iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Rno-105268

Ensembl Protein ID

ENSRNOP00000063689.2

UniProt Accession

D3ZVD8; F1LSE3; D3ZVD8_RAT

Genbank Protein ID

ENSRNOP00000063689

Protein Name

Histone deacetylase 6

Genbank Nucleotide ID

AABR07073519

Gene Name

Hdac6; LOC100911205

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000047281.1	ENSRNOT00000064924.2	ENSRNOP00000063689.2

Annotation

Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/ZnF/ZnF_UBP	91.33	0.00e+00	2022.00	IUUC-Mmu-064418

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MTSTGQDSST RQRKSRHNPQ SPLQDSSATL KRGGKKGAVP HSSPNLAEVK KKGKMKKLSQ 60
PAEEDLIVGL QGLDLNSETR VPVGTGLVFD EQLNDFHCLW DDSFPENPER LHAIKEQLIL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACCTCCA CCGGCCAAGA TTCTTCTACC AGGCAGCGAA AGAGTAGGCA CAATCCCCAA 60
TCGCCCCTTC AGGACTCCAG CGCCACCTTG GTGAGGCCCC AGACCAGCCC TGCTGGGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR000286--His_deacetylse
IPR023801--His_deacetylse_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50271--ZF_UBP

Pfam

PF00850--Hist_deacetyl
PF02148--zf-UBP

PRINTS

PR01270--HDASUPER

SMART

SM00290--ZnF_UBP

Gene Ontology

GO:0030424--C:axon
GO:1904115--C:axon cytoplasm
GO:0005813--C:centrosome
GO:0016787--F:hydrolase activity
GO:0008270--F:zinc ion binding
GO:0019896--P:axonal transport of mitochondrion
GO:0034599--P:cellular response to oxidative stress
GO:0071374--P:cellular response to parathyroid hormone stimulus
GO:0048843--P:negative regulation of axon extension involved in axon guidance
GO:0010977--P:negative regulation of neuron projection development
GO:1901984--P:negative regulation of protein acetylation
GO:0030182--P:neuron differentiation
GO:1904056--P:positive regulation of cholangiocyte proliferation
GO:0050775--P:positive regulation of dendrite morphogenesis
GO:1903223--P:positive regulation of oxidative stress-induced neuron death
GO:0051968--P:positive regulation of synaptic transmission, glutamatergic
GO:0090044--P:positive regulation of tubulin deacetylation
GO:0070507--P:regulation of microtubule cytoskeleton organization
GO:0010821--P:regulation of mitochondrion organization
GO:0001932--P:regulation of protein phosphorylation
GO:0001975--P:response to amphetamine
GO:0051412--P:response to corticosterone
GO:0071548--P:response to dexamethasone
GO:0035902--P:response to immobilization stress

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Acl-008187	Aspergillus clavatus	45.45	1.00e-87	318.00
IUUC-Bci-013789	Botrytis cinerea	40.45	1.00e-78	287.00
IUUC-Gma-043738	Glycine max	47.66	3.00e-89	323.00
IUUC-Hvu-047285	Hordeum vulgare	46.63	4.00e-85	307.00
IUUC-Kpa-049281	Komagataella pastoris	41.64	1.00e-86	314.00
IUUC-Mmu-064418	Mus musculus	92.02	0.00e+00	2078.00
IUUC-Oan-072911	Ornithorhynchus anatinus	70.40	2.00e-107	384.00
IUUC-Ogu-078370	Oryza glumaepatula	44.60	6.00e-87	315.00
IUUC-Oni-082031	Oryza nivara	44.69	1.00e-86	314.00
IUUC-Osa-085447	Oryza sativa	44.69	8.00e-87	315.00
IUUC-Ppe-101644	Prunus persica	45.40	3.00e-91	329.00
IUUC-Tsy-118807	Tarsius syrichta	63.02	0.00e+00	821.00
IUUC-Tme-127027	Tuber melanosporum	41.35	1.00e-75	277.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence