iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003249

Ensembl Protein ID

ENSAPLP00000001813.1

UniProt Accession

U3I3J2; U3I3J2_ANAPL

Genbank Protein ID

ENSAPLP00000001813

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01014286

Gene Name

USP15

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000001801.1	ENSAPLT00000002389.1	ENSAPLP00000001813.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.70e-119	398.6	258	902
ULD/UDP/UBQ/UBQ_Other	6.90e-09	35.2	117	187

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgye 88
           +Gl+NlgNtC+mNS++QcLsn+p+l+e++l+ k++e+ln +np ++ ge++ks+++l++++w++k ++v+pr+++++++++a++fsgy+
   Q: 258  CGLSNLGNTCFMNSAIQCLSNTPPLTEYFLNdKYQEELNFDNPLGMRGEIAKSYAELIKQMWSGKYSYVTPRAFKTQVGRFAPQFSGYQ 346
           7******************************9********************************************************* PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
           qqD+qE+laflld+l+e+l++ ++kp+ +++++d   ++d+     a+e++ k+n+s+i+d+F+g +ks+++c+ec+++s++++pf++l
   Q: 347  QQDCQELLAFLLDGLHEDLNRIRKKPYIQLKDAD--GRPDKvvaeeAWENHLKRNDSIIVDIFHGLFKSTLVCPECAKISVTFDPFCYL 433
           ******************************9999..5555555777******************************************* PP
   S: 173  slpvpgkeetkke............................................................................ 185
           +lp+p+k+e+ +e                                                                            
   Q: 434  TLPLPMKKERTLEvylvrmdplakpmqykvvvpkignildlctalsvlsgvaadkmivtdiynhrfhrifamdenlssimerddiyvfe 522
           *********9999**************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 523  iainrtedteqviipvclrekcrhtsyshsgsslfgqpfliavprnntedklynllllrmcryvktctesedtegslhcckdhgingng 611
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 612  pngiheegspsemetdeqddessqdqelpsenensqsedsvggdndsenglctedtckgqpltghkkrlftfqfnnlgntdinyikddt 700
           ***************************************************************************************** PP
   S: 186  .......................................................slqdcLesftkeeelegenkyycekckkkqeaek 219
                                                                  +l+dc+e ft++e+l  e+ +yc++ck++q+a+k
   Q: 701  rhirfddrqprldersflaldwdpelkkryfddraaedfekhesveykppkkpfvKLKDCIELFTTKEKLGAEDPWYCPNCKEHQQATK 789
           ***************************************************************************************** PP
   S: 220  klklkklPevLilhLkRfsfseeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.W 306
           kl+l++lP+vL++hLkRfs+s+  ++r k+++ v+fp++ Ld+s+f+++p+ +   +++Y+Liav +H+G++++GHY+a++kn++++ W
   Q: 790  KLDLWSLPPVLVVHLKRFSYSR--YMRDKLDTLVDFPINdLDMSEFLINPNAG---PCRYNLIAVSNHYGGMGGGHYTAFAKNKDDGkW 873
           ******************9977..6999*********************9988...8**************************65555* PP
   S: 307  llfdDskVtevkeeevleetgstaYvlfYkrr 338
           ++fdDs+V++  e+++++   + aYvlfY+r+
   Q: 874  YYFDDSSVSTACEDQIVS---KAAYVLFYQRQ 902
           ******************...*********96 PP

ULD/UDP/UBQ/UBQ_Other

   S: 12   eltlkvnpsdtVaeLKekiekklgip.peqqrLiyk.....GkiL.eddktLadyglkdgstihllekksg 75
           + t++++++dt+ ++ ++i+k ++ip + + rL++k      ++L ++d t++d gl++g+++++++k+++
   Q: 117  VVTRRFSKADTIDTIEKEIRKIFNIPgEKETRLWNKymsntFEPLnKPDSTIQDAGLYQGQVLVIEQKNED 187
           77899*********************888*****998875544569*********************9986 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

YLVDSRWFKQ WKKYVGFDSW DKYQMGDQNV YPGPIDNSGL LKDGDSQSLK EHLIDELDYI 60
LLPTEGWNRL VSWYTLMEGQ EPIARKVVEQ GMFVKHCKVE VYLTELKLCE NGNMNNVVTR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TATCTAGTGG ATAGTCGCTG GTTCAAACAG TGGAAAAAAT ATGTTGGTTT TGACAGCTGG 60
GACAAATACC AGATGGGAGA TCAGAATGTG TACCCTGGTC CTATTGATAA TTCTGGACTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR029071--Ubiquitin-rel_dom
IPR029346--USP_C
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF14836--Ubiquitin_3
PF00443--UCH
PF14533--USP7_C2

SMART

SM00695--DUSP

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0030509--P:BMP signaling pathway
GO:0035616--P:histone H2B conserved C-terminal lysine deubiquitination
GO:0035520--P:monoubiquitinated protein deubiquitination
GO:0060389--P:pathway-restricted SMAD protein phosphorylation
GO:0007179--P:transforming growth factor beta receptor signaling pathway
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000425	Aegilops tauschii	39.43	3.00e-105	376.00
IUUC-Aml-001852	Ailuropoda melanoleuca	94.34	0.00e+00	1767.00
IUUC-Aca-004261	Anolis carolinensis	95.17	0.00e+00	1699.00
IUUC-Aly-006315	Arabidopsis lyrata	37.72	3.00e-92	332.00
IUUC-Ago-007911	Ashbya gossypii	37.32	4.00e-60	226.00
IUUC-Acl-008284	Aspergillus clavatus	37.50	3.00e-55	210.00
IUUC-Afl-008507	Aspergillus flavus	37.63	1.00e-54	208.00
IUUC-Afu-008878	Aspergillus fumigatus	38.06	6.00e-55	209.00
IUUC-Ani-009479	Aspergillus nidulans	42.91	1.00e-51	198.00
IUUC-Ang-009562	Aspergillus niger	36.41	3.00e-55	211.00
IUUC-Aor-009949	Aspergillus oryzae	37.40	2.00e-53	204.00
IUUC-Ate-010323	Aspergillus terreus	36.95	5.00e-55	209.00
IUUC-Ame-010757	Astyanax mexicanus	78.86	0.00e+00	1278.00
IUUC-Bgr-012277	Blumeria graminis	42.40	2.00e-62	235.00
IUUC-Bta-013128	Bos taurus	93.17	0.00e+00	1746.00
IUUC-Bci-013993	Botrytis cinerea	42.47	2.00e-62	234.00
IUUC-Bdi-015062	Brachypodium distachyon	39.38	9.00e-123	434.00
IUUC-Cel-018203	Caenorhabditis elegans	58.91	2.00e-69	256.00
IUUC-Cja-019222	Callithrix jacchus	94.65	0.00e+00	1773.00
IUUC-Cfa-020035	Canis familiaris	94.44	0.00e+00	1767.00
IUUC-Cpo-022071	Cavia porcellus	94.51	0.00e+00	1692.00
IUUC-Csa-023882	Chlorocebus sabaeus	94.96	0.00e+00	1778.00
IUUC-Cin-025292	Ciona intestinalis	44.88	0.00e+00	724.00
IUUC-Csv-026109	Ciona savignyi	47.87	2.00e-149	522.00
IUUC-Cgl-026741	Colletotrichum gloeosporioides	34.58	1.00e-59	225.00
IUUC-Cne-026852	Cryptococcus neoformans	46.62	1.00e-71	265.00
IUUC-Cme-027338	Cyanidioschyzon merolae	56.36	3.00e-68	253.00
IUUC-Dre-027869	Danio rerio	57.68	0.00e+00	1055.00
IUUC-Dno-029025	Dasypus novemcinctus	91.71	0.00e+00	1710.00
IUUC-Dor-030956	Dipodomys ordii	86.04	0.00e+00	1567.00
IUUC-Dse-031432	Dothistroma septosporum	40.43	2.00e-58	221.00
IUUC-Eca-034340	Equus caballus	94.75	0.00e+00	1774.00
IUUC-Eeu-034488	Erinaceus europaeus	84.82	0.00e+00	1160.00
IUUC-Fca-035552	Felis catus	92.75	0.00e+00	1730.00
IUUC-Fal-036618	Ficedula albicollis	99.37	0.00e+00	1781.00
IUUC-Fox-037986	Fusarium oxysporum	42.05	1.00e-61	232.00
IUUC-Fso-038291	Fusarium solani	43.59	3.00e-63	237.00
IUUC-Ggr-039740	Gaeumannomyces graminis	42.49	3.00e-60	227.00
IUUC-Gga-041146	Gallus gallus	98.53	0.00e+00	1773.00
IUUC-Gac-041679	Gasterosteus aculeatus	77.37	0.00e+00	1421.00
IUUC-Gma-043077	Glycine max	37.29	1.00e-152	533.00
IUUC-Ggo-045002	Gorilla gorilla	94.76	0.00e+00	1770.00
IUUC-Hsa-046052	Homo sapiens	94.86	0.00e+00	1777.00
IUUC-Hvu-047108	Hordeum vulgare	39.82	3.00e-121	428.00
IUUC-Itr-048306	Ictidomys tridecemlineatus	92.98	0.00e+00	1737.00
IUUC-Kpa-049332	Komagataella pastoris	33.39	2.00e-68	253.00
IUUC-Lch-050107	Latimeria chalumnae	87.51	0.00e+00	1705.00
IUUC-Lpe-051185	Leersia perrieri	40.37	2.00e-124	439.00
IUUC-Loc-052105	Lepisosteus oculatus	83.48	0.00e+00	1471.00
IUUC-Lma-052981	Leptosphaeria maculans	34.33	6.00e-66	246.00
IUUC-Laf-053645	Loxodonta africana	93.92	0.00e+00	1762.00
IUUC-Mcc-055586	Macaca mulatta	94.86	0.00e+00	1777.00
IUUC-Meu-056764	Macropus eugenii	89.47	0.00e+00	993.00
IUUC-Mor-056985	Magnaporthe oryzae	41.76	7.00e-60	226.00
IUUC-Mpo-057486	Magnaporthe poae	42.49	7.00e-60	226.00
IUUC-Mtr-058138	Medicago truncatula	37.78	9.00e-156	543.00
IUUC-Mla-058848	Melampsora laricipopulina	39.12	8.00e-67	249.00
IUUC-Mga-060162	Meleagris gallopavo	98.84	0.00e+00	1778.00
IUUC-Mvi-060324	Microbotryum violaceum	38.22	2.00e-71	264.00
IUUC-Mmr-061105	Microcebus murinus	94.86	0.00e+00	1774.00
IUUC-Mdo-062107	Monodelphis domestica	95.07	0.00e+00	1764.00
IUUC-Mmu-063662	Mus musculus	93.28	0.00e+00	1753.00
IUUC-Mpu-065868	Mustela putorius furo	92.39	0.00e+00	1758.00
IUUC-Mlu-068000	Myotis lucifugus	88.02	0.00e+00	1621.00
IUUC-Nfi-068330	Neosartorya fischeri	38.38	1.00e-55	211.00
IUUC-Ncr-068879	Neurospora crassa	44.89	1.00e-59	224.00
IUUC-Nle-069874	Nomascus leucogenys	94.89	0.00e+00	1754.00
IUUC-Opr-071212	Ochotona princeps	89.03	0.00e+00	1659.00
IUUC-Ont-071834	Oreochromis niloticus	78.78	0.00e+00	1412.00
IUUC-Ocu-074573	Oryctolagus cuniculus	95.07	0.00e+00	1781.00
IUUC-Oba-075553	Oryza barthii	39.76	1.00e-125	444.00
IUUC-Obr-076410	Oryza brachyantha	39.70	3.00e-124	438.00
IUUC-Ogl-077583	Oryza glaberrima	39.76	1.00e-125	444.00
IUUC-Ogu-077990	Oryza glumaepatula	39.18	2.00e-120	426.00
IUUC-Oin-079300	Oryza indica	39.91	1.00e-126	447.00
IUUC-Olo-080387	Oryza longistaminata	39.38	1.00e-119	423.00
IUUC-Ome-081963	Oryza meridionalis	38.33	4.00e-118	419.00
IUUC-Oni-082303	Oryza nivara	39.49	3.00e-121	429.00
IUUC-Opu-083770	Oryza punctata	39.97	2.00e-126	446.00
IUUC-Oru-085141	Oryza rufipogon	39.57	6.00e-123	435.00
IUUC-Osa-085641	Oryza sativa	39.91	1.00e-126	447.00
IUUC-Oga-089022	Otolemur garnettii	92.75	0.00e+00	1737.00
IUUC-Oar-089767	Ovis aries	94.44	0.00e+00	1771.00
IUUC-Ptr-091319	Pan troglodytes	93.49	0.00e+00	1749.00
IUUC-Pan-091968	Papio anubis	94.96	0.00e+00	1778.00
IUUC-Psi-093849	Pelodiscus sinensis	96.74	0.00e+00	1740.00
IUUC-Pma-094533	Petromyzon marinus	59.22	0.00e+00	1059.00
IUUC-Pno-094890	Phaeosphaeria nodorum	32.47	3.00e-59	224.00
IUUC-Pfo-097110	Poecilia formosa	77.98	0.00e+00	1411.00
IUUC-Pab-098664	Pongo abelii	94.96	0.00e+00	1778.00
IUUC-Pop-099801	Populus trichocarpa	36.25	1.00e-148	520.00
IUUC-Pca-100359	Procavia capensis	76.35	0.00e+00	1274.00
IUUC-Ppe-101587	Prunus persica	37.13	1.00e-146	513.00
IUUC-Pva-102394	Pteropus vampyrus	93.07	0.00e+00	1732.00
IUUC-Pgr-103546	Puccinia graminis	29.42	2.00e-66	248.00
IUUC-Ptt-103847	Puccinia triticina	38.18	1.00e-60	228.00
IUUC-Pte-104102	Pyrenophora teres	36.07	4.00e-56	214.00
IUUC-Pyt-104812	Pyrenophora triticirepentis	39.56	2.00e-55	211.00
IUUC-Rno-105383	Rattus norvegicus	92.23	0.00e+00	1730.00
IUUC-Sce-106170	Saccharomyces cerevisiae	36.99	1.00e-60	228.00
IUUC-Sha-107393	Sarcophilus harrisii	95.17	0.00e+00	1771.00
IUUC-Sja-107752	Schizosaccharomyces japonicus	35.91	2.00e-80	293.00
IUUC-Spo-108291	Schizosaccharomyces pombe	42.86	3.00e-73	269.00
IUUC-Ssl-108461	Sclerotinia sclerotiorum	31.11	5.00e-14	72.80
IUUC-Smo-108686	Selaginella moellendorffii	47.62	1.00e-80	293.00
IUUC-Sit-109948	Setaria italica	36.94	2.00e-140	493.00
IUUC-Sly-111726	Solanum lycopersicum	39.81	7.00e-91	328.00
IUUC-Stu-112671	Solanum tuberosum	36.63	6.00e-145	508.00
IUUC-Sar-113498	Sorex araneus	94.33	0.00e+00	1766.00
IUUC-Sbi-114031	Sorghum bicolor	39.91	1.00e-118	420.00
IUUC-Sre-115130	Sporisorium reilianum	43.06	2.00e-76	281.00
IUUC-Ssc-115285	Sus scrofa	94.76	0.00e+00	1771.00
IUUC-Tgu-116529	Taeniopygia guttata	99.26	0.00e+00	1786.00
IUUC-Tru-118298	Takifugu rubripes	76.87	0.00e+00	1430.00
IUUC-Tsy-119117	Tarsius syrichta	85.99	0.00e+00	1101.00
IUUC-Tni-120093	Tetraodon nigroviridis	75.44	0.00e+00	1363.00
IUUC-Tre-121888	Trichoderma reesei	41.73	7.00e-62	233.00
IUUC-Tvi-122422	Trichoderma virens	39.21	2.00e-56	215.00
IUUC-Tae-123874	Triticum aestivum	39.54	2.00e-119	422.00
IUUC-Tur-126149	Triticum urartu	39.70	1.00e-105	377.00
IUUC-Tbe-127672	Tupaia belangeri	91.93	0.00e+00	1163.00
IUUC-Vda-129781	Verticillium dahliae	37.01	2.00e-64	241.00
IUUC-Vpa-130469	Vicugna pacos	94.33	0.00e+00	1758.00
IUUC-Vvi-131010	Vitis vinifera	38.16	3.00e-150	525.00
IUUC-Xtr-132729	Xenopus tropicalis	83.42	0.00e+00	1574.00
IUUC-Xma-133550	Xiphophorus maculatus	77.98	0.00e+00	1407.00
IUUC-Yli-134392	Yarrowia lipolytica	38.57	8.00e-63	235.00
IUUC-Zma-135699	Zea mays	35.83	8.00e-141	494.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence