iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xtr-132957

Ensembl Protein ID

ENSXETP00000044646.2

UniProt Accession

F7E859; F7E859_XENTR

Genbank Protein ID

ENSXETP00000044646

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

AAMC01036100

Gene Name

fgr

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000020659.3	ENSXETT00000044646.2	ENSXETP00000044646.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	9.20e-16	57.7	79	135

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           ++++lydy+a ++d+Lt+kkG++ ++i  ++ +++W+++ +  +g  G +P+n+v+ ++
   Q: 79   QFIALYDYDARTEDDLTFKKGEKFHII--NNSEGDWWEARSLSSGNTGYIPSNYVAPMN 135
           689************************..88999*********************9876 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MGCKQCKEDK VEKVEENALE IPQRYCPDPT SQMPFRIQET HTPFISAGIG GVIAGSSQRG 60
MGVGVTETKG GPRKGGVTQF IALYDYDART EDDLTFKKGE KFHIINNSEG DWWEARSLSS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGCTGCA AACAGTGTAA AGAAGATAAA GTGGAAAAGG TGGAGGAGAA TGCACTGGAG 60
ATCCCCCAGA GGTATTGTCC AGATCCCACA AGCCAGATGC CTTTTCGGAT TCAGGAAACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0031234--C:extrinsic component of cytoplasmic side of plasma membrane
GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0005102--F:receptor binding
GO:0030154--P:cell differentiation
GO:0016477--P:cell migration
GO:0045087--P:innate immune response
GO:0007229--P:integrin-mediated signaling pathway
GO:0038083--P:peptidyl-tyrosine autophosphorylation
GO:0042127--P:regulation of cell proliferation
GO:0007169--P:transmembrane receptor protein tyrosine kinase signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Meu-056155	Macropus eugenii	77.83	0.00e+00	751.00
IUUC-Mac-064539	Musa acuminata	32.84	1.00e-18	88.60
IUUC-Opu-083538	Oryza punctata	33.33	4.00e-23	103.00
IUUC-Sha-107103	Sarcophilus harrisii	79.18	0.00e+00	785.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence