.00
IUUC-Hsa-046936	Homo sapiens	97.91	0.00e+00	835.00
IUUC-Hvu-047798	Hordeum vulgare	32.27	2.00e-24	107.00
IUUC-Itr-048231	Ictidomys tridecemlineatus	97.86	0.00e+00	835.00
IUUC-Mcc-055733	Macaca mulatta	97.70	0.00e+00	859.00
IUUC-Mtr-058733	Medicago truncatula	32.59	4.00e-26	113.00
IUUC-Mmu-064082	Mus musculus	97.63	0.00e+00	837.00
IUUC-Mac-065156	Musa acuminata	31.93	1.00e-27	118.00
IUUC-Mpu-065934	Mustela putorius furo	98.33	0.00e+00	843.00
IUUC-Mlu-068137	Myotis lucifugus	91.97	0.00e+00	770.00
IUUC-Opr-070869	Ochotona princeps	78.88	0.00e+00	695.00
IUUC-Ocu-074350	Oryctolagus cuniculus	97.18	0.00e+00	813.00
IUUC-Oba-075616	Oryza barthii	34.88	2.00e-24	108.00
IUUC-Obr-076215	Oryza brachyantha	34.91	1.00e-25	112.00
IUUC-Ogl-077159	Oryza glaberrima	34.88	1.00e-24	108.00
IUUC-Ogu-078228	Oryza glumaepatula	35.35	5.00e-25	109.00
IUUC-Oin-079079	Oryza indica	34.93	4.00e-25	110.00
IUUC-Olo-080886	Oryza longistaminata	35.07	3.00e-24	106.00
IUUC-Oni-082188	Oryza nivara	34.27	1.00e-23	105.00
IUUC-Opu-083527	Oryza punctata	35.35	1.00e-24	108.00
IUUC-Oru-084678	Oryza rufipogon	34.93	4.00e-25	110.00
IUUC-Osa-086117	Oryza sativa	34.93	4.00e-25	110.00
IUUC-Oga-088351	Otolemur garnettii	97.65	0.00e+00	846.00
IUUC-Ptr-091607	Pan troglodytes	97.91	0.00e+00	835.00
IUUC-Pan-092403	Papio anubis	95.52	0.00e+00	833.00
IUUC-Pab-098396	Pongo abelii	97.91	0.00e+00	837.00
IUUC-Pop-100071	Populus trichocarpa	32.22	7.00e-24	105.00
IUUC-Ppe-101208	Prunus persica	34.76	4.00e-26	113.00
IUUC-Pva-103086	Pteropus vampyrus	96.60	0.00e+00	640.00
IUUC-Rno-105688	Rattus norvegicus	97.85	0.00e+00	838.00
IUUC-Smo-109113	Selaginella moellendorffii	32.72	8.00e-26	110.00
IUUC-Sit-110427	Setaria italica	34.58	8.00e-25	108.00
IUUC-Sly-111849	Solanum lycopersicum	35.09	2.00e-25	111.00
IUUC-Stu-112224	Solanum tuberosum	35.09	4.00e-25	110.00
IUUC-Sbi-113963	Sorghum bicolor	35.05	2.00e-25	111.00
IUUC-Ssc-115332	Sus scrofa	99.15	0.00e+00	861.00
IUUC-Tsy-119412	Tarsius syrichta	92.65	4.00e-70	259.00
IUUC-Tca-121565	Theobroma cacao	35.38	9.00e-26	112.00
IUUC-Tae-125555	Triticum aestivum	32.73	2.00e-24	107.00
IUUC-Tur-126322	Triticum urartu	32.26	3.00e-25	110.00
IUUC-Tbe-127643	Tupaia belangeri	97.70	0.00e+00	670.00
IUUC-Ttr-128550	Tursiops truncatus	97.91	0.00e+00	867.00
IUUC-Vvi-131057	Vitis vinifera	32.70	3.00e-23	104.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence