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Tag Content
UUCD2 ID IUUC-Cfa-020950
UUCD1 version UUC-CaF-00371
Ensembl Protein ID ENSCAFP00000041077.1
UniProt Accession J9P5Z7; J9P5Z7_CANLF
Genbank Protein ID ENSCAFP00000041077
Protein Name Uncharacterized protein
Genbank Nucleotide ID AAEX03008328
Gene Name UBR2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCAFG00000001697.4 ENSCAFT00000045937.2 ENSCAFP00000041077.1
ENSCAFG00000001697.4 ENSCAFT00000002679.3 ENSCAFP00000002487.3
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/RING 2.30e-09 37.9 1108 1213
E3 activity/N-recognin/N-domain 1.40e-39 134.4 227 302
E3 activity/N-recognin/UBR-box 1.10e-31 109.5 97 167
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/RING
   S: 1    CaiC......................................ledf........kdgplvlpCgHvfhadClqkw............ 29
           C++C                                      +           ++g+++++CgH++ha+C+q++            
   Q: 1108 CILCqeeqevkveskamvlaafvqrstvlsknrskfiqdpekY--DplfmhpdlSCGTHTGSCGHIMHAHCWQRYfdsvqakeqrrq 1192
           8888444444444444443333333333333333333333321..02344444455899**************************** PP
   S: 30   .....pglknssskefrCPlC 45
                + +++++++ef+CPlC
   Q: 1193 qrlrlHTSYDVENGEFLCPLC 1213
           ********************* PP
   

   E3 activity/N-recognin/N-domain
   S: 1    YylvLfNDEkHsyeqviyslqkAleleqkeakkfatiidkeGRravkaGdyavceeakkeilknseklaqipLkVev 77
           Yy++LfNDE+H+yeqviy+lqkA++++qkea++fat++d++GRr+v++Gd+++ce+ak++i++n++++++ pLkV+v
   Q: 227  YYCMLFNDEVHTYEQVIYTLQKAVNCTQKEAIGFATTVDRDGRRSVRYGDFQYCEQAKSVIVRNTSRQTK-PLKVQV 302
           9*********************************************************************.****98 PP
   

   E3 activity/N-recognin/UBR-box
   S: 1    slCgrvfkvgetiyeCrtCsvdetlvlCteCfakvvHkdHeyklkksggggfCdCGdteAwedgskCkkll 71
           +lCgrvfkvge +y+Cr+C+vd+t+vlC+eCf  ++H+dH+y++++sggggfCdCGdteAw++g++C+k++
   Q: 97   HLCGRVFKVGEPTYSCRDCAVDPTCVLCMECFLGSIHRDHRYRMTTSGGGGFCDCGDTEAWKEGPYCQKHE 167
           68******************************************************************996 PP
   
Organism Canis familiaris
Protein Sequence
(Fasta)
MASELEPEVQ AIDRSLLECS AEETAGKWLQ ATDLTREVYQ HLAHYVPKIY CRGPNPFPQK 60
EDMLAQHVLL GPMEWYLCGE DPAFGFPKLE QANKPSHLCG RVFKVGEPTY SCRDCAVDPT 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cfa-020950|E3,RING;E3,N-domain;E3,UBR-box|Canis familiaris
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CTCGGTATCT GTCGGCCTAC CCACAACAGG CTTTGGAAAG TACTTGATGT GTACCACGTG 60
CCAGGCACCG TTCTAGTATC TGCGGATACC AACAGGAACA AAAGGAGCTG GGGGGAGTAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cfa-020950|E3,RING;E3,N-domain;E3,UBR-box|Canis familiaris
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR003769--ClpS_core
IPR014719--Ribosomal_L7/12_C/ClpS-like
IPR011991--WHTH_DNA-bd_dom
IPR013083--Znf_RING/FYVE/PHD
IPR003126--Znf_UBR
PROSITE

PS51157--ZF_UBR
Pfam

PF02617--ClpS
PF02207--zf-UBR
SMART

SM00396--ZnF_UBR1
Gene Ontology

GO:0000785--C:chromatin
GO:0000151--C:ubiquitin ligase complex
GO:0070728--F:leucine binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0071233--P:cellular response to leucine
GO:0006342--P:chromatin silencing
GO:0033522--P:histone H2A ubiquitination
GO:0007141--P:male meiosis I
GO:0032007--P:negative regulation of TOR signaling
GO:0007283--P:spermatogenesis
GO:0006511--P:ubiquitin-dependent protein catabolic process
KEGG cfa:474903
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000949 Aegilops tauschii 27.65 3.00e-22 101.00
IUUC-Aml-001876 Ailuropoda melanoleuca 86.72 0.00e+00 2796.00
IUUC-Atr-002501 Amborella trichopoda 29.02 4.00e-28 121.00
IUUC-Apl-003828 Anas platyrhynchos 87.56 0.00e+00 3071.00
IUUC-Aca-005189 Anolis carolinensis 86.16 0.00e+00 3057.00
IUUC-Aly-005901 Arabidopsis lyrata 32.86 2.00e-26 115.00
IUUC-Ath-007148 Arabidopsis thaliana 31.46 4.00e-25 111.00
IUUC-Ago-007946 Ashbya gossypii 23.62 2.00e-22 102.00
IUUC-Afl-008479 Aspergillus flavus 23.29 5.00e-46 181.00
IUUC-Afu-008929 Aspergillus fumigatus 24.29 2.00e-54 208.00
IUUC-Ani-009334 Aspergillus nidulans 24.18 4.00e-50 194.00
IUUC-Ang-009550 Aspergillus niger 24.02 3.00e-47 185.00
IUUC-Aor-010124 Aspergillus oryzae 23.29 5.00e-46 181.00
IUUC-Ame-011917 Astyanax mexicanus 74.09 0.00e+00 2503.00
IUUC-Bta-012768 Bos taurus 93.68 0.00e+00 3289.00
IUUC-Bdi-014635 Brachypodium distachyon 26.30 5.00e-32 134.00
IUUC-Bol-015669 Brassica oleracea 31.80 6.00e-31 130.00
IUUC-Bra-017776 Brassica rapa 31.80 1.00e-31 132.00
IUUC-Cel-018476 Caenorhabditis elegans 31.43 7.00e-84 306.00
IUUC-Cja-019797 Callithrix jacchus 95.56 0.00e+00 2618.00
IUUC-Cpo-022385 Cavia porcellus 92.54 0.00e+00 3274.00
IUUC-Csa-024082 Chlorocebus sabaeus 96.58 0.00e+00 3369.00
IUUC-Cho-025029 Choloepus hoffmanni 87.39 0.00e+00 2195.00
IUUC-Cin-025148 Ciona intestinalis 36.32 2.00e-138 486.00
IUUC-Csv-026296 Ciona savignyi 31.73 8.00e-21 94.70
IUUC-Cgl-026605 Colletotrichum gloeosporioides 23.84 7.00e-54 207.00
IUUC-Cne-026823 Cryptococcus neoformans 22.17 2.00e-38 155.00
IUUC-Dre-028343 Danio rerio 72.87 0.00e+00 2489.00
IUUC-Dno-030002 Dasypus novemcinctus 93.34 0.00e+00 1977.00
IUUC-Dor-030207 Dipodomys ordii 79.57 0.00e+00 1595.00
IUUC-Dse-031531 Dothistroma septosporum 23.68 3.00e-53 205.00
IUUC-Dme-031910 Drosophila melanogaster 34.99 0.00e+00 680.00
IUUC-Ete-033162 Echinops telfairi 84.56 0.00e+00 1386.00
IUUC-Eca-033454 Equus caballus 95.50 0.00e+00 3334.00
IUUC-Eeu-034783 Erinaceus europaeus 78.32 0.00e+00 1541.00
IUUC-Fca-036588 Felis catus 97.95 0.00e+00 3410.00
IUUC-Fal-036919 Ficedula albicollis 87.78 0.00e+00 3008.00
IUUC-Fox-037984 Fusarium oxysporum 25.15 1.00e-39 159.00
IUUC-Fso-038463 Fusarium solani 24.45 5.00e-44 174.00
IUUC-Gmo-039698 Gadus morhua 69.82 0.00e+00 1615.00
IUUC-Ggr-040070 Gaeumannomyces graminis 23.51 6.00e-45 177.00
IUUC-Gga-041123 Gallus gallus 88.90 0.00e+00 3125.00
IUUC-Gac-042622 Gasterosteus aculeatus 66.04 0.00e+00 2196.00
IUUC-Gma-043622 Glycine max 29.64 5.00e-27 117.00
IUUC-Ggo-045583 Gorilla gorilla 94.79 0.00e+00 3328.00
IUUC-Hsa-046343 Homo sapiens 95.33 0.00e+00 3326.00
IUUC-Hvu-047707 Hordeum vulgare 29.79 1.00e-22 102.00
IUUC-Kpa-049088 Komagataella pastoris 23.17 8.00e-47 183.00
IUUC-Lch-049649 Latimeria chalumnae 75.55 0.00e+00 2612.00
IUUC-Lpe-051516 Leersia perrieri 26.02 8.00e-32 134.00
IUUC-Loc-052818 Lepisosteus oculatus 76.04 0.00e+00 2646.00
IUUC-Lma-053059 Leptosphaeria maculans 23.29 4.00e-48 188.00
IUUC-Laf-054142 Loxodonta africana 93.57 0.00e+00 3293.00
IUUC-Mcc-055677 Macaca mulatta 96.13 0.00e+00 3345.00
IUUC-Meu-056204 Macropus eugenii 68.83 0.00e+00 738.00
IUUC-Mor-057051 Magnaporthe oryzae 23.70 2.00e-50 195.00
IUUC-Mpo-057372 Magnaporthe poae 25.22 8.00e-47 183.00
IUUC-Mtr-058538 Medicago truncatula 30.24 2.00e-29 125.00
IUUC-Mla-058963 Melampsora laricipopulina 25.39 7.00e-57 216.00
IUUC-Mga-059698 Meleagris gallopavo 89.25 0.00e+00 3104.00
IUUC-Mvi-060535 Microbotryum violaceum 25.57 4.00e-52 201.00
IUUC-Mmr-060901 Microcebus murinus 93.50 0.00e+00 3244.00
IUUC-Mdo-062014 Monodelphis domestica 92.14 0.00e+00 3245.00
IUUC-Mmu-063699 Mus musculus 89.91 0.00e+00 3148.00
IUUC-Mac-064773 Musa acuminata 31.10 1.00e-27 120.00
IUUC-Mpu-066153 Mustela putorius furo 98.63 0.00e+00 3439.00
IUUC-Mlu-068151 Myotis lucifugus 94.08 0.00e+00 3281.00
IUUC-Nfi-068403 Neosartorya fischeri 23.67 1.00e-53 206.00
IUUC-Ncr-068864 Neurospora crassa 23.16 1.00e-41 166.00
IUUC-Nle-069529 Nomascus leucogenys 96.35 0.00e+00 3363.00
IUUC-Opr-071107 Ochotona princeps 88.70 0.00e+00 1355.00
IUUC-Ont-072189 Oreochromis niloticus 67.02 0.00e+00 2176.00
IUUC-Oan-072893 Ornithorhynchus anatinus 89.29 0.00e+00 3134.00
IUUC-Ocu-074082 Oryctolagus cuniculus 92.48 0.00e+00 3238.00
IUUC-Obr-076117 Oryza brachyantha 26.12 6.00e-28 120.00
IUUC-Ogl-077571 Oryza glaberrima 30.71 6.00e-23 104.00
IUUC-Ogu-078497 Oryza glumaepatula 23.18 1.00e-14 76.60
IUUC-Olo-081056 Oryza longistaminata 25.61 4.00e-17 85.10
IUUC-Ome-081738 Oryza meridionalis 23.17 8.00e-16 80.50
IUUC-Opu-083202 Oryza punctata 27.09 2.00e-28 122.00
IUUC-Osa-085336 Oryza sativa 29.25 5.00e-23 103.00
IUUC-Ola-087460 Oryzias latipes 65.47 0.00e+00 2157.00
IUUC-Oga-088432 Otolemur garnettii 93.91 0.00e+00 3312.00
IUUC-Oar-090206 Ovis aries 93.71 0.00e+00 3307.00
IUUC-Ptr-091180 Pan troglodytes 95.04 0.00e+00 3326.00
IUUC-Pan-092375 Papio anubis 96.30 0.00e+00 3363.00
IUUC-Psi-093049 Pelodiscus sinensis 88.16 0.00e+00 3068.00
IUUC-Pma-094152 Petromyzon marinus 48.41 0.00e+00 664.00
IUUC-Pno-094877 Phaeosphaeria nodorum 24.78 3.00e-33 138.00
IUUC-Ppa-095715 Physcomitrella patens 28.66 2.00e-23 106.00
IUUC-Pfo-096524 Poecilia formosa 63.65 0.00e+00 2047.00
IUUC-Pab-097989 Pongo abelii 94.47 0.00e+00 3275.00
IUUC-Pca-100207 Procavia capensis 80.89 0.00e+00 1267.00
IUUC-Ppe-101802 Prunus persica 30.04 8.00e-28 120.00
IUUC-Pva-102538 Pteropus vampyrus 94.73 0.00e+00 1234.00
IUUC-Pgr-103372 Puccinia graminis 24.83 2.00e-54 209.00
IUUC-Ptt-103878 Puccinia triticina 24.57 9.00e-51 196.00
IUUC-Rno-105567 Rattus norvegicus 89.86 0.00e+00 3098.00
IUUC-Sce-106272 Saccharomyces cerevisiae 21.13 2.00e-25 112.00
IUUC-Sha-106980 Sarcophilus harrisii 91.49 0.00e+00 3091.00
IUUC-Sja-107980 Schizosaccharomyces japonicus 23.74 1.00e-48 189.00
IUUC-Spo-108183 Schizosaccharomyces pombe 24.88 6.00e-52 200.00
IUUC-Smo-108719 Selaginella moellendorffii 31.90 6.00e-31 130.00
IUUC-Sit-110716 Setaria italica 26.01 3.00e-32 135.00
IUUC-Sly-111286 Solanum lycopersicum 30.12 8.00e-28 120.00
IUUC-Sar-113332 Sorex araneus 87.50 0.00e+00 2205.00
IUUC-Sbi-114577 Sorghum bicolor 29.01 2.00e-31 132.00
IUUC-Sre-115045 Sporisorium reilianum 26.09 3.00e-46 181.00
IUUC-Ssc-115525 Sus scrofa 95.76 0.00e+00 2598.00
IUUC-Tgu-116943 Taeniopygia guttata 88.67 0.00e+00 3110.00
IUUC-Tru-117673 Takifugu rubripes 65.83 0.00e+00 2191.00
IUUC-Tsy-119032 Tarsius syrichta 93.26 0.00e+00 1847.00
IUUC-Tni-119987 Tetraodon nigroviridis 65.32 0.00e+00 2139.00
IUUC-Tca-121077 Theobroma cacao 33.18 1.00e-26 116.00
IUUC-Tre-122137 Trichoderma reesei 24.63 3.00e-59 225.00
IUUC-Tvi-122272 Trichoderma virens 23.12 4.00e-55 211.00
IUUC-Tae-125501 Triticum aestivum 28.93 1.00e-29 125.00
IUUC-Tur-126562 Triticum urartu 28.94 5.00e-29 124.00
IUUC-Tme-127156 Tuber melanosporum 23.98 2.00e-52 202.00
IUUC-Tbe-128103 Tupaia belangeri 88.05 0.00e+00 1254.00
IUUC-Ttr-128253 Tursiops truncatus 89.97 0.00e+00 3106.00
IUUC-Uma-129344 Ustilago maydis 26.60 2.00e-51 199.00
IUUC-Vda-129778 Verticillium dahliae 24.09 2.00e-46 182.00
IUUC-Vpa-130540 Vicugna pacos 91.43 0.00e+00 2983.00
IUUC-Vvi-131290 Vitis vinifera 30.40 7.00e-29 123.00
IUUC-Xtr-132690 Xenopus tropicalis 80.99 0.00e+00 2852.00
IUUC-Xma-133748 Xiphophorus maculatus 64.55 0.00e+00 2019.00
IUUC-Yli-134662 Yarrowia lipolytica 23.84 8.00e-31 130.00
IUUC-Zma-135553 Zea mays 23.98 1.00e-17 87.00
Created Date 25-Jun-2017

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