iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Nfi-068280

Ensembl Protein ID

CADNFIAP00000947

UniProt Accession

A1D4K3; A1D4K3_NEOFI

Genbank Protein ID

EAW23346.1

Protein Name

Ubiquitin ligase, putative

Genbank Nucleotide ID

DS027688

Gene Name

NFIA_020540

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADNFIAG00000986	CADNFIAT00000986	CADNFIAP00000947

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.70e-87	293.0	849	1225

Active Site

Position(s)	Description	Evidence
1193	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 5    lkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknp....................ehlkl 70
           lk+ ++++f +     E+g+d gGvt+efl+ +++e +++  +  l++end++ l+pnp++  +                      + l+ 
   Q: 849  LKEPIQISFIDkfntvEAGIDGGGVTKEFLTSVTNEAFKSGSEPKLFEENDQHLLYPNPAAVEQRRevlrqlgfvenspewnekvrDLLRR 939
           6778889999999999***********************9976666799************98766************************* PP
   S: 71   FeflGrllgkalqdgrlldlplsksfyklllgk............klsledleevdpelykslkeikenaesdieelgldltfsvseei.. 147
           +eflGr++gk+l++g l+d++++++f+ +   +            + +l+dl+++d+ ly+ l ++k++   d+e+ +l++t++  ++i  
   Q: 940  YEFLGRIIGKCLYEGILVDVNFASFFLLKWALTggagsaqretayRANLNDLKDLDQGLYQGLLQLKNY-TGDVEDFALNFTVT--DTIpl 1027
           **************************988744445666767777789********************99.67999987777776..44445 PP
   S: 148  ...lgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketk 234
                 t +++Lk++G++ipVtn+N+  Y++ ++ yrl+ + + q++af +G+  +i++++ls+F+++el++l++Ge  +idv dl+++t 
   Q: 1028 pngGTRTVTRDLKSNGSDIPVTNQNRLVYISYIARYRLQVQPALQTNAFLQGLGHIIQPSWLSMFNQSELQTLVSGEsGDIDVADLRRNTL 1118
           66566666777*******************************************************************************9 PP
   S: 235  y.....kggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelkprlfvirk.dasddrlPssnTCfnyLkLPeYsskeil 319
           y      g+ +e++p+++ Fw+v+ee+s+eer++ L+FvT+++r+Pl Gf  l+pr f ir+ ++++drlPs +TC+n+LkLP+Y++ ++l
   Q: 1119 YggvytIGDDKEEHPTVKLFWQVMEEMSNEERQKVLRFVTSTPRAPLLGFSHLNPR-FSIRDsSEDQDRLPSTSTCVNLLKLPRYTNAKVL 1208
           866556455579******************************************99.8999946666************************ PP
   S: 320  kekLlyAieetkgFels 336
           +ekLlyAi++++gF+ls
   Q: 1209 REKLLYAINSGAGFDLS 1225
           **************985 PP

Organism

Neosartorya fischeri

Protein Sequence
(Fasta)

MFLSFTGNSR RPRQVNLGGR NTNPFAAYPS GRHPPQGPSA QNTLAIAQQE RLLRQQERER 60
LGATRKIQRI WRGYRSRKLA HNTWRTEWDT AERQRTGSPL PFEDKTRTPD AFLQPSLRYG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTCCTGT CTTTCACCGG AAACTCTCGC CGTCCGCGGC AGGTCAATCT CGGAGGTCGT 60
AATACGAATC CTTTCGCTGC CTACCCTTCC GGGCGACATC CTCCTCAGGG ACCGAGCGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

KEGG

nfi:NFIA_020540

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000128	Aegilops tauschii	34.83	3.00e-81	295.00
IUUC-Aml-001355	Ailuropoda melanoleuca	36.19	1.00e-86	313.00
IUUC-Atr-003017	Amborella trichopoda	37.71	2.00e-80	292.00
IUUC-Apl-003731	Anas platyrhynchos	37.07	1.00e-89	322.00
IUUC-Aca-005248	Anolis carolinensis	36.72	1.00e-88	319.00
IUUC-Aly-005768	Arabidopsis lyrata	37.15	2.00e-81	296.00
IUUC-Ath-007269	Arabidopsis thaliana	39.32	9.00e-83	300.00
IUUC-Ago-007748	Ashbya gossypii	39.66	9.00e-83	300.00
IUUC-Acl-008158	Aspergillus clavatus	88.66	0.00e+00	2010.00
IUUC-Afl-008398	Aspergillus flavus	80.21	0.00e+00	1788.00
IUUC-Afu-008937	Aspergillus fumigatus	97.47	0.00e+00	2248.00
IUUC-Ani-009252	Aspergillus nidulans	75.88	0.00e+00	1767.00
IUUC-Ang-009773	Aspergillus niger	82.10	0.00e+00	1872.00
IUUC-Aor-009940	Aspergillus oryzae	80.29	0.00e+00	1790.00
IUUC-Ate-010395	Aspergillus terreus	80.63	0.00e+00	1754.00
IUUC-Ame-010769	Astyanax mexicanus	36.48	7.00e-61	227.00
IUUC-Bgr-012269	Blumeria graminis	62.69	9.00e-174	601.00
IUUC-Bta-012841	Bos taurus	37.07	3.00e-89	321.00
IUUC-Bci-013743	Botrytis cinerea	45.58	0.00e+00	948.00
IUUC-Bdi-014502	Brachypodium distachyon	39.30	5.00e-83	301.00
IUUC-Bol-015093	Brassica oleracea	38.90	4.00e-82	298.00
IUUC-Bra-016722	Brassica rapa	39.11	7.00e-83	300.00
IUUC-Cel-018447	Caenorhabditis elegans	32.86	4.00e-60	224.00
IUUC-Cja-019743	Callithrix jacchus	36.10	9.00e-86	310.00
IUUC-Cfa-021031	Canis familiaris	36.36	2.00e-87	315.00
IUUC-Cpo-022401	Cavia porcellus	35.28	9.00e-88	317.00
IUUC-Cre-022725	Chlamydomonas reinhardtii	36.94	2.00e-69	254.00
IUUC-Csa-024107	Chlorocebus sabaeus	36.02	3.00e-86	311.00
IUUC-Cho-024750	Choloepus hoffmanni	42.74	5.00e-77	281.00
IUUC-Cin-025750	Ciona intestinalis	31.05	8.00e-62	230.00
IUUC-Csv-026016	Ciona savignyi	33.33	4.00e-69	254.00
IUUC-Cgl-026559	Colletotrichum gloeosporioides	42.66	0.00e+00	859.00
IUUC-Cne-026841	Cryptococcus neoformans	37.44	3.00e-90	325.00
IUUC-Cme-027265	Cyanidioschyzon merolae	40.43	4.00e-81	294.00
IUUC-Dre-028196	Danio rerio	37.93	6.00e-92	330.00
IUUC-Dno-029024	Dasypus novemcinctus	36.54	2.00e-88	318.00
IUUC-Dor-030938	Dipodomys ordii	34.51	2.00e-66	246.00
IUUC-Dse-031416	Dothistroma septosporum	44.07	0.00e+00	847.00
IUUC-Dme-031946	Drosophila melanogaster	37.32	3.00e-79	288.00
IUUC-Ete-033041	Echinops telfairi	29.94	1.00e-43	170.00
IUUC-Eca-033828	Equus caballus	36.55	7.00e-88	317.00
IUUC-Eeu-035201	Erinaceus europaeus	30.40	2.00e-43	169.00
IUUC-Fca-035907	Felis catus	36.08	3.00e-87	315.00
IUUC-Fal-037389	Ficedula albicollis	37.07	4.00e-89	321.00
IUUC-Fox-037788	Fusarium oxysporum	44.17	0.00e+00	707.00
IUUC-Fso-038088	Fusarium solani	40.32	0.00e+00	727.00
IUUC-Gmo-039412	Gadus morhua	32.52	5.00e-68	251.00
IUUC-Ggr-039941	Gaeumannomyces graminis	40.61	0.00e+00	758.00
IUUC-Gga-040310	Gallus gallus	36.90	2.00e-88	319.00
IUUC-Gac-042088	Gasterosteus aculeatus	30.13	3.00e-71	261.00
IUUC-Gma-042728	Glycine max	39.03	2.00e-81	296.00
IUUC-Ggo-045031	Gorilla gorilla	36.19	1.00e-86	313.00
IUUC-Hsa-045880	Homo sapiens	36.19	9.00e-87	313.00
IUUC-Hvu-047102	Hordeum vulgare	34.66	2.00e-80	292.00
IUUC-Itr-048372	Ictidomys tridecemlineatus	34.51	7.00e-68	249.00
IUUC-Kpa-049307	Komagataella pastoris	35.08	2.00e-82	299.00
IUUC-Lch-050664	Latimeria chalumnae	30.18	3.00e-70	258.00
IUUC-Lpe-050755	Leersia perrieri	39.41	1.00e-81	296.00
IUUC-Loc-052218	Lepisosteus oculatus	37.05	3.00e-89	322.00
IUUC-Lma-053096	Leptosphaeria maculans	50.27	0.00e+00	1023.00
IUUC-Laf-053902	Loxodonta africana	31.98	1.00e-68	253.00
IUUC-Mcc-055127	Macaca mulatta	36.19	9.00e-87	313.00
IUUC-Meu-056527	Macropus eugenii	37.58	5.00e-56	211.00
IUUC-Mor-057021	Magnaporthe oryzae	40.89	0.00e+00	771.00
IUUC-Mpo-057570	Magnaporthe poae	46.51	0.00e+00	709.00
IUUC-Mtr-057671	Medicago truncatula	38.70	1.00e-82	300.00
IUUC-Mla-059124	Melampsora laricipopulina	41.85	5.00e-98	349.00
IUUC-Mga-059581	Meleagris gallopavo	36.90	1.00e-88	319.00
IUUC-Mvi-060445	Microbotryum violaceum	37.93	8.00e-118	416.00
IUUC-Mmr-061360	Microcebus murinus	36.19	3.00e-87	315.00
IUUC-Mdo-062194	Monodelphis domestica	36.72	2.00e-89	322.00
IUUC-Mmu-064189	Mus musculus	36.19	1.00e-86	313.00
IUUC-Mac-065275	Musa acuminata	37.61	1.00e-80	293.00
IUUC-Mpu-066439	Mustela putorius furo	36.54	6.00e-87	314.00
IUUC-Mlu-068228	Myotis lucifugus	36.38	2.00e-87	316.00
IUUC-Ncr-068869	Neurospora crassa	40.80	0.00e+00	745.00
IUUC-Nle-069687	Nomascus leucogenys	35.74	2.00e-86	312.00
IUUC-Opr-070554	Ochotona princeps	32.18	1.00e-68	253.00
IUUC-Ont-071836	Oreochromis niloticus	37.59	1.00e-89	323.00
IUUC-Oan-072800	Ornithorhynchus anatinus	36.72	1.00e-88	319.00
IUUC-Ocu-074587	Oryctolagus cuniculus	36.71	3.00e-88	318.00
IUUC-Oba-075213	Oryza barthii	38.65	2.00e-83	302.00
IUUC-Obr-076320	Oryza brachyantha	38.85	1.00e-83	303.00
IUUC-Ogl-077093	Oryza glaberrima	38.90	4.00e-84	304.00
IUUC-Ogu-078947	Oryza glumaepatula	37.76	6.00e-82	297.00
IUUC-Oin-080058	Oryza indica	38.85	9.00e-84	303.00
IUUC-Olo-080742	Oryza longistaminata	38.85	4.00e-84	305.00
IUUC-Ome-081741	Oryza meridionalis	37.63	2.00e-78	285.00
IUUC-Oni-082385	Oryza nivara	37.76	7.00e-82	297.00
IUUC-Opu-083529	Oryza punctata	39.06	2.00e-84	306.00
IUUC-Oru-085128	Oryza rufipogon	36.86	3.00e-74	271.00
IUUC-Osa-085557	Oryza sativa	38.85	2.00e-83	302.00
IUUC-Ola-087209	Oryzias latipes	37.41	7.00e-90	323.00
IUUC-Olu-087902	Ostreococcus lucimarinus	36.73	2.00e-67	247.00
IUUC-Oga-088776	Otolemur garnettii	36.36	5.00e-87	314.00
IUUC-Oar-089441	Ovis aries	37.07	3.00e-89	322.00
IUUC-Ptr-091273	Pan troglodytes	36.19	8.00e-87	313.00
IUUC-Pan-091981	Papio anubis	36.19	9.00e-87	313.00
IUUC-Psi-093251	Pelodiscus sinensis	30.86	3.00e-56	211.00
IUUC-Pma-094738	Petromyzon marinus	36.05	1.00e-83	303.00
IUUC-Pno-095132	Phaeosphaeria nodorum	52.17	0.00e+00	809.00
IUUC-Ppa-095544	Physcomitrella patens	39.42	9.00e-85	307.00
IUUC-Pfo-097511	Poecilia formosa	37.76	2.00e-89	322.00
IUUC-Pab-098634	Pongo abelii	33.96	5.00e-75	274.00
IUUC-Pop-099574	Populus trichocarpa	36.02	3.00e-71	261.00
IUUC-Pca-100987	Procavia capensis	42.18	3.00e-80	291.00
IUUC-Ppe-101281	Prunus persica	34.71	2.00e-82	299.00
IUUC-Pva-102887	Pteropus vampyrus	32.59	1.00e-69	256.00
IUUC-Pgr-103513	Puccinia graminis	30.31	5.00e-114	404.00
IUUC-Ptt-103967	Puccinia triticina	40.20	3.00e-98	351.00
IUUC-Pte-104105	Pyrenophora teres	49.13	0.00e+00	1021.00
IUUC-Pyt-104449	Pyrenophora triticirepentis	49.61	0.00e+00	1013.00
IUUC-Rno-106028	Rattus norvegicus	30.14	4.00e-54	204.00
IUUC-Sce-106446	Saccharomyces cerevisiae	41.15	4.00e-84	304.00
IUUC-Sha-107108	Sarcophilus harrisii	34.42	3.00e-77	281.00
IUUC-Sja-107889	Schizosaccharomyces japonicus	33.14	6.00e-92	330.00
IUUC-Spo-108097	Schizosaccharomyces pombe	38.99	2.00e-101	362.00
IUUC-Ssl-108520	Sclerotinia sclerotiorum	45.14	0.00e+00	932.00
IUUC-Smo-109537	Selaginella moellendorffii	40.62	4.00e-86	311.00
IUUC-Sit-110457	Setaria italica	38.14	5.00e-76	277.00
IUUC-Sly-111362	Solanum lycopersicum	37.08	1.00e-74	273.00
IUUC-Sar-113687	Sorex araneus	35.28	3.00e-43	168.00
IUUC-Sbi-114433	Sorghum bicolor	36.64	6.00e-83	300.00
IUUC-Sre-115038	Sporisorium reilianum	43.88	8.00e-98	350.00
IUUC-Ssc-116103	Sus scrofa	32.38	1.00e-68	253.00
IUUC-Tgu-116729	Taeniopygia guttata	37.07	2.00e-90	325.00
IUUC-Tru-118068	Takifugu rubripes	37.93	2.00e-90	325.00
IUUC-Tsy-118942	Tarsius syrichta	44.36	4.00e-60	224.00
IUUC-Tni-120732	Tetraodon nigroviridis	37.18	2.00e-83	302.00
IUUC-Tca-121770	Theobroma cacao	39.33	1.00e-84	306.00
IUUC-Tre-121892	Trichoderma reesei	41.11	0.00e+00	754.00
IUUC-Tvi-122354	Trichoderma virens	39.47	0.00e+00	783.00
IUUC-Tae-125580	Triticum aestivum	37.50	2.00e-80	291.00
IUUC-Tur-126086	Triticum urartu	34.83	4.00e-81	295.00
IUUC-Tme-127102	Tuber melanosporum	40.20	0.00e+00	749.00
IUUC-Tbe-127351	Tupaia belangeri	38.41	7.00e-67	247.00
IUUC-Ttr-129061	Tursiops truncatus	41.69	6.00e-80	290.00
IUUC-Uma-129343	Ustilago maydis	43.46	4.00e-100	358.00
IUUC-Vda-129748	Verticillium dahliae	47.00	0.00e+00	685.00
IUUC-Vvi-131524	Vitis vinifera	40.00	3.00e-81	295.00
IUUC-Xtr-132094	Xenopus tropicalis	36.38	4.00e-87	314.00
IUUC-Xma-133923	Xiphophorus maculatus	37.76	2.00e-89	322.00
IUUC-Yli-134496	Yarrowia lipolytica	37.87	1.00e-92	332.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence