iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Hvu-047146

Ensembl Protein ID

MLOC_43219.1

UniProt Accession

M0W3V6; M0W3V6_HORVV

Protein Name

Ubiquitinyl hydrolase 1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
MLOC_43219	MLOC_43219.1	MLOC_43219.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	7.80e-72	243.4	207	658

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgyeqqDaqEf 95
           +Gl NlgNtC++N+vLQ+L+++  +r+ +l           p+ p g++++sl+klf e    ++  +a sp++l+++++++ ++f+gy+ qD++E+
   Q: 207  KGLPNLGNTCFFNAVLQSLLALDRFRSKMLG----------PDVPAGAIAMSLKKLFVETSasNDAGGALSPKSLFSSICSKYPQFKGYQMQDSHEL 293
           59*****************************..........345789**********99987788888***************************** PP
   S: 96   laflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke....... 185
           l+++ld+l +e ++                + + +e+      +++++ +F+gql+s++   ec++ s+++++fldlslpvp+k+  +k+       
   Q: 294  LRCFLDGLGTEETE----------------ARKAEEDASSAGVPTIVDSIFGGQLSSTVSSTECAHGSVKHDQFLDLSLPVPSKRPPAKSvssppak 374
           **********9922................23334567889999****************************************98888899***** PP
   S: 186  ................................................................................................. 185
                                                                                                            
   Q: 375  rtkqsirdrnknrrygkiptrvspaiaesskekiqtvaegndsqipgselgqvvseketepsecsescasvpnqelktacnveadiswldylgdade 471
           ************************************************************************************************* PP
   S: 186  ................................................................................................. 185
                                                                                                            
   Q: 472  tkseildsacstgagqiwnsndaihgsfnsgddalpkeqalisehssekivddatclptvillpykeiettaeeiyetaessqhpivfgphpadyla 568
           ************************************************************************************************* PP
   S: 186  .................................................................slqdcLesftkeeelegenkyycekck 212
                                                                            s++ cL+ +t++e l +   ++ce+c 
   Q: 569  aennaqplyggdgeqddcfgigdmfgetevtsdvkketgttgdidvmawssnsaddevddsnapvSVEGCLSLYTEPELLSE--SWHCEHCS 658
           ********************************************************************************85..8******7 PP

Organism

Hordeum vulgare

Protein Sequence
(Fasta)

MGKKVKAKAK KAQQREPPAD AGSGDEASQD VEEAAAPAGD WEQCGHYSRD SRHLDKLLRE 60
IVSAKHLASC EHCREEAPRK KGGGGGKDKG GKQQKKKGAA AKTQAKADKN DDFWVCLDCG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACTACGAGTA TTGTTCATAC CCAACCGGCC AACTCGTATT CGTAGTCCCG TGGCACGCCT 60
TCCTTTGTCC TCTTGGTGTC GCGCACCAGC GCCCCCCAAT CCCCACCACC CAGTGCGACG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00443--UCH
PF02148--zf-UBP

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000997	Aegilops tauschii	93.96	0.00e+00	1770.00
IUUC-Aml-001931	Ailuropoda melanoleuca	36.28	3.00e-30	125.00
IUUC-Atr-003015	Amborella trichopoda	31.91	4.00e-55	209.00
IUUC-Apl-004145	Anas platyrhynchos	35.53	4.00e-28	119.00
IUUC-Aca-004314	Anolis carolinensis	36.76	2.00e-25	109.00
IUUC-Aly-006422	Arabidopsis lyrata	37.27	6.00e-47	181.00
IUUC-Ath-007211	Arabidopsis thaliana	35.97	1.00e-47	184.00
IUUC-Ame-011659	Astyanax mexicanus	30.70	2.00e-24	106.00
IUUC-Bta-013362	Bos taurus	36.28	6.00e-30	124.00
IUUC-Bdi-014465	Brachypodium distachyon	74.18	0.00e+00	1377.00
IUUC-Bol-015191	Brassica oleracea	38.25	2.00e-53	203.00
IUUC-Bra-016751	Brassica rapa	39.44	3.00e-47	182.00
IUUC-Cja-019177	Callithrix jacchus	35.81	3.00e-30	125.00
IUUC-Cfa-020051	Canis familiaris	31.07	7.00e-31	127.00
IUUC-Cpo-021886	Cavia porcellus	36.55	1.00e-28	120.00
IUUC-Csa-024103	Chlorocebus sabaeus	35.81	2.00e-30	126.00
IUUC-Cho-024315	Choloepus hoffmanni	40.18	2.00e-18	86.70
IUUC-Cin-025775	Ciona intestinalis	32.41	5.00e-16	75.10
IUUC-Csv-026075	Ciona savignyi	31.48	2.00e-17	83.20
IUUC-Cme-027348	Cyanidioschyzon merolae	36.30	1.00e-18	87.00
IUUC-Dre-028388	Danio rerio	34.52	4.00e-26	112.00
IUUC-Dno-029409	Dasypus novemcinctus	36.06	2.00e-29	123.00
IUUC-Dor-030443	Dipodomys ordii	36.24	4.00e-23	102.00
IUUC-Ete-032807	Echinops telfairi	36.00	2.00e-23	103.00
IUUC-Eca-033479	Equus caballus	35.81	1.00e-30	127.00
IUUC-Eeu-034835	Erinaceus europaeus	32.43	3.00e-23	102.00
IUUC-Fca-036320	Felis catus	36.28	8.00e-31	127.00
IUUC-Fal-037029	Ficedula albicollis	30.31	9.00e-32	130.00
IUUC-Gmo-039480	Gadus morhua	34.30	2.00e-25	109.00
IUUC-Gga-040527	Gallus gallus	35.42	1.00e-25	110.00
IUUC-Gac-042343	Gasterosteus aculeatus	32.03	1.00e-25	110.00
IUUC-Gma-044402	Glycine max	32.30	2.00e-75	276.00
IUUC-Ggo-045598	Gorilla gorilla	35.35	1.00e-29	123.00
IUUC-Hsa-046598	Homo sapiens	35.35	2.00e-29	123.00
IUUC-Itr-047951	Ictidomys tridecemlineatus	35.29	6.00e-31	127.00
IUUC-Lch-050536	Latimeria chalumnae	36.41	3.00e-28	119.00
IUUC-Lpe-050703	Leersia perrieri	66.79	0.00e+00	1199.00
IUUC-Loc-051814	Lepisosteus oculatus	36.10	2.00e-27	116.00
IUUC-Laf-053732	Loxodonta africana	28.94	4.00e-32	132.00
IUUC-Mcc-054661	Macaca mulatta	35.81	2.00e-30	126.00
IUUC-Meu-055967	Macropus eugenii	42.24	2.00e-18	86.70
IUUC-Mtr-057945	Medicago truncatula	39.05	2.00e-54	206.00
IUUC-Mla-059026	Melampsora laricipopulina	36.36	5.00e-19	88.20
IUUC-Mga-059551	Meleagris gallopavo	29.00	1.00e-30	126.00
IUUC-Mvi-060391	Microbotryum violaceum	33.91	1.00e-18	87.40
IUUC-Mmr-061747	Microcebus murinus	35.81	2.00e-30	126.00
IUUC-Mdo-062220	Monodelphis domestica	29.70	4.00e-28	118.00
IUUC-Mmu-063582	Mus musculus	35.35	1.00e-28	120.00
IUUC-Mac-064941	Musa acuminata	48.62	6.00e-82	297.00
IUUC-Mpu-066339	Mustela putorius furo	31.07	8.00e-31	127.00
IUUC-Mlu-067511	Myotis lucifugus	35.81	2.00e-30	126.00
IUUC-Nle-069252	Nomascus leucogenys	35.81	2.00e-30	126.00
IUUC-Opr-070969	Ochotona princeps	35.81	4.00e-29	122.00
IUUC-Ont-071786	Oreochromis niloticus	33.50	1.00e-24	107.00
IUUC-Oan-073656	Ornithorhynchus anatinus	28.98	2.00e-26	112.00
IUUC-Ocu-074704	Oryctolagus cuniculus	35.81	4.00e-30	125.00
IUUC-Oba-075094	Oryza barthii	70.24	0.00e+00	1257.00
IUUC-Obr-076743	Oryza brachyantha	68.20	0.00e+00	1180.00
IUUC-Ogl-077739	Oryza glaberrima	67.51	0.00e+00	995.00
IUUC-Ogu-078851	Oryza glumaepatula	70.24	0.00e+00	1257.00
IUUC-Oin-079402	Oryza indica	70.24	0.00e+00	1257.00
IUUC-Olo-080431	Oryza longistaminata	70.25	0.00e+00	1229.00
IUUC-Ome-081580	Oryza meridionalis	69.64	0.00e+00	1246.00
IUUC-Oni-082644	Oryza nivara	70.24	0.00e+00	1257.00
IUUC-Opu-083452	Oryza punctata	70.36	0.00e+00	1259.00
IUUC-Oru-084546	Oryza rufipogon	70.34	0.00e+00	1257.00
IUUC-Osa-085858	Oryza sativa	70.04	0.00e+00	1251.00
IUUC-Ola-086795	Oryzias latipes	33.02	8.00e-25	107.00
IUUC-Oga-088713	Otolemur garnettii	35.81	1.00e-30	127.00
IUUC-Oar-089971	Ovis aries	36.28	1.00e-29	124.00
IUUC-Ptr-091670	Pan troglodytes	35.35	7.00e-30	124.00
IUUC-Pan-092293	Papio anubis	35.81	2.00e-30	126.00
IUUC-Psi-093101	Pelodiscus sinensis	35.35	9.00e-27	114.00
IUUC-Ppa-095622	Physcomitrella patens	29.65	2.00e-37	150.00
IUUC-Pfo-097202	Poecilia formosa	35.86	3.00e-27	116.00
IUUC-Pab-098773	Pongo abelii	35.35	1.00e-29	123.00
IUUC-Pop-099588	Populus trichocarpa	29.66	5.00e-59	221.00
IUUC-Pca-101069	Procavia capensis	32.80	9.00e-24	104.00
IUUC-Ppe-101794	Prunus persica	40.38	2.00e-63	236.00
IUUC-Pva-103092	Pteropus vampyrus	35.14	8.00e-25	107.00
IUUC-Rno-105237	Rattus norvegicus	34.42	4.00e-28	118.00
IUUC-Sha-106889	Sarcophilus harrisii	38.58	3.00e-27	115.00
IUUC-Sja-107712	Schizosaccharomyces japonicus	32.89	6.00e-19	88.20
IUUC-Spo-108149	Schizosaccharomyces pombe	36.97	1.00e-23	103.00
IUUC-Sit-110283	Setaria italica	66.57	0.00e+00	1241.00
IUUC-Sly-111491	Solanum lycopersicum	36.44	4.00e-59	221.00
IUUC-Stu-112820	Solanum tuberosum	34.15	1.00e-62	233.00
IUUC-Sar-113530	Sorex araneus	29.50	3.00e-30	125.00
IUUC-Sbi-113785	Sorghum bicolor	65.92	0.00e+00	1168.00
IUUC-Ssc-116091	Sus scrofa	36.06	2.00e-29	123.00
IUUC-Tgu-117478	Taeniopygia guttata	31.89	1.00e-30	127.00
IUUC-Tru-118640	Takifugu rubripes	34.31	1.00e-25	110.00
IUUC-Tsy-118869	Tarsius syrichta	37.13	4.00e-25	108.00
IUUC-Tni-120015	Tetraodon nigroviridis	34.12	6.00e-27	114.00
IUUC-Tca-121701	Theobroma cacao	30.04	4.00e-66	245.00
IUUC-Tae-125305	Triticum aestivum	94.25	0.00e+00	1735.00
IUUC-Tur-126788	Triticum urartu	93.39	0.00e+00	1545.00
IUUC-Tbe-128041	Tupaia belangeri	36.14	1.00e-24	107.00
IUUC-Ttr-128271	Tursiops truncatus	35.35	2.00e-30	126.00
IUUC-Vpa-130674	Vicugna pacos	36.28	1.00e-30	127.00
IUUC-Xtr-131869	Xenopus tropicalis	35.64	4.00e-27	115.00
IUUC-Xma-134195	Xiphophorus maculatus	37.88	2.00e-27	116.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence