iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cja-019480

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACFV01146393

Gene Name

OTUB2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000009667.2	ENSCJAT00000018747.2	ENSCJAP00000017725.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/OTU	3.20e-49	167.9	41	230

Active Site

Position(s)	Description	Evidence
48	N/A	{ECO:0000256\|PIRSR:PIRSR013503-1}
51	Nucleophile	{ECO:0000256\|PIRSR:PIRSR013503-1}
224		{ECO:0000256\|PIRSR:PIRSR013503-1}

Domain Profile

DUB/OTU

   S: 2    lilktkgDGnCLlrAvsqs..........................................................llgvfdddslsd 32
           +i+ktkgDGnC++rA+++s                                                          ll+vf+d+s+sd
   Q: 41   AIRKTKGDGNCFYRALGYSylesllgksreivkfkervlqtpndllaagfeehkfrnffnafysvvelvekdssvssLLKVFNDQSTSD 129
           79*************************************************************************************** PP
   S: 33   alveaLreltseylqkesdffsefieekedekefcqklvepeak.geeihifaLaqiLsrpiivvdvdsleskvggillpllfpeeklk 120
           ++v++Lr+lts+++++++dff++fi+e++d+k+fc+++vep+a+ +++i+i+aL+q+Ls++++v++vd++++    +l++++fpe + +
   Q: 130  HIVQFLRLLTSAFIKNRADFFRHFIDEEMDIKDFCTHEVEPMATeCDHIQITALSQALSIALQVEYVDEMDT----ALNHHVFPEGA-T 213
           **********************************************************************95....***********.* PP
   S: 121  kpivLlYrsgHYdaLva 137
           ++++LlY+++HY++L++
   Q: 214  PSVYLLYKTSHYNILYT 230
           ***************97 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MSETSFNLIS EKCDILSILR DHPENRIYRR KIQELSKRFT AIRKTKGDGN CFYRALGYSY 60
LESLLGKSRE IVKFKERVLQ TPNDLLAAGF EEHKFRNFFN AFYSVVELVE KDSSVSSLLK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTTGGTTTG CGGAGCGGTC GGGTGTATTC TCCGCTGCCC CCACGCCCTC GAGGTCTCCG 60
CCACCCGACC CAGCGGCGGA GCCCGCCCGC GCCAGCCGCA GCACCTCCCG CACCGGATCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003323--OTU_dom
IPR030299--OTUB2
IPR016615--Otubain
IPR019400--Peptidase_C65_otubain

PROSITE

PS50802--OTU

Pfam

PF10275--Peptidase_C65

Gene Ontology

GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0035871--P:protein K11-linked deubiquitination
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination

KEGG

cjc:100392228

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002059	Ailuropoda melanoleuca	95.67	1.00e-131	461.00
IUUC-Bta-012766	Bos taurus	94.02	3.00e-130	457.00
IUUC-Cfa-021106	Canis familiaris	95.24	4.00e-131	459.00
IUUC-Cpo-022187	Cavia porcellus	92.70	2.00e-128	451.00
IUUC-Csa-023493	Chlorocebus sabaeus	96.57	3.00e-133	467.00
IUUC-Cho-024411	Choloepus hoffmanni	75.61	7.00e-84	302.00
IUUC-Dno-029346	Dasypus novemcinctus	94.83	1.00e-130	458.00
IUUC-Dor-031012	Dipodomys ordii	94.42	5.00e-131	459.00
IUUC-Ete-032266	Echinops telfairi	86.58	3.00e-118	417.00
IUUC-Eca-033356	Equus caballus	94.81	2.00e-129	454.00
IUUC-Eeu-034775	Erinaceus europaeus	94.37	1.00e-129	454.00
IUUC-Fca-035363	Felis catus	93.94	8.00e-129	452.00
IUUC-Ggo-045023	Gorilla gorilla	96.15	2.00e-133	467.00
IUUC-Hsa-046984	Homo sapiens	96.58	4.00e-134	469.00
IUUC-Itr-048012	Ictidomys tridecemlineatus	94.44	5.00e-132	462.00
IUUC-Lch-050514	Latimeria chalumnae	60.53	2.00e-84	304.00
IUUC-Loc-052003	Lepisosteus oculatus	50.90	1.00e-64	239.00
IUUC-Laf-054382	Loxodonta africana	94.81	1.00e-130	458.00
IUUC-Mcc-055516	Macaca mulatta	96.57	2.00e-133	467.00
IUUC-Meu-056038	Macropus eugenii	87.30	2.00e-98	350.00
IUUC-Mmr-060918	Microcebus murinus	95.73	1.00e-132	465.00
IUUC-Mdo-062638	Monodelphis domestica	88.79	3.00e-123	433.00
IUUC-Mmu-063973	Mus musculus	93.99	2.00e-130	457.00
IUUC-Mpu-066013	Mustela putorius furo	95.24	1.00e-130	458.00
IUUC-Mlu-067509	Myotis lucifugus	92.21	9.00e-126	442.00
IUUC-Nle-069673	Nomascus leucogenys	96.58	4.00e-134	469.00
IUUC-Opr-070761	Ochotona princeps	86.75	1.00e-80	291.00
IUUC-Oan-072922	Ornithorhynchus anatinus	81.66	2.00e-112	397.00
IUUC-Ocu-074643	Oryctolagus cuniculus	93.16	5.00e-130	456.00
IUUC-Oni-082026	Oryza nivara	28.32	2.00e-16	80.50
IUUC-Oru-084761	Oryza rufipogon	28.32	2.00e-16	80.50
IUUC-Ola-086603	Oryzias latipes	45.37	2.00e-52	199.00
IUUC-Oga-088936	Otolemur garnettii	94.42	9.00e-131	458.00
IUUC-Oar-089460	Ovis aries	94.42	1.00e-129	455.00
IUUC-Ptr-090805	Pan troglodytes	96.15	1.00e-133	468.00
IUUC-Pan-091969	Papio anubis	96.58	4.00e-134	469.00
IUUC-Pab-098476	Pongo abelii	96.14	1.00e-132	464.00
IUUC-Pca-100252	Procavia capensis	90.10	4.00e-53	201.00
IUUC-Pva-102204	Pteropus vampyrus	92.74	2.00e-130	457.00
IUUC-Pgr-103552	Puccinia graminis	75.00	2.40e-02	31.60
IUUC-Rno-105062	Rattus norvegicus	94.02	2.00e-131	461.00
IUUC-Sha-106968	Sarcophilus harrisii	88.65	2.00e-121	428.00
IUUC-Sar-113295	Sorex araneus	94.81	3.00e-128	450.00
IUUC-Ssc-115288	Sus scrofa	93.97	1.00e-129	455.00
IUUC-Tni-120440	Tetraodon nigroviridis	40.09	1.00e-43	169.00
IUUC-Tbe-127717	Tupaia belangeri	93.92	1.00e-77	281.00
IUUC-Ttr-128221	Tursiops truncatus	77.59	5.00e-101	360.00
IUUC-Uma-129443	Ustilago maydis	33.65	6.00e-25	107.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence