iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Fca-036594

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02138943

Gene Name

UBE3B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000008951.3	ENSFCAT00000008953.3	ENSFCAP00000008297.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	9.40e-112	373.7	703	1068

Active Site

Position(s)	Description	Evidence
1036	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalq 83
           ++++k +++v+fv+     E+g+d++Gv++efl++++k++++p l+lf+++++d++ l+p+p+s++++ ++l+lFef+G++lgka++
   Q: 703  QHAMKGVIRVKFVNdlgvdEAGIDQDGVFKEFLEEIIKRVFDPALNLFKTTSGDER-LYPSPTSYIHE-NYLQLFEFVGKMLGKAVY 787
           7899********************************************99987665.59*******76.****************** PP
   S: 84   dgrlldlplsksfyklllgk.....klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipV 165
           +g ++d+p++++f+++llg+       s+++l+++d+e+yk+l++ik++ e di +lgl+l++  +e+++g+  ++eL pgG+++pV
   Q: 788  EGIVVDVPFASFFLSQLLGHhhsvfYSSVDELPSLDSEFYKNLTSIKRY-EGDIADLGLTLSY--DEDVMGQLVCHELTPGGKTTPV 871
           ********************777777999********************.7899998777776..5999****************** PP
   S: 166  tneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwe 251
           tn+Nk +Y++l++++r++++ik+q++a+ +Gf+++i++e++++F++ el+ li+G+ +eid+edlkk+t y gg++ ++++i+w+w+
   Q: 872  TNANKISYIHLMAHFRMHTQIKNQTAALISGFRSIIKPEWIRMFSTPELQRLISGDnAEIDLEDLKKHTVYYGGFHGSHRVIIWLWD 958
           ********************************************************9****************************** PP
   S: 252  vl.eefsseerkafLqFvTgssrlPlgGfaelk........................prlfvirkdasddrlPssnTCfnyLkLPeY 313
           +l ++f+ +er++fL+FvT++sr Pl Gfa+lk                        + +f+irk +   rlP+s+TCfn+LkLP+Y
   Q: 959  ILaSDFTPDERAMFLKFVTSCSRPPLLGFAYLKppfsircvevsddqdtgdtlgsvlRGFFTIRKREPGGRLPTSSTCFNLLKLPNY 1045
           **99*************************************************************8888****************** PP
   S: 314  sskeilkekLlyAieetkgFels 336
           s k++l+ekL+yA+++++gFels
   Q: 1046 SRKSVLREKLRYAVSMNTGFELS 1068
           ********************985 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MFTVSQTSRA WFIDRARQAR EERLVQKERE RAAVEIQAHV RSFLCRRRLQ REIRREIDEF 60
FKADDVESSK RSALCIFKIA RKLLFLFRIK EDNERFEKLC RCILSSMDAE NEPKVWYVSL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTCACCG TTTCTCAGAC CTCGAGAGCA TGGTTCATCG ATAGAGCCCG TCAGGCTCGG 60
GAGGAAAGGC TGGTGCAGAA GGAGCGGGAG CGGGCGGCCG TCGAGATCCA GGCCCATGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS
IPR027401--Myosin-like_IQ_dom

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT
PF00612--IQ

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

KEGG

fca:101085926

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000128	Aegilops tauschii	39.08	1.00e-104	374.00
IUUC-Aml-002107	Ailuropoda melanoleuca	96.72	0.00e+00	2083.00
IUUC-Atr-003017	Amborella trichopoda	38.12	4.00e-109	389.00
IUUC-Apl-003328	Anas platyrhynchos	89.06	0.00e+00	1843.00
IUUC-Aly-005794	Arabidopsis lyrata	38.21	2.00e-107	384.00
IUUC-Ath-007269	Arabidopsis thaliana	38.93	4.00e-111	396.00
IUUC-Bta-013547	Bos taurus	95.51	0.00e+00	2096.00
IUUC-Bdi-014502	Brachypodium distachyon	39.15	7.00e-110	392.00
IUUC-Bol-015093	Brassica oleracea	39.64	5.00e-112	399.00
IUUC-Bra-016722	Brassica rapa	39.64	5.00e-113	402.00
IUUC-Cel-018447	Caenorhabditis elegans	38.33	0.00e+00	682.00
IUUC-Cja-019855	Callithrix jacchus	95.69	0.00e+00	2055.00
IUUC-Cfa-020066	Canis familiaris	96.23	0.00e+00	2060.00
IUUC-Cpo-021504	Cavia porcellus	94.10	0.00e+00	2047.00
IUUC-Csa-023579	Chlorocebus sabaeus	95.51	0.00e+00	2052.00
IUUC-Cho-024430	Choloepus hoffmanni	85.68	0.00e+00	1541.00
IUUC-Cin-025750	Ciona intestinalis	46.98	0.00e+00	959.00
IUUC-Csv-026016	Ciona savignyi	47.57	0.00e+00	1001.00
IUUC-Dre-028271	Danio rerio	80.65	0.00e+00	1734.00
IUUC-Dno-029054	Dasypus novemcinctus	95.60	0.00e+00	2056.00
IUUC-Dor-030938	Dipodomys ordii	87.36	0.00e+00	1840.00
IUUC-Dme-031602	Drosophila melanogaster	48.24	0.00e+00	959.00
IUUC-Ete-033041	Echinops telfairi	76.28	0.00e+00	1348.00
IUUC-Eca-034411	Equus caballus	95.97	0.00e+00	2058.00
IUUC-Eeu-035201	Erinaceus europaeus	84.05	0.00e+00	804.00
IUUC-Fal-037317	Ficedula albicollis	84.13	0.00e+00	1839.00
IUUC-Gmo-039412	Gadus morhua	76.90	0.00e+00	1701.00
IUUC-Gga-040149	Gallus gallus	87.76	0.00e+00	1862.00
IUUC-Gac-042088	Gasterosteus aculeatus	79.46	0.00e+00	1785.00
IUUC-Gma-043839	Glycine max	39.43	6.00e-110	392.00
IUUC-Ggo-045279	Gorilla gorilla	95.51	0.00e+00	2053.00
IUUC-Hsa-045660	Homo sapiens	95.22	0.00e+00	2047.00
IUUC-Hvu-047102	Hordeum vulgare	35.66	1.00e-104	374.00
IUUC-Itr-048021	Ictidomys tridecemlineatus	93.62	0.00e+00	1031.00
IUUC-Lch-050664	Latimeria chalumnae	81.61	0.00e+00	1800.00
IUUC-Lpe-050755	Leersia perrieri	36.57	4.00e-98	352.00
IUUC-Loc-052791	Lepisosteus oculatus	82.03	0.00e+00	1761.00
IUUC-Laf-053902	Loxodonta africana	95.60	0.00e+00	2058.00
IUUC-Mcc-054730	Macaca mulatta	95.41	0.00e+00	2051.00
IUUC-Meu-056527	Macropus eugenii	78.92	0.00e+00	1650.00
IUUC-Mtr-057671	Medicago truncatula	39.25	5.00e-110	392.00
IUUC-Mga-059260	Meleagris gallopavo	87.41	0.00e+00	1862.00
IUUC-Mmr-060804	Microcebus murinus	93.73	0.00e+00	1984.00
IUUC-Mdo-062575	Monodelphis domestica	83.01	0.00e+00	1763.00
IUUC-Mmu-063636	Mus musculus	90.84	0.00e+00	1908.00
IUUC-Mac-064989	Musa acuminata	38.83	1.00e-105	378.00
IUUC-Mpu-066677	Mustela putorius furo	96.72	0.00e+00	1955.00
IUUC-Mlu-067952	Myotis lucifugus	94.86	0.00e+00	1986.00
IUUC-Nle-069153	Nomascus leucogenys	95.22	0.00e+00	2049.00
IUUC-Opr-070554	Ochotona princeps	93.56	0.00e+00	1864.00
IUUC-Ont-071372	Oreochromis niloticus	80.64	0.00e+00	1764.00
IUUC-Oan-073327	Ornithorhynchus anatinus	70.83	0.00e+00	733.00
IUUC-Ocu-074183	Oryctolagus cuniculus	94.11	0.00e+00	2002.00
IUUC-Oba-075213	Oryza barthii	38.68	3.00e-106	380.00
IUUC-Obr-076320	Oryza brachyantha	34.95	8.00e-110	391.00
IUUC-Ogl-077093	Oryza glaberrima	38.85	6.00e-109	389.00
IUUC-Ogu-078947	Oryza glumaepatula	36.97	7.00e-109	388.00
IUUC-Oin-080058	Oryza indica	38.85	8.00e-109	388.00
IUUC-Olo-080742	Oryza longistaminata	34.94	3.00e-108	387.00
IUUC-Ome-081741	Oryza meridionalis	34.62	3.00e-102	367.00
IUUC-Oni-082385	Oryza nivara	36.97	7.00e-109	388.00
IUUC-Opu-083529	Oryza punctata	35.56	2.00e-108	387.00
IUUC-Oru-085128	Oryza rufipogon	37.11	4.00e-95	342.00
IUUC-Osa-085557	Oryza sativa	38.85	2.00e-108	386.00
IUUC-Ola-087337	Oryzias latipes	79.89	0.00e+00	1702.00
IUUC-Oga-088342	Otolemur garnettii	94.57	0.00e+00	1969.00
IUUC-Oar-090234	Ovis aries	95.27	0.00e+00	2066.00
IUUC-Ptr-091661	Pan troglodytes	95.51	0.00e+00	2053.00
IUUC-Pan-092728	Papio anubis	95.23	0.00e+00	2047.00
IUUC-Psi-093251	Pelodiscus sinensis	87.19	0.00e+00	1726.00
IUUC-Pma-094195	Petromyzon marinus	70.11	0.00e+00	1445.00
IUUC-Ppa-095544	Physcomitrella patens	37.54	1.00e-108	388.00
IUUC-Pfo-097472	Poecilia formosa	80.07	0.00e+00	1768.00
IUUC-Pab-098570	Pongo abelii	95.32	0.00e+00	2050.00
IUUC-Pca-100110	Procavia capensis	83.71	0.00e+00	1743.00
IUUC-Ppe-101281	Prunus persica	39.18	4.00e-107	382.00
IUUC-Pva-102887	Pteropus vampyrus	90.65	0.00e+00	1916.00
IUUC-Rno-106028	Rattus norvegicus	88.05	0.00e+00	1810.00
IUUC-Sha-107331	Sarcophilus harrisii	84.33	0.00e+00	1787.00
IUUC-Smo-109488	Selaginella moellendorffii	37.32	7.00e-106	379.00
IUUC-Sit-109811	Setaria italica	35.75	8.00e-111	395.00
IUUC-Sly-111362	Solanum lycopersicum	35.66	7.00e-102	365.00
IUUC-Sar-113287	Sorex araneus	85.25	0.00e+00	712.00
IUUC-Sbi-114433	Sorghum bicolor	35.38	3.00e-110	393.00
IUUC-Ssc-116103	Sus scrofa	96.07	0.00e+00	2055.00
IUUC-Tgu-117275	Taeniopygia guttata	87.29	0.00e+00	1849.00
IUUC-Tru-118681	Takifugu rubripes	79.14	0.00e+00	1778.00
IUUC-Tsy-118985	Tarsius syrichta	91.38	0.00e+00	1009.00
IUUC-Tni-120850	Tetraodon nigroviridis	90.23	0.00e+00	768.00
IUUC-Tca-121770	Theobroma cacao	38.83	8.00e-110	392.00
IUUC-Tae-125466	Triticum aestivum	36.66	2.00e-108	387.00
IUUC-Tur-126086	Triticum urartu	39.08	4.00e-104	373.00
IUUC-Tbe-127461	Tupaia belangeri	90.64	0.00e+00	1882.00
IUUC-Ttr-129269	Tursiops truncatus	95.32	0.00e+00	2036.00
IUUC-Vpa-130523	Vicugna pacos	77.96	8.00e-128	451.00
IUUC-Vvi-131524	Vitis vinifera	38.68	5.00e-108	385.00
IUUC-Xtr-132146	Xenopus tropicalis	83.02	0.00e+00	1812.00
IUUC-Xma-133526	Xiphophorus maculatus	79.98	0.00e+00	1768.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence