iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Ath-007269

UUCD1 version

UUC-ArT-01543

Ensembl Protein ID

AT3G53090.2

UniProt Accession

Q9SCQ2; Q0WUM3; UPL7_ARATH

Genbank Protein ID

CAB64212.1; AEE79035.1; AEE79036.1; BAE99175.1

Protein Name

E3 ubiquitin-protein ligase UPL7; HECT-type E3 ubiquitin transferase UPL7

Genbank Nucleotide ID

AL132958; CP002686; CP002686; AK227125

Gene Name

UPL7; At3g53090; T4D2.20

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT3G53090	AT3G53090.2	AT3G53090.2

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 activity/HECT	HECT	12969426

Classification

Family	E-value	Score	Start	End
E3 activity/HECT	1.70e-104	350.8	796	1142

Active Site

Position(s)	Description	Evidence
1110	Glycyl thioester intermediate	{ECO:0000255\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlpls 93
           s+lk++++v+fv+     E+gld+gG+++efl+ ++k+ + +++glf +++++++ l p+p++ +  ++ +++ eflGr++gkal++g lld+ +s
   Q: 796  SRLKSSIHVSFVNesglpEAGLDYGGLSKEFLTDITKAAFATEYGLFSQTPTSDRLLVPSPSARHL-ENGIQMIEFLGRIVGKALYEGILLDYSFS 890
           6899*********8888888*****************************************99865.5**************************** PP
   S: 94   ksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeq 189
           ++f+++llg+   +++l+ +dpely++l+++k++ + d++el  +l f+v+ee +g+++  eLkpgG++++VtneNk +Y++++++y+l+++i   
   Q: 891  HVFIQKLLGRYSFIDELSGLDPELYRNLMYVKHY-DGDLKEL--CLDFTVTEEFCGKMSIIELKPGGKDTSVTNENKMQYIHAMADYKLNRQIVPF 983
           **********9999********************.5677776..5556667999****************************************** PP
   S: 190  veafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelkp 284
            +af++G++++i++ +l+lF+++e+++l++G  ++idv+dl+++tky+ggy+++s++i+ Fwev+++f+  er+ +L+FvT++sr+Pl Gf++l+p
   Q: 984  SNAFYRGLTDLISPAWLKLFNAHEFNQLLSGGnHDIDVDDLRRNTKYTGGYSDSSRTIKIFWEVMKGFEPSERCLLLKFVTSCSRAPLLGFKYLQP 1079
           ******************************998**************************************************************8 PP
   S: 285  rlfvirk...........dasd.drlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
             f+i+k            ++d +rlPs++TC+n+LkLP+Y+  ++++ekLlyAi++++gFels
   Q: 1080 T-FIIHKvscdtslwaaiGGQDvERLPSASTCYNTLKLPTYKRASTMREKLLYAITSNAGFELS 1142
           8.999999*********955555**************************************985 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Probable E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins.

Protein Sequence
(Fasta)

MDLNRKHKVS LRGASSGEIS RDALLAKVSQ ERELRSYARR ANAASLFIQR VWRSYIVRKK 60
AAIEIQEEWE NLLSCHSVTL TKSWVSSRVL RPFLFFVRSL SVQHQKIQAR EIHCMQTCFK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGAAGAAGAA GAAGAAGAAG AAGAAGAAGA AGAAGAAGAA GAAGAAGATC GTGAGCCACT 60
ATATTCGCTT CCTTCCTCTA ATTTCCGATT CCAATGGACC TGAATCGCAA ACACAAGGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS
IPR027401--Myosin-like_IQ_dom

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

KEGG

ath:AT3G53090

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000128	Aegilops tauschii	55.51	0.00e+00	1062.00
IUUC-Aml-002107	Ailuropoda melanoleuca	39.29	2.00e-111	396.00
IUUC-Atr-003017	Amborella trichopoda	54.31	0.00e+00	1241.00
IUUC-Apl-003328	Anas platyrhynchos	39.46	2.00e-112	399.00
IUUC-Aly-005794	Arabidopsis lyrata	94.40	0.00e+00	2187.00
IUUC-Ago-007748	Ashbya gossypii	38.59	2.00e-76	279.00
IUUC-Acl-008158	Aspergillus clavatus	39.11	2.00e-75	277.00
IUUC-Afl-008398	Aspergillus flavus	39.75	3.00e-78	286.00
IUUC-Afu-008937	Aspergillus fumigatus	38.25	4.00e-76	279.00
IUUC-Ani-009252	Aspergillus nidulans	39.53	5.00e-85	309.00
IUUC-Ang-009773	Aspergillus niger	35.97	6.00e-75	275.00
IUUC-Aor-009940	Aspergillus oryzae	39.75	3.00e-78	286.00
IUUC-Ate-010395	Aspergillus terreus	37.68	2.00e-76	280.00
IUUC-Bgr-012269	Blumeria graminis	39.66	9.00e-76	276.00
IUUC-Bta-013547	Bos taurus	39.29	3.00e-112	399.00
IUUC-Bdi-014502	Brachypodium distachyon	53.60	0.00e+00	1149.00
IUUC-Bol-015093	Brassica oleracea	89.68	0.00e+00	2082.00
IUUC-Bra-016722	Brassica rapa	88.89	0.00e+00	2092.00
IUUC-Cel-018447	Caenorhabditis elegans	38.88	3.00e-98	352.00
IUUC-Cja-019855	Callithrix jacchus	39.29	5.00e-112	398.00
IUUC-Cfa-020066	Canis familiaris	38.57	1.00e-106	380.00
IUUC-Cpo-021504	Cavia porcellus	39.64	4.00e-113	402.00
IUUC-Cre-022673	Chlamydomonas reinhardtii	47.64	1.00e-117	417.00
IUUC-Csa-023579	Chlorocebus sabaeus	39.46	1.00e-112	400.00
IUUC-Cgl-026559	Colletotrichum gloeosporioides	38.56	2.00e-85	310.00
IUUC-Cne-026841	Cryptococcus neoformans	34.64	9.00e-87	314.00
IUUC-Dre-028271	Danio rerio	40.36	8.00e-114	404.00
IUUC-Dno-029054	Dasypus novemcinctus	39.11	1.00e-111	397.00
IUUC-Dor-030938	Dipodomys ordii	38.08	2.00e-105	376.00
IUUC-Dse-031416	Dothistroma septosporum	37.45	8.00e-79	288.00
IUUC-Dme-031602	Drosophila melanogaster	38.45	9.00e-107	381.00
IUUC-Eca-034411	Equus caballus	39.46	1.00e-112	400.00
IUUC-Eeu-035201	Erinaceus europaeus	34.18	4.00e-74	272.00
IUUC-Fca-036594	Felis catus	38.93	3.00e-111	395.00
IUUC-Fal-037317	Ficedula albicollis	39.46	2.00e-112	399.00
IUUC-Fox-037788	Fusarium oxysporum	38.26	9.00e-82	297.00
IUUC-Fso-038088	Fusarium solani	38.03	2.00e-81	296.00
IUUC-Gmo-039412	Gadus morhua	39.61	5.00e-110	392.00
IUUC-Gga-040149	Gallus gallus	39.46	1.00e-112	400.00
IUUC-Gac-042088	Gasterosteus aculeatus	39.82	4.00e-111	395.00
IUUC-Gma-042728	Glycine max	59.09	0.00e+00	1392.00
IUUC-Ggo-045279	Gorilla gorilla	39.29	5.00e-112	398.00
IUUC-Hsa-045660	Homo sapiens	39.29	6.00e-112	398.00
IUUC-Hvu-047102	Hordeum vulgare	54.94	0.00e+00	1051.00
IUUC-Lch-050664	Latimeria chalumnae	39.46	5.00e-111	395.00
IUUC-Lpe-050755	Leersia perrieri	48.54	0.00e+00	1008.00
IUUC-Loc-052791	Lepisosteus oculatus	39.93	3.00e-110	392.00
IUUC-Lma-053096	Leptosphaeria maculans	40.00	4.00e-83	302.00
IUUC-Laf-053902	Loxodonta africana	39.18	6.00e-112	398.00
IUUC-Mcc-054730	Macaca mulatta	39.46	1.00e-112	400.00
IUUC-Meu-056527	Macropus eugenii	34.88	5.00e-90	325.00
IUUC-Mor-057021	Magnaporthe oryzae	38.00	1.00e-74	274.00
IUUC-Mpo-057570	Magnaporthe poae	38.66	7.00e-79	288.00
IUUC-Mtr-057671	Medicago truncatula	58.35	0.00e+00	1364.00
IUUC-Mga-059260	Meleagris gallopavo	39.46	1.00e-112	400.00
IUUC-Mmr-060804	Microcebus murinus	39.29	5.00e-112	398.00
IUUC-Mdo-062575	Monodelphis domestica	39.46	3.00e-110	392.00
IUUC-Mmu-063636	Mus musculus	39.50	1.00e-111	397.00
IUUC-Mac-064989	Musa acuminata	52.75	0.00e+00	1130.00
IUUC-Mlu-067952	Myotis lucifugus	39.29	7.00e-112	398.00
IUUC-Nfi-068280	Neosartorya fischeri	38.25	3.00e-76	280.00
IUUC-Ncr-068869	Neurospora crassa	36.08	4.00e-86	312.00
IUUC-Nle-069153	Nomascus leucogenys	39.29	6.00e-112	398.00
IUUC-Opr-070554	Ochotona princeps	38.93	4.00e-110	392.00
IUUC-Ont-071372	Oreochromis niloticus	40.18	2.00e-112	400.00
IUUC-Ocu-074183	Oryctolagus cuniculus	39.29	3.00e-112	399.00
IUUC-Oba-075213	Oryza barthii	55.07	0.00e+00	992.00
IUUC-Obr-076320	Oryza brachyantha	52.48	0.00e+00	1084.00
IUUC-Ogl-077093	Oryza glaberrima	54.09	0.00e+00	1143.00
IUUC-Ogu-078235	Oryza glumaepatula	51.58	0.00e+00	1040.00
IUUC-Oin-080058	Oryza indica	53.22	0.00e+00	1112.00
IUUC-Olo-080742	Oryza longistaminata	53.55	0.00e+00	1161.00
IUUC-Ome-081741	Oryza meridionalis	52.28	0.00e+00	1089.00
IUUC-Oni-082616	Oryza nivara	51.66	0.00e+00	1052.00
IUUC-Opu-083529	Oryza punctata	53.71	0.00e+00	1017.00
IUUC-Oru-085128	Oryza rufipogon	53.26	0.00e+00	946.00
IUUC-Osa-085557	Oryza sativa	61.32	0.00e+00	877.00
IUUC-Ola-087337	Oryzias latipes	40.00	3.00e-111	396.00
IUUC-Olu-087902	Ostreococcus lucimarinus	46.14	1.00e-100	358.00
IUUC-Oga-088342	Otolemur garnettii	39.04	2.00e-110	393.00
IUUC-Oar-090234	Ovis aries	38.57	6.00e-107	381.00
IUUC-Ptr-091661	Pan troglodytes	39.11	1.00e-111	397.00
IUUC-Pan-092728	Papio anubis	39.22	8.00e-111	394.00
IUUC-Psi-093251	Pelodiscus sinensis	38.70	2.00e-97	350.00
IUUC-Pma-094195	Petromyzon marinus	39.65	1.00e-110	394.00
IUUC-Ppa-095544	Physcomitrella patens	64.14	0.00e+00	726.00
IUUC-Pfo-097472	Poecilia formosa	40.18	1.00e-112	400.00
IUUC-Pab-098570	Pongo abelii	39.29	8.00e-112	397.00
IUUC-Pop-099058	Populus trichocarpa	55.62	0.00e+00	909.00
IUUC-Pca-100110	Procavia capensis	36.79	1.00e-99	357.00
IUUC-Ppe-101281	Prunus persica	60.77	0.00e+00	1437.00
IUUC-Pva-102887	Pteropus vampyrus	37.14	1.00e-102	367.00
IUUC-Ptt-103967	Puccinia triticina	40.81	4.00e-83	302.00
IUUC-Rno-106028	Rattus norvegicus	37.59	1.00e-93	337.00
IUUC-Sce-106446	Saccharomyces cerevisiae	40.76	1.00e-73	270.00
IUUC-Sha-107331	Sarcophilus harrisii	39.29	1.00e-109	390.00
IUUC-Smo-109537	Selaginella moellendorffii	43.13	0.00e+00	852.00
IUUC-Sit-109811	Setaria italica	52.86	0.00e+00	1134.00
IUUC-Sly-111013	Solanum lycopersicum	57.90	0.00e+00	1305.00
IUUC-Sbi-114433	Sorghum bicolor	53.70	0.00e+00	1166.00
IUUC-Sre-115038	Sporisorium reilianum	43.60	7.00e-93	335.00
IUUC-Ssc-116103	Sus scrofa	39.29	1.00e-111	397.00
IUUC-Tgu-117275	Taeniopygia guttata	39.46	3.00e-112	399.00
IUUC-Tru-118681	Takifugu rubripes	39.82	1.00e-111	397.00
IUUC-Tni-120732	Tetraodon nigroviridis	41.32	7.00e-102	364.00
IUUC-Tca-121770	Theobroma cacao	61.16	0.00e+00	1382.00
IUUC-Tre-121892	Trichoderma reesei	41.70	1.00e-91	331.00
IUUC-Tvi-122354	Trichoderma virens	40.97	7.00e-88	318.00
IUUC-Tae-124300	Triticum aestivum	80.80	3.00e-139	486.00
IUUC-Tur-126086	Triticum urartu	53.75	0.00e+00	1039.00
IUUC-Tbe-127461	Tupaia belangeri	35.78	8.00e-88	318.00
IUUC-Ttr-129269	Tursiops truncatus	39.29	1.00e-111	397.00
IUUC-Vda-129748	Verticillium dahliae	36.74	4.00e-74	272.00
IUUC-Vvi-131524	Vitis vinifera	61.91	0.00e+00	1421.00
IUUC-Xtr-132146	Xenopus tropicalis	39.82	2.00e-112	400.00
IUUC-Xma-133526	Xiphophorus maculatus	40.18	1.00e-112	400.00
IUUC-Yli-134496	Yarrowia lipolytica	38.48	5.00e-84	305.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence