iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bra-016726

Ensembl Protein ID

Bra027850.1-P

UniProt Accession

M4EGD6; M4EGD6_BRARP

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Bra027850	Bra027850.1	Bra027850.1-P

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	8.30e-120	401.2	3445	3783
UBD/Alpha-Helix/UBA	1.70e-08	35.3	1271	1310

Active Site

Position(s)	Description	Evidence
3751	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksf 96
           ++lk rl v+f+gEeg+d+gG+tre+++lls+ ++++ + lf++  ++++t+qpnp+s ++ +ehl++F+f+Gr++gkal+dg+lld+++++sf
   Q: 3445 QELKGRLTVHFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFTTV-GNDSTFQPNPNSVYQ-TEHLSYFKFVGRVVGKALFDGQLLDVHFTRSF 3536
           7899**********************************9999555.566778******986.5******************************* PP
   S: 97   yklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseei.......lgetkeeeLkpgGenipVtneNkeeYvklvveyrlk 183
           yk++lg+k++++d+e++dp++yk lk+++en   di++  ldltfsv+ ++         e++++eL+pgG+ni+Vt+eNk+eYv+l++e+rl+
   Q: 3537 YKHILGVKVTYHDIEAIDPDYYKALKWMLEN---DISDV-LDLTFSVDADEeklilyeKTEVTDHELIPGGRNIKVTEENKHEYVDLIAEHRLT 3626
           *****************************99...99998.99999988877789995555566788**************************** PP
   S: 184  egikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlg 277
           + i+ q++af eGf+e+i ++l+s+F+ +elelli+G ++id+++l+++t+y +gy++ sp+iqwFwev++++s+e+++++LqFvTg+s++Pl+
   Q: 3627 TAIRPQINAFLEGFSELILKDLISIFNDKELELLISGLPDIDLDNLRANTEY-SGYSPGSPVIQWFWEVVQGLSKEDKARLLQFVTGTSKVPLE 3719
           ****************************************************.55*************************************** PP
   S: 278  Gfaelk....prlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kgFel 335
           Gf +l+     ++f+i+k ++s ++lPs++TCfn+L+LPeY+ske l+e+Ll+Ai+e+ +gF++
   Q: 3720 GFSSLQgisgAQKFQIHKaYGSANHLPSAHTCFNQLDLPEYPSKEHLQERLLLAIHEAsEGFGF 3783
           **********9*******99999***********************************9***85 PP

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGFdreealqaLraa.nnnleaAveyLldg 41
           +e  +  +veMGF+r++a +aLr+  +n++e A+e+L+++
   Q: 1271 SETTISTIVEMGFSRSRAEEALRQVgSNSVELAMEWLFSH 1310
           5788999*******************************97 PP

Organism

Brassica rapa

Protein Sequence
(Fasta)

MATGRSASMP SRLRQLLSCE GSIGPSIRRD AEPPPEIKSF IEKVIQSPLS DIAIPLSGFR 60
WEYSKGNFHH WRPLFLHFDK YFKTFLSTRN DLLLSDHILE DEDPFPKYSL LQILRVMQII 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGACTG GGAGATCCGC AAGTATGCCG TCACGGTTGC GGCAGCTTCT TTCCTGCGAA 60
GGCTCCATCG GCCCCTCTAT TAGGCGCGAC GCTGAGCCTG TGAGTTCTCT CAAATTCGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR025527--DUF4414
IPR010309--E3_Ub_ligase_DUF908
IPR010314--E3_Ub_ligase_DUF913
IPR000569--HECT_dom
IPR015940--UBA
IPR009060--UBA-like
IPR003903--UIM_dom

PROSITE

PS50237--HECT
PS50030--UBA
PS50330--UIM

Pfam

PF14377--DUF4414
PF06012--DUF908
PF06025--DUF913
PF00632--HECT
PF00627--UBA

SMART

SM00119--HECTc
SM00165--UBA

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000627	Aegilops tauschii	54.22	0.00e+00	1871.00
IUUC-Atr-002582	Amborella trichopoda	57.79	0.00e+00	2068.00
IUUC-Apl-003400	Anas platyrhynchos	44.55	7.00e-102	364.00
IUUC-Aly-006157	Arabidopsis lyrata	85.32	0.00e+00	3184.00
IUUC-Ago-008005	Ashbya gossypii	40.49	4.00e-133	470.00
IUUC-Acl-008254	Aspergillus clavatus	43.53	9.00e-141	496.00
IUUC-Afl-008712	Aspergillus flavus	44.97	4.00e-141	495.00
IUUC-Afu-009022	Aspergillus fumigatus	43.06	2.00e-140	495.00
IUUC-Ani-009412	Aspergillus nidulans	44.84	2.00e-140	495.00
IUUC-Ang-009771	Aspergillus niger	44.52	4.00e-140	494.00
IUUC-Aor-010186	Aspergillus oryzae	44.24	5.00e-131	462.00
IUUC-Ate-010253	Aspergillus terreus	44.33	4.00e-140	494.00
IUUC-Bgr-012043	Blumeria graminis	48.76	2.00e-137	485.00
IUUC-Bci-013995	Botrytis cinerea	41.44	5.00e-139	490.00
IUUC-Bdi-014884	Brachypodium distachyon	55.39	0.00e+00	1961.00
IUUC-Bol-015228	Brassica oleracea	94.43	0.00e+00	3173.00
IUUC-Cel-018179	Caenorhabditis elegans	47.26	2.00e-119	425.00
IUUC-Cpo-021766	Cavia porcellus	44.55	9.00e-102	364.00
IUUC-Cre-022900	Chlamydomonas reinhardtii	61.02	1.00e-158	552.00
IUUC-Cin-025627	Ciona intestinalis	50.35	1.00e-122	436.00
IUUC-Csv-025872	Ciona savignyi	49.88	2.00e-118	418.00
IUUC-Cme-027267	Cyanidioschyzon merolae	53.76	3.00e-132	466.00
IUUC-Dse-031197	Dothistroma septosporum	41.82	3.00e-139	491.00
IUUC-Ete-032966	Echinops telfairi	44.09	7.00e-102	364.00
IUUC-Fal-036687	Ficedula albicollis	45.02	2.00e-102	366.00
IUUC-Fox-037756	Fusarium oxysporum	33.13	3.00e-157	551.00
IUUC-Fso-038464	Fusarium solani	48.45	9.00e-138	486.00
IUUC-Ggr-039946	Gaeumannomyces graminis	43.07	7.00e-137	483.00
IUUC-Gga-040845	Gallus gallus	44.77	3.00e-102	366.00
IUUC-Gma-044216	Glycine max	63.62	0.00e+00	2308.00
IUUC-Ggo-044465	Gorilla gorilla	44.22	4.00e-100	359.00
IUUC-Hvu-047697	Hordeum vulgare	54.85	0.00e+00	1900.00
IUUC-Kpa-049228	Komagataella pastoris	45.02	3.00e-135	477.00
IUUC-Lpe-051550	Leersia perrieri	56.05	0.00e+00	1912.00
IUUC-Lma-053159	Leptosphaeria maculans	32.39	2.00e-148	521.00
IUUC-Meu-056751	Macropus eugenii	45.45	2.00e-79	290.00
IUUC-Mpo-057597	Magnaporthe poae	42.62	2.00e-136	482.00
IUUC-Mtr-057633	Medicago truncatula	64.35	0.00e+00	2393.00
IUUC-Mla-058888	Melampsora laricipopulina	48.42	6.00e-117	413.00
IUUC-Mga-059935	Meleagris gallopavo	44.77	4.00e-102	365.00
IUUC-Mvi-060320	Microbotryum violaceum	46.93	1.00e-129	459.00
IUUC-Mac-065499	Musa acuminata	55.44	0.00e+00	1991.00
IUUC-Nfi-068278	Neosartorya fischeri	43.22	3.00e-141	497.00
IUUC-Ncr-068813	Neurospora crassa	45.90	9.00e-146	513.00
IUUC-Opr-071044	Ochotona princeps	45.45	9.00e-95	341.00
IUUC-Oba-075757	Oryza barthii	56.39	0.00e+00	1873.00
IUUC-Obr-076553	Oryza brachyantha	55.94	0.00e+00	1941.00
IUUC-Ogl-077520	Oryza glaberrima	56.64	0.00e+00	1972.00
IUUC-Ogu-078278	Oryza glumaepatula	56.62	0.00e+00	1972.00
IUUC-Oin-079767	Oryza indica	56.37	0.00e+00	1952.00
IUUC-Olo-080380	Oryza longistaminata	55.95	0.00e+00	1955.00
IUUC-Ome-081925	Oryza meridionalis	56.54	0.00e+00	1961.00
IUUC-Oni-082619	Oryza nivara	56.54	0.00e+00	1967.00
IUUC-Opu-083684	Oryza punctata	56.41	0.00e+00	1966.00
IUUC-Oru-084501	Oryza rufipogon	56.64	0.00e+00	1972.00
IUUC-Ola-086777	Oryzias latipes	44.87	1.00e-102	367.00
IUUC-Olu-087813	Ostreococcus lucimarinus	51.58	4.00e-125	440.00
IUUC-Ptr-090529	Pan troglodytes	44.32	2.00e-101	363.00
IUUC-Psi-093969	Pelodiscus sinensis	44.32	5.00e-101	362.00
IUUC-Pma-094364	Petromyzon marinus	44.72	5.00e-90	324.00
IUUC-Pno-094871	Phaeosphaeria nodorum	41.63	9.00e-138	486.00
IUUC-Pop-099468	Populus trichocarpa	66.85	0.00e+00	2446.00
IUUC-Pca-100568	Procavia capensis	44.13	2.00e-87	317.00
IUUC-Ppe-101641	Prunus persica	65.87	0.00e+00	2365.00
IUUC-Pgr-103465	Puccinia graminis	46.33	6.00e-130	460.00
IUUC-Ptt-103813	Puccinia triticina	43.76	6.00e-120	427.00
IUUC-Pte-104018	Pyrenophora teres	33.39	1.00e-149	525.00
IUUC-Pyt-104713	Pyrenophora triticirepentis	33.22	7.00e-144	506.00
IUUC-Rno-105153	Rattus norvegicus	44.32	8.00e-102	364.00
IUUC-Sce-106449	Saccharomyces cerevisiae	40.61	2.00e-127	451.00
IUUC-Ssl-108514	Sclerotinia sclerotiorum	44.50	3.00e-93	335.00
IUUC-Sit-110598	Setaria italica	55.30	0.00e+00	1897.00
IUUC-Sly-111706	Solanum lycopersicum	61.69	0.00e+00	2302.00
IUUC-Sbi-114042	Sorghum bicolor	54.48	0.00e+00	1888.00
IUUC-Sre-114958	Sporisorium reilianum	50.82	2.00e-144	506.00
IUUC-Tgu-117225	Taeniopygia guttata	44.80	2.00e-102	366.00
IUUC-Tsy-119407	Tarsius syrichta	48.12	2.00e-95	343.00
IUUC-Tca-121479	Theobroma cacao	68.11	0.00e+00	2529.00
IUUC-Tre-121909	Trichoderma reesei	39.05	4.00e-146	514.00
IUUC-Tvi-122370	Trichoderma virens	38.08	5.00e-143	503.00
IUUC-Tae-125214	Triticum aestivum	59.40	0.00e+00	1546.00
IUUC-Tme-127172	Tuber melanosporum	42.69	2.00e-137	485.00
IUUC-Tbe-127762	Tupaia belangeri	42.56	8.00e-85	308.00
IUUC-Uma-129355	Ustilago maydis	51.63	8.00e-148	516.00
IUUC-Vda-129886	Verticillium dahliae	48.34	4.00e-137	484.00
IUUC-Vvi-131078	Vitis vinifera	66.11	0.00e+00	2140.00
IUUC-Zma-135581	Zea mays	53.91	0.00e+00	1863.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence