iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Sce-106134

UUCD1 version

UUC-SaC-00045

Ensembl Protein ID

YDR131C

UniProt Accession

Q03899; D6VSB7; YD131_YEAST

Genbank Protein ID

CAA88212.1; DAA11977.1

Protein Name

F-box protein YDR131C

Genbank Nucleotide ID

Z48179; BK006938

Gene Name

YDR131C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
YDR131C	YDR131C	YDR131C

Annotation

mRNA Expression
GEO	FFGED
Protein-protein Interaction
IID	iRefIndex	HINT	Mentha
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 adaptor/Cullin RING/SCF/F-box	F-box	14747994

Classification

Family	E-value	Score	Start	End
E3 adaptor/Cullin RING/SCF/F-box	0.061	11.8	2	36

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/SCF/F-box

   S: 103  ldrlpeeilveilklldkeellraarvcrrwqela 137
           +d+lp+ei  +i  ++++e++++++ vc+r +e +
   Q: 2    FDKLPYEIFKQIAWRIPQEDKISLTYVCKRSYESI 36
           689***************************99655 PP

Organism

Saccharomyces cerevisiae

Functional Description
(View)

Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins (By similarity).

Protein Sequence
(Fasta)

MFDKLPYEIF KQIAWRIPQE DKISLTYVCK RSYESIIPFI YQNLFLNETY HINGDYDNSF 60
GTCYWSVLNF HYIDEDDSNT KNDMSNRRLA KVKFSYFERT LAESPKRLCP LINRIRCTWH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTTGATA AGTTACCTTA TGAGATTTTT AAACAAATTG CCTGGAGAAT TCCGCAGGAA 60
GATAAAATTT CGTTAACATA TGTATGCAAA AGATCCTATG AATCAATTAT ACCTTTCATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0926--Vacuole

Interpro

IPR001810--F-box_dom
IPR032675--L_dom-like

PROSITE

PS50181--FBOX

Gene Ontology

GO:0019005--C:SCF ubiquitin ligase complex
GO:0005773--C:vacuole
GO:0030674--F:protein binding, bridging
GO:0016567--P:protein ubiquitination
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

KEGG

sce:YDR131C

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000647	Aegilops tauschii	44.00	2.50e-01	28.10
IUUC-Atr-003166	Amborella trichopoda	30.88	7.00e-03	31.60
IUUC-Aca-004359	Anolis carolinensis	34.48	6.80e-02	30.00
IUUC-Acl-008341	Aspergillus clavatus	36.00	3.50e-02	32.00
IUUC-Afl-008492	Aspergillus flavus	35.09	4.50e-02	30.40
IUUC-Ani-009193	Aspergillus nidulans	50.00	3.40e-02	31.20
IUUC-Ate-010552	Aspergillus terreus	35.14	2.60e+00	25.80
IUUC-Ame-010894	Astyanax mexicanus	23.91	8.40e-01	27.30
IUUC-Bci-013976	Botrytis cinerea	33.33	1.10e-02	33.10
IUUC-Bdi-014386	Brachypodium distachyon	31.94	5.00e-03	33.90
IUUC-Bra-016807	Brassica rapa	53.85	4.00e-03	31.20
IUUC-Cgl-026638	Colletotrichum gloeosporioides	42.42	2.50e-01	29.30
IUUC-Dse-031301	Dothistroma septosporum	22.83	1.80e-02	33.50
IUUC-Dme-031948	Drosophila melanogaster	38.64	2.70e-02	31.60
IUUC-Ete-032951	Echinops telfairi	36.54	3.00e-03	34.30
IUUC-Fox-037948	Fusarium oxysporum	26.62	6.00e-03	33.50
IUUC-Ggr-039759	Gaeumannomyces graminis	22.92	3.40e-02	30.80
IUUC-Gga-041272	Gallus gallus	28.57	5.50e-02	31.20
IUUC-Gac-042153	Gasterosteus aculeatus	23.91	2.60e-01	28.50
IUUC-Hvu-047181	Hordeum vulgare	39.29	4.00e-03	33.50
IUUC-Kpa-049099	Komagataella pastoris	36.17	6.00e-04	37.40
IUUC-Lpe-051356	Leersia perrieri	35.82	3.90e-02	32.70
IUUC-Mtr-058739	Medicago truncatula	23.89	1.50e-02	32.30
IUUC-Mga-059392	Meleagris gallopavo	31.71	1.40e-01	28.90
IUUC-Oba-075526	Oryza barthii	28.77	7.00e-03	33.50
IUUC-Obr-076573	Oryza brachyantha	22.03	1.10e-01	28.90
IUUC-Ogl-077037	Oryza glaberrima	28.77	8.00e-03	32.70
IUUC-Ogu-078568	Oryza glumaepatula	28.77	7.00e-03	33.50
IUUC-Oin-079412	Oryza indica	28.77	8.00e-03	32.70
IUUC-Olo-080439	Oryza longistaminata	28.77	6.00e-03	32.70
IUUC-Ome-081365	Oryza meridionalis	28.77	8.00e-03	32.70
IUUC-Oni-083060	Oryza nivara	25.25	5.00e-03	35.00
IUUC-Opu-083661	Oryza punctata	28.77	8.00e-03	33.10
IUUC-Oru-084874	Oryza rufipogon	38.75	4.00e-03	34.70
IUUC-Osa-086232	Oryza sativa	28.77	8.00e-03	32.70
IUUC-Ola-086826	Oryzias latipes	39.29	1.70e-02	32.00
IUUC-Psi-092981	Pelodiscus sinensis	23.91	9.40e-01	26.90
IUUC-Pno-095128	Phaeosphaeria nodorum	29.69	4.00e-03	33.90
IUUC-Spo-108379	Schizosaccharomyces pombe	36.67	1.10e-01	30.00
IUUC-Ssl-108485	Sclerotinia sclerotiorum	36.67	1.50e-01	29.30
IUUC-Smo-109089	Selaginella moellendorffii	28.99	1.00e-03	35.00
IUUC-Sit-109714	Setaria italica	31.94	5.00e-03	33.90
IUUC-Sly-111545	Solanum lycopersicum	30.77	4.00e-03	34.30
IUUC-Stu-112042	Solanum tuberosum	30.77	4.00e-03	34.30
IUUC-Sbi-114732	Sorghum bicolor	38.46	1.90e+00	25.40
IUUC-Sre-115007	Sporisorium reilianum	28.17	1.60e-01	29.30
IUUC-Tni-120579	Tetraodon nigroviridis	39.29	1.30e-02	32.30
IUUC-Tae-124156	Triticum aestivum	30.16	5.00e-04	37.00
IUUC-Tur-126734	Triticum urartu	30.16	3.00e-04	36.20
IUUC-Tme-126954	Tuber melanosporum	36.96	8.00e-05	39.70
IUUC-Vpa-130635	Vicugna pacos	29.58	2.20e-02	30.80
IUUC-Vvi-130898	Vitis vinifera	43.48	1.90e+00	25.80
IUUC-Xtr-132519	Xenopus tropicalis	34.48	7.40e-02	30.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence