iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000032199.2	ENSGALT00000070756.1	ENSGALP00000047108.1
ENSGALG00000032199.2	ENSGALT00000063550.2	ENSGALP00000043829.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	9.00e-16	58.0	85	141

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           ++++lydyea ++d+L+++kG++ ++i  ++++++W+++ +  +g  G +P+n+v+ ++
   Q: 85   LFIALYDYEARTEDDLSFQKGEKFHII--NNTEGDWWEARSLSSGATGYIPSNYVAPVD 141
           5789***********************..8999**********************9987 PP

Organism

Gallus gallus

Functional Description
(View)

ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.

Protein Sequence
(Fasta)

MGCVHCKEKI SGKGQGGSGT GTPAHPPSQY DPDPTQLSGA FTHIPDFNNF HAAAVSPPVP 60
FSGPGFYPCN TLQAHSSITG GGVTLFIALY DYEARTEDDL SFQKGEKFHI INNTEGDWWE 120

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Nucleotide Sequence
(Fasta)

GGCAACGGGG GAACCGCACG CACCGCTCCG CCTCTCCCCG CACTGTGCCC CGCAGCGCTG 60
TGCCCGGCCC CGGTGGGGGG GGTCGGGGTG CAGCCCCGGG GGGGCTCCAT GCGAAGAGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0449--Lipoprotein
KW-0519--Myristate
KW-0547--Nucleotide-binding
KW-0564--Palmitate
KW-0597--Phosphoprotein
KW-0656--Proto-oncogene
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0031234--C:extrinsic component of cytoplasmic side of plasma membrane
GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0005102--F:receptor binding
GO:0030154--P:cell differentiation
GO:0016477--P:cell migration
GO:0045087--P:innate immune response
GO:0007229--P:integrin-mediated signaling pathway
GO:0038083--P:peptidyl-tyrosine autophosphorylation
GO:0042127--P:regulation of cell proliferation
GO:0007169--P:transmembrane receptor protein tyrosine kinase signaling pathway

KEGG

gga:777583

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-004483	Anolis carolinensis	87.71	0.00e+00	958.00
IUUC-Ame-011816	Astyanax mexicanus	79.30	0.00e+00	872.00
IUUC-Dre-028216	Danio rerio	81.30	0.00e+00	895.00
IUUC-Fal-036786	Ficedula albicollis	92.64	0.00e+00	964.00
IUUC-Lpe-051166	Leersia perrieri	35.82	1.00e-23	104.00
IUUC-Loc-052620	Lepisosteus oculatus	83.67	0.00e+00	926.00
IUUC-Meu-056155	Macropus eugenii	78.85	0.00e+00	731.00
IUUC-Ogl-077331	Oryza glaberrima	35.82	8.00e-24	105.00
IUUC-Ogu-078962	Oryza glumaepatula	35.82	9.00e-24	105.00
IUUC-Oin-079172	Oryza indica	35.82	8.00e-24	105.00
IUUC-Olo-080286	Oryza longistaminata	35.82	8.00e-24	105.00
IUUC-Ome-081400	Oryza meridionalis	35.82	8.00e-24	105.00
IUUC-Oru-084741	Oryza rufipogon	35.82	8.00e-24	105.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence