iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052611

Ensembl Protein ID

ENSLOCP00000005405.1

UniProt Accession

W5MAJ6; W5MAJ6_LEPOC

Genbank Protein ID

ENSLOCP00000005405

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01005109

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000004518.1	ENSLOCT00000005413.1	ENSLOCP00000005405.1
ENSLOCG00000004518.1	ENSLOCT00000005433.1	ENSLOCP00000005425.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.30e-68	231.9	77	507

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw...kskkkavsprellkalkkeaeefsgy 87
           Gl NlgNtC+mNS+LQ L+++p++ + l e + ++  ++n++e++ +l+k+l +l+++l     +++ + +   ll++l+++  ++s++
   Q: 77   GLLNLGNTCFMNSLLQGLAACPSFIKWLEEITGRSGLDQNQQERELQLSKTLLHLLKALSsheATEDDVLDAGCLLDVLRSYRWQISSF 165
           9*****************************555555556679*****************977777888999999*************** PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknk..........slisdlFqgqlksqikclecdnvs.sr 165
           e+qDa+E++++l ++leee    ++ +++++++ ++ e++ e++e+k +  +             ++ F+g+l+s+++c++c+++s +r
   Q: 166  EEQDAHELFHVLTSSLEEER--DRQPRVTHLFDIHSLESPPEQNERKVTCRSrgplhplpnpWKSQHPFHGRLTSNMVCKRCEQQSpVR 252
           ********************..6788889999999888888844444444444556666655999************************ PP
   S: 166  eepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekck...............kkqeaekklklkklPevLilhLkRfsf 239
           +++f +lsl++p+    ++ +l++cL++f + e++++   ++ce+c+               ++++  k+lkl klP++L++hL+R ++
   Q: 253  YDSFDSLSLSIPSAPWGHPITLDHCLQHFISSETIKE---VECENCTkiqaggmlngqlmenQRTTFIKQLKLGKLPQCLCIHLQRLTW 338
           ***********************************97...99*****5556666666555555555*********************** PP
   S: 240  seeqksrekinkkvefpleLdlspfcts.............................peekqke......................... 274
           s++ +++ k +++v+f + L+l+ + ++                             p     +                         
   Q: 339  SHQ-GRPLKRQEHVQFAEFLSLDCYKHRapslrsrqpnrtnrpargdspaeaqekssP-----Rgseterlrnnrklvpngacsaliln 421
           996.9999*********99999988877778888887777777777776655555550.....05555566666666666777777777 PP
   S: 275  .................kkkYeLiavvvHsGslssGHYvayvkn.........ekgkWllfdDskVtevkeeevleetgstaYvlfYkr 337
                             + ++L+av+vH+G ++sGH+v+y +           + +Wl ++D++V++++ +evl+   s+aY+lfY+r
   Q: 422  spalssqfpavfdcsssVYLFRLTAVLVHHGDMHSGHFVTYRRGppsprnplaFSSQWLWVSDDSVRKSSLQEVLS---SNAYLLFYER 507
           777777777777777669999***********************8888888877999*******************...********98 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MQCRTEAADK LVREFLRTGS TVSIQEHTQC AQNCSRNKMM KNWGVIGGIA AALAAGVYIL 60
WGPITERKKR KKGMVPGLLN LGNTCFMNSL LQGLAACPSF IKWLEEITGR SGLDQNQQER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATAAAGAACA TTGTATTTGT AACTTAATAG ACTTTGATTA AAATGATGTA CTTTTAATTA 60
CATATCTTGA CATTCTGATT TATTTTTTAT TTCTCTCTCA TTATTCTCCA AAAATAAACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000204	Aegilops tauschii	26.20	2.00e-18	86.70
IUUC-Aml-001733	Ailuropoda melanoleuca	65.23	5.00e-171	593.00
IUUC-Atr-002510	Amborella trichopoda	24.28	1.00e-23	104.00
IUUC-Apl-003645	Anas platyrhynchos	62.50	2.00e-91	328.00
IUUC-Aca-004583	Anolis carolinensis	68.66	5.00e-23	98.60
IUUC-Aly-005754	Arabidopsis lyrata	25.42	5.00e-24	105.00
IUUC-Ath-007622	Arabidopsis thaliana	29.22	2.00e-26	113.00
IUUC-Acl-008136	Aspergillus clavatus	24.54	3.00e-14	73.60
IUUC-Ani-009286	Aspergillus nidulans	27.16	7.00e-12	65.50
IUUC-Ate-010591	Aspergillus terreus	24.24	3.00e-12	67.00
IUUC-Ame-010896	Astyanax mexicanus	70.70	0.00e+00	665.00
IUUC-Bta-012321	Bos taurus	65.42	5.00e-171	594.00
IUUC-Bdi-014795	Brachypodium distachyon	25.67	2.00e-18	87.00
IUUC-Bol-015637	Brassica oleracea	26.95	1.00e-23	104.00
IUUC-Bra-016801	Brassica rapa	25.32	3.00e-25	109.00
IUUC-Cel-018308	Caenorhabditis elegans	28.99	2.00e-38	153.00
IUUC-Cja-018826	Callithrix jacchus	65.74	6.00e-176	610.00
IUUC-Cfa-021206	Canis familiaris	64.55	1.00e-172	598.00
IUUC-Cpo-021343	Cavia porcellus	65.22	7.00e-173	600.00
IUUC-Csa-023419	Chlorocebus sabaeus	66.14	2.00e-176	611.00
IUUC-Cho-024475	Choloepus hoffmanni	61.54	2.00e-92	332.00
IUUC-Cgl-026621	Colletotrichum gloeosporioides	22.18	3.00e-17	84.00
IUUC-Cne-027061	Cryptococcus neoformans	26.36	3.00e-14	73.60
IUUC-Dre-027563	Danio rerio	66.93	0.00e+00	673.00
IUUC-Dno-029929	Dasypus novemcinctus	65.95	2.00e-176	612.00
IUUC-Dor-030166	Dipodomys ordii	56.94	2.00e-139	489.00
IUUC-Dse-031252	Dothistroma septosporum	23.45	3.00e-11	63.50
IUUC-Dme-031627	Drosophila melanogaster	34.75	1.00e-37	150.00
IUUC-Ete-032634	Echinops telfairi	62.61	9.00e-153	533.00
IUUC-Eca-033968	Equus caballus	66.67	6.00e-171	593.00
IUUC-Eeu-035279	Erinaceus europaeus	68.90	1.00e-49	190.00
IUUC-Fca-036525	Felis catus	65.02	7.00e-177	613.00
IUUC-Fal-036606	Ficedula albicollis	64.92	2.00e-138	484.00
IUUC-Fso-038309	Fusarium solani	22.37	2.00e-11	63.90
IUUC-Gmo-038726	Gadus morhua	62.50	5.00e-165	573.00
IUUC-Gga-040718	Gallus gallus	66.67	9.00e-143	499.00
IUUC-Gac-042645	Gasterosteus aculeatus	66.80	4.00e-180	624.00
IUUC-Gma-042890	Glycine max	25.05	4.00e-26	112.00
IUUC-Ggo-045021	Gorilla gorilla	65.44	2.00e-177	615.00
IUUC-Hsa-045832	Homo sapiens	65.44	2.00e-177	615.00
IUUC-Itr-048392	Ictidomys tridecemlineatus	67.85	3.00e-171	594.00
IUUC-Lch-050662	Latimeria chalumnae	67.37	4.00e-178	617.00
IUUC-Lpe-051078	Leersia perrieri	26.92	9.00e-30	124.00
IUUC-Lma-053048	Leptosphaeria maculans	21.12	7.00e-16	79.30
IUUC-Laf-053752	Loxodonta africana	67.08	7.00e-171	593.00
IUUC-Mcc-054892	Macaca mulatta	66.34	8.00e-177	613.00
IUUC-Meu-056673	Macropus eugenii	61.92	5.00e-130	457.00
IUUC-Mor-057143	Magnaporthe oryzae	23.32	6.00e-14	72.80
IUUC-Mtr-057976	Medicago truncatula	26.87	8.00e-36	145.00
IUUC-Mla-058970	Melampsora laricipopulina	25.55	1.00e-21	97.80
IUUC-Mga-059543	Meleagris gallopavo	67.63	9.00e-169	586.00
IUUC-Mmr-061534	Microcebus murinus	64.72	1.00e-176	612.00
IUUC-Mdo-062140	Monodelphis domestica	59.30	2.00e-142	499.00
IUUC-Mmu-063673	Mus musculus	65.33	3.00e-171	594.00
IUUC-Mpu-066328	Mustela putorius furo	65.86	2.00e-173	602.00
IUUC-Mlu-067938	Myotis lucifugus	65.75	2.00e-180	625.00
IUUC-Nfi-068306	Neosartorya fischeri	23.29	2.00e-12	67.80
IUUC-Nle-069426	Nomascus leucogenys	66.07	2.00e-160	558.00
IUUC-Opr-070796	Ochotona princeps	61.57	5.00e-80	291.00
IUUC-Ont-072248	Oreochromis niloticus	69.23	0.00e+00	652.00
IUUC-Oan-072916	Ornithorhynchus anatinus	68.08	2.00e-175	608.00
IUUC-Ocu-074459	Oryctolagus cuniculus	63.92	1.00e-142	499.00
IUUC-Oba-075765	Oryza barthii	27.49	8.00e-32	131.00
IUUC-Obr-076005	Oryza brachyantha	26.87	2.00e-29	123.00
IUUC-Ogl-077916	Oryza glaberrima	28.43	2.00e-34	140.00
IUUC-Ogu-078263	Oryza glumaepatula	27.35	2.00e-32	134.00
IUUC-Oin-080096	Oryza indica	27.90	2.00e-22	100.00
IUUC-Ome-081928	Oryza meridionalis	27.89	9.00e-33	134.00
IUUC-Oni-082424	Oryza nivara	27.49	2.00e-32	133.00
IUUC-Oru-085117	Oryza rufipogon	27.49	2.00e-32	133.00
IUUC-Ola-087429	Oryzias latipes	65.51	6.00e-169	587.00
IUUC-Oga-087981	Otolemur garnettii	65.41	4.00e-176	610.00
IUUC-Oar-089927	Ovis aries	65.42	6.00e-172	597.00
IUUC-Ptr-090878	Pan troglodytes	65.44	2.00e-177	615.00
IUUC-Pan-092698	Papio anubis	66.34	8.00e-177	613.00
IUUC-Psi-093451	Pelodiscus sinensis	68.49	1.00e-180	625.00
IUUC-Ppa-096015	Physcomitrella patens	25.81	2.00e-14	73.90
IUUC-Pfo-096096	Poecilia formosa	67.25	6.00e-178	617.00
IUUC-Pab-098676	Pongo abelii	64.41	1.00e-172	599.00
IUUC-Pca-100418	Procavia capensis	75.00	4.00e-101	361.00
IUUC-Ppe-101898	Prunus persica	25.48	5.00e-26	112.00
IUUC-Pva-103018	Pteropus vampyrus	62.65	3.00e-166	578.00
IUUC-Pgr-103686	Puccinia graminis	23.25	7.00e-13	69.30
IUUC-Ptt-103779	Puccinia triticina	21.46	2.00e-12	68.20
IUUC-Pte-104330	Pyrenophora teres	22.49	5.00e-11	62.80
IUUC-Pyt-104518	Pyrenophora triticirepentis	22.01	3.00e-19	90.50
IUUC-Rno-105708	Rattus norvegicus	64.93	3.00e-171	594.00
IUUC-Sha-106971	Sarcophilus harrisii	67.15	8.00e-177	613.00
IUUC-Ssl-108648	Sclerotinia sclerotiorum	21.36	5.00e-16	79.70
IUUC-Smo-109191	Selaginella moellendorffii	23.53	2.00e-15	76.60
IUUC-Sit-110442	Setaria italica	27.80	5.00e-27	115.00
IUUC-Sly-110928	Solanum lycopersicum	24.80	7.00e-17	81.60
IUUC-Stu-112223	Solanum tuberosum	23.43	3.00e-15	75.90
IUUC-Ssc-116397	Sus scrofa	66.40	5.00e-175	607.00
IUUC-Tgu-117446	Taeniopygia guttata	61.95	3.00e-170	591.00
IUUC-Tru-118268	Takifugu rubripes	64.12	3.00e-164	571.00
IUUC-Tsy-119484	Tarsius syrichta	82.67	1.00e-32	134.00
IUUC-Tni-119735	Tetraodon nigroviridis	65.55	2.00e-145	508.00
IUUC-Tca-121660	Theobroma cacao	25.73	5.00e-28	119.00
IUUC-Tae-125383	Triticum aestivum	28.07	7.00e-28	118.00
IUUC-Tur-126458	Triticum urartu	27.97	2.00e-25	110.00
IUUC-Tbe-127740	Tupaia belangeri	60.04	5.00e-153	534.00
IUUC-Ttr-129273	Tursiops truncatus	63.78	4.00e-169	587.00
IUUC-Vvi-131177	Vitis vinifera	25.58	9.00e-26	111.00
IUUC-Xtr-132374	Xenopus tropicalis	64.14	9.00e-170	589.00
IUUC-Xma-133267	Xiphophorus maculatus	67.98	0.00e+00	649.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence