• HOME
  • BROWSE
  • SEARCH
  • LINK
  • DOWNLOAD
  • USER GUIDE
  • Protein
  • Gene
  • Annotation
  • Classification
  • Domain Profile
  • Function
  • Protein Sequence
  • Nucleotide Sequence
  • Keyword
  • GO
  • Orthology
  • TOP

Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-064301
UUCD1 version UUC-MuM-00888
Ensembl Protein ID ENSMUSP00000026128.3
UniProt Accession Q9CPX9; Q3UWH1; Q9CTG0; APC11_MOUSE
Genbank Protein ID BAB22663.1; BAB22890.1; BAB22937.1; BAC32348.1; BAE22944.1; AAH23039.1
Protein Name Anaphase-promoting complex subunit 11; Cyclosome subunit 11
Genbank Nucleotide ID AK003244; AK003612; AK003684; AK045408; AK136358; BC023039
Gene Name Anapc11
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000025135.12 ENSMUST00000026128.9 ENSMUSP00000026128.3
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemiRTarBasemicroRNATRANSFAC
RepTarRAID2
Protein-protein Interaction
IIDiRefIndexMentha
Post-translational Modifications (PTMs)
PhosphositePlus
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 activity/RING/RING 48.28 1.00e-17 84.00 IUUC-Cel-018191
E3 adaptor/Cullin RING/APC_C/APC_C 98.81 1.00e-43 171.00 IUUC-Hsa-046268
E3 adaptor/Cullin RING/APC_C/APC_C 44.12 1.00e-19 88.60 IUUC-Sce-106149
E3 activity/RING/RING 53.09 2.00e-21 94.70 IUUC-Spo-108296
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Mus musculus
Functional Description
(View)

Functional Description


     Together with the cullin protein ANAPC2, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex (By similarity).
 Together with the cullin protein ANAPC2, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex (By similarity).
Protein Sequence
(Fasta)
MKVKIKCWNG VATWLWVAND ENCGICRMAF NGCCPDCKVP GDDCPLVWGQ CSHCFHMHCI 60
LKWLNAQQVQ QHCPMCRQEW KFKE 84
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-064301|E3,RING;E3,APC_C|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGCGTCGCGG GCCCGAAGCG AGCGGCGATT GGTCTGGGCG CGCGCGATTC CGCAGAGCGC 60
CTGCGTACGG CTCGCCGCGG TGGCTGGCGC TACTTCGGAG GAGCCCGACG CGGCGCGGTC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-064301|E3,RING;E3,APC_C|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0479--Metal-binding
KW-0498--Mitosis
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0832--Ubl conjugation
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR024991--Apc11
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS50089--ZF_RING_2
Pfam

PF12861--zf-ANAPC11
Gene Ontology

GO:0005680--C:anaphase-promoting complex
GO:0005737--C:cytoplasm
GO:0005730--C:nucleolus
GO:0005654--C:nucleoplasm
GO:0097602--F:cullin family protein binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0008270--F:zinc ion binding
GO:0051301--P:cell division
GO:0007067--P:mitotic nuclear division
GO:0070979--P:protein K11-linked ubiquitination
GO:0016567--P:protein ubiquitination
KEGG mmu:66156
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000514 Aegilops tauschii 39.29 1.00e-06 48.50
IUUC-Aml-002323 Ailuropoda melanoleuca 100.00 1.00e-45 173.00
IUUC-Aly-006393 Arabidopsis lyrata 69.51 1.00e-33 134.00
IUUC-Ath-006698 Arabidopsis thaliana 69.51 1.00e-33 134.00
IUUC-Ago-007824 Ashbya gossypii 43.43 2.00e-19 88.60
IUUC-Acl-008180 Aspergillus clavatus 57.50 5.00e-24 102.00
IUUC-Afl-008622 Aspergillus flavus 57.50 4.00e-24 102.00
IUUC-Afu-008844 Aspergillus fumigatus 56.25 2.00e-23 100.00
IUUC-Ani-009260 Aspergillus nidulans 56.25 1.00e-23 100.00
IUUC-Ang-009794 Aspergillus niger 58.23 1.00e-27 117.00
IUUC-Ame-011274 Astyanax mexicanus 92.86 3.00e-39 152.00
IUUC-Bgr-012017 Blumeria graminis 50.63 1.00e-18 84.30
IUUC-Bta-012644 Bos taurus 98.81 2.00e-45 172.00
IUUC-Bci-013779 Botrytis cinerea 52.94 9.00e-24 101.00
IUUC-Bdi-014975 Brachypodium distachyon 68.67 2.00e-32 129.00
IUUC-Bol-016184 Brassica oleracea 71.43 2.00e-32 129.00
IUUC-Bra-016983 Brassica rapa 66.67 7.00e-34 135.00
IUUC-Cel-018191 Caenorhabditis elegans 48.28 3.00e-18 84.00
IUUC-Cja-019909 Callithrix jacchus 98.81 4.00e-45 171.00
IUUC-Cfa-020306 Canis familiaris 100.00 1.00e-45 173.00
IUUC-Cpo-021773 Cavia porcellus 100.00 1.00e-45 173.00
IUUC-Cre-022961 Chlamydomonas reinhardtii 54.76 3.00e-24 102.00
IUUC-Csa-024274 Chlorocebus sabaeus 98.81 4.00e-45 171.00
IUUC-Cgl-026398 Colletotrichum gloeosporioides 53.57 2.00e-23 99.80
IUUC-Cne-027036 Cryptococcus neoformans 45.19 2.00e-22 97.40
IUUC-Cme-027263 Cyanidioschyzon merolae 55.95 1.00e-26 110.00
IUUC-Dre-027617 Danio rerio 92.86 2.00e-39 153.00
IUUC-Dse-031304 Dothistroma septosporum 58.02 8.00e-24 101.00
IUUC-Dme-031897 Drosophila melanogaster 73.49 1.00e-34 137.00
IUUC-Fca-036297 Felis catus 100.00 2.00e-46 176.00
IUUC-Fal-037228 Ficedula albicollis 89.29 4.00e-43 165.00
IUUC-Fox-037929 Fusarium oxysporum 60.34 9.00e-16 74.30
IUUC-Fso-038194 Fusarium solani 56.96 3.00e-22 96.30
IUUC-Gmo-039638 Gadus morhua 95.74 2.00e-19 86.30
IUUC-Gga-040897 Gallus gallus 90.48 5.00e-43 164.00
IUUC-Gac-041644 Gasterosteus aculeatus 95.74 2.00e-19 86.30
IUUC-Gma-043111 Glycine max 68.29 2.00e-33 133.00
IUUC-Hsa-046268 Homo sapiens 98.81 4.00e-45 171.00
IUUC-Hvu-047356 Hordeum vulgare 67.47 8.00e-32 127.00
IUUC-Itr-048453 Ictidomys tridecemlineatus 100.00 1.00e-45 173.00
IUUC-Kpa-049388 Komagataella pastoris 42.20 8.00e-19 85.90
IUUC-Lch-049838 Latimeria chalumnae 91.67 8.00e-43 164.00
IUUC-Lpe-050878 Leersia perrieri 73.02 1.00e-25 107.00
IUUC-Lma-053166 Leptosphaeria maculans 53.57 5.00e-24 102.00
IUUC-Laf-054221 Loxodonta africana 100.00 1.00e-45 173.00
IUUC-Mor-056930 Magnaporthe oryzae 56.47 1.00e-24 104.00
IUUC-Mtr-058104 Medicago truncatula 72.37 1.00e-32 130.00
IUUC-Mla-059079 Melampsora laricipopulina 47.66 2.00e-24 103.00
IUUC-Mvi-060446 Microbotryum violaceum 67.24 9.00e-23 99.40
IUUC-Mac-064936 Musa acuminata 72.29 2.00e-34 137.00
IUUC-Mpu-066041 Mustela putorius furo 100.00 1.00e-45 173.00
IUUC-Mlu-067360 Myotis lucifugus 98.81 2.00e-45 172.00
IUUC-Ncr-068931 Neurospora crassa 56.10 8.00e-24 101.00
IUUC-Ont-072502 Oreochromis niloticus 93.98 2.00e-39 152.00
IUUC-Ocu-074751 Oryctolagus cuniculus 89.29 1.00e-40 156.00
IUUC-Oba-075026 Oryza barthii 71.08 4.00e-33 132.00
IUUC-Obr-076888 Oryza brachyantha 69.88 7.00e-33 132.00
IUUC-Ogl-077846 Oryza glaberrima 71.08 4.00e-33 132.00
IUUC-Ogu-078433 Oryza glumaepatula 69.88 1.00e-33 135.00
IUUC-Oin-079264 Oryza indica 71.08 4.00e-33 132.00
IUUC-Ome-081297 Oryza meridionalis 74.60 2.00e-26 111.00
IUUC-Oni-082739 Oryza nivara 71.08 1.00e-33 135.00
IUUC-Opu-083502 Oryza punctata 74.60 1.00e-25 107.00
IUUC-Oru-084838 Oryza rufipogon 71.08 1.00e-33 134.00
IUUC-Osa-085826 Oryza sativa 71.08 4.00e-33 132.00
IUUC-Ola-087572 Oryzias latipes 94.05 2.00e-39 153.00
IUUC-Olu-087765 Ostreococcus lucimarinus 52.94 9.00e-24 100.00
IUUC-Oga-088853 Otolemur garnettii 97.62 1.00e-44 170.00
IUUC-Oar-089687 Ovis aries 100.00 1.00e-45 173.00
IUUC-Ptr-091674 Pan troglodytes 98.81 4.00e-45 171.00
IUUC-Psi-093124 Pelodiscus sinensis 96.43 2.00e-44 169.00
IUUC-Pno-094852 Phaeosphaeria nodorum 53.57 5.00e-24 102.00
IUUC-Ppa-095866 Physcomitrella patens 67.11 4.00e-30 122.00
IUUC-Pfo-096410 Poecilia formosa 91.67 9.00e-39 150.00
IUUC-Pop-099204 Populus trichocarpa 72.73 3.00e-33 132.00
IUUC-Ppe-101903 Prunus persica 69.88 5.00e-33 131.00
IUUC-Pte-104160 Pyrenophora teres 52.38 5.00e-23 99.00
IUUC-Rno-104979 Rattus norvegicus 100.00 1.00e-45 173.00
IUUC-Sce-106149 Saccharomyces cerevisiae 44.12 1.00e-19 88.60
IUUC-Sja-107930 Schizosaccharomyces japonicus 52.94 4.00e-24 102.00
IUUC-Spo-108296 Schizosaccharomyces pombe 53.09 6.00e-22 94.70
IUUC-Ssl-108464 Sclerotinia sclerotiorum 47.50 4.00e-15 72.00
IUUC-Smo-109289 Selaginella moellendorffii 67.11 2.00e-30 123.00
IUUC-Sit-109777 Setaria italica 68.67 3.00e-32 129.00
IUUC-Sly-111381 Solanum lycopersicum 74.36 4.00e-14 68.90
IUUC-Stu-112287 Solanum tuberosum 71.43 4.00e-33 132.00
IUUC-Sbi-113803 Sorghum bicolor 68.67 2.00e-32 129.00
IUUC-Sre-115018 Sporisorium reilianum 55.81 4.00e-22 95.90
IUUC-Ssc-116403 Sus scrofa 93.98 2.00e-42 162.00
IUUC-Tgu-117375 Taeniopygia guttata 89.29 4.00e-43 165.00
IUUC-Tru-118064 Takifugu rubripes 91.25 2.00e-36 142.00
IUUC-Tni-120387 Tetraodon nigroviridis 91.67 5.00e-39 151.00
IUUC-Tca-121186 Theobroma cacao 73.21 7.00e-23 98.20
IUUC-Tre-122153 Trichoderma reesei 56.25 1.00e-23 100.00
IUUC-Tvi-122412 Trichoderma virens 52.94 1.00e-23 100.00
IUUC-Tae-125184 Triticum aestivum 68.67 3.00e-32 129.00
IUUC-Tur-126516 Triticum urartu 67.47 2.00e-32 129.00
IUUC-Tme-127121 Tuber melanosporum 53.01 2.00e-24 103.00
IUUC-Uma-129529 Ustilago maydis 57.32 2.00e-21 93.60
IUUC-Vvi-131191 Vitis vinifera 72.37 5.00e-33 132.00
IUUC-Xma-133275 Xiphophorus maculatus 90.48 3.00e-38 149.00
IUUC-Yli-134369 Yarrowia lipolytica 60.98 5.00e-26 108.00
IUUC-Zma-134869 Zea mays 68.67 5.00e-32 128.00
Created Date 25-Jun-2017

https://dev.news.makassarkota.go.id/public/pgsoft-demo/ https://jdih.sumbawabaratkab.go.id/lato/pg-soft-demo/ https://dev.news.makassarkota.go.id/public/slot-gacor/ http://pbb.tanahbumbukab.go.id/-/slot-gacor/ slot gacor https://siakad.unipra.ac.id/sass/slot-gacor-x500/ http://kpm.dinus.ac.id/assets/images/berita/slot/
Copyright © 2004-2017.The CUCKOO Workgroup. All Rights Reserved