iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Ath-007239

UUCD1 version

UUC-ArT-01112

Ensembl Protein ID

AT3G60220.1

UniProt Accession

Q9LY41; Q4TU21; Q9SPV6; Q9ZT40; ATL4_ARATH

Genbank Protein ID

AAD33582.1; AAY57601.1; CAB87859.1; AEE80025.1; ABI49480.1; AAC69858.1

Protein Name

E3 ubiquitin-protein ligase ATL4; Protein ARABIDOPSIS TOXICOS EN LEVADURA 4; RING-H2 finger X1a; RING-H2 zinc finger protein ATL4; RING-H2 zinc finger protein RHX1a; RING-type E3 ubiquitin transferase ATL4

Genbank Nucleotide ID

AF132014; DQ059115; AL163852; CP002686; BT028933; AF079184

Gene Name

ATL4; RHX1A; At3g60220; F27H5_10

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT3G60220	AT3G60220.1	AT3G60220.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
Protein-protein Interaction
HINT	Mentha
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.10e-07	31.7	117	159

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..kdgplvlp.CgHvfhadClqkwpglknssskefrCPlCr 46
           Ca+Cl+ f  +d++++lp C H+fhadC+  w         +++CPlCr
   Q: 117  CAVCLSKFepEDQLRLLPlCCHAFHADCIDIW------LVSNQTCPLCR 159
           ******9988777*******************......999*******8 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

E3 ubiquitin-protein ligase able to catalyze polyubiquitination with ubiquitin-conjugating enzyme E2 UBC8 in vitro.

Protein Sequence
(Fasta)

MESLINPSHG GGNYDSHSSS LDSLKPSVLV IILILLMTLL ISVSICFLLR CLNRCSHRSV 60
LPLSSSSSVA TVTSDSRRFS GHRVSPETER SSVLDSLPIF KFSSVTRRSS SMNSGDCAVC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAAATGTTT TACATAAATA CATGTCACAA CTCTCCTCAA TTTATGACCT TAACAAAATG 60
CAAAAATACC TTAAGAAGAT AGTGGACAAA ATTGAAAGCA AAGTGAAAAG CCAATTGATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0016567--P:protein ubiquitination

KEGG

ath:AT3G60220

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-002666	Amborella trichopoda	32.38	7.00e-24	103.00
IUUC-Aly-005918	Arabidopsis lyrata	88.79	5.00e-109	386.00
IUUC-Bdi-014533	Brachypodium distachyon	34.07	2.00e-24	105.00
IUUC-Bol-015819	Brassica oleracea	76.01	3.00e-95	341.00
IUUC-Bra-017550	Brassica rapa	72.52	4.00e-94	337.00
IUUC-Gma-043797	Glycine max	45.14	4.00e-46	177.00
IUUC-Hvu-047273	Hordeum vulgare	33.17	2.00e-23	102.00
IUUC-Lpe-051366	Leersia perrieri	38.36	5.00e-22	97.80
IUUC-Mtr-058394	Medicago truncatula	50.78	2.00e-49	188.00
IUUC-Mac-065570	Musa acuminata	47.90	9.00e-22	97.10
IUUC-Obr-076640	Oryza brachyantha	31.61	1.00e-17	83.20
IUUC-Ogl-077705	Oryza glaberrima	42.76	4.00e-20	91.30
IUUC-Ogu-078864	Oryza glumaepatula	43.15	2.00e-21	95.50
IUUC-Oin-079511	Oryza indica	42.76	2.00e-20	92.00
IUUC-Ome-081312	Oryza meridionalis	41.89	1.00e-19	89.70
IUUC-Oni-082796	Oryza nivara	42.76	4.00e-20	91.30
IUUC-Opu-083307	Oryza punctata	35.32	8.00e-22	97.10
IUUC-Oru-084702	Oryza rufipogon	42.76	4.00e-20	91.30
IUUC-Osa-085669	Oryza sativa	30.50	1.00e-19	90.10
IUUC-Pop-100094	Populus trichocarpa	54.65	3.00e-51	194.00
IUUC-Ppe-101209	Prunus persica	53.67	2.00e-53	201.00
IUUC-Sit-110129	Setaria italica	35.92	1.00e-19	90.50
IUUC-Sly-111858	Solanum lycopersicum	46.82	1.00e-44	172.00
IUUC-Stu-112105	Solanum tuberosum	47.89	7.00e-46	177.00
IUUC-Sbi-114578	Sorghum bicolor	39.31	9.00e-19	87.00
IUUC-Tca-120922	Theobroma cacao	60.46	9.00e-57	213.00
IUUC-Tae-124222	Triticum aestivum	34.33	2.00e-22	99.40
IUUC-Vvi-130862	Vitis vinifera	63.37	1.00e-33	135.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence