iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059646

UUCD1 version

UUC-MeG-00115

Ensembl Protein ID

ENSMGAP00000001898.1

UniProt Accession

G1MTW7; G1MTW7_MELGA

Protein Name

Uncharacterized protein

Gene Name

RFWD2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000002304.1	ENSMGAT00000002569.1	ENSMGAP00000001898.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	4.50e-06	26.8	4	41
E3 adaptor/Cullin RING/DCX/DWD	3.80e-23	80.4	337	366

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 2    aiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           +iC++++++  + + CgH f+ +C+++          + rCP C+
   Q: 4    PICFDMIEE-AYMTKCGHSFCYKCIHQS------LEDNNRCPKCN 41
           8******99.888***********9555......999999****7 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 3    tdsvtclaf..sd.tllvsGsdDgtikvWD 29
           +++++c+++     +ll+s+ + gt+ +WD
   Q: 337  NSKISCISWssYHkNLLASSDYEGTVILWD 366
           689******9622599************** PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

FSSPICFDMI EEAYMTKCGH SFCYKCIHQS LEDNNRCPKC NYVVDNIDHL YPNFLVNELI 60
LKQKQRSEEK RFKLDHSVSS TNGHRWQIIQ DLLGTDQDNL DLANVNLMLE LLVQKKKQLE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTTCCAGTC CTATCTGCTT TGATATGATT GAAGAAGCCT ACATGACAAA ATGTGGACAC 60
AGCTTCTGGT AAGATCTTTG TATTGCACAG ATCATCCATC CTGTATGGTG CTTGAGACCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00400--WD40

SMART

SM00184--RING
SM00320--WD40

Gene Ontology

GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0010212--P:response to ionizing radiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000885	Aegilops tauschii	39.81	3.00e-122	432.00
IUUC-Aml-001265	Ailuropoda melanoleuca	97.94	0.00e+00	1157.00
IUUC-Atr-002460	Amborella trichopoda	38.08	2.00e-117	416.00
IUUC-Apl-003796	Anas platyrhynchos	99.83	0.00e+00	1174.00
IUUC-Aca-005078	Anolis carolinensis	97.08	0.00e+00	1125.00
IUUC-Aly-006014	Arabidopsis lyrata	39.45	8.00e-123	434.00
IUUC-Ath-007636	Arabidopsis thaliana	39.29	4.00e-122	431.00
IUUC-Ame-011176	Astyanax mexicanus	96.69	1.00e-69	256.00
IUUC-Bta-012595	Bos taurus	97.94	0.00e+00	1155.00
IUUC-Bdi-014152	Brachypodium distachyon	38.72	6.00e-122	431.00
IUUC-Bol-016380	Brassica oleracea	39.68	3.00e-123	435.00
IUUC-Bra-017690	Brassica rapa	38.97	2.00e-117	416.00
IUUC-Cja-018926	Callithrix jacchus	97.77	0.00e+00	1154.00
IUUC-Cfa-021088	Canis familiaris	97.77	0.00e+00	1157.00
IUUC-Cpo-022442	Cavia porcellus	97.09	0.00e+00	1147.00
IUUC-Cre-022579	Chlamydomonas reinhardtii	33.45	2.00e-33	135.00
IUUC-Csa-024119	Chlorocebus sabaeus	97.94	0.00e+00	1156.00
IUUC-Cho-024883	Choloepus hoffmanni	63.45	2.00e-95	343.00
IUUC-Cin-025375	Ciona intestinalis	55.63	0.00e+00	640.00
IUUC-Cme-027350	Cyanidioschyzon merolae	44.23	4.00e-75	275.00
IUUC-Dre-028453	Danio rerio	87.10	0.00e+00	1019.00
IUUC-Dno-029887	Dasypus novemcinctus	97.43	0.00e+00	1151.00
IUUC-Dor-031110	Dipodomys ordii	78.57	0.00e+00	887.00
IUUC-Ete-033016	Echinops telfairi	82.33	0.00e+00	940.00
IUUC-Eca-034403	Equus caballus	98.44	0.00e+00	1153.00
IUUC-Eeu-034690	Erinaceus europaeus	83.30	0.00e+00	949.00
IUUC-Fca-036475	Felis catus	98.26	0.00e+00	1149.00
IUUC-Fal-037189	Ficedula albicollis	99.14	0.00e+00	1165.00
IUUC-Gmo-039245	Gadus morhua	86.01	0.00e+00	1005.00
IUUC-Gga-040806	Gallus gallus	99.14	0.00e+00	1170.00
IUUC-Gac-042177	Gasterosteus aculeatus	87.54	0.00e+00	1035.00
IUUC-Gma-044187	Glycine max	40.16	3.00e-119	422.00
IUUC-Ggo-044430	Gorilla gorilla	96.88	0.00e+00	867.00
IUUC-Hsa-045853	Homo sapiens	97.60	0.00e+00	1150.00
IUUC-Hvu-047750	Hordeum vulgare	38.27	3.00e-88	320.00
IUUC-Itr-048238	Ictidomys tridecemlineatus	98.75	7.00e-143	498.00
IUUC-Lch-050420	Latimeria chalumnae	90.85	0.00e+00	1064.00
IUUC-Lpe-051219	Leersia perrieri	38.82	1.00e-120	426.00
IUUC-Loc-052728	Lepisosteus oculatus	90.31	0.00e+00	1038.00
IUUC-Laf-053775	Loxodonta africana	97.08	0.00e+00	1159.00
IUUC-Meu-056595	Macropus eugenii	77.46	1.00e-176	612.00
IUUC-Mtr-058555	Medicago truncatula	40.35	5.00e-127	447.00
IUUC-Mmr-060990	Microcebus murinus	97.94	0.00e+00	1156.00
IUUC-Mdo-062287	Monodelphis domestica	97.94	0.00e+00	1156.00
IUUC-Mmu-064097	Mus musculus	97.60	0.00e+00	1153.00
IUUC-Mac-065240	Musa acuminata	40.80	4.00e-128	451.00
IUUC-Mpu-066612	Mustela putorius furo	98.44	0.00e+00	1154.00
IUUC-Mlu-067967	Myotis lucifugus	97.77	0.00e+00	1149.00
IUUC-Nle-069543	Nomascus leucogenys	97.77	0.00e+00	1154.00
IUUC-Opr-070366	Ochotona princeps	82.72	0.00e+00	666.00
IUUC-Ont-071522	Oreochromis niloticus	87.03	0.00e+00	1024.00
IUUC-Oan-073409	Ornithorhynchus anatinus	98.45	0.00e+00	1152.00
IUUC-Ocu-073756	Oryctolagus cuniculus	97.92	0.00e+00	1153.00
IUUC-Oba-075149	Oryza barthii	38.14	2.00e-120	427.00
IUUC-Obr-076563	Oryza brachyantha	38.91	8.00e-121	427.00
IUUC-Ogl-077701	Oryza glaberrima	38.14	8.00e-121	427.00
IUUC-Ogu-078383	Oryza glumaepatula	38.14	8.00e-121	427.00
IUUC-Oin-079965	Oryza indica	36.32	3.00e-109	389.00
IUUC-Olo-080639	Oryza longistaminata	37.99	2.00e-118	419.00
IUUC-Ome-081821	Oryza meridionalis	37.73	1.00e-110	394.00
IUUC-Oni-082622	Oryza nivara	38.14	8.00e-121	427.00
IUUC-Opu-083295	Oryza punctata	38.14	1.00e-120	426.00
IUUC-Oru-084661	Oryza rufipogon	38.14	8.00e-121	427.00
IUUC-Osa-085766	Oryza sativa	38.14	8.00e-121	427.00
IUUC-Ola-086727	Oryzias latipes	87.20	0.00e+00	1043.00
IUUC-Olu-087702	Ostreococcus lucimarinus	43.25	1.00e-65	242.00
IUUC-Oga-088215	Otolemur garnettii	97.95	0.00e+00	1155.00
IUUC-Oar-089880	Ovis aries	97.94	0.00e+00	1158.00
IUUC-Ptr-090597	Pan troglodytes	97.60	0.00e+00	1150.00
IUUC-Pan-091987	Papio anubis	97.94	0.00e+00	1156.00
IUUC-Psi-094033	Pelodiscus sinensis	97.74	0.00e+00	1132.00
IUUC-Pma-094587	Petromyzon marinus	70.47	0.00e+00	771.00
IUUC-Ppa-095256	Physcomitrella patens	37.98	2.00e-125	442.00
IUUC-Pfo-097388	Poecilia formosa	86.13	0.00e+00	1003.00
IUUC-Pab-098029	Pongo abelii	97.60	0.00e+00	1151.00
IUUC-Pop-099319	Populus trichocarpa	38.50	1.00e-123	436.00
IUUC-Pca-100846	Procavia capensis	88.68	0.00e+00	1043.00
IUUC-Ppe-101250	Prunus persica	38.56	9.00e-113	400.00
IUUC-Pva-102407	Pteropus vampyrus	97.60	0.00e+00	1142.00
IUUC-Rno-105312	Rattus norvegicus	97.60	0.00e+00	1151.00
IUUC-Sha-106514	Sarcophilus harrisii	98.92	0.00e+00	773.00
IUUC-Smo-109418	Selaginella moellendorffii	40.16	9.00e-124	437.00
IUUC-Sit-110248	Setaria italica	38.36	2.00e-121	429.00
IUUC-Sly-110964	Solanum lycopersicum	40.38	1.00e-125	443.00
IUUC-Stu-112882	Solanum tuberosum	40.38	1.00e-125	442.00
IUUC-Sar-113230	Sorex araneus	70.69	0.00e+00	773.00
IUUC-Sbi-113962	Sorghum bicolor	36.59	2.00e-116	412.00
IUUC-Ssc-115987	Sus scrofa	96.92	7.00e-159	553.00
IUUC-Tgu-116471	Taeniopygia guttata	98.63	0.00e+00	1164.00
IUUC-Tru-118231	Takifugu rubripes	86.50	0.00e+00	990.00
IUUC-Tsy-119415	Tarsius syrichta	97.24	0.00e+00	1128.00
IUUC-Tni-120893	Tetraodon nigroviridis	86.67	0.00e+00	998.00
IUUC-Tca-121703	Theobroma cacao	41.06	8.00e-124	437.00
IUUC-Tae-125440	Triticum aestivum	40.84	7.00e-128	450.00
IUUC-Tur-126557	Triticum urartu	40.36	3.00e-125	441.00
IUUC-Tbe-127253	Tupaia belangeri	68.44	0.00e+00	763.00
IUUC-Ttr-129100	Tursiops truncatus	97.19	0.00e+00	1097.00
IUUC-Vpa-130613	Vicugna pacos	91.03	0.00e+00	1053.00
IUUC-Vvi-130880	Vitis vinifera	40.70	1.00e-118	419.00
IUUC-Xtr-132033	Xenopus tropicalis	94.68	0.00e+00	1147.00
IUUC-Xma-133421	Xiphophorus maculatus	85.96	0.00e+00	1001.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence