iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-068046

Ensembl Protein ID

ENSMLUP00000007232.2

UniProt Accession

G1PAC6; G1PAC6_MYOLU

Genbank Protein ID

ENSMLUP00000007232

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02030398

Gene Name

AURKA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000007925.2	ENSMLUT00000007920.2	ENSMLUP00000007232.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	90.18	0.00e+00	716.00	IUUC-Hsa-046968

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

SGIMDKSKEN GISGLVKTTI PSGDGPKRVL VTQQFPSQYP LPANSGQAQR VLCPSNSSQQ 60
VPSKAQKLVS SHKPVLNLKQ KQLQATSGPC PVSRPLNNTQ KSEQPQPPAP GKNSEKEVAS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCAGGCATCA TGGACAAATC TAAAGAAAAC GGCATTTCAG GGCTGGTTAA GGTAAACTGA 60
ATAATCTGTA ACCTCAGTCA CGTTTATAAA ACCCAAATGG AGATCGGTCT TCTATCTGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR030616--Aur
IPR030611--AURKA
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0043203--C:axon hillock
GO:0005829--C:cytosol
GO:0042585--C:germinal vesicle
GO:0072687--C:meiotic spindle
GO:0072686--C:mitotic spindle
GO:0048471--C:perinuclear region of cytoplasm
GO:0045120--C:pronucleus
GO:0005876--C:spindle microtubule
GO:0031616--C:spindle pole centrosome
GO:0005524--F:ATP binding
GO:0035174--F:histone serine kinase activity
GO:0009948--P:anterior/posterior axis specification
GO:0051642--P:centrosome localization
GO:0097421--P:liver regeneration
GO:0007100--P:mitotic centrosome separation
GO:0007052--P:mitotic spindle organization
GO:0043066--P:negative regulation of apoptotic process
GO:0032091--P:negative regulation of protein binding
GO:1990138--P:neuron projection extension
GO:1900195--P:positive regulation of oocyte maturation
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0071539--P:protein localization to centrosome
GO:0031647--P:regulation of protein stability
GO:0009611--P:response to wounding
GO:0007057--P:spindle assembly involved in female meiosis I

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000930	Aegilops tauschii	62.68	2.00e-103	368.00
IUUC-Aml-001426	Ailuropoda melanoleuca	90.77	0.00e+00	728.00
IUUC-Atr-002453	Amborella trichopoda	67.17	4.00e-107	380.00
IUUC-Apl-003626	Anas platyrhynchos	68.70	6.00e-150	523.00
IUUC-Aca-004602	Anolis carolinensis	65.69	5.00e-147	514.00
IUUC-Aly-005878	Arabidopsis lyrata	65.17	4.00e-105	374.00
IUUC-Ath-007117	Arabidopsis thaliana	65.92	7.00e-106	376.00
IUUC-Acl-008199	Aspergillus clavatus	57.30	3.00e-88	318.00
IUUC-Afl-008419	Aspergillus flavus	58.82	2.00e-87	316.00
IUUC-Afu-008751	Aspergillus fumigatus	53.56	1.00e-88	320.00
IUUC-Ani-009181	Aspergillus nidulans	53.20	9.00e-92	330.00
IUUC-Ang-009787	Aspergillus niger	53.56	1.00e-88	319.00
IUUC-Aor-009980	Aspergillus oryzae	58.82	2.00e-87	316.00
IUUC-Ate-010286	Aspergillus terreus	56.93	9.00e-88	317.00
IUUC-Ame-010849	Astyanax mexicanus	58.48	8.00e-127	446.00
IUUC-Bgr-012110	Blumeria graminis	50.87	1.00e-88	319.00
IUUC-Bta-013474	Bos taurus	87.86	0.00e+00	697.00
IUUC-Bci-013756	Botrytis cinerea	52.81	3.00e-94	338.00
IUUC-Bdi-014257	Brachypodium distachyon	63.38	6.00e-105	373.00
IUUC-Bol-016310	Brassica oleracea	61.70	1.00e-102	365.00
IUUC-Bra-017438	Brassica rapa	63.24	7.00e-104	370.00
IUUC-Cel-018157	Caenorhabditis elegans	62.88	2.00e-102	365.00
IUUC-Cja-019282	Callithrix jacchus	88.63	0.00e+00	684.00
IUUC-Cfa-020162	Canis familiaris	89.74	0.00e+00	722.00
IUUC-Cpo-021764	Cavia porcellus	84.32	0.00e+00	648.00
IUUC-Cre-022827	Chlamydomonas reinhardtii	67.42	3.00e-108	384.00
IUUC-Csa-023694	Chlorocebus sabaeus	88.63	0.00e+00	645.00
IUUC-Cho-024350	Choloepus hoffmanni	93.37	9.00e-109	385.00
IUUC-Cin-025542	Ciona intestinalis	72.20	4.00e-116	410.00
IUUC-Csv-025873	Ciona savignyi	67.83	6.00e-118	416.00
IUUC-Cgl-026632	Colletotrichum gloeosporioides	47.84	3.00e-83	301.00
IUUC-Cne-026928	Cryptococcus neoformans	61.87	2.00e-95	342.00
IUUC-Cme-027336	Cyanidioschyzon merolae	73.38	8.00e-120	423.00
IUUC-Dre-028198	Danio rerio	62.20	1.00e-128	452.00
IUUC-Dno-029928	Dasypus novemcinctus	86.56	0.00e+00	653.00
IUUC-Dor-030238	Dipodomys ordii	77.78	3.00e-173	600.00
IUUC-Dse-031266	Dothistroma septosporum	57.14	1.00e-93	336.00
IUUC-Dme-032007	Drosophila melanogaster	62.84	5.00e-102	364.00
IUUC-Ete-032911	Echinops telfairi	66.67	5.00e-132	464.00
IUUC-Eca-033749	Equus caballus	90.70	0.00e+00	716.00
IUUC-Eeu-035170	Erinaceus europaeus	86.34	0.00e+00	681.00
IUUC-Fca-035498	Felis catus	91.42	0.00e+00	704.00
IUUC-Fal-037397	Ficedula albicollis	64.41	1.00e-145	509.00
IUUC-Fox-037747	Fusarium oxysporum	51.86	1.00e-91	330.00
IUUC-Fso-038429	Fusarium solani	53.27	4.00e-92	331.00
IUUC-Gmo-039378	Gadus morhua	75.00	7.00e-123	433.00
IUUC-Ggr-039939	Gaeumannomyces graminis	60.89	2.00e-95	342.00
IUUC-Gga-040187	Gallus gallus	71.14	1.00e-150	525.00
IUUC-Gac-042223	Gasterosteus aculeatus	59.64	7.00e-129	453.00
IUUC-Gma-042870	Glycine max	64.23	2.00e-99	355.00
IUUC-Ggo-045617	Gorilla gorilla	89.92	0.00e+00	713.00
IUUC-Hsa-046968	Homo sapiens	90.18	0.00e+00	715.00
IUUC-Hvu-047072	Hordeum vulgare	54.02	3.00e-80	291.00
IUUC-Itr-048233	Ictidomys tridecemlineatus	76.23	9.00e-169	586.00
IUUC-Kpa-049093	Komagataella pastoris	55.94	6.00e-77	280.00
IUUC-Lch-050346	Latimeria chalumnae	68.46	2.00e-148	518.00
IUUC-Lpe-051466	Leersia perrieri	64.73	4.00e-105	374.00
IUUC-Lma-053006	Leptosphaeria maculans	58.94	3.00e-90	325.00
IUUC-Laf-053422	Loxodonta africana	87.60	0.00e+00	692.00
IUUC-Mcc-055245	Macaca mulatta	88.63	0.00e+00	642.00
IUUC-Mor-056952	Magnaporthe oryzae	59.16	2.00e-91	329.00
IUUC-Mpo-057605	Magnaporthe poae	60.07	2.00e-96	345.00
IUUC-Mtr-057726	Medicago truncatula	62.86	9.00e-105	372.00
IUUC-Mla-059174	Melampsora laricipopulina	63.32	7.00e-99	354.00
IUUC-Mga-059562	Meleagris gallopavo	61.08	2.00e-115	409.00
IUUC-Mvi-060305	Microbotryum violaceum	61.22	1.00e-92	333.00
IUUC-Mmr-061588	Microcebus murinus	86.79	0.00e+00	694.00
IUUC-Mdo-061914	Monodelphis domestica	78.61	1.00e-176	612.00
IUUC-Mmu-063288	Mus musculus	82.78	0.00e+00	637.00
IUUC-Mac-064969	Musa acuminata	64.44	3.00e-106	377.00
IUUC-Mpu-066855	Mustela putorius furo	88.89	0.00e+00	708.00
IUUC-Nfi-068527	Neosartorya fischeri	59.61	3.00e-88	318.00
IUUC-Ncr-068678	Neurospora crassa	61.22	1.00e-93	337.00
IUUC-Nle-069848	Nomascus leucogenys	89.66	0.00e+00	710.00
IUUC-Opr-070589	Ochotona princeps	80.83	3.00e-174	604.00
IUUC-Ont-071733	Oreochromis niloticus	61.25	4.00e-121	427.00
IUUC-Oan-073399	Ornithorhynchus anatinus	82.89	4.00e-150	523.00
IUUC-Ocu-074063	Oryctolagus cuniculus	84.72	0.00e+00	672.00
IUUC-Oba-075264	Oryza barthii	63.48	2.00e-104	371.00
IUUC-Obr-076048	Oryza brachyantha	65.66	6.00e-104	370.00
IUUC-Ogl-077637	Oryza glaberrima	66.54	7.00e-104	370.00
IUUC-Ogu-078830	Oryza glumaepatula	63.48	1.00e-104	372.00
IUUC-Oin-079150	Oryza indica	63.48	1.00e-104	372.00
IUUC-Olo-080398	Oryza longistaminata	57.26	4.00e-82	297.00
IUUC-Ome-081544	Oryza meridionalis	55.85	2.00e-91	328.00
IUUC-Oni-082250	Oryza nivara	63.48	1.00e-104	372.00
IUUC-Opu-083638	Oryza punctata	64.08	6.00e-105	373.00
IUUC-Oru-084981	Oryza rufipogon	63.48	8.00e-105	373.00
IUUC-Osa-085961	Oryza sativa	63.48	8.00e-105	373.00
IUUC-Olu-087880	Ostreococcus lucimarinus	69.73	2.00e-111	395.00
IUUC-Oga-088891	Otolemur garnettii	87.40	0.00e+00	702.00
IUUC-Oar-090021	Ovis aries	87.66	0.00e+00	681.00
IUUC-Ptr-091458	Pan troglodytes	90.44	0.00e+00	715.00
IUUC-Pan-092546	Papio anubis	88.11	0.00e+00	641.00
IUUC-Psi-093280	Pelodiscus sinensis	72.21	1.00e-161	562.00
IUUC-Pma-094298	Petromyzon marinus	76.34	2.00e-119	421.00
IUUC-Pno-094847	Phaeosphaeria nodorum	59.40	4.00e-90	324.00
IUUC-Ppa-095855	Physcomitrella patens	62.77	2.00e-107	382.00
IUUC-Pfo-096428	Poecilia formosa	60.81	4.00e-126	444.00
IUUC-Pab-098696	Pongo abelii	89.18	0.00e+00	695.00
IUUC-Pop-099405	Populus trichocarpa	64.62	1.00e-105	376.00
IUUC-Pca-100740	Procavia capensis	81.91	0.00e+00	648.00
IUUC-Ppe-101854	Prunus persica	63.48	4.00e-106	377.00
IUUC-Pva-103212	Pteropus vampyrus	88.89	0.00e+00	707.00
IUUC-Pgr-103474	Puccinia graminis	62.50	5.00e-98	350.00
IUUC-Ptt-103933	Puccinia triticina	48.65	2.00e-61	229.00
IUUC-Pte-104089	Pyrenophora teres	59.02	4.00e-90	324.00
IUUC-Pyt-104555	Pyrenophora triticirepentis	59.02	4.00e-90	325.00
IUUC-Rno-105057	Rattus norvegicus	84.75	0.00e+00	657.00
IUUC-Sha-107137	Sarcophilus harrisii	79.74	3.00e-179	621.00
IUUC-Sja-107767	Schizosaccharomyces japonicus	60.29	3.00e-99	354.00
IUUC-Spo-108078	Schizosaccharomyces pombe	63.85	4.00e-102	364.00
IUUC-Smo-109288	Selaginella moellendorffii	66.79	2.00e-107	381.00
IUUC-Sit-110246	Setaria italica	65.33	1.00e-104	372.00
IUUC-Sly-111379	Solanum lycopersicum	65.20	2.00e-106	378.00
IUUC-Stu-112777	Solanum tuberosum	62.28	3.00e-105	374.00
IUUC-Sbi-114325	Sorghum bicolor	64.96	1.00e-104	372.00
IUUC-Sre-115203	Sporisorium reilianum	57.89	2.00e-79	290.00
IUUC-Ssc-115361	Sus scrofa	90.18	0.00e+00	716.00
IUUC-Tgu-116967	Taeniopygia guttata	69.45	5.00e-146	510.00
IUUC-Tru-117570	Takifugu rubripes	63.47	1.00e-133	469.00
IUUC-Tsy-119280	Tarsius syrichta	66.15	1.00e-130	459.00
IUUC-Tni-120721	Tetraodon nigroviridis	62.37	2.00e-133	468.00
IUUC-Tca-121494	Theobroma cacao	64.03	7.00e-105	373.00
IUUC-Tre-121869	Trichoderma reesei	54.89	1.00e-94	339.00
IUUC-Tvi-122510	Trichoderma virens	58.48	8.00e-92	330.00
IUUC-Tae-123071	Triticum aestivum	62.68	2.00e-103	368.00
IUUC-Tur-126240	Triticum urartu	62.68	6.00e-103	367.00
IUUC-Tme-126921	Tuber melanosporum	62.93	9.00e-97	347.00
IUUC-Tbe-127872	Tupaia belangeri	83.20	6.00e-179	619.00
IUUC-Ttr-129134	Tursiops truncatus	89.41	0.00e+00	685.00
IUUC-Uma-129412	Ustilago maydis	58.49	3.00e-78	285.00
IUUC-Vda-130003	Verticillium dahliae	54.15	1.00e-92	333.00
IUUC-Vvi-131272	Vitis vinifera	66.04	1.00e-105	375.00
IUUC-Xtr-132019	Xenopus tropicalis	65.43	2.00e-151	528.00
IUUC-Xma-134203	Xiphophorus maculatus	60.88	3.00e-131	461.00
IUUC-Yli-134503	Yarrowia lipolytica	54.62	1.00e-86	312.00
IUUC-Zma-135232	Zea mays	65.20	2.00e-104	371.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence