iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sha-106552

Ensembl Protein ID

ENSSHAP00000017925.1

UniProt Accession

G3WR70; G3WR70_SARHA

Genbank Protein ID

ENSSHAP00000017925

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01157687

Gene Name

KDM5B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000015215.1	ENSSHAT00000018073.1	ENSSHAP00000017925.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.80e-21	76.2	242	288

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           vCl+Cg+g +++  l+ C+ C++ +H  Cl ++   ++p+ + w CpkC 
   Q: 242  VCLLCGSGNDED-RLLLCDGCDDSYHTFCLIPP-LHDVPKGD-WRCPKCL 288
           8********988.6*******************.*******7.******5 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

WQPPFACDVD KLHFTPRIQR LNELEAQTRV KLNFLDQIAK FWELQGCTLK IPHVERKILD 60
LFQLNRLVAE EGGFDVVCKE RKWTKIATKM GFAPGKAVGS HIRAHYERIL YPYNLFQSGA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGGCAACCAC CATTTGCGTG TGATGTTGAT AAACTTCATT TTACTCCTCG AATCCAGAGA 60
CTGAATGAAT TGGAGGTAAT GTTATGAATG AATATATGAA TATTATGTTT TAATTTTAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001606--ARID_dom
IPR003347--JmjC_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51011--ARID
PS51184--JMJC
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF01388--ARID
PF02373--JmjC
PF00628--PHD

SMART

SM00501--BRIGHT
SM00558--JmjC
SM00249--PHD

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0034648--F:histone demethylase activity (H3-dimethyl-K4 specific)
GO:0034647--F:histone demethylase activity (H3-trimethyl-K4 specific)
GO:0003714--F:transcription corepressor activity
GO:0008270--F:zinc ion binding
GO:0060444--P:branching involved in mammary gland duct morphogenesis
GO:0060763--P:mammary duct terminal end bud growth
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0010628--P:positive regulation of gene expression
GO:0033601--P:positive regulation of mammary gland epithelial cell proliferation
GO:0009791--P:post-embryonic development
GO:2000864--P:regulation of estradiol secretion
GO:0007338--P:single fertilization
GO:0061038--P:uterus morphogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bol-015336	Brassica oleracea	36.45	3.00e-14	75.50
IUUC-Cre-022637	Chlamydomonas reinhardtii	50.94	5.00e-08	48.50
IUUC-Cho-024823	Choloepus hoffmanni	94.36	0.00e+00	1185.00
IUUC-Eeu-035012	Erinaceus europaeus	78.07	0.00e+00	841.00
IUUC-Ggo-044856	Gorilla gorilla	74.30	0.00e+00	861.00
IUUC-Hvu-047583	Hordeum vulgare	43.04	1.00e-15	79.00
IUUC-Mdo-061957	Monodelphis domestica	95.34	0.00e+00	1227.00
IUUC-Mac-065069	Musa acuminata	35.14	6.00e-08	54.30
IUUC-Ogl-077886	Oryza glaberrima	38.83	3.00e-16	80.90
IUUC-Olo-080668	Oryza longistaminata	38.83	7.00e-16	80.90
IUUC-Osa-085487	Oryza sativa	38.83	3.00e-16	80.90
IUUC-Pab-097854	Pongo abelii	87.40	0.00e+00	1100.00
IUUC-Sce-106207	Saccharomyces cerevisiae	39.18	5.00e-74	272.00
IUUC-Tbe-127890	Tupaia belangeri	83.01	0.00e+00	653.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence