iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-090814

UUCD1 version

UUC-PaT-01090

Ensembl Protein ID

ENSPTRP00000027617.4

UniProt Accession

H2QPG6; H2QPG6_PANTR

Genbank Protein ID

JAA02279.1; JAA15140.1; JAA23571.1; JAA40341.1

Protein Name

Ubiquitin specific peptidase 46

Genbank Nucleotide ID

AACZ03033939; GABF01007005; GABD01009529; GABE01004398

Gene Name

USP46

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000016055.5	ENSPTRT00000029927.4	ENSPTRP00000027617.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.30e-98	330.3	35	364

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgy 87
           +Gl N+gNtCY+NSvLQ+L++++++re++l  +k +      +++k++ll++l++lf+++   k+k +++ p+++++ l+ke+  f++y
   Q: 35   FGLVNFGNTCYCNSVLQALYFCRPFRENVLA-YKAQ------QKKKENLLTCLADLFHSIAtqKKKVGVIPPKKFISRLRKENDLFDNY 116
           6******************************.3333......567899************976777779******************** PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpv 176
           +qqDa+Efl++ll+++ + l   ++++k+e+++ + ++ +++++ +++k + ++++++Fqg+l+++++cl+c++vss++e+fldls++v
   Q: 117  MQQDAHEFLNYLLNTIADIL---QEEKKQEKQNGKLKNGNMNEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDV 202
           ********************...34555555555556666677788888888************************************* PP
   S: 177  pgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfc 265
           ++++     s+++cL++f+++e+l++e+kyyce+c++kqea+k++++kklP +L lhLkRf++ e+ ++ +k++ +v fpleL l  f+
   Q: 203  EQNT-----SITHCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRVVFPLELRL--FN 284
           ****.....9**********************************************************************66555..77 PP
   S: 266  tspeekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetg.........staYvlfYkr 337
           ts++  ++ ++ Y+L+avvvH G +++ GHY+++vk+ +g WllfdD+ V++++ + ++e+ g         +++Y+lfY++
   Q: 285  TSSDA-VNLDRMYDLVAVVVHCGsGPNRGHYITIVKS-HGFWLLFDDDIVEKIDAQAIEEFYGltsdisknsESGYILFYQS 364
           77554.4459***************************.888*******************999*****************97 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MTVRNIASIC NMGTNASALE KDIGPEQFPI NEHYFGLVNF GNTCYCNSVL QALYFCRPFR 60
ENVLAYKAQQ KKKENLLTCL ADLFHSIATQ KKKVGVIPPK KFISRLRKEN DLFDNYMQQD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCTCCCTCC CCGCCCTCCC CGCGCCGCCG CCTCCTCCTC CCGGCCTCCC TCTCCCAGCC 60
AAACTGAAAG CCGGACCCCA GGCCGCCGCG CTGCCGCCCG GCCTCCCCGC CAGCGCGCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008343--P:adult feeding behavior
GO:0001662--P:behavioral fear response
GO:0048149--P:behavioral response to ethanol
GO:0016579--P:protein deubiquitination
GO:0032228--P:regulation of synaptic transmission, GABAergic
GO:0060013--P:righting reflex
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000193	Aegilops tauschii	60.00	8.00e-126	443.00
IUUC-Aml-002353	Ailuropoda melanoleuca	98.35	0.00e+00	704.00
IUUC-Atr-002650	Amborella trichopoda	59.56	8.00e-126	443.00
IUUC-Apl-003380	Anas platyrhynchos	95.63	0.00e+00	690.00
IUUC-Aca-005031	Anolis carolinensis	97.27	0.00e+00	750.00
IUUC-Aly-005830	Arabidopsis lyrata	58.92	1.00e-123	436.00
IUUC-Ath-006663	Arabidopsis thaliana	59.07	1.00e-126	446.00
IUUC-Ago-007871	Ashbya gossypii	38.57	8.00e-49	188.00
IUUC-Ame-010862	Astyanax mexicanus	94.85	0.00e+00	725.00
IUUC-Bta-013023	Bos taurus	98.61	0.00e+00	701.00
IUUC-Bdi-014008	Brachypodium distachyon	60.55	2.00e-125	441.00
IUUC-Bol-015138	Brassica oleracea	58.60	5.00e-125	440.00
IUUC-Bra-017483	Brassica rapa	60.34	2.00e-126	444.00
IUUC-Cel-018379	Caenorhabditis elegans	62.41	5.00e-145	507.00
IUUC-Cja-018956	Callithrix jacchus	97.55	0.00e+00	699.00
IUUC-Cfa-021064	Canis familiaris	99.44	0.00e+00	690.00
IUUC-Cpo-022443	Cavia porcellus	99.16	0.00e+00	699.00
IUUC-Cre-022711	Chlamydomonas reinhardtii	53.65	6.00e-100	357.00
IUUC-Csa-023841	Chlorocebus sabaeus	100.00	0.00e+00	724.00
IUUC-Csv-025828	Ciona savignyi	73.89	2.00e-88	319.00
IUUC-Cne-026900	Cryptococcus neoformans	41.91	4.00e-60	226.00
IUUC-Dre-028230	Danio rerio	94.34	0.00e+00	723.00
IUUC-Dno-029209	Dasypus novemcinctus	97.53	0.00e+00	702.00
IUUC-Dme-032038	Drosophila melanogaster	81.28	5.00e-100	357.00
IUUC-Eca-033721	Equus caballus	99.72	0.00e+00	696.00
IUUC-Eeu-034916	Erinaceus europaeus	98.64	3.00e-162	563.00
IUUC-Fca-036299	Felis catus	97.54	0.00e+00	701.00
IUUC-Fox-037682	Fusarium oxysporum	42.32	3.00e-74	273.00
IUUC-Fso-038299	Fusarium solani	37.07	9.00e-75	274.00
IUUC-Gmo-038611	Gadus morhua	94.63	0.00e+00	693.00
IUUC-Ggr-039806	Gaeumannomyces graminis	42.24	2.00e-75	276.00
IUUC-Gga-041157	Gallus gallus	98.63	0.00e+00	712.00
IUUC-Gac-041764	Gasterosteus aculeatus	93.94	0.00e+00	706.00
IUUC-Gma-042927	Glycine max	60.66	7.00e-128	449.00
IUUC-Ggo-044659	Gorilla gorilla	97.82	0.00e+00	702.00
IUUC-Hsa-046156	Homo sapiens	100.00	0.00e+00	724.00
IUUC-Hvu-047692	Hordeum vulgare	58.86	8.00e-124	436.00
IUUC-Itr-048157	Ictidomys tridecemlineatus	100.00	0.00e+00	724.00
IUUC-Kpa-049250	Komagataella pastoris	44.83	1.00e-69	257.00
IUUC-Lch-049969	Latimeria chalumnae	96.72	0.00e+00	685.00
IUUC-Lpe-051368	Leersia perrieri	58.70	9.00e-123	432.00
IUUC-Loc-052479	Lepisosteus oculatus	91.26	0.00e+00	694.00
IUUC-Laf-054085	Loxodonta africana	100.00	0.00e+00	724.00
IUUC-Mcc-055566	Macaca mulatta	98.08	0.00e+00	702.00
IUUC-Mor-057072	Magnaporthe oryzae	43.65	6.00e-76	278.00
IUUC-Mpo-057424	Magnaporthe poae	42.86	2.00e-75	277.00
IUUC-Mtr-057715	Medicago truncatula	60.33	3.00e-128	451.00
IUUC-Mla-059142	Melampsora laricipopulina	54.08	4.00e-96	346.00
IUUC-Mga-059575	Meleagris gallopavo	98.59	0.00e+00	686.00
IUUC-Mvi-060357	Microbotryum violaceum	53.96	2.00e-77	284.00
IUUC-Mdo-062579	Monodelphis domestica	99.73	0.00e+00	723.00
IUUC-Mmu-063611	Mus musculus	100.00	0.00e+00	724.00
IUUC-Mac-065323	Musa acuminata	60.11	3.00e-124	437.00
IUUC-Mpu-066038	Mustela putorius furo	100.00	0.00e+00	699.00
IUUC-Mlu-068183	Myotis lucifugus	98.08	0.00e+00	706.00
IUUC-Nle-069330	Nomascus leucogenys	100.00	0.00e+00	724.00
IUUC-Opr-070980	Ochotona princeps	99.72	0.00e+00	697.00
IUUC-Ont-072134	Oreochromis niloticus	95.12	0.00e+00	729.00
IUUC-Oan-073583	Ornithorhynchus anatinus	93.52	0.00e+00	686.00
IUUC-Ocu-074923	Oryctolagus cuniculus	99.72	0.00e+00	695.00
IUUC-Oba-075220	Oryza barthii	59.73	5.00e-123	434.00
IUUC-Obr-076208	Oryza brachyantha	57.65	6.00e-120	423.00
IUUC-Ogl-077216	Oryza glaberrima	59.73	5.00e-123	434.00
IUUC-Ogu-078836	Oryza glumaepatula	59.73	5.00e-123	434.00
IUUC-Oin-079522	Oryza indica	59.73	5.00e-123	434.00
IUUC-Olo-080882	Oryza longistaminata	59.73	5.00e-123	434.00
IUUC-Ome-081549	Oryza meridionalis	59.73	5.00e-123	434.00
IUUC-Oni-082982	Oryza nivara	59.73	5.00e-123	434.00
IUUC-Opu-083532	Oryza punctata	59.73	3.00e-123	434.00
IUUC-Oru-084568	Oryza rufipogon	59.73	5.00e-123	434.00
IUUC-Osa-085299	Oryza sativa	59.73	5.00e-123	434.00
IUUC-Ola-086546	Oryzias latipes	93.66	0.00e+00	705.00
IUUC-Olu-087809	Ostreococcus lucimarinus	48.44	1.00e-81	296.00
IUUC-Oga-088073	Otolemur garnettii	99.72	0.00e+00	696.00
IUUC-Oar-089248	Ovis aries	100.00	0.00e+00	698.00
IUUC-Pan-091753	Papio anubis	100.00	0.00e+00	724.00
IUUC-Psi-094012	Pelodiscus sinensis	99.15	0.00e+00	689.00
IUUC-Pma-094388	Petromyzon marinus	89.54	0.00e+00	689.00
IUUC-Ppa-095415	Physcomitrella patens	59.03	7.00e-128	450.00
IUUC-Pfo-097369	Poecilia formosa	95.12	0.00e+00	729.00
IUUC-Pab-098594	Pongo abelii	100.00	0.00e+00	701.00
IUUC-Pop-099798	Populus trichocarpa	60.38	5.00e-127	447.00
IUUC-Pca-100913	Procavia capensis	83.66	6.00e-160	556.00
IUUC-Ppe-101474	Prunus persica	59.84	4.00e-127	447.00
IUUC-Pva-102892	Pteropus vampyrus	100.00	0.00e+00	699.00
IUUC-Pgr-103306	Puccinia graminis	52.63	2.00e-94	340.00
IUUC-Rno-104909	Rattus norvegicus	99.73	0.00e+00	723.00
IUUC-Sce-106196	Saccharomyces cerevisiae	37.80	4.00e-55	209.00
IUUC-Sha-107400	Sarcophilus harrisii	99.72	0.00e+00	697.00
IUUC-Smo-109064	Selaginella moellendorffii	60.33	5.00e-121	427.00
IUUC-Sit-110819	Setaria italica	59.73	1.00e-123	435.00
IUUC-Sly-111210	Solanum lycopersicum	59.73	9.00e-127	446.00
IUUC-Stu-112398	Solanum tuberosum	60.16	4.00e-127	447.00
IUUC-Sbi-114562	Sorghum bicolor	58.90	7.00e-124	436.00
IUUC-Sre-115197	Sporisorium reilianum	48.94	2.00e-79	290.00
IUUC-Ssc-115550	Sus scrofa	100.00	0.00e+00	699.00
IUUC-Tgu-116800	Taeniopygia guttata	98.63	0.00e+00	713.00
IUUC-Tru-118212	Takifugu rubripes	95.12	0.00e+00	731.00
IUUC-Tni-120071	Tetraodon nigroviridis	95.12	0.00e+00	730.00
IUUC-Tca-121329	Theobroma cacao	60.11	2.00e-127	448.00
IUUC-Tae-125280	Triticum aestivum	60.27	1.00e-126	446.00
IUUC-Tur-126563	Triticum urartu	60.00	2.00e-126	444.00
IUUC-Uma-129409	Ustilago maydis	49.13	2.00e-81	297.00
IUUC-Vpa-130590	Vicugna pacos	94.93	0.00e+00	652.00
IUUC-Vvi-131371	Vitis vinifera	59.84	5.00e-127	447.00
IUUC-Xma-133111	Xiphophorus maculatus	95.12	0.00e+00	729.00
IUUC-Yli-134632	Yarrowia lipolytica	45.21	5.00e-79	289.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence