iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004619

UUCD1 version

UUC-AnC-00167

Ensembl Protein ID

ENSACAP00000006486.3

UniProt Accession

H9GBQ2; H9GBQ2_ANOCA

Protein Name

Uncharacterized protein

Gene Name

RFWD3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000006627.3	ENSACAT00000006631.3	ENSACAP00000006486.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.40e-08	34.6	421	459
E3 activity/RING/RING	2.60e-06	27.8	213	257

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf...sdtllvsGsdDgtikvWDlrtgvllk 37
           H+  +++laf    d+ll+s++ D+t+k+ +l+t+++++
   Q: 421  HNKQIRGLAFsnrADGLLLSAALDHTLKLTSLTTNTVVQ 459
           8999******98756**************9999998887 PP

E3 activity/RING/RING

   S: 1    CaiCledf.....kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           CaiC+e+         +  l+CgH+f  +C+q+w     ++ ++ +CP C+
   Q: 213  CAICFEEWtnageH-RLSALRCGHLFGYSCIQRW-----LKGQAGKCPQCN 257
           ******99777633.38889**************.....4555559***96 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MAQEAMEVDL LPAAEEAGRP SGEGRGASGS GAGPGPLAGP GPASPRPSWA AFSGEAEPRR 60
PPPPPRARGN RARRAPRAAP GRATAPLESY FQVSRTQATD PSDVLAVLNR NSSDEPVVLS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCTGAGCTG CCCAATGGGA AATAGTAGCG GGAGCGGTGC CCAATAGGAA CCGCCGCACG 60
CAGGAGAGCG ACCAATGGGG GCGGGAGGCG GGTCCTGAGT GGCGGCGGGG AGATTGAGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING
SM00320--WD40

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0035861--C:site of double-strand break
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0031571--P:mitotic G1 DNA damage checkpoint
GO:2000001--P:regulation of DNA damage checkpoint
GO:0010212--P:response to ionizing radiation

KEGG

acs:100565467

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000929	Aegilops tauschii	25.63	6.00e-19	89.00
IUUC-Aml-001188	Ailuropoda melanoleuca	63.29	0.00e+00	767.00
IUUC-Atr-003034	Amborella trichopoda	29.24	1.00e-17	83.60
IUUC-Apl-003182	Anas platyrhynchos	80.43	0.00e+00	850.00
IUUC-Aly-006391	Arabidopsis lyrata	27.07	4.00e-33	135.00
IUUC-Ath-007300	Arabidopsis thaliana	27.91	1.00e-36	147.00
IUUC-Ame-010890	Astyanax mexicanus	66.06	0.00e+00	681.00
IUUC-Bta-013051	Bos taurus	67.05	0.00e+00	746.00
IUUC-Bdi-014519	Brachypodium distachyon	25.98	2.00e-23	103.00
IUUC-Bol-015271	Brassica oleracea	28.82	3.00e-35	142.00
IUUC-Bra-017931	Brassica rapa	29.28	2.00e-35	144.00
IUUC-Cja-019240	Callithrix jacchus	61.74	0.00e+00	760.00
IUUC-Cfa-021010	Canis familiaris	62.72	0.00e+00	775.00
IUUC-Cpo-022308	Cavia porcellus	64.42	0.00e+00	697.00
IUUC-Csa-023501	Chlorocebus sabaeus	61.07	0.00e+00	758.00
IUUC-Cho-024900	Choloepus hoffmanni	56.89	0.00e+00	683.00
IUUC-Cin-025403	Ciona intestinalis	38.33	4.00e-99	355.00
IUUC-Csv-025819	Ciona savignyi	38.85	7.00e-46	176.00
IUUC-Cme-027123	Cyanidioschyzon merolae	25.87	5.00e-19	89.40
IUUC-Dre-028354	Danio rerio	61.30	2.00e-176	612.00
IUUC-Dno-029400	Dasypus novemcinctus	62.72	0.00e+00	775.00
IUUC-Dor-030320	Dipodomys ordii	54.62	0.00e+00	652.00
IUUC-Dme-031949	Drosophila melanogaster	25.99	2.00e-42	166.00
IUUC-Ete-032691	Echinops telfairi	57.14	8.00e-98	351.00
IUUC-Eca-034320	Equus caballus	62.30	0.00e+00	766.00
IUUC-Fca-035732	Felis catus	62.40	0.00e+00	770.00
IUUC-Fal-036648	Ficedula albicollis	80.16	0.00e+00	853.00
IUUC-Gmo-038609	Gadus morhua	60.62	2.00e-149	521.00
IUUC-Gga-040522	Gallus gallus	76.87	3.00e-127	448.00
IUUC-Gac-042318	Gasterosteus aculeatus	60.10	9.00e-147	512.00
IUUC-Gma-043184	Glycine max	41.77	3.00e-15	77.00
IUUC-Ggo-044464	Gorilla gorilla	60.74	0.00e+00	752.00
IUUC-Hsa-045991	Homo sapiens	60.90	0.00e+00	755.00
IUUC-Hvu-047705	Hordeum vulgare	25.10	1.00e-29	124.00
IUUC-Itr-047977	Ictidomys tridecemlineatus	60.13	0.00e+00	763.00
IUUC-Lch-050112	Latimeria chalumnae	71.59	0.00e+00	749.00
IUUC-Lpe-051605	Leersia perrieri	26.81	3.00e-18	86.70
IUUC-Loc-052241	Lepisosteus oculatus	68.90	0.00e+00	683.00
IUUC-Laf-054559	Loxodonta africana	59.97	0.00e+00	672.00
IUUC-Mcc-055093	Macaca mulatta	60.74	0.00e+00	751.00
IUUC-Meu-056417	Macropus eugenii	63.80	0.00e+00	668.00
IUUC-Mtr-058533	Medicago truncatula	29.52	1.00e-33	137.00
IUUC-Mga-059498	Meleagris gallopavo	71.32	0.00e+00	782.00
IUUC-Mmr-061782	Microcebus murinus	62.56	0.00e+00	759.00
IUUC-Mdo-062053	Monodelphis domestica	71.08	0.00e+00	758.00
IUUC-Mmu-063352	Mus musculus	63.95	0.00e+00	713.00
IUUC-Mac-064582	Musa acuminata	28.09	5.00e-27	115.00
IUUC-Mpu-066087	Mustela putorius furo	61.91	0.00e+00	758.00
IUUC-Mlu-068147	Myotis lucifugus	66.53	0.00e+00	709.00
IUUC-Nle-069503	Nomascus leucogenys	57.19	0.00e+00	696.00
IUUC-Opr-070479	Ochotona princeps	56.36	0.00e+00	682.00
IUUC-Ont-071700	Oreochromis niloticus	62.38	0.00e+00	650.00
IUUC-Oan-073702	Ornithorhynchus anatinus	77.22	0.00e+00	822.00
IUUC-Ocu-074886	Oryctolagus cuniculus	59.97	0.00e+00	738.00
IUUC-Oba-075729	Oryza barthii	28.25	4.00e-28	119.00
IUUC-Obr-076562	Oryza brachyantha	24.09	8.00e-20	91.70
IUUC-Ogl-077615	Oryza glaberrima	28.25	4.00e-28	119.00
IUUC-Ogu-078921	Oryza glumaepatula	28.25	1.00e-28	120.00
IUUC-Oin-079250	Oryza indica	24.54	2.00e-18	87.00
IUUC-Olo-080758	Oryza longistaminata	25.74	8.00e-27	114.00
IUUC-Ome-081707	Oryza meridionalis	24.49	2.00e-20	94.00
IUUC-Oni-083006	Oryza nivara	28.25	3.00e-28	120.00
IUUC-Opu-083650	Oryza punctata	27.18	7.00e-27	115.00
IUUC-Oru-084924	Oryza rufipogon	28.35	4.00e-29	122.00
IUUC-Osa-085820	Oryza sativa	28.25	3.00e-28	119.00
IUUC-Ola-087229	Oryzias latipes	62.14	1.00e-151	529.00
IUUC-Oga-088243	Otolemur garnettii	62.07	0.00e+00	745.00
IUUC-Oar-089461	Ovis aries	60.68	0.00e+00	751.00
IUUC-Ptr-090527	Pan troglodytes	60.74	0.00e+00	748.00
IUUC-Pan-092431	Papio anubis	60.31	0.00e+00	681.00
IUUC-Psi-093156	Pelodiscus sinensis	82.30	0.00e+00	917.00
IUUC-Ppa-095305	Physcomitrella patens	39.37	3.00e-22	100.00
IUUC-Pfo-097065	Poecilia formosa	62.30	5.00e-179	620.00
IUUC-Pab-098272	Pongo abelii	60.90	0.00e+00	754.00
IUUC-Pop-099827	Populus trichocarpa	29.71	1.00e-29	124.00
IUUC-Pca-100713	Procavia capensis	57.41	0.00e+00	639.00
IUUC-Ppe-102103	Prunus persica	26.60	5.00e-34	139.00
IUUC-Pva-103133	Pteropus vampyrus	67.23	4.00e-173	601.00
IUUC-Pte-104191	Pyrenophora teres	48.00	1.00e-07	50.10
IUUC-Pyt-104734	Pyrenophora triticirepentis	50.00	5.00e-08	51.60
IUUC-Sha-107628	Sarcophilus harrisii	70.75	0.00e+00	762.00
IUUC-Sit-109891	Setaria italica	25.14	1.00e-26	114.00
IUUC-Sly-111779	Solanum lycopersicum	29.16	1.00e-34	141.00
IUUC-Stu-112817	Solanum tuberosum	45.16	1.00e-21	96.70
IUUC-Sar-113124	Sorex araneus	60.60	2.00e-135	476.00
IUUC-Sbi-114107	Sorghum bicolor	26.05	8.00e-30	125.00
IUUC-Sre-115057	Sporisorium reilianum	34.78	5.00e-06	46.20
IUUC-Ssc-115850	Sus scrofa	61.92	0.00e+00	748.00
IUUC-Tgu-117295	Taeniopygia guttata	78.77	0.00e+00	835.00
IUUC-Tru-117539	Takifugu rubripes	62.80	0.00e+00	636.00
IUUC-Tsy-118805	Tarsius syrichta	54.92	2.00e-88	320.00
IUUC-Tni-120274	Tetraodon nigroviridis	63.84	0.00e+00	636.00
IUUC-Tca-121162	Theobroma cacao	26.64	6.00e-30	125.00
IUUC-Tae-124822	Triticum aestivum	28.21	5.00e-31	129.00
IUUC-Tur-126162	Triticum urartu	26.04	3.00e-21	96.70
IUUC-Tbe-127884	Tupaia belangeri	52.24	2.00e-55	210.00
IUUC-Ttr-128665	Tursiops truncatus	67.06	7.00e-107	381.00
IUUC-Uma-129349	Ustilago maydis	37.18	8.00e-07	48.50
IUUC-Vpa-130385	Vicugna pacos	62.42	0.00e+00	775.00
IUUC-Vvi-131464	Vitis vinifera	28.01	6.00e-28	118.00
IUUC-Xtr-132015	Xenopus tropicalis	64.32	0.00e+00	769.00
IUUC-Xma-133109	Xiphophorus maculatus	62.73	2.00e-178	619.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence