iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ptr-091439

Ensembl Protein ID

ENSPTRP00000041796.2

UniProt Accession

H2R156; H2R156_PANTR

Genbank Protein ID

ENSPTRP00000041796

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AACZ03067370

Gene Name

UBQLN1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000021055.6	ENSPTRT00000038941.3	ENSPTRP00000041796.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	4.30e-10	39.4	546	583
ULD/UDP/UBQ/UBQ_PIM	4.40e-25	87.4	37	110

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGF.dreealqaLraannnleaAveyLl 39
           ++++leql +MGF +re++lqaL a++++++aA+e+Ll
   Q: 546  FQQQLEQLSAMGFlNREANLQALIATGGDINAAIERLL 583
           799**********************************9 PP

ULD/UDP/UBQ/UBQ_PIM

   S: 1    mkltvktlkgkefelevseddtveelKekiakesgvppeqqkLIyaGkiLkDdttLselgikdgsvvhlvvkksk 75
           mk+tvkt+k+ke e+ v e+++v+++Ke+i+k+++ + +q+ LI+aGkiLkD++tLs++gi+dg +vhlv+k+++
   Q: 37   MKVTVKTPKEKE-EFAVPENSSVQQFKEEISKRFKSHTDQLVLIFAGKILKDQDTLSQHGIHDGLTVHLVIKTQN 110
           99**********.***********************************************************987 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MAESGESGGP PGSQDSAAGA EGAGAPAAAA SAEPKIMKVT VKTPKEKEEF AVPENSSVQQ 60
FKEEISKRFK SHTDQLVLIF AGKILKDQDT LSQHGIHDGL TVHLVIKTQN RPQDHSAQQT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGAGGAGGA AGCGGTGGCT GCTGCGGATG TCGGTGTGAG CGAGCGGCGC CTGAACACAC 60
GGCGGCTGCC GAGCGCCTGA CCCGGGCCTG CGCCAGAGCC TGCACCGAGC TCCGGGGCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006636--STI1_HS-bd
IPR015940--UBA
IPR009060--UBA-like
IPR015496--Ubiquilin
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50030--UBA
PS50053--UBIQUITIN_2

Pfam

PF00627--UBA
PF00240--ubiquitin

SMART

SM00727--STI1
SM00165--UBA
SM00213--UBQ

Gene Ontology

GO:0016235--C:aggresome
GO:0005776--C:autophagosome
GO:0005829--C:cytosol
GO:0005783--C:endoplasmic reticulum
GO:0005654--C:nucleoplasm
GO:0048471--C:perinuclear region of cytoplasm
GO:0005886--C:plasma membrane
GO:0043234--C:protein complex
GO:0035973--P:aggrephagy
GO:0000045--P:autophagosome assembly
GO:0097352--P:autophagosome maturation
GO:0071456--P:cellular response to hypoxia
GO:1901340--P:negative regulation of store-operated calcium channel activity
GO:0034140--P:negative regulation of toll-like receptor 3 signaling pathway
GO:1903071--P:positive regulation of ER-associated ubiquitin-dependent protein catabolic process
GO:0031398--P:positive regulation of protein ubiquitination
GO:1902175--P:regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000864	Aegilops tauschii	49.65	3.00e-36	146.00
IUUC-Aml-001461	Ailuropoda melanoleuca	95.70	0.00e+00	804.00
IUUC-Atr-002470	Amborella trichopoda	39.78	1.00e-42	167.00
IUUC-Apl-003241	Anas platyrhynchos	83.58	0.00e+00	712.00
IUUC-Aca-004511	Anolis carolinensis	80.11	0.00e+00	719.00
IUUC-Aly-005419	Arabidopsis lyrata	34.28	3.00e-50	192.00
IUUC-Ath-007350	Arabidopsis thaliana	34.92	2.00e-53	203.00
IUUC-Ago-007963	Ashbya gossypii	37.68	1.00e-08	53.90
IUUC-Bta-013048	Bos taurus	94.38	0.00e+00	823.00
IUUC-Bdi-014506	Brachypodium distachyon	35.45	1.00e-50	194.00
IUUC-Bol-015326	Brassica oleracea	33.57	6.00e-51	195.00
IUUC-Bra-018014	Brassica rapa	38.41	4.00e-40	159.00
IUUC-Cel-018631	Caenorhabditis elegans	38.24	1.00e-65	243.00
IUUC-Cja-019976	Callithrix jacchus	97.84	0.00e+00	839.00
IUUC-Cfa-020092	Canis familiaris	95.86	0.00e+00	828.00
IUUC-Cpo-022388	Cavia porcellus	95.86	0.00e+00	825.00
IUUC-Csa-024087	Chlorocebus sabaeus	99.09	0.00e+00	840.00
IUUC-Cho-024834	Choloepus hoffmanni	96.34	0.00e+00	840.00
IUUC-Cin-025136	Ciona intestinalis	50.92	2.00e-111	396.00
IUUC-Dno-028970	Dasypus novemcinctus	78.37	0.00e+00	669.00
IUUC-Dor-030519	Dipodomys ordii	92.27	0.00e+00	798.00
IUUC-Dme-032013	Drosophila melanogaster	46.57	2.00e-113	402.00
IUUC-Ete-032273	Echinops telfairi	94.90	0.00e+00	805.00
IUUC-Eca-033667	Equus caballus	94.57	0.00e+00	827.00
IUUC-Fca-036179	Felis catus	92.63	0.00e+00	785.00
IUUC-Fal-037642	Ficedula albicollis	82.65	0.00e+00	769.00
IUUC-Gga-041264	Gallus gallus	83.51	0.00e+00	799.00
IUUC-Gma-043430	Glycine max	34.73	1.00e-42	167.00
IUUC-Ggo-044969	Gorilla gorilla	99.46	0.00e+00	820.00
IUUC-Hsa-046669	Homo sapiens	99.64	0.00e+00	852.00
IUUC-Itr-048337	Ictidomys tridecemlineatus	96.48	0.00e+00	682.00
IUUC-Lch-050192	Latimeria chalumnae	77.26	0.00e+00	670.00
IUUC-Lpe-051401	Leersia perrieri	37.70	5.00e-35	142.00
IUUC-Loc-052846	Lepisosteus oculatus	77.43	0.00e+00	664.00
IUUC-Lma-053152	Leptosphaeria maculans	30.29	2.00e-11	63.90
IUUC-Laf-054278	Loxodonta africana	94.40	0.00e+00	790.00
IUUC-Mcc-055680	Macaca mulatta	99.10	0.00e+00	852.00
IUUC-Meu-056414	Macropus eugenii	79.64	1.00e-154	539.00
IUUC-Mtr-058674	Medicago truncatula	35.20	1.00e-45	177.00
IUUC-Mga-059894	Meleagris gallopavo	82.64	0.00e+00	642.00
IUUC-Mmr-061094	Microcebus murinus	96.94	0.00e+00	826.00
IUUC-Mdo-062728	Monodelphis domestica	86.20	0.00e+00	769.00
IUUC-Mmu-064088	Mus musculus	85.98	0.00e+00	828.00
IUUC-Mac-065526	Musa acuminata	32.93	2.00e-43	170.00
IUUC-Mpu-066282	Mustela putorius furo	92.09	0.00e+00	798.00
IUUC-Mlu-068158	Myotis lucifugus	94.05	0.00e+00	790.00
IUUC-Nle-069321	Nomascus leucogenys	99.46	0.00e+00	852.00
IUUC-Opr-071098	Ochotona princeps	89.70	3.00e-180	624.00
IUUC-Oan-072808	Ornithorhynchus anatinus	86.64	0.00e+00	735.00
IUUC-Ocu-074301	Oryctolagus cuniculus	87.77	0.00e+00	783.00
IUUC-Oba-074973	Oryza barthii	39.02	5.00e-42	165.00
IUUC-Obr-076444	Oryza brachyantha	50.34	6.00e-31	129.00
IUUC-Ogl-077319	Oryza glaberrima	39.02	2.00e-42	167.00
IUUC-Ogu-078074	Oryza glumaepatula	35.29	1.00e-49	190.00
IUUC-Oin-079142	Oryza indica	38.36	1.00e-42	167.00
IUUC-Olo-080565	Oryza longistaminata	35.29	1.00e-47	184.00
IUUC-Ome-081155	Oryza meridionalis	46.63	5.00e-33	135.00
IUUC-Oni-082272	Oryza nivara	38.36	1.00e-42	167.00
IUUC-Opu-083241	Oryza punctata	36.75	4.00e-50	192.00
IUUC-Oru-085257	Oryza rufipogon	38.36	1.00e-42	167.00
IUUC-Osa-086257	Oryza sativa	39.02	1.00e-42	167.00
IUUC-Olu-087597	Ostreococcus lucimarinus	32.12	5.00e-24	105.00
IUUC-Oga-088495	Otolemur garnettii	96.40	0.00e+00	801.00
IUUC-Oar-089711	Ovis aries	94.06	0.00e+00	798.00
IUUC-Pan-092641	Papio anubis	99.10	0.00e+00	852.00
IUUC-Psi-093518	Pelodiscus sinensis	83.15	0.00e+00	714.00
IUUC-Pma-094727	Petromyzon marinus	41.44	1.00e-52	201.00
IUUC-Pfo-096638	Poecilia formosa	67.68	2.00e-172	598.00
IUUC-Pab-098699	Pongo abelii	97.30	0.00e+00	844.00
IUUC-Pop-099549	Populus trichocarpa	37.10	1.00e-53	204.00
IUUC-Pca-100497	Procavia capensis	83.52	2.00e-133	469.00
IUUC-Ppe-101901	Prunus persica	35.00	1.00e-55	210.00
IUUC-Pva-102513	Pteropus vampyrus	83.48	2.00e-145	509.00
IUUC-Rno-104908	Rattus norvegicus	86.15	0.00e+00	865.00
IUUC-Sha-106881	Sarcophilus harrisii	84.33	0.00e+00	694.00
IUUC-Smo-108910	Selaginella moellendorffii	36.15	1.00e-36	147.00
IUUC-Sit-110766	Setaria italica	39.67	3.00e-35	143.00
IUUC-Sar-113648	Sorex araneus	87.68	0.00e+00	627.00
IUUC-Sbi-114307	Sorghum bicolor	37.79	1.00e-43	171.00
IUUC-Ssc-115820	Sus scrofa	96.40	0.00e+00	832.00
IUUC-Tgu-116845	Taeniopygia guttata	78.38	0.00e+00	683.00
IUUC-Tni-119780	Tetraodon nigroviridis	65.60	4.00e-169	587.00
IUUC-Tca-121558	Theobroma cacao	35.31	6.00e-53	202.00
IUUC-Tae-125518	Triticum aestivum	49.65	7.00e-37	148.00
IUUC-Tur-126783	Triticum urartu	54.41	4.00e-37	149.00
IUUC-Tbe-127379	Tupaia belangeri	83.21	0.00e+00	669.00
IUUC-Ttr-128630	Tursiops truncatus	93.41	0.00e+00	835.00
IUUC-Vpa-130413	Vicugna pacos	70.73	2.00e-158	552.00
IUUC-Vvi-131599	Vitis vinifera	39.80	2.00e-41	163.00
IUUC-Xtr-132595	Xenopus tropicalis	79.15	0.00e+00	703.00
IUUC-Xma-134155	Xiphophorus maculatus	64.66	3.00e-167	581.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence