iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMUSG00000030598.15	ENSMUST00000032818.12	ENSMUSP00000032818.6
ENSMUSG00000030598.15	ENSMUST00000108279.8	ENSMUSP00000103914.2

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
microRNA	TRANSFAC	RepTar	RAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/SCF/F-box	83.57	2.00e-138	489.00	IUUC-Hsa-045768

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Mus musculus

Functional Description
(View)

Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Able to recognize and bind denatured glycoproteins, which are modified with complex-type oligosaccharides. Also recognizes sulfated glycans. Does not bind high-mannose glycoproteins (By similarity).

Protein Sequence
(Fasta)

MGARPSRRQM TEARRLALTK LPPELLVQVL SHVPPRALVT RCRPVCRAWR DLVDGPSIWL 60
LQLARDRSAE GRALYALAQR CPADADADAD ADGNRHDEFP FCALARFCLR APFGRNLIHN 120

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Nucleotide Sequence
(Fasta)

CACGTTTCAG GGACAGGCGG CCTAGCTCGG CGGCCCTGGG CCGGGCTCAC TCAGGCTGCA 60
ACGTTGCCCG GTGGCCCCGG GATCCTGAGC ATAGAAGAAG ACGGTCCACT AGGACCCCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR007397--F-box-assoc_dom
IPR001810--F-box_dom
IPR008979--Galactose-bd-like

PROSITE

PS51114--FBA
PS50181--FBOX

Pfam

PF12937--F-box-like
PF04300--FBA

SMART

SM01198--FBA
SM00256--FBOX

Gene Ontology

GO:0019005--C:SCF ubiquitin ligase complex
GO:0001948--F:glycoprotein binding
GO:0004842--F:ubiquitin-protein transferase activity

KEGG

mmu:50760

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000348	Aegilops tauschii	54.55	1.00e-05	44.70
IUUC-Aml-002175	Ailuropoda melanoleuca	88.08	5.00e-134	470.00
IUUC-Aca-005289	Anolis carolinensis	49.60	5.00e-64	237.00
IUUC-Aly-006011	Arabidopsis lyrata	37.31	2.00e-05	43.10
IUUC-Ath-007566	Arabidopsis thaliana	34.33	2.00e-03	37.00
IUUC-Bta-012403	Bos taurus	83.97	4.00e-134	470.00
IUUC-Bdi-014875	Brachypodium distachyon	32.86	3.00e-03	36.20
IUUC-Bol-016158	Brassica oleracea	34.78	2.90e-02	34.30
IUUC-Bra-016666	Brassica rapa	39.47	5.00e-04	38.50
IUUC-Cja-019664	Callithrix jacchus	81.60	7.00e-135	473.00
IUUC-Cfa-020507	Canis familiaris	84.27	2.00e-131	461.00
IUUC-Cpo-021692	Cavia porcellus	83.39	5.00e-135	473.00
IUUC-Csa-023237	Chlorocebus sabaeus	83.22	2.00e-138	484.00
IUUC-Dno-030010	Dasypus novemcinctus	83.01	2.00e-123	434.00
IUUC-Dor-030171	Dipodomys ordii	86.01	5.00e-142	496.00
IUUC-Eca-034121	Equus caballus	93.53	2.00e-74	270.00
IUUC-Eeu-034490	Erinaceus europaeus	77.27	1.00e-126	445.00
IUUC-Fca-036454	Felis catus	68.86	7.00e-103	366.00
IUUC-Gma-044203	Glycine max	35.71	6.00e-03	35.40
IUUC-Hsa-045768	Homo sapiens	83.57	2.00e-133	468.00
IUUC-Hvu-047581	Hordeum vulgare	42.11	5.60e-02	31.60
IUUC-Itr-048913	Ictidomys tridecemlineatus	94.44	3.00e-89	320.00
IUUC-Lpe-051277	Leersia perrieri	62.50	5.00e-03	32.30
IUUC-Laf-054235	Loxodonta africana	95.49	1.00e-72	264.00
IUUC-Mcc-054716	Macaca mulatta	73.78	2.00e-109	388.00
IUUC-Mtr-057739	Medicago truncatula	34.62	1.00e-04	40.80
IUUC-Mmr-061741	Microcebus murinus	86.92	8.00e-132	462.00
IUUC-Mac-064513	Musa acuminata	35.71	8.70e-02	31.20
IUUC-Mpu-066676	Mustela putorius furo	86.01	8.00e-137	479.00
IUUC-Mlu-067553	Myotis lucifugus	95.06	4.00e-89	319.00
IUUC-Nle-069434	Nomascus leucogenys	83.22	2.00e-132	464.00
IUUC-Opr-070811	Ochotona princeps	80.85	2.00e-63	235.00
IUUC-Ocu-074614	Oryctolagus cuniculus	82.44	4.00e-121	427.00
IUUC-Ogl-077337	Oryza glaberrima	39.53	3.00e-03	35.80
IUUC-Ogu-078768	Oryza glumaepatula	40.00	1.00e-04	40.80
IUUC-Oin-079568	Oryza indica	39.53	1.00e-03	36.20
IUUC-Olo-080883	Oryza longistaminata	45.65	4.00e-07	47.40
IUUC-Ome-081576	Oryza meridionalis	33.93	9.00e-06	45.10
IUUC-Oni-082669	Oryza nivara	33.96	1.00e-05	44.70
IUUC-Opu-083853	Oryza punctata	36.73	2.00e-04	40.40
IUUC-Oru-084840	Oryza rufipogon	33.96	1.00e-05	45.10
IUUC-Osa-086099	Oryza sativa	36.17	2.00e-04	40.40
IUUC-Oga-088143	Otolemur garnettii	83.22	5.00e-138	483.00
IUUC-Oar-089201	Ovis aries	92.59	1.00e-86	311.00
IUUC-Pan-092112	Papio anubis	83.57	6.00e-133	466.00
IUUC-Pab-098059	Pongo abelii	83.22	3.00e-139	487.00
IUUC-Pop-100065	Populus trichocarpa	38.78	1.00e-05	43.90
IUUC-Pca-100353	Procavia capensis	72.82	1.00e-116	412.00
IUUC-Ppe-101505	Prunus persica	29.69	4.00e-04	39.30
IUUC-Pva-102310	Pteropus vampyrus	82.52	3.00e-131	460.00
IUUC-Rno-105558	Rattus norvegicus	87.55	8.00e-115	406.00
IUUC-Sit-109871	Setaria italica	31.37	5.00e-03	37.00
IUUC-Sly-111384	Solanum lycopersicum	34.62	5.00e-04	39.30
IUUC-Sar-113465	Sorex araneus	68.78	3.00e-82	297.00
IUUC-Sbi-114168	Sorghum bicolor	50.00	6.80e-02	32.30
IUUC-Ssc-115935	Sus scrofa	62.07	4.00e-94	337.00
IUUC-Tca-121064	Theobroma cacao	42.11	1.00e-04	40.80
IUUC-Tae-122782	Triticum aestivum	64.71	1.00e-05	44.30
IUUC-Tur-126828	Triticum urartu	64.71	1.00e-05	44.30
IUUC-Tbe-128039	Tupaia belangeri	90.65	6.00e-72	262.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence