iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000016366.2	ENSMLUT00000023548.1	ENSMLUP00000020771.1
ENSMLUG00000016366.2	ENSMLUT00000016375.2	ENSMLUP00000014923.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	7.10e-12	45.2	4	59

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlvieke...eqdegWlkgvkelegkrGlfPenFve 60
            + +dye + d+eLtl++Gd v+v++++   + degW+ g +   g+ G+fP+++v+
   Q: 4    TAVFDYEVTGDEELTLRRGDRVQVLSQDcavSGDEGWWTG-RLPGGRVGVFPSDYVA 59
           589**********************77622257*******.58999*********97 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

PIWTAVFDYE VTGDEELTLR RGDRVQVLSQ DCAVSGDEGW WTGRLPGGRV GVFPSDYVAP 60
PRPAGPPASL PREIPFHELQ LEEIIGVGGF GKVYRALWRG EEVAVKAARL DPERDPAVTA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCATCTGGA CCGCGGTGTT CGACTACGAG GTGACGGGCG ACGAGGAGCT GACCCTGCGT 60
AGGGGGGACC GGGTCCAGGT GCTGTCCCAG GACTGTGCGG TGTCGGGCGA CGAGGGCTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome

Interpro

IPR011009--Kinase-like_dom
IPR015785--MAP3K10
IPR016231--MLK1/MLK2/MLK4
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR008271--Ser/Thr_kinase_AS
IPR001452--SH3_domain

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00220--S_TKc
SM00326--SH3

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0004709--F:MAP kinase kinase kinase activity
GO:0003714--F:transcription corepressor activity
GO:0043433--P:negative regulation of sequence-specific DNA binding transcription factor activity
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0018105--P:peptidyl-serine phosphorylation
GO:0018107--P:peptidyl-threonine phosphorylation
GO:0043507--P:positive regulation of JUN kinase activity
GO:0007224--P:smoothened signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001187	Ailuropoda melanoleuca	84.50	0.00e+00	896.00
IUUC-Atr-002967	Amborella trichopoda	31.96	2.00e-23	103.00
IUUC-Aca-004768	Anolis carolinensis	69.64	0.00e+00	772.00
IUUC-Aly-006459	Arabidopsis lyrata	32.38	5.00e-26	113.00
IUUC-Ath-006581	Arabidopsis thaliana	32.74	3.00e-26	114.00
IUUC-Bta-013545	Bos taurus	92.19	0.00e+00	779.00
IUUC-Bol-016287	Brassica oleracea	32.03	8.00e-26	112.00
IUUC-Bra-016997	Brassica rapa	33.33	6.00e-26	113.00
IUUC-Cja-019696	Callithrix jacchus	74.97	0.00e+00	1126.00
IUUC-Cfa-020789	Canis familiaris	70.18	0.00e+00	952.00
IUUC-Cpo-021993	Cavia porcellus	86.03	0.00e+00	904.00
IUUC-Csa-024243	Chlorocebus sabaeus	80.27	0.00e+00	1159.00
IUUC-Cho-024961	Choloepus hoffmanni	82.78	9.00e-97	347.00
IUUC-Dno-029095	Dasypus novemcinctus	79.25	0.00e+00	1092.00
IUUC-Fca-036250	Felis catus	84.37	0.00e+00	895.00
IUUC-Gma-043168	Glycine max	35.41	5.00e-24	106.00
IUUC-Ggo-045471	Gorilla gorilla	81.04	0.00e+00	825.00
IUUC-Hsa-046936	Homo sapiens	80.22	0.00e+00	1165.00
IUUC-Hvu-047818	Hordeum vulgare	31.64	3.00e-22	100.00
IUUC-Itr-048231	Ictidomys tridecemlineatus	86.33	0.00e+00	889.00
IUUC-Mcc-055733	Macaca mulatta	91.98	0.00e+00	818.00
IUUC-Mtr-057869	Medicago truncatula	32.74	4.00e-23	103.00
IUUC-Mdo-062516	Monodelphis domestica	67.88	0.00e+00	966.00
IUUC-Mmu-064082	Mus musculus	81.01	0.00e+00	1244.00
IUUC-Mac-065156	Musa acuminata	31.58	1.00e-25	111.00
IUUC-Mpu-065934	Mustela putorius furo	81.44	0.00e+00	1176.00
IUUC-Opr-070869	Ochotona princeps	68.19	0.00e+00	759.00
IUUC-Ocu-074350	Oryctolagus cuniculus	79.57	0.00e+00	1100.00
IUUC-Oba-075616	Oryza barthii	34.88	2.00e-22	101.00
IUUC-Obr-076215	Oryza brachyantha	34.91	1.00e-23	104.00
IUUC-Ogl-077159	Oryza glaberrima	34.88	2.00e-22	101.00
IUUC-Ogu-078228	Oryza glumaepatula	35.35	6.00e-23	102.00
IUUC-Oin-079079	Oryza indica	35.09	7.00e-23	102.00
IUUC-Oni-082428	Oryza nivara	34.88	2.00e-22	101.00
IUUC-Opu-083527	Oryza punctata	35.35	1.00e-22	101.00
IUUC-Oru-084678	Oryza rufipogon	35.09	7.00e-23	102.00
IUUC-Osa-086117	Oryza sativa	35.09	7.00e-23	102.00
IUUC-Oga-088351	Otolemur garnettii	78.88	0.00e+00	1185.00
IUUC-Ptr-091607	Pan troglodytes	80.33	0.00e+00	1167.00
IUUC-Pan-092403	Papio anubis	84.68	0.00e+00	859.00
IUUC-Pab-098396	Pongo abelii	82.68	0.00e+00	883.00
IUUC-Pop-100071	Populus trichocarpa	32.71	5.00e-22	99.80
IUUC-Ppe-101208	Prunus persica	35.24	1.00e-24	108.00
IUUC-Rno-105688	Rattus norvegicus	80.50	0.00e+00	1255.00
IUUC-Smo-109113	Selaginella moellendorffii	32.35	5.00e-24	105.00
IUUC-Sly-111849	Solanum lycopersicum	35.09	7.00e-24	105.00
IUUC-Stu-112224	Solanum tuberosum	35.09	1.00e-23	105.00
IUUC-Sbi-113963	Sorghum bicolor	34.58	6.00e-23	102.00
IUUC-Ssc-115332	Sus scrofa	84.85	0.00e+00	897.00
IUUC-Tru-117692	Takifugu rubripes	62.22	0.00e+00	770.00
IUUC-Tsy-119412	Tarsius syrichta	98.15	6.00e-60	225.00
IUUC-Tni-120689	Tetraodon nigroviridis	52.63	0.00e+00	793.00
IUUC-Tca-121565	Theobroma cacao	35.85	2.00e-24	107.00
IUUC-Tae-125555	Triticum aestivum	32.72	2.00e-23	104.00
IUUC-Ttr-128550	Tursiops truncatus	79.90	0.00e+00	1202.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence