iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
TRANSFAC
Post-translational Modifications (PTMs)
dbPPT
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 activity/RING/U-box	U-box	14657406

Classification

Family	E-value	Score	Start	End
E3 activity/RING/U-box	6.10e-28	97.6	290	360
E3 activity/RING/RING	0.012	17.0	294	331

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceenss 74
           e++lCpIsle+M+dPvv+++G+tydrssI kw+ sg+ tcP+t++ lt+++lv+n ++r++i ++c++n++
   Q: 290  EDLLCPISLEIMTDPVVIETGHTYDRSSITKWFGSGNITCPITGKILTSTELVDNVSVRQVIRKHCKTNGI 360
           789*****************************************************************985 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPl 44
           C+i le + d p+v   gH++ ++ + kw     + s++++CP+
   Q: 294  CPISLEIMTD-PVVIETGHTYDRSSITKW-----FGSGNITCPI 331
           **********.999***************.....9********6 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Functions as an E3 ubiquitin ligase.

Protein Sequence
(Fasta)

MIHTKTGSGR RILTFPTVEP SESISIVTLL DSLIQLAGDI LTFKSKHFST NKQSFRETLR 60
RIQNLLVVFE EIRIRIRNSR RYFHDSAAAS SLKEIHVGFQ KLKFLLEDCT RDGARLCMMM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTTCCTCGT TTTCGACGGA TCTCACGTGG CACTCTGTCA GTGGTCAGGG TTTCCAAGTA 60
ACATTGTCCA ATGATACACC ACCACGCGCT CTAATTAAAG TTGAAACCTT TGTCAACTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR000225--Armadillo
IPR003613--Ubox_domain
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50176--ARM_REPEAT
PS51698--U_BOX

Pfam

PF00514--Arm
PF04564--U-box

SMART

SM00185--ARM
SM00504--Ubox

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0016567--P:protein ubiquitination
GO:0010029--P:regulation of seed germination

KEGG

ath:AT1G10560

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-006201	Arabidopsis lyrata	91.10	0.00e+00	1247.00
IUUC-Bol-015964	Brassica oleracea	78.71	0.00e+00	1071.00
IUUC-Bra-017789	Brassica rapa	77.60	0.00e+00	1028.00
IUUC-Lpe-051010	Leersia perrieri	36.82	9.00e-77	280.00
IUUC-Loc-051960	Lepisosteus oculatus	27.17	8.00e-13	67.80
IUUC-Obr-076695	Oryza brachyantha	38.10	4.00e-62	231.00
IUUC-Ogl-077133	Oryza glaberrima	39.12	1.00e-80	293.00
IUUC-Ogu-078633	Oryza glumaepatula	38.46	2.00e-80	292.00
IUUC-Oin-079248	Oryza indica	38.02	3.00e-79	289.00
IUUC-Ome-081678	Oryza meridionalis	38.46	6.00e-80	291.00
IUUC-Oni-082545	Oryza nivara	38.24	4.00e-80	291.00
IUUC-Oru-084317	Oryza rufipogon	38.24	7.00e-80	291.00
IUUC-Osa-085294	Oryza sativa	38.02	2.00e-79	289.00
IUUC-Sly-111130	Solanum lycopersicum	41.88	1.00e-148	519.00
IUUC-Tru-118470	Takifugu rubripes	24.55	2.00e-09	56.60

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence