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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Ath-006582
Ensembl Protein ID AT5G45110.1
UniProt Accession Q8L746; Q9FHE3; NPR3_ARATH
Genbank Protein ID BAB09496.1; AED95205.1; AAM98084.1; AAO42783.1
Protein Name Regulatory protein NPR3; BTB/POZ domain-containing protein NPR3
Genbank Nucleotide ID AB019224; CP002688; AY139763; BT004537
Gene Name NPR3; At5g45110; K17O22_11
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
AT5G45110 AT5G45110.1 AT5G45110.1
AT5G45110 AT5G45110.2 AT5G45110.2
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
iRefIndexPINAHINTMentha
Protein Expression/Proteomics
Status Reviewed
Details
Family Domain References (PMIDs)
E3 adaptor/Cullin RING/BCR/BTB_3-box BTB_3-box 24840293
Classification
Family E-value Score Start End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB 1.20e-14 55.3 61 133
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB
   S: 2    DvilvvggeeffahkivLaasSsvFyalflmele.esksklmveikd......vqpevfrallkFlYtgklde 67
           D  ++v+g+ + +h+++Laa+S++F++lf++e + ++++k+++++++      v +e+f  +l+++Ytg+l+ 
   Q: 61   DAEIIVDGVPVGVHRCILAARSKFFQDLFKKEKKiSKTEKPKYQLREmlpygaVAHEAFLYFLSYIYTGRLKP 133
           8889******************************9999********778889******************985 PP
   
Organism Arabidopsis thaliana
Functional Description
(View)

Functional Description


     May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Involved in the regulation of basal defense responses against pathogens.
 May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Involved in the regulation of basal defense responses against pathogens.
Protein Sequence
(Fasta)
MATLTEPSSS LSFTSSHFSY GSIGSNHFSS SSASNPEVVS LTKLSSNLEQ LLSNSDCDYS 60
DAEIIVDGVP VGVHRCILAA RSKFFQDLFK KEKKISKTEK PKYQLREMLP YGAVAHEAFL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Ath-006582|E3,BTB_3-box|Arabidopsis thaliana
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CTCTTGTTTC CTCTGTATCT TCCTTCACAT TGAAGCTGTC TCTTTCTTTC ACCATCACTT 60
GCACCTGTTG TGTCCTGTTT GTTCTCAATT TCATCATCAT TTATCCTTTA TATACCTCTC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ath-006582|E3,BTB_3-box|Arabidopsis thaliana
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0040--ANK repeat
KW-0181--Complete proteome
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-0611--Plant defense
KW-1185--Reference proteome
KW-0677--Repeat
KW-0833--Ubl conjugation pathway
Interpro

IPR002110--Ankyrin_rpt
IPR020683--Ankyrin_rpt-contain_dom
IPR000210--BTB/POZ_dom
IPR021094--NPR1/NIM1-like_C
IPR024228--NPR_central_dom
IPR011333--SKP1/BTB/POZ
PROSITE

PS50297--ANK_REP_REGION
PS50088--ANK_REPEAT
PS50097--BTB
Pfam

PF00651--BTB
PF11900--DUF3420
PF12313--NPR1_like_C
SMART

SM00248--ANK
SM00225--BTB
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0019005--C:SCF ubiquitin ligase complex
GO:1901149--F:salicylic acid binding
GO:0031625--F:ubiquitin protein ligase binding
GO:0009816--P:defense response to bacterium, incompatible interaction
GO:0009817--P:defense response to fungus, incompatible interaction
GO:0080185--P:effector dependent induction by symbiont of host immune response
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:2000022--P:regulation of jasmonic acid mediated signaling pathway
GO:0030162--P:regulation of proteolysis
GO:0009627--P:systemic acquired resistance
KEGG ath:AT5G45110
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-001052 Aegilops tauschii 46.96 1.00e-113 403.00
IUUC-Aml-001349 Ailuropoda melanoleuca 35.62 2.00e-06 46.60
IUUC-Atr-003091 Amborella trichopoda 53.90 3.00e-159 554.00
IUUC-Aca-005131 Anolis carolinensis 38.36 2.00e-07 49.70
IUUC-Aly-005725 Arabidopsis lyrata 94.54 0.00e+00 1015.00
IUUC-Bta-012628 Bos taurus 35.62 2.00e-06 46.60
IUUC-Bdi-014820 Brachypodium distachyon 52.10 7.00e-139 486.00
IUUC-Bol-016168 Brassica oleracea 83.87 0.00e+00 917.00
IUUC-Bra-016824 Brassica rapa 80.67 0.00e+00 865.00
IUUC-Cfa-021135 Canis familiaris 35.62 2.00e-06 47.00
IUUC-Dre-028574 Danio rerio 38.36 8.00e-08 51.60
IUUC-Dor-030712 Dipodomys ordii 34.25 2.00e-06 46.20
IUUC-Ete-032755 Echinops telfairi 35.62 1.00e-06 47.40
IUUC-Eeu-035211 Erinaceus europaeus 39.73 1.00e-06 47.80
IUUC-Fca-035796 Felis catus 35.62 2.00e-06 46.60
IUUC-Gmo-038551 Gadus morhua 35.62 5.00e-06 45.40
IUUC-Gac-041350 Gasterosteus aculeatus 35.62 2.00e-06 46.60
IUUC-Gma-042735 Glycine max 63.00 0.00e+00 671.00
IUUC-Hvu-047716 Hordeum vulgare 46.46 1.00e-115 409.00
IUUC-Itr-048458 Ictidomys tridecemlineatus 34.25 3.00e-06 45.80
IUUC-Lpe-051281 Leersia perrieri 51.59 8.00e-133 466.00
IUUC-Meu-056774 Macropus eugenii 36.99 8.00e-07 47.80
IUUC-Mtr-058654 Medicago truncatula 62.34 0.00e+00 669.00
IUUC-Mmr-061098 Microcebus murinus 35.62 2.00e-06 46.60
IUUC-Mdo-062959 Monodelphis domestica 36.99 9.00e-07 47.80
IUUC-Mac-065548 Musa acuminata 55.70 4.00e-153 534.00
IUUC-Mpu-066424 Mustela putorius furo 35.62 2.00e-06 46.60
IUUC-Mlu-067831 Myotis lucifugus 35.62 2.00e-06 47.00
IUUC-Opr-070926 Ochotona princeps 35.62 2.00e-06 47.00
IUUC-Ont-071927 Oreochromis niloticus 36.99 2.00e-07 50.40
IUUC-Oba-075074 Oryza barthii 51.02 8.00e-133 466.00
IUUC-Obr-076350 Oryza brachyantha 54.52 6.00e-117 413.00
IUUC-Ogl-077930 Oryza glaberrima 52.14 2.00e-139 488.00
IUUC-Ogu-078387 Oryza glumaepatula 52.40 2.00e-141 495.00
IUUC-Oin-079463 Oryza indica 51.82 7.00e-139 486.00
IUUC-Olo-080981 Oryza longistaminata 54.27 7.00e-112 396.00
IUUC-Ome-081437 Oryza meridionalis 52.62 1.00e-145 509.00
IUUC-Oni-082237 Oryza nivara 52.40 2.00e-141 495.00
IUUC-Opu-083712 Oryza punctata 50.46 5.00e-131 461.00
IUUC-Oru-084496 Oryza rufipogon 52.04 3.00e-139 488.00
IUUC-Osa-086262 Oryza sativa 52.04 3.00e-139 488.00
IUUC-Ptr-090668 Pan troglodytes 35.62 2.00e-06 46.60
IUUC-Pop-099287 Populus trichocarpa 63.17 0.00e+00 656.00
IUUC-Pca-100466 Procavia capensis 35.62 1.00e-06 47.00
IUUC-Ppe-101348 Prunus persica 60.61 2.00e-178 618.00
IUUC-Pva-102597 Pteropus vampyrus 35.62 1.00e-06 47.00
IUUC-Sha-107275 Sarcophilus harrisii 36.99 9.00e-07 47.80
IUUC-Smo-109065 Selaginella moellendorffii 36.41 8.00e-67 247.00
IUUC-Sit-109849 Setaria italica 51.96 9.00e-147 513.00
IUUC-Sly-111652 Solanum lycopersicum 58.48 3.00e-165 574.00
IUUC-Stu-112546 Solanum tuberosum 58.13 4.00e-165 573.00
IUUC-Sbi-113993 Sorghum bicolor 53.47 4.00e-147 514.00
IUUC-Ssc-115494 Sus scrofa 35.62 2.00e-06 46.60
IUUC-Tca-121013 Theobroma cacao 63.74 0.00e+00 651.00
IUUC-Tae-125381 Triticum aestivum 51.15 7.00e-144 503.00
IUUC-Tur-126023 Triticum urartu 30.14 2.00e-05 42.40
IUUC-Ttr-128342 Tursiops truncatus 35.62 2.00e-06 46.60
IUUC-Vvi-130962 Vitis vinifera 62.82 0.00e+00 646.00
Created Date 25-Jun-2017

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