iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mac-065499

Ensembl Protein ID

GSMUA_Achr6P12350_001

UniProt Accession

M0T6D3; M0T6D3_MUSAM

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
GSMUA_Achr6G12350_001	GSMUA_Achr6T12350_001	GSMUA_Achr6P12350_001

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.80e-120	403.2	3230	3569
UBD/Alpha-Helix/UBM	3.60e-13	49.6	2528	2552
UBD/Alpha-Helix/UBA	2.40e-08	34.7	1273	1312

Active Site

Position(s)	Description	Evidence
3537	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrl 87
           ++dlk +l v+f+gEeg+d+gG+tre+++lls+ ++++ + lf+ + ++++t+qpnp+s ++ +ehl++F+f+Gr++gkal+d++l
   Q: 3230 PHDLKGKLTVHFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFT-TVGNESTFQPNPNSVYQ-TEHLSYFKFVGRVVGKALFDSQL 3313
           689************************************99995.55577788******986.5********************** PP
   S: 88   ldlplsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseei.......lgetkeeeLkpgGenipVt 166
           ld+++++sfyk++lg+k++++d+e+vdp++yk+lk+++en   di++  ld+tfs++ ++         e+++ eL+pgG+ni+Vt
   Q: 3314 LDVHFTRSFYKHILGVKVTYHDIEAVDPDYYKNLKWMLEN---DISDV-LDVTFSMDADEeklilyeRAEVTDCELIPGGRNIRVT 3395
           **************************************99...89997.99999977766679995444455556*********** PP
   S: 167  neNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwev 252
           +eNk+eYv++v+e+ l++ i+ q++af eGf+e+ip +l+s+F+ +elelli+G ++id++dl+++t+y +gy++ sp+iqwFwev
   Q: 3396 EENKHEYVDRVAEHLLTTAIRPQINAFMEGFTELIPRDLISIFNDKELELLISGLPDIDLDDLRANTEY-SGYSNASPVIQWFWEV 3480
           *********************************************************************.55************** PP
   S: 253  leefsseerkafLqFvTgssrlPlgGfaelk....prlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kg 332
           +++fs+e++++fLqFvTg+s++Pl+Gf +l+     ++f+i+k ++++++lPs++TCfn+L+LPeY+ske+l+e+Ll+Ai+e+ +g
   Q: 3481 VQGFSKEDKARFLQFVTGTSKVPLEGFSALQgisgSQRFQIHKaYGTPHHLPSAHTCFNQLDLPEYTSKEQLEERLLLAIHEAnEG 3566
           ***********************************999*****99999***********************************9** PP
   S: 333  Fel 335
           F++
   Q: 3567 FGF 3569
           *85 PP

UBD/Alpha-Helix/UBM

   S: 4    qvDpeVfsqLPeeiQeEvmaelrqq 28
           ++Dpe++++LP++i+eEv+a +r q
   Q: 2528 DIDPEFLAALPPDIREEVLAQQRAQ 2552
           79******************99976 PP

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGFdreealqaLraa.nnnleaAveyLldg 41
           de++++ +veMGF+r +a +aLr+   n++e A+++L+++
   Q: 1273 DESAIALIVEMGFSRARAEEALRQVgTNSVEIATDWLFSH 1312
           89************************************97 PP

Organism

Musa acuminata

Protein Sequence
(Fasta)

MAGNRSNLPL RLQQILSGGR SVSPVLKLES EPPPKVKAFI DRVIKSPLHD IAIPLSGFRW 60
EFKKGNFNHW RPLFVHFDTY FKTYLSCRKD LLLLDHMSDE DPFPKHSVMQ ILRVMQIIFE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAGGGA ACCGGTCGAA TCTGCCCTTG CGACTGCAGC AGATCTTATC CGGCGGGAGG 60
TCCGTCTCGC CGGTGCTTAA ATTGGAGTCC GAGCCCGTGA GTTCTCCCTG GATTAAACCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR025527--DUF4414
IPR010309--E3_Ub_ligase_DUF908
IPR010314--E3_Ub_ligase_DUF913
IPR000569--HECT_dom
IPR015940--UBA
IPR009060--UBA-like
IPR003903--UIM_dom

PROSITE

PS50237--HECT
PS50030--UBA
PS50330--UIM

Pfam

PF14377--DUF4414
PF06012--DUF908
PF06025--DUF913
PF00632--HECT
PF00627--UBA

SMART

SM00119--HECTc
SM00165--UBA

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000627	Aegilops tauschii	65.88	0.00e+00	4164.00
IUUC-Atr-002582	Amborella trichopoda	59.94	0.00e+00	2462.00
IUUC-Aly-006157	Arabidopsis lyrata	57.39	0.00e+00	2252.00
IUUC-Bdi-014884	Brachypodium distachyon	67.67	0.00e+00	4361.00
IUUC-Bol-015228	Brassica oleracea	56.20	0.00e+00	1904.00
IUUC-Bra-016726	Brassica rapa	55.32	0.00e+00	2006.00
IUUC-Dse-031197	Dothistroma septosporum	31.78	8.00e-135	476.00
IUUC-Gma-042956	Glycine max	59.34	0.00e+00	2485.00
IUUC-Hvu-047697	Hordeum vulgare	67.66	0.00e+00	4335.00
IUUC-Lpe-051550	Leersia perrieri	67.70	0.00e+00	4269.00
IUUC-Meu-056751	Macropus eugenii	44.55	5.00e-77	283.00
IUUC-Mtr-057633	Medicago truncatula	60.77	0.00e+00	2388.00
IUUC-Opr-071044	Ochotona princeps	44.25	9.00e-91	327.00
IUUC-Oba-075757	Oryza barthii	67.89	0.00e+00	4272.00
IUUC-Obr-076553	Oryza brachyantha	68.42	0.00e+00	4362.00
IUUC-Ogl-077520	Oryza glaberrima	68.19	0.00e+00	4392.00
IUUC-Ogu-078278	Oryza glumaepatula	67.12	0.00e+00	4318.00
IUUC-Oin-079767	Oryza indica	68.64	0.00e+00	4406.00
IUUC-Olo-080380	Oryza longistaminata	66.73	0.00e+00	4304.00
IUUC-Ome-081925	Oryza meridionalis	68.14	0.00e+00	4375.00
IUUC-Oni-082619	Oryza nivara	64.74	0.00e+00	4130.00
IUUC-Opu-083684	Oryza punctata	66.65	0.00e+00	4271.00
IUUC-Oru-084501	Oryza rufipogon	68.30	0.00e+00	4395.00
IUUC-Ppa-095834	Physcomitrella patens	37.70	0.00e+00	1181.00
IUUC-Pop-099468	Populus trichocarpa	64.16	0.00e+00	4129.00
IUUC-Ppe-101641	Prunus persica	61.31	0.00e+00	2305.00
IUUC-Sit-110598	Setaria italica	67.35	0.00e+00	4288.00
IUUC-Sly-111706	Solanum lycopersicum	57.04	0.00e+00	2206.00
IUUC-Sbi-114042	Sorghum bicolor	67.13	0.00e+00	4302.00
IUUC-Tsy-119407	Tarsius syrichta	47.31	4.00e-94	338.00
IUUC-Tca-121479	Theobroma cacao	61.79	0.00e+00	3973.00
IUUC-Tae-125214	Triticum aestivum	65.16	0.00e+00	2252.00
IUUC-Tbe-127762	Tupaia belangeri	42.04	8.00e-83	302.00
IUUC-Vvi-131078	Vitis vinifera	63.36	0.00e+00	2187.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence