iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tgu-117167

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01002856

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000011864.1	ENSTGUT00000012359.1	ENSTGUP00000012225.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	6.30e-124	413.5	1120	1578

Active Site

Position(s)	Description	Evidence
1547	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysen..dketlqpnpdsglknp..................... 65
           ++d+k++levef+gEeg++l G+t+ef+al+++e+q++dlg++l++++  d+e++q++   glk+p                     
   Q: 1120 HADRKSVLEVEFLGEEGTGL-GPTLEFYALVAAEFQRTDLGAWLCDDDfpDDESRQVDIGGGLKPPgyyvqrscglftapfpqdsde 1205
           6899****************.******************************************988********************* PP
   S: 66   ..ehlklFeflGrllgkalqdgrlldlplsksfykll.................................................. 100
             + +klF+flG++l+k++qd+rl+dlp+sk+f+kl+                                                  
   Q: 1206 leRITKLFHFLGIFLAKCIQDNRLVDLPISKPFFKLMcmgdiksnmskliyesrgdrdlhctesqseasteeghdslsvgsleedsk 1292
           *************************************99999999999999999999999999999999999999988888887777 PP
   S: 101  ...............lgkklsledleevdpelykslkeikenaes..................................dieelgld 138
                          ++  l++ed+e v+p+++++lkeik++a +                                  +ie+lgl+
   Q: 1293 sefildppkpkppawFNGILTWEDFELVNPHRARFLKEIKDLAIKrrqilsnknlsedekntklqelmlknpsgsgpplSIEDLGLN 1379
           7777777666666666668***********************933444555566777778889999999999*************** PP
   S: 139  ltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeid 225
           ++f++s++++g t+++ LkpgGe++ Vt++N+eeYv+l++++++++gi++q+eafr+Gfn+v+p+e+ls+F++ee+++++cG+   +
   Q: 1380 FQFCPSSKVYGFTAVD-LKPGGEDETVTMDNAEEYVDLMFDFCMHTGIQKQMEAFRDGFNRVFPMEKLSSFSHEEVQMILCGN---Q 1462
           *************999.******************************************************************...6 PP
   S: 226  vedlkket..ky...kggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelkprlfvirk.dasddrlPssnTCfn 306
           ++++++e+  +y   k gyt+dsp++ +F++vl+++ss+erkafLqF+Tg+s+lP+gG+a+l+prl+v+rk da+d+++Ps+nTC++
   Q: 1463 SPSWAAEDiiNYtepKLGYTRDSPGFLRFVRVLCGMSSDERKAFLQFTTGCSTLPPGGLANLHPRLTVVRKvDATDASYPSVNTCVH 1549
           666666665555555************************************************************************ PP
   S: 307  yLkLPeYsskeilkekLlyAieetkgFels 336
           yLkLPeYss+ei++e+Ll+A++e kgF+l+
   Q: 1550 YLKLPEYSSEEIMRERLLAATME-KGFHLN 1578
           ***********************.****96 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

AKQWYDFDRA SFVFVRKLRE GQTFVFRHQH DFDENGIIYW IGTNAKTAYE WVNPAAYGLV 60
VVTSSEGRNL PYGRLEDILS RDSSALNCHT NDDKNAWFAI DLGLWVIPSA YTLRHARGYG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCAAAGCAAT GGTACGACTT TGATAGGGCT TCATTTGTTT TTGTACGAAA ACTACGAGAA 60
GGTCAGACGT TTGTGTTCAG GCATCAACAT GATTTTGATG AAAATGGAAT TATTTACTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR008979--Galactose-bd-like
IPR000569--HECT_dom
IPR010606--Mib_Herc2
IPR012919--SUN_dom

PROSITE

PS50237--HECT
PS51416--MIB_HERC2

Pfam

PF00632--HECT
PF06701--MIB_HERC2
PF07738--Sad1_UNC

SMART

SM00119--HECTc

Gene Ontology

GO:0046872--F:metal ion binding
GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000538	Aegilops tauschii	39.85	6.00e-42	166.00
IUUC-Aml-001987	Ailuropoda melanoleuca	93.60	0.00e+00	2603.00
IUUC-Atr-002821	Amborella trichopoda	40.68	6.00e-49	190.00
IUUC-Apl-003493	Anas platyrhynchos	96.08	0.00e+00	2688.00
IUUC-Aca-004521	Anolis carolinensis	96.86	0.00e+00	1688.00
IUUC-Aly-006493	Arabidopsis lyrata	37.11	8.00e-44	172.00
IUUC-Ath-006679	Arabidopsis thaliana	36.43	7.00e-43	169.00
IUUC-Ago-007875	Ashbya gossypii	40.11	4.00e-32	134.00
IUUC-Ame-011258	Astyanax mexicanus	87.09	0.00e+00	1522.00
IUUC-Bta-012835	Bos taurus	93.86	0.00e+00	2617.00
IUUC-Bdi-014961	Brachypodium distachyon	33.44	5.00e-80	293.00
IUUC-Bol-015440	Brassica oleracea	37.80	4.00e-47	183.00
IUUC-Bra-016648	Brassica rapa	37.46	1.00e-44	175.00
IUUC-Cja-019174	Callithrix jacchus	93.73	0.00e+00	2606.00
IUUC-Cfa-021115	Canis familiaris	93.92	0.00e+00	2614.00
IUUC-Cpo-022382	Cavia porcellus	93.67	0.00e+00	2608.00
IUUC-Cre-022767	Chlamydomonas reinhardtii	40.65	6.00e-42	164.00
IUUC-Csa-023230	Chlorocebus sabaeus	93.86	0.00e+00	2612.00
IUUC-Cho-024711	Choloepus hoffmanni	93.83	0.00e+00	1610.00
IUUC-Cme-027226	Cyanidioschyzon merolae	36.24	4.00e-31	130.00
IUUC-Dre-027435	Danio rerio	86.95	0.00e+00	1531.00
IUUC-Dno-029954	Dasypus novemcinctus	93.79	0.00e+00	2609.00
IUUC-Dor-030734	Dipodomys ordii	96.21	0.00e+00	1256.00
IUUC-Eca-033434	Equus caballus	93.98	0.00e+00	2612.00
IUUC-Fca-035998	Felis catus	91.01	0.00e+00	2492.00
IUUC-Fal-037468	Ficedula albicollis	99.65	0.00e+00	1717.00
IUUC-Fox-038035	Fusarium oxysporum	35.94	8.00e-40	158.00
IUUC-Fso-038320	Fusarium solani	31.19	4.00e-74	273.00
IUUC-Gga-040736	Gallus gallus	99.30	0.00e+00	1708.00
IUUC-Gac-041777	Gasterosteus aculeatus	74.41	0.00e+00	1299.00
IUUC-Ggo-044677	Gorilla gorilla	91.17	0.00e+00	2520.00
IUUC-Hsa-045879	Homo sapiens	93.86	0.00e+00	2612.00
IUUC-Hvu-047700	Hordeum vulgare	39.18	3.00e-43	170.00
IUUC-Itr-048664	Ictidomys tridecemlineatus	93.73	0.00e+00	2608.00
IUUC-Kpa-049098	Komagataella pastoris	37.97	8.00e-35	142.00
IUUC-Lch-050444	Latimeria chalumnae	88.23	0.00e+00	2448.00
IUUC-Lpe-051372	Leersia perrieri	37.46	6.00e-42	166.00
IUUC-Loc-051986	Lepisosteus oculatus	82.91	0.00e+00	2365.00
IUUC-Laf-054230	Loxodonta africana	93.49	0.00e+00	2598.00
IUUC-Mcc-054787	Macaca mulatta	93.86	0.00e+00	2612.00
IUUC-Meu-056502	Macropus eugenii	88.10	0.00e+00	1298.00
IUUC-Mtr-058626	Medicago truncatula	38.79	3.00e-44	174.00
IUUC-Mla-058870	Melampsora laricipopulina	38.50	1.00e-39	159.00
IUUC-Mga-059409	Meleagris gallopavo	92.61	0.00e+00	2146.00
IUUC-Mmr-061667	Microcebus murinus	93.73	0.00e+00	2610.00
IUUC-Mdo-061960	Monodelphis domestica	94.68	0.00e+00	2620.00
IUUC-Mmu-063941	Mus musculus	92.98	0.00e+00	2578.00
IUUC-Mac-065046	Musa acuminata	36.30	3.00e-41	164.00
IUUC-Mpu-065939	Mustela putorius furo	93.79	0.00e+00	2611.00
IUUC-Mlu-068112	Myotis lucifugus	93.54	0.00e+00	2575.00
IUUC-Nle-069001	Nomascus leucogenys	93.73	0.00e+00	2607.00
IUUC-Ont-072101	Oreochromis niloticus	74.85	0.00e+00	2135.00
IUUC-Oan-072814	Ornithorhynchus anatinus	94.17	0.00e+00	2616.00
IUUC-Ocu-074011	Oryctolagus cuniculus	93.67	0.00e+00	2605.00
IUUC-Oba-075380	Oryza barthii	36.95	2.00e-41	164.00
IUUC-Obr-076915	Oryza brachyantha	33.22	5.00e-78	286.00
IUUC-Ogl-077055	Oryza glaberrima	33.06	3.00e-77	284.00
IUUC-Ogu-078892	Oryza glumaepatula	36.95	1.00e-41	165.00
IUUC-Oin-079256	Oryza indica	32.73	3.00e-75	277.00
IUUC-Olo-080343	Oryza longistaminata	32.57	7.00e-75	276.00
IUUC-Ome-081422	Oryza meridionalis	32.40	4.00e-74	273.00
IUUC-Oni-083047	Oryza nivara	38.64	9.00e-43	169.00
IUUC-Opu-083574	Oryza punctata	37.81	9.00e-43	170.00
IUUC-Oru-084439	Oryza rufipogon	36.95	1.00e-41	165.00
IUUC-Osa-085972	Oryza sativa	33.06	5.00e-77	281.00
IUUC-Ola-086412	Oryzias latipes	75.24	0.00e+00	1450.00
IUUC-Olu-087871	Ostreococcus lucimarinus	33.84	7.00e-33	134.00
IUUC-Oar-089668	Ovis aries	93.92	0.00e+00	2611.00
IUUC-Ptr-090517	Pan troglodytes	93.86	0.00e+00	2610.00
IUUC-Pan-091849	Papio anubis	92.91	0.00e+00	2570.00
IUUC-Psi-093390	Pelodiscus sinensis	97.09	0.00e+00	1679.00
IUUC-Ppa-095264	Physcomitrella patens	32.77	2.00e-82	300.00
IUUC-Pab-098176	Pongo abelii	93.86	0.00e+00	2612.00
IUUC-Pca-101123	Procavia capensis	88.66	0.00e+00	2328.00
IUUC-Ppe-101229	Prunus persica	35.23	9.00e-41	162.00
IUUC-Pva-103008	Pteropus vampyrus	87.33	0.00e+00	1578.00
IUUC-Rno-105885	Rattus norvegicus	93.22	0.00e+00	2593.00
IUUC-Sce-106273	Saccharomyces cerevisiae	34.02	1.00e-28	122.00
IUUC-Sha-107048	Sarcophilus harrisii	94.31	0.00e+00	2630.00
IUUC-Sja-107943	Schizosaccharomyces japonicus	39.15	7.00e-36	146.00
IUUC-Spo-108081	Schizosaccharomyces pombe	37.67	1.00e-37	152.00
IUUC-Sit-110717	Setaria italica	32.35	7.00e-78	286.00
IUUC-Sly-111552	Solanum lycopersicum	40.65	4.00e-40	160.00
IUUC-Stu-112896	Solanum tuberosum	39.78	2.00e-47	183.00
IUUC-Sbi-113884	Sorghum bicolor	32.84	2.00e-77	283.00
IUUC-Sre-114993	Sporisorium reilianum	40.57	8.00e-41	163.00
IUUC-Ssc-115963	Sus scrofa	93.16	0.00e+00	2588.00
IUUC-Tru-118626	Takifugu rubripes	75.24	0.00e+00	1504.00
IUUC-Tsy-119504	Tarsius syrichta	95.58	0.00e+00	1652.00
IUUC-Tni-119877	Tetraodon nigroviridis	74.63	0.00e+00	1461.00
IUUC-Tca-121574	Theobroma cacao	34.71	3.00e-36	147.00
IUUC-Tre-122195	Trichoderma reesei	30.42	3.00e-68	254.00
IUUC-Tvi-122650	Trichoderma virens	29.82	2.00e-66	248.00
IUUC-Tae-124494	Triticum aestivum	40.21	2.00e-45	177.00
IUUC-Tur-126730	Triticum urartu	40.27	4.00e-45	176.00
IUUC-Ttr-128394	Tursiops truncatus	93.67	0.00e+00	2620.00
IUUC-Uma-129365	Ustilago maydis	40.09	1.00e-40	162.00
IUUC-Vpa-130280	Vicugna pacos	92.70	0.00e+00	2399.00
IUUC-Vvi-130904	Vitis vinifera	39.85	3.00e-46	180.00
IUUC-Xma-133497	Xiphophorus maculatus	75.81	0.00e+00	2142.00
IUUC-Yli-134481	Yarrowia lipolytica	38.60	7.00e-37	149.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence