iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tru-117667

Ensembl Protein ID

ENSTRUP00000000685.1

UniProt Accession

H2RKM2; H2RKM2_TAKRU

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000000305.1	ENSTRUT00000000688.1	ENSTRUP00000000685.1
ENSTRUG00000000305.1	ENSTRUT00000000689.1	ENSTRUP00000000686.1
ENSTRUG00000000305.1	ENSTRUT00000000690.1	ENSTRUP00000000687.1
ENSTRUG00000000305.1	ENSTRUT00000000691.1	ENSTRUP00000000688.1
ENSTRUG00000000305.1	ENSTRUT00000000692.1	ENSTRUP00000000689.1
ENSTRUG00000000305.1	ENSTRUT00000000693.1	ENSTRUP00000000690.1
ENSTRUG00000000305.1	ENSTRUT00000000694.1	ENSTRUP00000000691.1
ENSTRUG00000000305.1	ENSTRUT00000000695.1	ENSTRUP00000000692.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	2.40e-09	38.4	290	337

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCrs 53
           vC +Cg+g++de +l+ C+ C++++H  Cl ++  ++lp+ + w CpkC +
   Q: 290  VCRMCGRGEDDE-KLLLCDGCEDNYHTYCLLPA-LTDLPKGN-WRCPKCVA 337
           8*******9987.6*******************.*******6.******75 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

EFVPPPECPV FEPSWEEFQD PLGYIAKIRP IAEKSGICKI RPPPDWQPPF SVELDSFRFT 60
PRIQRLNELE AETRVKLNYL DRIARFWEIQ ASSLKIPHIE RRILDLFGLS KVVADEGGFE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCAGGGCAA TGGAAGGGGA AGAGTTTGTA CCTCCTCCAG AGTGTCCAGT CTTCGAGCCA 60
TCATGGGAGG AATTTCAGGA TCCTCTGGGC TACATTGCCA AGATTCGTCC AATAGCAGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001606--ARID_dom
IPR003347--JmjC_dom
IPR003349--JmjN
IPR013637--Lys_sp_deMease-like_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR004198--Znf_C5HC2
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51011--ARID
PS51184--JMJC
PS51183--JMJN
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF01388--ARID
PF02373--JmjC
PF02375--JmjN
PF00628--PHD
PF08429--PLU-1
PF02928--zf-C5HC2

SMART

SM00501--BRIGHT
SM00558--JmjC
SM00545--JmjN
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0016706--F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0008270--F:zinc ion binding
GO:0043524--P:negative regulation of neuron apoptotic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001327	Ailuropoda melanoleuca	65.42	0.00e+00	1607.00
IUUC-Aca-004712	Anolis carolinensis	64.22	0.00e+00	1474.00
IUUC-Ani-009139	Aspergillus nidulans	29.17	1.00e-134	474.00
IUUC-Bta-013099	Bos taurus	65.31	0.00e+00	1608.00
IUUC-Bol-015336	Brassica oleracea	34.58	2.00e-14	75.90
IUUC-Cja-018723	Callithrix jacchus	64.19	0.00e+00	1577.00
IUUC-Cfa-020954	Canis familiaris	65.39	0.00e+00	1615.00
IUUC-Cpo-021718	Cavia porcellus	73.40	0.00e+00	1011.00
IUUC-Csa-023946	Chlorocebus sabaeus	65.41	0.00e+00	1629.00
IUUC-Csv-026185	Ciona savignyi	45.04	0.00e+00	1087.00
IUUC-Dre-028238	Danio rerio	67.46	0.00e+00	2054.00
IUUC-Dno-029435	Dasypus novemcinctus	65.36	0.00e+00	1602.00
IUUC-Dor-030226	Dipodomys ordii	62.06	0.00e+00	1208.00
IUUC-Dme-032021	Drosophila melanogaster	44.69	0.00e+00	1031.00
IUUC-Eca-033834	Equus caballus	64.96	0.00e+00	1614.00
IUUC-Eeu-034692	Erinaceus europaeus	66.17	0.00e+00	1249.00
IUUC-Fca-035766	Felis catus	61.55	0.00e+00	1488.00
IUUC-Gmo-039140	Gadus morhua	76.66	0.00e+00	2013.00
IUUC-Gac-041825	Gasterosteus aculeatus	82.36	0.00e+00	2150.00
IUUC-Ggo-045492	Gorilla gorilla	65.41	0.00e+00	1632.00
IUUC-Hsa-046737	Homo sapiens	65.16	0.00e+00	1627.00
IUUC-Hvu-047583	Hordeum vulgare	41.77	8.00e-15	76.30
IUUC-Itr-048348	Ictidomys tridecemlineatus	65.36	0.00e+00	1635.00
IUUC-Lch-050517	Latimeria chalumnae	62.59	0.00e+00	1660.00
IUUC-Mcc-055740	Macaca mulatta	65.41	0.00e+00	1632.00
IUUC-Meu-056643	Macropus eugenii	63.46	0.00e+00	1518.00
IUUC-Mmr-061032	Microcebus murinus	65.43	0.00e+00	1621.00
IUUC-Mdo-062754	Monodelphis domestica	58.77	0.00e+00	1346.00
IUUC-Mmu-063943	Mus musculus	60.52	0.00e+00	1638.00
IUUC-Mac-065069	Musa acuminata	36.94	4.00e-09	58.50
IUUC-Mpu-066800	Mustela putorius furo	64.96	0.00e+00	1615.00
IUUC-Mlu-067109	Myotis lucifugus	65.16	0.00e+00	1612.00
IUUC-Nfi-068430	Neosartorya fischeri	30.06	1.00e-145	511.00
IUUC-Nle-069569	Nomascus leucogenys	65.26	0.00e+00	1631.00
IUUC-Opr-071002	Ochotona princeps	49.13	0.00e+00	1208.00
IUUC-Ont-072274	Oreochromis niloticus	78.42	0.00e+00	2212.00
IUUC-Oan-073160	Ornithorhynchus anatinus	64.68	0.00e+00	1566.00
IUUC-Ocu-074440	Oryctolagus cuniculus	64.91	0.00e+00	1611.00
IUUC-Obr-076296	Oryza brachyantha	32.98	5.00e-89	323.00
IUUC-Ogl-077886	Oryza glaberrima	37.86	3.00e-16	80.90
IUUC-Oin-079273	Oryza indica	50.00	6.00e-14	70.10
IUUC-Olo-080668	Oryza longistaminata	37.86	6.00e-16	80.90
IUUC-Ome-081764	Oryza meridionalis	28.48	4.00e-97	350.00
IUUC-Oni-083012	Oryza nivara	26.98	9.00e-80	292.00
IUUC-Oru-084630	Oryza rufipogon	27.18	1.00e-79	292.00
IUUC-Osa-085487	Oryza sativa	37.86	3.00e-16	80.90
IUUC-Ola-087059	Oryzias latipes	79.94	0.00e+00	2157.00
IUUC-Oga-088191	Otolemur garnettii	61.04	0.00e+00	1635.00
IUUC-Oar-090027	Ovis aries	65.31	0.00e+00	1607.00
IUUC-Ptr-091415	Pan troglodytes	63.49	0.00e+00	1583.00
IUUC-Pan-091829	Papio anubis	65.41	0.00e+00	1633.00
IUUC-Pfo-096645	Poecilia formosa	77.72	0.00e+00	1768.00
IUUC-Pab-097582	Pongo abelii	63.99	0.00e+00	1557.00
IUUC-Pca-100446	Procavia capensis	60.16	0.00e+00	1619.00
IUUC-Rno-105359	Rattus norvegicus	58.31	0.00e+00	1629.00
IUUC-Sha-106769	Sarcophilus harrisii	64.39	0.00e+00	1494.00
IUUC-Sit-110534	Setaria italica	30.36	2.00e-109	391.00
IUUC-Sre-115161	Sporisorium reilianum	30.53	2.00e-126	447.00
IUUC-Ssc-116354	Sus scrofa	65.24	0.00e+00	1627.00
IUUC-Tsy-119237	Tarsius syrichta	51.67	0.00e+00	1236.00
IUUC-Tni-119920	Tetraodon nigroviridis	82.90	0.00e+00	2308.00
IUUC-Tbe-128040	Tupaia belangeri	75.54	0.00e+00	860.00
IUUC-Ttr-128979	Tursiops truncatus	65.11	0.00e+00	1617.00
IUUC-Uma-129590	Ustilago maydis	31.19	4.00e-125	443.00
IUUC-Vpa-130433	Vicugna pacos	66.53	0.00e+00	1215.00
IUUC-Xtr-132324	Xenopus tropicalis	61.25	0.00e+00	1538.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence